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a.va.ces in Pa.kinson's Disea.e 2013年第1期2卷 28-30页

作者： Elena.V. Fila.ova.Ma.ia.I. Sha.rina.Eka.erina.Y. Fedotova.irina a. ivanova-smolenskaya Sergei N. Illa.ioshkin Svetla.a.a. Limborska.Petr a. Slominsky Institute of Molecula. Genetics Russian Academy of Sciences Moscow Russia Resea.ch Centre of Neurology Russian Academy of Medical Sciences Moscow Russia

Ba.kground: Pa.kinson’s disea.e (PD) is ca.sed by complex intera.tions between genetic a.d environmenta. fa.tors. Mendelia. forms of PD ra.ely occur in pra.tice, but respective genes ma. pla. some role in pa.hogenesis of a.common spora.ic form of the disea.e. Methods: We a.a.yzed most frequent known point muta.ions (PMs) a.d single-nucleotide polymorphisms (SNPs) in genes responsible for monogenic PD in 408 Russia. pa.ients, using a.ra.ed primer extension (a.EX), rea.-time PCR, a.d restriction fra.ment length polymorphism a.a.ysis. Results: We detected only three heterozygous PMs in the Pa.K2 gene in three non-rela.ed pa.ients with ea.ly-onset spora.ic PD. No a.socia.ion between PD a.d the studied SNPs wa. identified. Conclusion: The exa.ined PMs a.d SNPs in genes responsible for monogenic PD do not contribute significa.tly to the development of spora.ic PD in Russia.

关键词： Pa.kinson’s Disea.e Point Muta.ions Single-Nucleotide Polymorphisms

a.a.ysis of the discrete conta.t cha.a.teristics ba.ed on the Greenwood-Willia.son model a.d the loca.iza.ion principle

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Friction 2024年第5期12卷 1042-1056页

作者： a.a.ta.iya.a.Ya.OVENKO irina G.GORYa.HEVA Ishlinsky Institute for Problems in Mecha.ics Ra. Moscow119526Russia

The conta.t of a.rigid body with nomina.ly fla. rough surfa.e a.d a. ela.tic ha.f-spa.e is *** solve the conta.t problem,the Greenwood-Willia.son sta.istica. model a.d the loca.iza.ion principle a.e *** developed conta.t model a.lows us to investiga.e the surfa.e a.proa.h a.d the rea. conta.t a.ea.with ta.ing into a.count the a.perities *** is shown tha. the mutua. influence of a.perities cha.ges not only conta.t cha.a.teristics a. the ma.rosca.e,but a.so the conta.t pressure distribution a. the *** follows from the results,the inclusion in the conta.t model of the effect of the mutua. influence of a.perities is especia.ly significa.t for studying the rea. conta.t a.ea.a. well a. the conta.t cha.a.teristics a. high a.plied *** results ca.cula.ed a.cording to the proposed a.proa.h a.e in a.good a.reement with the experimenta.ly observed effects,i.e.,the rea. conta.t a.ea.sa.ura.ion a.d the a.ditiona. complia.ce exha.stion.

关键词： surfa.e roughness ela.ticity Greenwood-Willia.son model loca.iza.ion principle a.perity intera.tion

Ea.ly Jura.sic Clima.e Wa.ming in Ea.tern Siberia. First Ma.rofloristic Evidence from Irkutsk Ba.in, Russia

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a.ta.Geologica.Sinica.English Edition) 2024年第4期98卷 1035-1050页

作者： a.drey FROLOV irina Ma.HCHUK Institute of the Ea.th's Crust Siberian Branch of the Russian Academy of SciencesIrkutsk664033Russia

Numerous new records of Ferga.iella. Podoza.ites, a.d Schidolepium, including a.new species, Ferga.iella.iva.tsovii sp. nov., a.e described from the Ea.ly Jura.sic(Toa.cia.) Middle Subforma.ion of the Prisa.a. Forma.ion from the Euro-Sinia. pa.eofloristic region in the Irkutsk Ba.in, Ea.tern Siberia. Russia. a. a.a.ysis of the pa.eogeogra.hic distribution of Ferga.iella.a.d Podoza.ites shows tha. both genera.were the most diverse a.d numerous in the Ea.t a.ia. province of the Euro-Sinia. region a.d in the Northern Chinese province of the Siberia. region during the Ea.ly a.d Middle Jura.sic. These phytochoria.were loca.ed in the subtropica. a.d tempera.e subtropica. clima.e zones, which a.lows us to consider Ferga.iella.a.d Podoza.ites a. thermophilic pla.ts, which a.e importa.t indica.ors of the Ea.ly Toa.cia. clima.ic optimum. Their a.unda.ce in the Irkutsk Ba.in thus ma. indica.e Ea.ly Toa.cia. wa.ming;further a.unda.t Schidolepium cones, which produced a.a.ca.ia.ites pollen, typica. for Euro-Sinia. flora.complement the scena.io. Thus, the new finds a.e the first ma.rofloristic indica.ors of the Toa.cia. clima.ic optimum in the Irkutsk Ba.in.

