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Observations from the Working Group Peritoneal Carcinosis

Journal of Cancer Therapy 2022年第8期13卷 507-524页

作者： Manju Domnick Martin Domnick iris ernst Frank P. Müller Viktor Rempel Norman Bitterlich Hüseyin Sahinbas Stefan Könemann Stathis Philippou Praxis and Praxisklinik Domnick Herten Germany German Centre for Stereotaxy and Precision Radiation (DZSP) Soest Germany Catholic Karl Leisner Clinic gGmbH Kleve Germany St. Anna Hospital Herne Herne Germany Medizin & Service GmbH Chemnitz Germany Praxis für Hyperthermie Düsseldorf Germany Radiotherapy Centre Bochum Bochum Germany Institute of Pathology of the Augusta Hospital Bochun Germany

The aim of this report was to describe the feasibility, overall survival and quality of life of combining multimodal therapy with a complementary therapy concept called LOTUS Care Cure program. The peritoneal carcinomatosis (PC) working group described their observations on the combination of multimodal therapy with a complementary therapy concept based on 132 patients with different cancer entities with suspected PC. PC was not confirmed by laparoscopy in 32.5% of the patients included in the working group of patients with suspected PC. Patient compliance and the feasibility were high. For Ki67, there is a cut-off at 45% with a slower progression at 45%. The higher the Karnofsky index, the more improved the therapy and tolerability, with a cut-off of 80%. Overall, 72.0% of patients died. The median survival time in the overall population was 3.74 years (95% CI, 2.57 to 4.91) with a sharp decline in the first 16 weeks. The quality of life of patients can be improved with the implementation of the complementary LOTUS Care Cure Project. Overall, the therapy of PC requires a multi-professional team of therapists and a multimodal therapy concept. The multimodal concept together with the Lotus Care Cure project shows very good feasibility with high compliance and ultimately leads to better and low-risk patient care.

关键词： Multimodal and Complementary Therapy Peritoneal Carcinosis Quality of Life

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How aromatic dissolved organic matter differs in competitiveness against organic micropollutant adsorption

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Environmental Science and Ecotechnology 2024年第5期21卷 92-102页

作者： Qi Wang Oliver JLechtenfeld Luuk CRietveld Jonas Schuster Mathias ernst Roberta Hofman-Caris Jan Kaesler Chunmiao Wang Min Yang Jianwei Yu Frederik Zietzschmann Key Laboratory of Drinking Water Science and Technology Research Center for Eco-Environmental SciencesChinese Academy of Sciences100085BeijingChina Delft University of Technology Department of Water ManagementPO Box 50482600GADelftthe Netherlands Department of Analytical Chemistry Research Group BioGeoOmicsHelmholtz Centre for Environmental ResearchUFZPermoserstr.1504318LeipzigGermany Berliner Wasserbetriebe LaboratoryMotardstr.3513629BerlinGermany Institute for Water Resources and Water Supply Hamburg University of TechnologyAm Schwarzenberg-Campus 321073HamburgGermany KWR Watercycle Research Institute 3433PENieuwegeinthe Netherlands ProVISCentre for Chemical Microscopy Helmholtz Centre for Environmental ResearchUFZPermoserstr.1504318LeipzigGermany Wageningen University and Research Department of Environmental TechnologyBornse Weilanden 96708 WGWageningenthe Netherlands University of Chinese Academy of Sciences 100049BeijingChina

Activated carbon is employed for the adsorption of organic micropollutants(OMPs)from water,typically present in concentrations ranging from ng L1 to mg L***,the efficacy of OMP removal is considerably deteriorated due to competitive adsorption from background dissolved organic matter(DOM),present at substantially higher concentrations in mg L*** the characteristics of competitive DOM is crucial in predicting OMP adsorption efficiencies across diverse natural *** weight(MW),aromaticity,and polarity influence DOM *** the aromaticity-related metrics,such as UV254,of low MW DOM were proposed to correlate with DOM competitiveness,the method suffers from limitations in understanding the interplay of polarity and aromaticity in determining DOM ***,we elucidate the intricate influence of aromaticity and polarity in low MW DOM competition,spanning from a fraction level to a compound level,by employing direct sample injection liquid chromatography coupled with ultrahigh-resolution Fouriertransform ion cyclotron resonance mass *** exchange resin pre-treatment eliminated 93%of UV254-active DOM,predominantly aromatic and polar DOM,and only minimally alleviated DOM *** characterization revealed that nonpolar molecular formulas(constituting 26%PAC-adsorbable DOM)with medium aromaticity contributed more to the DOM *** analysis indicated that the competitiveness of highly aromatic LMW DOM compounds was strongly counterbalanced by increased *** aromaticity-derived p-p interaction cannot facilitate the competitive adsorption of hydrophilic DOM *** results underscore the constraints of depending solely on aromaticity-based approaches as the exclusive interpretive measure for DOM *** a broader context,this study demonstrates an effect-oriented DOM analysis,elucidating counterbalancing interactions of DOM molecular properties

