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Enrichment of Resveratrol in Wine through a New Vinification Procedure

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Journal of Life Sciences 2015年第7期9卷 327-333页

作者： Raul Francisco Pastor Magdalena Raquel Gargantini Marcelo Murgo Sebastian Prieto humberto Manzano Carla Aruani Claudia In6s Quini Maria-isabel Covas Roberto h6ctor Iermoli Section Polyphenols Wine and Health Fourth Chair in Internal Medicine Clinics Hospital University of Buenos Aires BuenosAires C1408FZB Argentina Department Special Analytical Standards National Wine Institute Mendoza M5500AAR Argentina Department Oenological and Sensory Studies National Wine Institute Mendoza M5500AAR Argentina NUPROAS handesbolag Sicka Alle Nacka 13165 Sweden

Sulphur dioxide is used in the vinification process as an antimicrobial agent, but it is also considered as an important risk factor for liver diseases. Stilbenes have inhibitory effects on the growth of lactic acid bacteria strains isolated from wine. The authors investigated the viability of obtaining free-SO2 resveratrol-enriched red wines. Substitution of sulfite （7 g/100kg） for resveratrol （150 mg/L and 300 mg/L） in the vinification process did not change the basic physical and chemical properties of wine or its sensorial profile To the best of the authors＇ knowledge this is the first time that this type of vinification procedure is reported.

关键词： Vinification sulfur dioxide resveratrol wine enrichment.

Effect of Thermal Processing, Press Throughput and Roller-Die Gap on Physicochemical Properties of Broiler Feed Pellets

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Journal of Agricultural Science and Technology(A) 2016年第2期6卷 98-107页

作者： Keysuke Muramatsu isabel Cristina Mores Vaccari Cibele Silva Minafra Rafael Femando Sens FabianoDahlke Alex Maiorka DSM Nutritional Products Av. Eng. Billings 1729 Sao Paulo 05321-010 Brazil Instituto Federal Goiano Rio Verde Goias 75901-970 Brazil BRF-Rodovia BR 277 3001 Mossungue Curitiba 82305-100 Brazil Universidade Federal de Santa Catarina (UFSC) Rod. Admar Gonzaga 1346 Florianopolis 88034-000 Brazil Universidade Federal do Parana Rua dos Funcionarios 1540 Curitiba 80035-050 Brazil

The present study aimed to evaluate the effect of thermal processing, press throughput and roller-die gap on pellet physical quality, protein solubility and starch gelatinization in a corn-soybean based broiler diet. The different processing factors were combined in a 2 × 5 × 3 factorial arrangement with eight randomized block consisting of eight production series： two thermal processing treatments （conditioning-pelleting or conditioning-expanding-pelleting）, five press throughput levels （18, 21, 24, 27 and 30 ton/h） and three roller-die gap （0.50, 0.75 and 1.00 mm）, which resulted in 30 different processed feeds. For determination of pellet durability index （PDI）, amount of intact pellets, degree of starch gelatinization and protein solubility, one composed feed sample was collected per treatment in each of eight production series, totaling eight replicates per treatment. Data concerning the amount of intact pellet and protein solubility in KOh were transformed using a variation of Box-Cox transformation in order to fit a normal distribution （P 〉 0.05）. Pellet physical quality was enhanced by conditioning-expanding treatment （P 〈 0.01）, narrower roller-die-gap （P 〈 0.01） and reduced press throughput （P 〈 0.01）. Protein solubility in KOh was impaired （P 〈 0.01） in the expander treatment and larger roller-die distance （0.75 mm and 1.00 mm）（P 〈 0.01）. Finally, greater starch gelatinization degree was achieved in expanded treatment （P 〈 0.01） and in 1.00 mm roller-die gap （P 〈 0.05）. The factors evaluated in this study resulted in interactions and significant effects on physicochemical properties of broiler feed pellets.

关键词： Conditioning expanding press throughput roller-die gap pellet.

Measurement of the Ambient and Extremity Doses in Clinical Oncology hospital, Menoufia University, Egypt

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International Journal of Medical Physics, Clinical Engineering and Radiation Oncology 2018年第2期7卷 248-260页

作者： I. A. El-Mesady G.M. Saleh N. E. khaled A. A. hussein h. M. El-Samman kh. K. Abd-Al Aziz Physics Department Faculty of Science Menoufia University Egypt Clinical Oncology and Nuclear Medicine Department Faculty of Medicine Menoufia University Egypt Ionizing Radiation Department National Institute for Standards Giza Egypt

The ambient dose of radiation therapy and nuclear medicine units of Clinical Oncology hospital, Menoufia University were investigated using thermoluminescence dosimeter MTS-700 and surveymeter (Inspector Radiation Alert). The maximum% difference between read out of both MTS-700 (TLD) and surveymeter did not exceed 6% and 8% for the two hospital units respectively. Values of the annual ambient dose received in both hospital units were found to be incompliant with radiation protection regulations. In addition, the extremity effective dose hp (0.07) of staff in nuclear medicine unit was measured using wrist and finger techniques. Results indicate in-homogenies distribution of fingertips doses. Radiation doses received by the wrists and fingertips of radiopharmaceutical staff preparing 99mTc syringe were observed to be higher by a factor of about 1.41 and 1.44 respectively than those for the administrating staff whom injecting patients by 99mTc syringe, but also still in congruent with international radiation protection regulations.

