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Impact of socioeconomic and health-related factors on consumption of homeopathic and natural remedies in Spain in 2006, 2011 and 2017

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journal of Integrative Medicine 2022年第1期20卷 52-56页

作者： jose Antonio Castilla-jimena isabel Ruiz-Perez jesus Henares-Montiel Andalusian School of Public Health 1801J GranadaSpain Unit of Clinical Management of Preventive Medicine and Public Health and Occupational Medicine Puerto del Mar University Hospital11009 CadizSpain Consortium for Networked Biomedical Research in Epidemiology and Public Health 28029 MadridSpain Institute for Biosanitary Research(ibs.GRANADA) 18012 GranadaSpain

Objective: Complementary and alternative medicine use and type of use may be influenced by sociodemographic and economic determinants through which we could identify characteristics of patients with greater trend to use it. This paper aims to describe the changes in the consumption of homeopathic and natural remedies in Spain for three time points in order to discern changes in rate of consumption, associated factors and whether their use has been affected by a period of economic ***: This study utilized 2006, 2011 and 2017 cross-sectional data from the Spanish National Health Survey, a nationally representative survey of the population aged more than 15 years old and resident in Spain. Independent bivariate and multivariate descriptive analyses for each of the 3 years studied were ***: The rate of consumption of both homeopathic and natural remedies has decreased over the periods studied. In spite of this decrease, the consumer profile appears to remain stable over the three periods. The sociodemographic factors associated with their consumption were being female, being 30–64 years old, being separated/divorced, having higher education qualifications, being employed and belonging to a higher social class. Psychiatric morbidity, chronic health problems such as pain, mental health problems or malignant tumors, and absence of major cardiovascular events were the clinical factors ***: It can be concluded that beyond the economic situation, the use of homeopathic and natural remedies obeys to the needs of the patients related to their state of health and the response they receive from the health system. It may be that women have different needs and expectations of the healthcare system and, given this breach of expectations, seek remedy to alleviate their needs outside the system and conventional medicine.

关键词： Complementary and alternative medicine Homeopathic remedies Natural remedies Economic recession Gender differences

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Protic ionic liquids/poly(vinylidene fluoride) composite membranes for fuel cell application

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journal of Energy Chemistry 2021年第2期30卷 197-207,I0008页

作者： isabel Vazquez-Fernandez Mohamed Raghibi Adnane Bouzina Laure Timperman janick Bigarre Meriem Anouti Laboratoire KM2E Parc de GrandmontUniversite de Tours37200ToursFrance CEA-DAM Le Ripault BP16F-37260MontsFrance

Poly(vinylidene fluoride), PVDF, membranes have attracted considerable attention as polymer electrolytes for fuel cells. This study explores the effect of solvent on the spherulite size and the crystallinity of the polymeric membranes. Based on Hansen solubility parameters theory, the mixture of DMC and DMSO was selected among a dozen of solvents for the preparation of PVDF membranes by thermally induced phase separation. The addition of two protic ionic liquids(PILs), bis(2-ethyl hexyl) ammonium hydrogen phosphate [EHNH_2][H_2PO_4], and imidazolium hexanoate [Im][Hex] to PVDF membranes at concentrations(10% < wP IL< 50%) has been investigated by SEM, FTIR, DSC, TGA, EIS, and DMA. The inclusion of ionic liquids into the polymer matrix influences structural parameters(degree of crystallinity and electroactive phases), thermal stability, proton conductivity and mechanical properties of the membranes. The membranes become transparent regardless type of ionic liquid employed. A small amount of ionic liquids increases the degree of crystallinity and facilitates the production of polar β and γ crystals. The proton conductivity mechanism(Grotthuss) is dependent on the ionic liquid structure(due to its selforganization in water) and the content in the PVDF membrane, as well as the membrane water *** behavior has been observed for the two ionic liquids, which stresses the challenge on selecting an appropriate cation and anion combination. The obtained composite membranes exhibited excellent mechanical performance and reduced elastic modulus, with respect to the pure polymer matrix. These results indicate that PVDF/IL composite membranes have a high potential for PEMFC applications.

