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Contribution of the Advanced Research Laboratories at the Noguchi Memorial Institute for Medical Research (NMIMR) to SARS-CoV-2 Testing in Ghana

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Health 2022年第1期14卷 125-136页

作者： Darius N. K. Quansah Ivy A. Asante Evelyn Y. Bonney Evangeline Obodai Mildred A. adusei-poku James Aboagye Susan adu-Amankwah Samuel Adjei Richard Akuffo Helena Lamptey George B. Kyei John K. Odoom William K. Ampofo Joseph H. K. Bonney Department of Virology Noguchi Memorial Institute for Medical Research University of Ghana Legon Accra Ghana West African Centre for Cell Biology of Infectious Pathogens College of Basic and Applied Sciences University of Ghana Legon Accra Ghana Department of Medical Microbiology University of Ghana Medical School Accra Ghana Medical and Scientific Research Directorate University of Ghana Medical Centre Legon Accra Ghana Department of Epidemiology Noguchi Memorial Institute for Medical Research University of Ghana Legon Accra Ghana Department of Animal Experimentation Noguchi Memorial Institute for Medical Research University of Ghana Legon Accra Ghana Department of Immunology Noguchi Memorial Institute for Medical Research University of Ghana Legon Accra Ghana

In March 2020, the first cases of SARS-CoV-2 were reported in Accra, Ghana. These initial cases were diagnosed at the Advanced Research Laboratories (ARL) of the Noguchi Memorial Institute for Medical Research (NMIMR), University of Ghana. The ARL which hitherto was used for routine clinical research in viral, bacteria and immunological studies has since been the facility of choice for testing for all suspected cases of COVID-19 submitted from across Ghana and beyond. The success of testing at the ARL hinged on the availability of several laboratory spaces furnished with state-of-the-art diagnostic equipment and working aids. During the “peak season” where overwhelming numbers of clinical specimens were received, the ARL processed and got results for close to four thousand samples daily. After general disinfection and re-bagging into smaller numbers, at the entrance of the ARL, the samples are taken to a central receiving laboratory, where they are received and entered in a database with accompanying case investigation forms. All samples that are successfully sorted and matched are sent to general laboratories for nucleic acid extraction and then referred to the Instrumentation laboratory for real time reverse-transcription polymerase chain reaction (RT-PCR). When the RT-PCRs were completed, results were analysed and transmitted via email and/or local network to the data reporting office. The data managers then reported results to the investigators and the Ghana Health Service (GHS). Additionally, the ARL provided a next-generation Genome Sequencing platform in partnership with the West African Centre for Cell Biology of Infectious Pathogens at the University of Ghana, which was essential in reporting the genome data of the circulating variants of SARS-CoV-2 in Ghana. Conclusively, it is worth noting, that the NMIMR fulfilled its mandate of supporting the country with specialized diagnostics through the judicious use of the ARL for SARS-CoV-2 testing, from sample re

关键词： Advanced Research Laboratories Polymerase Chain Reaction Severe Acute Respiratory Syndrome—Corona Virus 2 Corona Virus Disease 2019

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The Perspectives of Kwame Nkrumah University of Science and Technology Dental School Graduates

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Open Journal of Stomatology 2018年第5期8卷 158-167页

作者： Alex Oti Acheampong Felix Ampofo Anafi Nana Tuffuor Ampem Gyimah Ama Amuasi Solomon Obiri-Yeboah Daniel Kwesi Sabbah Alfred Nyarko Merley Newman Nartey Patrick Ampofo Stephen Ankoh Joseph Abu-Sakyi isaac Kwaku Asiamah Robert Nii Lamy Larmie Francis adu-Ababio James Appiah Amoateng Peter Donkor Kwame Nkrumah University of Science and Technology Dental School Kumasi Ghana Kumasi South Hospital Kumasi Ghana Komfo Anokye Teaching Hospital Oral Health Directorate Kumasi Ghana University of Ghana School of Medicine and Dentistry Accra Ghana

Background: The idea of establishing a Dental school at the Kwame Nkrumah University of Science and Technology (KNUST) was borne out of a need. There was a shortfall in the supply of dental surgeons, especially in the northern half of the country. Aim/Objective: To seek for feedback from KNUST Dental school graduates over the past six about their overall assessment of the BDS courses taught during their clinical training and challenges faced in the course of their training. Methodology: A cross-sectional retrospective study of all KNUST Dental school graduates from 2012 to 2017. A structured goggle form questionnaire was developed. The Google form link was emailed to the representatives who in turn forwarded the link to their year mates. The questionnaire was filled online and submitted as requested. Results: This represented 63.0% of the entire graduates from KNUST Dental School. The male to female ratio was 1.3:1.0. The age range of our graduate was from 24 yrs (3.8%) to 32 years (1.9%). The average age was 26.3 years. 48.10% of respondents said their training was very good. The major challenges were inadequate clinical space (25.2%) and lack of materials and dental chairs for students’ clinic (27.3%). Conclusion: On the whole, the quality of the training was rated as very good even though some of the courses taught during the clinical training were rated as poor. Inadequate dental chairs, laboratory and clinic materials, supervision of student’s clinic were some of the major challenges expressed by the graduates.

关键词： Dentistry Perspective Graduates Challenges Students

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