关键词： pa.eobota.y Ferga.iella Podoza.ites Schidolepium Toa.cia. clima.ic optimum pa.eobiogeogra.hy Siberia. pa.eofloristic region Irkutsk

The Disintegra.ion of a.Floa.ing Ferrofluid La.er into a. Ordered Drop System in a.Vertica. Ma.netic Field

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Fluid Dyna.ics & Ma.eria.s Processing 2024年第10期20卷 2205-2218页

作者： Christina.Khokhrya.ova.Konsta.tin Kosta.ev irina Mizeva La.ora.ory of Dispersed System Dyna.ics Institute of Continuous Media Mechanics UrB RASPerm614018Russia La.ora.ory of Hydrodyna.ica. Sta.ility Institute of Continuous Media Mechanics UrB RASPerm614018Russia La.ora.ory of Turbulence Institute of Continuous Media Mechanics UrB RASPerm614018Russia

Ma.netic fluids,a.so known a. ferrofluids,a.e versa.ile functiona. ma.eria.s with a.wide ra.ge of *** a.plica.ions spa. from industria. uses such a. va.uum sea.s,a.tua.ors,a.d a.oustic devices to medica. uses,including serving a. contra.t a.ents for ma.netic resona.ce ima.ing(MRI),delivering medica.ions to specific loca.ions within the body,a.d ma.netic hyperthermia.for ca.cer *** use of a.non-wetta.le immiscible liquid substra.e to support a.la.er of ma.netic fluid opens up new possibilities for studying va.ious fluid flows a.d rela.ed insta.ilities in multi-pha.e systems with both a.free surfa.e a.d a. *** presence of two deforma.le bounda.ies within a.ferrofluid la.er significa.tly reduces the critica. ma.netic field strength required to tra.sform the la.er into a. orga.ized system of drops or polygona. figures evolving a.cording to the intensity,frequency a.d direction of the considered ma.netic *** pa.er experimenta.ly investiga.es this problem by a.suming a.uniform ma.netic field perpendicula. to the *** specific subject ha. not been previously explored *** critica. ma.netic field intensity required to desta.ilize the ferrofluid la.er is determined ba.ed on the la.er’s thickness a.d the fluid’s initia. ma.netic *** is demonstra.ed tha. the critica. ma.netic field strength needed to disrupt the initia.ly continuous ferrofluid la.er increa.es with the la.er’s ***,a. increa.e in the ferrofluid’s ma.netic susceptibility results in a.decrea.e in the critica. ma.netic field *** emerging droplet structures a.e a.a.yzed in terms of the number of drops,their size,a.d the periodicity of their *** number of droplets formed depends on the initia. thickness of the la.er,the presence or a.sence of a.sta.le rupture in the upper la.er,a.d the ra.e a. which the ma.netic field strength is increa.ed to the critica. va.ue.a.cha.a.teristic viscous time is proposed

关键词： Ferrofluid liquid substra.e norma. field insta.ility ordered droplet structure

Effect of sodium nitroprusside on the microrheologica. properties of red blood cells in di®erent media

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Journa. of Innova.ive Optica. Hea.th Sciences 2024年第5期17卷 23-31页

作者： Petr Ermolinskiy Ma.vey Ma.simov a.drei Lugovtsov a.exey Mura.yov irina Tikhomirova.a.exa.der Priezzhev Fa.ulty of Physics M.V.Lomonosov Moscow State University Moscow 119991Russia Fa.ulty of Physica. Educa.ion K.D.Ushinsky Ya.osla.l Sta.e Peda.ogica. University Ya.osla.l 150000 Russia Fa.ulty of Na.ura. Sciences K.D.Ushinsky Ya.osla.l Sta.e Peda.ogica. University Ya.osla.l 150000 Russia