关键词： PVDF Hansen solubility parameters PILs Proton conductivity

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Hydrogen Storage by Titanium Based Sulfides： Nanoribbons （TiS3） and Nanoplates （TiS2）

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journal of Electrical Engineering 2015年第1期3卷 24-29页

作者： Mariam Barawi Eduardo Flores Marine Pomhieu jose Ramon Ares Fermin Cuevas Fabrice Leardini isabel jimenez ferrer Carlos Sanchez Mire Group Science Faculty Autonomous University of Madrid Madrid 28012 Spain CEA LITEN Hydrogen Biomass Thermal Department Grenoble F-38054 France CMTR/ICMPE/CNRS-UPEC UMR7182 2-8 rue Henri Dunant Thiais Cedex 94320 France

Nowadays, finding cheap and non-toxic materials able to reversibly store high amounts of hydrogen is a challenge in the renewable energy field. Metal sulfides seem to be promising candidates to this purpose. Titanium sulfides are reported to be particularly interesting but their ability to store hydrogen remains unclear. In this work, titanium based sulfides TiS2 and TiS3 with two-dimensional nanostructures have been synthesized by solid-gas reaction between titanium powder and sulfur at temperatures between 500-600℃. The morphology and crystal structure of Ti-sulfides were characterized by SEM （scanning electronic microscopy） equipped with EDX （energy dispersion X-ray） and XRD （X-ray diffraction）, respectively. Their thermal stability was examined by TGA （thermal gravimetric analysis）. Their hydrogenation properties have been determined by manometric means using a Sieverts system and by DSC-HP （high-pressure differential scanning calorimetric）. Ti-sulfides hardly absorb/adsorb hydrogen for hydrogen pressures up to 80 bar and reaction temperatures up to 300℃.

关键词： Hydrogen storage titanium-sulfide nanoribbons nanoplates layer compounds.

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Assessing the estrogenic potency in a Portuguese wastewater treatment plant using an integrated approach

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journal of Environmental Sciences 2010年第10期22卷 1613-1622页

作者： Mário S.Diniz Rita Maurício Mira Petrovic Maria j.López De Alda Leonor Amaral isabel Peres Damiá Barceló Fernando Santana Universidade Nova de Lisboa Faculdade de Ciencias e TecnologiaREQUIMTEDep.de Quimica Universidade Nova de Lisboa Faculdade de Ciencias e TecnologiaDep.de Ciencias e Engenharia do Ambiente Department of Environmental Chemistry-IIQAB-CSIC c/jordi Girona

The estrogenic potency of a wastewater treatment plant （WWTP） was evaluated using chemical and biological analyses, which showed that after the station treatment processes some of the selected endocrine disruptor compounds （EDCs） were still present in the treated effluent （e.g., bisphenol A, alkylphenols, estrone）. Thus, the most common endocrine EDCs were identified and quantified and the overall estrogenicity of the treated effluent assessed by integrating the results. Male goldfish （Carassius auratus） were used as biological indicators in a 28-day experiment. Vitellogenin （Vtg）, gonadosomatic and hepatosomatic indices, steroids （17β-estradiol and 11-ketotestosterone） and histopathology were biomarkers used in fish to evaluate WWTP treated effluent estrogenicity, in combination with instrumental analyses. The results showed a significant increase （P 〈 0.01） in plasma and liver Vtg, which were significantly correlated （r = 0.66; P 〈 0.01）. The gonadosmatic index was significantly （P 〈 0.01） reduced in exposed fish. The steroid analyses revealed significant elevations in 17β-estradiol and depressed 11-ketotestosterone concentrations. The histological examinations show changes in exposed fish gonads, such as regressed testes and in some cases （43% to 75%） the development of ovo-testis in fish exposed to 50% and 100% treated effluent.

关键词： Carassius auratus endocrine disruptors vitellogenin steroids intersex

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Shallow landslide susceptibility assessment under future climate and land cover changes: A case study from southwest China

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Geoscience Frontiers 2023年第4期14卷 21-41页

作者： Zizheng Guo joaquin Vicente ferrer Marcel Hürlimann Vicente Medina Carol Puig-Polo Kunlong Yin Da Huang School of Civil and Transportation Engineering Hebei University of Technology300401 TianjinChina Division of Geotechnical Engineering and Geosciences Department of Civil and Environmental EngineeringUPC BarcelonaTECH08034 BarcelonaSpain Faculty of Engineering China University of Geosciences430074 WuhanChina Institute of Environmental Science and Geography University of Potsdam14476 PotsdamGermany Potsdam Institute for Climate Impact Research 14473 PotsdamGermany College of Geological Engineering and Geomatics Chang’an University710064 Xi’anChina