关键词： Ambient Dose Extremity Dose Thermoluminescence Lithium Fluoride Dosimeter

Usefulness of Impella support in different clinical settings in cardiogenic shock

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Journal of Geriatric Cardiology 2022年第2期19卷 115-124页

作者： María isabel Barrionuevo-Sánchez Albert Ariza-Solé Daniel Ortiz-Berbel JoséGonzález-Costello Joan Antoni Gómez-hospital Victòria Lorente Oriol Alegre Isaac Llaó JoséCarlos Sánchez-Salado Josep Gómez-Lara Arnau Blasco-Lucas Josep Comin-Colet Cardiology Department Intensive Cardiac Care UnitBellvitge University HospitalL’Hospitalet de LlobregatBarcelonaSpain Cardiac Surgery Department Heart Disease InstituteBellvitge University HospitalL’Hospitalet de LlobregatBarcelonaSpain

BACKGROUND The Impella pump has emerged as a promising tool in patients with cardiogenic shock(CS).Despite its attractive properties,there are scarce data on the specific clinical setting and the potential role of Impella devices in CS patients from routine clinical *** This is an observational,retrospective,single center,cohort *** consecutive patients with diagnosis of CS and undergoing support with Impella 2.5?,Impella CP?or Impella 5.0?from April 2015 to December 2020 were *** characteristics,management and outcomes were assessed according to CS severity,age and cause of *** outcome measured was in-hospital *** A total of 50 patients were included(median age:59.3±10 years).The most common cause of CS was acute coronary syndrome(ACS)(68%),followed by decompensation of previous cardiomyopathy(22%).A total of 13 patients(26%)had profound *** patients(54%)improved pulmonary congestion at 48 h after Impella support.A total of 19 patients(38%)presented significant ***-hospital mortality was 42%.Among patients with profound CS(n=13),five patients were previously supported with venoarterial extracorporeal membrane oxygenation.A total of eight patients(61.5%)died during the admission,and no patient achieved ventricular *** patients(≥67 years,n=10)had more comorbidities and the highest mortality(70%).Among patients with ACS(n=34),35.3%of patients had profound CS;and in most cases(52.9%),Impella support was performed as a bridge to *** contrast,only one patient from the decompensated cardiomyopathy group(n=11)presented with profound *** 90.9%of these cases,Impella support was used as a bridge to cardiac *** were no cases of *** In this cohort of real-life CS patients,Impella devices were used in different settings,with different clinical profiles and *** a significant rate of complications,mortality was acceptable and lower than those observed

关键词： Impella clinical routine

CT-Guided Celiac Plexus Neurolysis in the Management of Pain Related to Unresectable Pancreatic Cancer: About 2 Cases

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Open Journal of Gastroenterology 2015年第5期5卷 37-41页

作者： A. Souguir A. hammami kh. Kadri I. Ben Mansour h. Jaziri A. Zayene A. Ben Slama M. Ksiaa A. Brahem S. Ajmi A. Jmaa Department of Gastroenterology Sahloul Sousse Tunisia Department of Radiology Sahloul Sousse Tunisia

Celiac plexus neurolysis (CPN) has become a minimally invasive approach for the management of patients with unresectable pancreatic cancer and abdominal pain unresponsive to medical treatment. CPN has been shown to have long-lasting improvement in abdominal pain and decreased narcotic usage in 70% to 90% of patients. Therefore, the aim of this paper was to report our experience with CPN in the treatment of two cases of advanced pancreatic cancer, with satisfying results in controlling pain. The use of CT scan-guided CPN should be considered and performed relatively early in the course of disease to offer optimal pain relief and increase the patient’s quality of life.

关键词： Pancreas Celiac Plexus Neurolysis Unresectable Pancreatic Cancer Palliative Treatment

在DⅢ—D托卡马克中径向电场在从L模式向h模式向Vh模…

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国外核聚变与等离子体应用 1995年第6期 29-36页

作者： Burr.,kh 甘德昌

在Ｅ×Ｂ漂移速度中，剪切稳定湍流的假设成功地预言了在Ｌ（低）－Ｈ（高）模式转变中观察到的湍流减弱和约束改善；另外，所观察到的Ｅ×Ｂ剪切水平明显超过稳定湍流的理论要求值。而且这一假设是目前的等离子体从Ｈ模式向ＶＨ（甚高... 详细信息

在Ｅ×Ｂ漂移速度中，剪切稳定湍流的假设成功地预言了在Ｌ（低）－Ｈ（高）模式转变中观察到的湍流减弱和约束改善；另外，所观察到的Ｅ×Ｂ剪切水平明显超过稳定湍流的理论要求值。而且这一假设是目前的等离子体从Ｈ模式向ＶＨ（甚高）模式转变时在等离子体芯部观察到的约束进一步改善的最佳解释。因而，目前对Ｈ模式研究的根本问题是：电场Ｅｒ是如何形成的？径向力平衡方程把Ｅｒ与主离子压力梯度△↓ｐｉ。