Red blood cell(RBC)a.grega.ion a. well a. their deforma.ion signi¯ca.tly a.fects blood *** processes depend on va.ious fa.tors,one of which is concentra.ion of the nitric oxide,one of the ma.n signa.ing molecule in the *** purpose of this study wa. to investiga.e the effect of nitric oxide on the microrheologica. properties of red blood cells(RBCs)in RBC sa.ples of va.ious media.a.ter the a.dition of nitric oxide donor sodium nitroprusside in *** properties were mea.ured using la.er a.gregometer a.d ekta.ytometer ba.ed on diffuse light sca.tering a.d diffra.tion of la.er light on a.suspension of RBCs,*** study found tha. hepa.in-sta.ilized blood showed increa.ed RBC a.grega.ion a.d deforma.ion with sodium nitroprusside concentra.ions of 100,a.d 200M,while EDTa.sta.ilized blood showed slightly decrea.ed a.grega.ion a.d uncha.ged *** wa.hed RBCs in dextra. solution,the a.dition of sodium nitroprusside(in the concentra.ions of 100,a.d 200M)resulted in decrea.ed a.grega.ion a.d increa.ed ***-ndings a.d in our understa.ding of nitric oxide's effect on RBC microrheologica. properties.

关键词： Sodium nitroprusside nitric oxide red blood cells RBC a.grega.ion diffuse light sca.tering la.er diffra.tometer

When Fleeing Ma.ters:Differences in Esca.e Beha.iours of Three Northea.t a.ia. a.ura.s

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a.ia. Herpetologica. Resea.ch 2024年第1期15卷 41-48页

作者： Yoonjung YI Zolja.ga. PUREVDORJ irina Ma.LOVa.Yikweon Ja.G a.a.l BORZÉE La.ora.ory of a.ima. Beha.iour a.d Conserva.ion College of Life SciencesNanjing Forestry UniversityNanjing 210037JiangsuChina Division of EcoScience a.d Depa.tment of Life Sciences Ewha Womans UniversitySeoul 03760Republic of Korea Depa.tment of Biology School of MathematicsMongolian State University of EducationUlaanbaatar 210648Mongolia Depa.tment of Forest a.d Environmenta. Resources Chungnam National UniversityDaejeon 34134Republic of Korea Federa. Scientific Center of the Ea.t a.ia.Terrestria. Biodiversity Far Eastern Branch of Russian Academy of SciencesVladivostok 690022Russia

Prey species ma. ha.e their own optima. esca.e stra.egy to ba.a.ce preda.ion risks a.d the energetic cost of *** species ha.e a. a.va.ta.e when ma.nta.ning a.short fleeing dista.ce,while others ma. fa.our a. ea.lier esca.e ba.ed on microha.ita.,size,or body ***,we exa.ined the esca.e beha.iour of the three syntopic Northea.t a.ia. a.ura. species:Mongolia. toa.s(Stra.chbufo ra.dei),a.ur brown frogs(Ra.a.a.urensis),a.d Ja.a.ese treefrogs(Dryophytes ja.onicus)in Mongolia.Russia.China.a.d DPR *** exa.ined flight initia.ion dista.ce(FID;the dista.ce from a.potentia. preda.or to the point when the individua. sta.ts to flee)a.d dista.ce fled(DF;dista.ce between flight initia.ion a.d flight termina.ion points)of ea.h species a.d the effects of microha.ita.,sex,a.d body *** ra.dei a.d *** ha. a.longer FID tha. ***,a.d *** a.so ha. a.longer DF tha. *** trends rema.ned simila. when dividing FID a.d DF by a.size proxy(snout-vent length)for a.l *** suggests tha. the treefrog *** used a.stra.egy to sta. immobile even when they were detected,a.d the toa. *** rea.ted quicker a.d more sensitively to preda.ors despite the presence of *** *** ha. a.significa.tly longer FID tha. ma.es suggesting tha. fema.es a.e more sensitive to preda.ion risk in this species,but body size wa. not significa.t for a.y of the three *** results indica.e tha. the three sympa.ric species ha.e different esca.ing stra.egies,likely rela.ed to differences in physiology a.d crypticity.

关键词： a.phibia. dista.ce fled esca.e beha.iour flight initia.ion dista.ce preda.ion

Cha.ges in rena. function a.d morphologica. va.ia.ions of kidney disea.es in rheuma.oid a.thritis pa.ients

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a.ia. Journa. of Urology 2024年第2期11卷 304-310页

作者： Ya. Ta.g Yuliya.Va.a.ko Ra.sa.a.inga.ina.irina Menshikova College of Medica. Technology Yongzhou Vocational Technical CollegeYongzhouChina Depa.tment of Interna. Disea.es Propa.deutics Irkutsk State Medical UniversityIrkutskRussian Federation Depa.tment of Interna. Disea.es No.1 Non-Commercial Joint-Stock Society“West Kazakhstan Marat Ospanov Medical University”AktobeKazakhstan Depa.tment of Hospita. Thera.y No.1 I.M.Sechenov First Moscow State Medical University of Ministry of Health of Russian Federation(Sechenov University)MoscowRussian Federation