There is no doubt that land cover and climate changes have consequences on landslide activity,but it is still an open issue to assess and quantify their *** County in southwest China was selected as the test area to study rainfall-induced shallow landslide susceptibility under the future changes of land use and land cover(LULC)and *** used a high-resolution meteorological precipitation dataset and frequency distribution model to analyse the present extreme and antecedent rainfall conditions related to landslide *** future climate change factors were obtained from a 4-member multimodel ensemble that was derived from statistically downscaled regional climate *** future LULC maps were simulated by the land change modeller(LCM)integrated into IDRISI Selva software.A total of six scenarios were defined by considering the rainfall(antecedent conditions and extreme events)and LULC changes towards two time periods(mid and late XXI century).A physically-based model was used to assess landslide susceptibility under these different *** results showed that the magnitude of both antecedent effective recharge and event rainfall in the region will evidently increase in the *** the scenario with a return period of 100 years,the antecedent rainfall in summer will increase by up to 63%whereas the event rainfall will increase by up to 54%for the late 21st *** most considerable changes of LULC will be the increase of forest cover and the decrease of farming *** magnitude of this change can reach+22.1%(forest)and–9.2%(farmland)from 2010 until 2100,*** found that the negative impact of climate change on landslide susceptibility is greater than the stabilizing effect of LULC change,leading to an over decrease in stability over the study *** is one of the first studies across Asia to assess and quantify changes of regional landslide susceptibility under scenarios driven by LULC and climate ***

关键词： Rainfall-induced landslide Susceptibility Climate change Land cover change China

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The function of animal ‘eyespots’:Conspicuousness but not eye mimicry is key

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Current Zoology 2009年第5期55卷 319-326页

作者： Martin STEVENS Abi CANTOR julia GRAHAM isabel S.WINNEY Department of Zoology University of CambridgeDowning Street

Many animals are marked with conspicuous circular features often called ＇eyespots＇, which intimidate predators, preventing or halting an attack. It has long been assumed that eyespots work by mimicking the eyes of larger animals, but recent experiments have indicated that conspicuousness and contrast is important in eyespot function, and not eye mimicry. We undertake two further experiments to distinguish between the conspicuousness and mimicry hypotheses, by using artificial prey presented to wild avian predators in the field. In experiment 1, we test if eyespot effectiveness depends on the marking shape （bar or circle） and arrangement （eye-like and non-eye-like positions）. We find no difference between shapes or arrangement; all spots were equally effective in scaring birds. In experiment 2, we test if the often yellow and black colors of eyespots mimic the eyes of birds of prey. We find no effect of shape, and no advantage to yellow and black spots over non-eye-like but equally conspicuous colors. The consistent finding is that eyespot function lies in being a conspicuous signal to predators, and not necessarily due to eye mimicry [ Current Zoology 55 （5）： 319 - 326, 2009].

关键词： Eyespots Conspicuousness Mimicry Predation Protective coloration

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Prolonged cholestasis after raloxifene and fenofibrate interaction: A case report

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World journal of Gastroenterology 2006年第32期12卷 5244-5246页

作者： M isabel Lucena Raúl j Andrade Luis Vicioso F jesús González Ketevan Pachkoria Beatriz García-Mu(n|~)oz Clinical Pharmacology Service Virgen de la Victoria University Hospital School of MedicineMalagaSpain Liver Unit Gastroenterology Service Virgen de la Victoria University HospitalSchool of MedicineMálagaSpain Department of Pathology Virgen de la Victoria University Hospital School of MedicineMálagaSpain Institute of Biopathology and Regenerative Medicine University of Granada Spain Clinical Pharmacology Service Virgen de la Victoria University Hospital School of MedicineMálagaSpain

Assigning causality in drug-induced liver injury is challenging particularly when more than one drug could be responsible. We report a woman on long-term therapy with raloxifen who developed acute cholestasis shortly after starting fenofibrate. The picture evolved into chronic cholestasis. We hypothesized that an interaction at the metabolic level could have triggered the presentation of hepatotoxicity after a very short time of exposure to fenofibrate in this patient. The findings of an overexpression of vascular endothelial growth factor in the liver biopsy suggest that angiogenesis might play a role in the persistance of toxic cholestasis.