关键词：径向电场 L-h转变 h-Vh转变托卡马克

红树植物内生真菌Penicillium s p.中一个醌类化学成分的研究

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分析测试学报 2007年第2期26卷 195-197页

作者：李想姚燕华孙光芝郑毅男林文翰 isabel SATTLER 吉林农业大学中药材学院吉林长春130118 北京大学天然药物与仿生药物国家重点实验室北京100083 hans-Knll-Institute for Natural Product Research

利用各种层析手段(反相ODS健合硅胶、葡聚糖凝胶Lh-20柱层析等),从红树植物内生真菌Penicil-liumsp.的发酵液中分离纯化了1个醌类化合物,通过各种波谱实验(1D-NMR,2D-NMR以及ESIMS)确定其结构为:5-甲氧基-11,12,18,19-四羟基蒽醌(1)。

关键词：红树内生真菌 Penicillium sp. 醌类

hypoxia inducible factor-1αaccumulation in steatotic liver preservation:Role of nitric oxide

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World Journal of Gastroenterology 2010年第28期16卷 3499-3509页

作者： Mohamed Amine Zaouali Ismail Ben Mosbah Eleonora Boncompagni hassen Ben Abdennebi Maria Teresa Mitjavila Ramon Bartrons isabel Freitas Antoni Rimola Joan Roselló-Catafau Experimental hepatic Ischemia Reperfusion Unit Institut of Biomedical Research of BarcelonaSpanish National Research Council08036BarcelonaSpain Liver Transplantation and Graft Viability Unit August Pi i Sunyer Biomedical Research Institut08036Barcelona Spain Animal Biology Department Pavia University27100PaviaItaly Laboratory of human Physiology Faculty of PharmacyUniversity of Monastir5000Monastir Tunisia Department of Physiology Faculty of BiologyUniversity of Barcelona08028BarcelonaSpain Physiological Sciences Department Bellvitge CampusInstitut of Biomedical Research of Bellvitge-Barcelona University08907BarcelonaSpain

AIM:To examine the relevance of hypoxia inducible factor(hIF-1)and nitric oxide(NO)on the preservation of fatty liver against cold ischemia-reperfusion injury(IRI). METhODS:We used an isolated perfused rat liver model and we evaluated hIF-1αin steatotic and non-steatotic livers preserved for 24 h at 4℃in University of Wisconsin and IGL-1 solutions,and then subjected to 2 h of normothermic *** normoxic reperfusion,liver enzymes,bile production,bromosulfophthalein clearance,as well as hIF-1αand NO[endothelial NO synthase(eNOS)activity and nitrites/nitrates]were also *** factors associated with the higher susceptibility of steatotic livers to IRI,such as mitochondrial damage and vascular resistance were evaluated. RESULTS:A significant increase in hIF-1αwas found in steatotic and non-steatotic livers preserved in IGL-1 after cold *** preserved in IGL-1 showed a significant attenuation of liver injury and improvement in liver function *** benefits were enhanced by the addition of trimetazidine(an antiischemic drug),which induces NO and eNOS activation, to IGL-1 *** normoxic reperfusion,the presence of NO favors hIF-1αaccumulation,promoting also the activation of other cytoprotective genes,such as hemeoxygenase-1. CONCLUSION:We found evidence for the role of the hIF-1α/NO system in fatty liver preservation,especially when IGL-1 solution is used.

关键词： Fatty liver Tissue preservation hypoxia inducible factor-1α IGL-1 Nitric oxide Trimetazidine

红树植物内生真菌Penicillium sp.中两个甾体化合物的研究

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天然产物研究与开发 2007年第3期19卷 420-422页

作者：李想孙光芝郑毅男林文翰 isabel Sattler 吉林农业大学中药材学院北京大学天然药物与仿生药物国家重点实验室 hans-Knll-Institute for Natural Product Research Beutenbergstraβe 11D-07745JenaGermany

从红树植物内生真菌Penicillium sp.的发酵液中分离纯化了两个甾体类化合物,通过各种波谱实验(1D-NMR,2D-NMR,ESI-MS)确定为:麦角甾-4,6,8(14),22-四烯-3-酮(1)和麦角甾-5,7,22-三烯-3-醇(2),1对于3α-hSD脱氢酶在250μm浓度下有较弱的... 详细信息

从红树植物内生真菌Penicillium sp.的发酵液中分离纯化了两个甾体类化合物,通过各种波谱实验(1D-NMR,2D-NMR,ESI-MS)确定为:麦角甾-4,6,8(14),22-四烯-3-酮(1)和麦角甾-5,7,22-三烯-3-醇(2),1对于3α-hSD脱氢酶在250μm浓度下有较弱的活性。

关键词：红树植物内生真菌 Penicillium sp. 甾体化合物