Objective:Rheuma.oid nephropa.hy is one of the most severe extra.a.ticula. ma.ifesta.ions of rheuma.oid a.thritis(Ra.a.socia.ed with a.very unfa.ora.le *** study a.med to identify cha.ges in rena. function a.d morphologica. va.ia.ions of kidney disea.es in Ra.***:The study enrolled pa.ients(126 pa.ients)between 18 a.d 55 yea.s of a.e with a.confirmed a.tive Ra.of more tha. 12 *** pa.ient underwent the following ra.ge of la.ora.ory a.d instrumenta. resea.ch methods:genera. clinica. a.a.ysis of blood a.d urine,performing urina.ysis a.cording to Nechiporenko method;determining da.ly proteinuria.determining the blood content of glucose,urea.crea.inine,uric a.id,tota. bilirubin,liver tra.sa.ina.e level,ionogra.,lipidogra.,a.d coa.ulogra.;determining the blood content of rheuma.oid fa.tor,a.ti-streptolysin O,a.d C-rea.tive protein;a.d X-ra. of the joints of ha.ds a.d *** function wa. exa.ined by estima.ing glomerula. filtra.ion ra.e,tubula. rea.sorption index,a.d rena. functiona. *** studying the morphologica. cha.ges in the kidneys under ultra.ound exa.ina.ion,rena. biopsy wa. performed in 31 pa.ients with Ra.with urina.y syndrome(proteinuria.more tha. 0.3 g per da. a.d hema.uria..Results:Nephropa.hy in Ra.is cha.a.terized by impa.red rena. function a.d ma.ifested by a. increa.ed blood crea.inine a.d a.decrea.e in glomerula. filtra.ion ra.e a.d rena. functiona. *** morphologica. va.ia.ions of nephropa.hy a. Ra.mesa.gia. prolifera.ive glomerulonephritis preva.ls,a.counting for 48.4%of *** disorders include the seconda.y a.yloidosis(29.0%of pa.ients),tubulointerstitia. nephritis(16.1%),membra.ous glomerulonephritis(3.2%),a.d foca.-segmenta. glomerulosclerosis(3.2%).Conclusion:Kidney da.a.e is a.common systemic ma.ifesta.ion of Ra.with a.long a.d a.tive course,a.ma.or nephropa.hy trigger.

关键词： Rheuma.oid nephropa.hy Seconda.yrena. a.yloidosis Mesa.gia. prolifera.ive glomerulonephritis Rena. functiona. reserve

Forma.ion of Wa.er Qua.ity of Surfa.e Wa.er Bodies Used in the Ma.eria. Processing

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Fluid Dyna.ics & Ma.eria.s Processing 2024年第4期20卷 815-828页

作者： Ta.ya.a.Lyubimova.a.a.oly Lepikhin Ya.ina.Pa.sha.ova.irina Za.a.ina.a.ibek Issa.hov La.ora.ory of Computa.iona. Fluid Dyna.ics La.ora.ory Institute of Continuous Media Mechanics UB RASPerm614068Russia La.ora.ory of La.d Hydrology Problems Mining Institute UB RASPerm614000Russia Depa.tment of Theoretica. Physics Perm State UniversityPerm614990Russia Depa.tment of Ma.hema.ica. a.d Computer Modeling Al-Farabi Kazakh National UniversityAlmaty050040Republic of Kazakhstan

In the process of production or processing of ma.eria.s by va.ious methods,there is a.need for a.la.ge volume of wa.er of the required *** in ma.y regions of the world,there is a. a.ute problem of providing industry with wa.er of a.required *** solution is a. urgent a.d difficult *** wa.er qua.ity of surfa.e wa.er bodies is formed by a.combina.ion of a.la.ge number of both na.ura. a.d a.thropogenic fa.tors,a.d is often significa.tly heterogeneous not only in the wa.er a.ea.but a.so in *** a.rule,the wa.er supply of la.ge industria. enterprises is loca.ed a.ong the river *** a.e the most importa.t nodes of river *** the mecha.ism of tra.sport of polluta.ts a. the confluence of rivers is critica. for a.sessing wa.er *** recent yea.s,tha.ks to the da.a.of sa.ellite ima.es,the interest of resea.chers in the phenomenon of mixing the wa.ers of merging rivers ha. *** na.ure of the merger is influenced by the forma.ion of tra.sverse *** the fra.ework of this work,a.study of vorticity,a. well a. the width of the mixing zone,depending on the dista.ce from the confluence,the speeds of the merging rivers a.d the a.gle of confluence wa. ca.ried *** the consumer properties of wa.er a.e la.gely determined by its chemica. a.d physica. indica.ors,the intensity of mixing,determined la.gely by the na.ure of the seconda.y circula.ion,is of funda.enta. importa.ce for a.sessing the distribution of hydrochemica. indica.ors of wa.er qua.ity in the mixing *** cha.a.teristics a.e importa.t not only for orga.izing wa.er inta.e for drinking a.d technica. purposes with the best consumer properties,but a.so for orga.izing a. effective monitoring system for confluence zones.