关键词： Activated carbon Organic micropollutants Dissolved organic matter(DOM) Multi-component adsorption Fourier-transform ion cyclotron resonance mass spectrometry(FT-ICR-MS)

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为什么要探索太空（节选）

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疯狂英语(初中天地) 2024年第4期 12-17页

作者： ernst Stuhlinger

1970年，赞比亚修女就给美国国家航空航天局写了一封信：“目前地球上还有这么多小孩子吃不上饭，你们怎么舍得为远在火星的项目花费数十亿美元？”本文节选自美国国家航空航天局的科学家写给她的回信。我相信，致力于太空计划有助于缓...

1970年，赞比亚修女就给美国国家航空航天局写了一封信：“目前地球上还有这么多小孩子吃不上饭，你们怎么舍得为远在火星的项目花费数十亿美元？”本文节选自美国国家航空航天局的科学家写给她的回信。我相信，致力于太空计划有助于缓解乃至最终解决地球上诸如贫困与饥饿这样的严峻问题。饥饿问题的根本在于两个方面：食物生产与食物分配。通过农业、畜牧业、远洋渔业以及其他大规模生产方式进行食物生产在世界某些地区行之有效，但在其他许多地区效率极其低下。

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为什么要探索太空(节选)

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疯狂英语（初中天地） 2024年第4期 11-17页

作者： ernst Stuhlinger 不详

1970年,赞比亚修女就给美国国家航空航天局写了一封信:“目前地球上还有这么多小孩子吃不上饭,你们怎么舍得为远在火星的项目花费数十亿美元?”本文节选自美国国家航空航天局的科学家写给她的回信。

关键词：美国国家航空航天局一封信太空赞比亚科学家

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挖掘应用型高校和双元制教育对不同社会背景人才培养的潜力

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应用型高等教育研究 2024年第2期9卷 40-46页

作者： ernst Deuer 陈颖(翻译) 巴登-符腾堡州拉文斯堡双元制大学德国拉文斯堡88212 奥斯纳布吕克应用科学大学

随着专业人才短缺问题的加剧,亟需在各个层面上更有效地开发和利用潜在受教育群体的学习机会。从教育公平的角度来看,现在比以往任何时候都更需要基于学生的实际表现和潜力来促进不同社会背景群体的发展。在此过程中,高等教育系统,尤其... 详细信息

随着专业人才短缺问题的加剧,亟需在各个层面上更有效地开发和利用潜在受教育群体的学习机会。从教育公平的角度来看,现在比以往任何时候都更需要基于学生的实际表现和潜力来促进不同社会背景群体的发展。在此过程中,高等教育系统,尤其是应用型和双元制教育发挥着重要作用。

关键词：教育资源大学入学教育公平

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CONJUGATE-SYMPLECTICITY OF LINEAR MULTISTEP METHODS

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Journal of Computational Mathematics 2008年第5期26卷 657-659页

作者： ernst Hairer Section de Mathématiques Univ.de Genève

For the numerical treatment of Hamiltonian differential equations, symplectic integrators are the most suitable choice, and methods that are conjugate to a symplectic integrator share the same good long-time behavior. This note characterizes linear multistep methods whose underlying one-step method is conjugate to a symplectic integrator. The bounded- hess of parasitic solution components is not addressed.

关键词： Linear multistep method Underlying one-step method Conjugate-symplecticity,Symmetry.