关键词： Raloxifene Fenofibrate Drug-drug interactions Hepatotoxicity Causality assessment

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Intraexaminer repeatability and agreement in stereoacuity measurements made in young adults

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International journal of Ophthalmology(English edition) 2015年第2期8卷 374-381页

作者： Beatriz Antona Ana Barrio isabel Sanchez Enrique Gonzalez Guadalupe Gonzalez Department of Optics II (Optometry and Vision) Faculty of Optics and Optometry Complutense University of Madrid

AIM: To determine the repeatability and agreement of stereoacuity measurements made using some of the most widely used clinical tests: Frisby, TNO, Randot and ***: Stereoacuity was measured in two different sessions separated by a time interval of at least 24 h but no longer than 1wk in 74 subjects of mean age 20.6y using the four methods. The study participants were divided into two groups: subjects with normal binocular vision and subjects with abnormal binocular ***: Best repeatability was shown by the Frisby and Titmus [coefficient of repeatability(COR): ±13 and±12s arc respectively] in the subjects with normal binocular vision though a clear ceiling effect was *** the subjects with abnormal binocular vision, best repeatability was shown by the Frisby(COR: ±69s arc)and Randot(COR: ±72s arc). In both groups, the TNO test showed poorest agreement with the other ***:Therepeatabilityofstereoacuitymeasures was low in subjects with poor binocular vision yet fairly good in subjects with normal binocular vision with the exception of the TNO test. The reduced agreement detected between the tests indicates they cannot be used interchangeably.

关键词： stereoacuity repeatability agreement tereopsis

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Adverse hepatic reactions associated with calcium carbimide and disulfiram therapy: Is there still a role for these drugs?

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World journal of Gastroenterology 2006年第31期12卷 5078-5080页

作者： Carmen Verge M isabel Lucena Enrique López-Torres M josé Puche-García Enrique Fraga Manuel Romero-Gomez Raúl j Andrade Clinical Pharmacology ServiceVirgen de la Victoria University Hospital School of MedicineMálagaSpain Gastroenterology ServiceUniversity Hospital Reina Sofia CórdobaSpain Gastroenterology ServiceUniversity Hospital Virgen de Valme SevillaSpain Liver UnitDepartment of Gastroenterology University HospitalMálagaSpain

Disulfiram and calcium carbimide are two alcohol deterrants widely used in alcoholism treatment, however, there exist great concerns over their safety. Reports on hepatotoxicity, mainly related to disulfiram therapy, have been published. The hepatotoxic potential of calcium carbimide is less well characterized. Here, we describe four cases of liver damage related to this therapeutic group that were submitted to a Registry of hepatotoxicity and point out the limitations that we face when prescribing these compounds. A reassessment of the role of these compounds in the management of alcohol dependence is clearly needed.

关键词： Calcium carbimide Disulfiram Hepatotoxicity

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Remediation of amide pesticide-polluted soils by combined solarization and ozonation treatment

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Pedosphere 2024年第3期34卷 641-651页

作者： isabel GARRIDO Carmen MMARTINEZ Pilar FLORES Pilar HELLIN Fulgencio CONTRERAS jose FENOLL Department of Sustainability and Quality Group of Fruit and Vegetable Products Instituto Murciano de Investigacion y Desarrollo Agrario y MedioambientalLa Alberca 30150(Spain)

Agriculture has a close relationship with nature,but it can also be the source of negative and permanent environmental *** use of pesticides in modern agriculture is a common practice,but their side effects on the environment cannot be *** this study,we evaluated a combination of solarization and ozonation techniques for the elimination of six amide pesticides(boscalid,chlorantraniliprole,cyflufenamid,fluopyram,napropamide,and propyzamide)in *** experiments were performed with four different soils to assess the efficiency of this methodology at different soil temperatures and ozone dosages under laboratory conditions,and then a greenhouse pot experiment was conducted under controlled conditions during *** days after the onset of the experiments,higher degradation percentages of amide pesticides were observed in ozonized soils than in other treated soils,particularly when ozone was applied at 10 cm soil *** results show that the utilization of ozonation,along with solarization,represents a valid method for degrading residues of the studied pesticides and suggest that this combined technology may be a promising tool for remediating pesticide-polluted soils.

关键词： intermediate ozone pesticide degradation pesticide residue polyethylene film remediation technique

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