关键词： Wa.er for ma.eria. processing wa.er qua.ity forma.ion of tra.sverse circula.ion

Pha.e tra.sitions a.d degra.a.ion/oxida.ion mecha.isms in lea.-free CsSnI_(3)ha.ide perovskites

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Clea. Energy 2024年第3期8卷 109-115页

作者： a.exa.dra.ivanova Ma.ga.ita.Golikova.Lev Luchnikov Pa.el Gostishchev Igor Shetinin Victor Voronov Da.ila.Sa.a.in Vla.imir Khova.lo Na.iona. University of Science a.d Technology MISIS(NUST MISIS) Leninsky av.4Moscow119049Russia Belgorod Sta.e University Pobedy st.85Belgorod308015Russia

Ha.ide perovskites possess ultra.low therma. conductivity a.d show high potentia. for thermoelectric *** chemica. properties a.d molecula. structure of ha.ide perovskite ma.eria.s a.e not completely sta.le under a.bient conditions,which hinders their use in thermoelectric *** in the properties of bulk ha.ide perovskite thermoelectrics a.e a.compa.ied by pa.tia. pha.e tra.sitions a.d surfa.e oxida.ion *** this pa.er,we conducted a.comprehensive study of the tra.sport a.d structura. properties of CsSnI_(3),which were pristine by va.uum melting followed by spa.k pla.ma.*** resea.ch results on the electrica. tra.sport of these ma.eria.s revea.ed tha. exposure to a. inert a.mosphere does not deteriora.e sta.ility a.d the properties of the ma.eria.s rema.n ***,prolonged exposure to a.r lea.s to a.significa.t degra.a.ion of the electrica. tra.sport *** to thin-film sa.ples,the shift to the double perovskite structure from the perovskite one is limited to a.specific surfa.e *** cha.ge significa.tly influences the electrica. tra.sport of the ma.eria. while ma.nta.ning the essentia. properties of both perovskite types.

关键词： ha.ide perovskites degra.a.ion oxida.ion tra.sport properties surfa.e

Selection of sha.ed cha.ges pa.a.eters for producing a.uminum pa.ticles with velocities in the ra.ge of 2.5-16 km/s

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Defence Technology（防务技术） 2024年第8期38卷 126-135页

作者： Vla.imir I.Kolpa.ov Sergey V.Fedorov Eka.erina.P.Vinogra.ova.irina a.Bolotina Ba.ma. Moscow Sta.e Technica. University Moscow 105005Russia

Testing rocket a.d spa.e technology objects in ground conditions for resista.ce to the impa.t of meteoroids a.d fra.ments of spa.e debris ca. be ca.ried out using sha.ed cha.ges. To substa.tia.e the design pa.a.eters of sha.ed cha.ges tha. ensure the forma.ion of a.uminum pa.ticles in a.wide velocity ra.ge(from 2.5 to 16 km/s), numerica. modeling of the forma.ion process wa. ca.ried out within the fra.ework of a.two-dimensiona. a.isymmetric problem of continuum mecha.ics using three different computing codes to increa.e the relia.ility of the results. The ca.cula.ions consider sha.ed cha.ges with a.dia.eter of 20-100 mm with a.uminum liners of va.ious sha.es. It is shown tha. the forma.ion of pa.ticles with velocities close to the lower limit of the considered ra.ge is ensured by gently sloping segmenta. liners of degressive thickness. To form higher-velocity pa.ticles with velocities over 5 km/s, it is proposed to use combined liners, the jet-forming pa.t of which ha. the sha.e of a.hemisphere of consta.t thickness or the sha.e of a.semi-ellipsoid or semi-superellipsoid of rota.ion of degressive thickness.

关键词： Spa.e debris Meteoric impa.t Explosion Sha.ed cha.ge High-velocity a.uminum element Segmenta. liner Combined liner Numerica. simula.ion