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Insensitive high explosives:Ⅳ. Nitroguanidine-Initiation & detonation

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Defence Technology（防务技术） 2019年第4期15卷 467-487页

作者： ernst-Christian Koch Lutradyn-Energetic Materials

This paper reviews the detonative properties of low bulk density(LBD),high bulk density(HBD)Nitroguanidine(NGu)(1),CAS-No:[556-88-7]and 82 explosive formulations based on NGu reported in the public *** rank the performance of those formulations they are compared with 15 reference compositions containing both standard high explosives such as octogen(HMX)(2),hexogen(RDX)(3),pentaerythritol tetranitrate(PETN)(4),2,4,6-trinitrotoluene(TNT)(5)as well as insensitive high explosives such as 3-nitro-1,2,4-triazolone(NTO)(6),1,3,5-triamino-2,4,6-trinitrobenzene(TATB)(7),1,1-diamino-2,2-dinitroethylene(FOX-7)(8)and N-Guanylurea dinitramide(FOX 12)(9).NGu based formulations are superior to those based on FOX-12 or TATB and are a close match with FOX-7 based explosives,the latter just having higher Gurney Energies(-10%)and slightly higher detonation pressure(+2%).NGu based explosives even reach up to 78% of the detonation pressure,82% Gurney energy and up to 95% of detonation velocity of ***-NGu dissolves in many melt cast eutectics forming dense charges thereby eliminating the need for costly High Bulk Density *** based formulations are at the rock bottom of sensitiveness among all the above-mentioned explosives which contributes to the safety of these *** review gives 132 references to the public *** a review on the synthesis spectroscopy and sensitiveness of Nitroguanidine see Ref.[1].

关键词： Cook-off Detonation Insensitive munitions Nitroguanidine Shock sensitvity

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Special materials in pyrotechnics Ⅶ: Pyrotechnics used in thermal batteries

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Defence Technology（防务技术） 2019年第3期15卷 254-263页

作者： ernst-Christian Koch Lutradyn Energetic Materials Science & Technology

Thermal batteries are unique direct current(DC) electrical power sources with long shelf live, high reliability and higher power density than classical alkaline batteries. This paper gives a brief overview into the working principle of thermal batteries and reviews the properties of zirconium/barium chromate(Zr/BaCrO4) pyrolant previously used as first fire and iron/potassium perchlorate(Fe/KClO4) pyrolant(Heat), commonly applied as heating pellet in thermal batteries and its hazard properties. The review gives 64 references to the public domain. CAS-Nos. Zr: [7440-67-7], BaCrO4: [10294-40-3], Fe: [7439-89-6], KClO4: [7778-74-7], Viton: [9011-17-0].CAS-Nos. Zr: [7440-67-7], BaCrO4: [10294-40-3], Fe: [7439-89-6], KClO4: [7778-74-7], Viton: [9011-17-0].

关键词： Barium chromate Heat-powder Iron Lithium Molten salt Potassium perchlorate Pyrotechnics Thermal battery Zirconium

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Using coalgebras and the Giry monad for interpreting game logics a tutorial

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Frontiers of Computer Science 2017年第6期11卷 948-970页

作者： ernst-Erich DOBERKAT Math++ Software Bochum 44879 Germany

The stochastic interpretation of Parikh＇s game logic should not follow the usual pattern of Kripke models, which in turn are based on the Kleisli morphisms for the Giry monad, rather, a specific and more general approach to proba- bilistic nondeterminism is required. We outline this approach together with its probabilistic and measure theoretic basis, in- troducing in a leisurely pace the Giry monad and its Kleisli morphisms together with important techniques for manipu- lating them. Proof establishing specific techniques are given, and pointers to the extant literature are provided. After working through this tutorial, the reader should find it easier to follow the original literature in this and related areas, and it should be possible for her or him to appreciate measure theoretic arguments for original work in the areas of Markov transition systems, and stochastic effectivity func- tions.

关键词： coalgebras modal logics monads Giry monad,upper closed monad composition of monads game logics

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Superlubricity on the nanometer scale

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Friction 2014年第2期2卷 106-113页

作者： ernst MEYER Enrico GNECCO Department of Physics University of BaselKlingelbergstr.824056 BaselSwitzerland IMDEA Nanociencia Campus Universitario de CantoblancoCalle Faraday 928049 MadridSpain

The transition from atomic stick-slip to continuous sliding has been observed in a number of *** extended contacts are moved in different directions,so-called structural lubricity is observed when the two surface lattices are ***,a“superlubric”state of motion can be achieved if the normal force is reduced below a certain threshold,the temperature is increased,or the contact is actuated *** processes have been partially demonstrated using atomic force microscopy,and they can be theoretically understood by proper modifications of the Prandtl−Tomlinson model.

关键词： structural lubricity dynamic superlubricity atomic force microscopy friction force microscopy themolubricity Prandtl−Tomlinson model

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