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Is intra-operative cholangiography necessary during laparoscopic cholecystectomy? A multicentre rural experience from a developing world country

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World Journal of Gastroenterology 2007年第33期13卷 4493-4497页

作者： iqbal saleem mir mir Mohsin Omar Kirmani Tafazul Majid Khurshid Wani Mehmood-ul Hassan Javed Naqshbandi Mohammed Maqbool Minimal Access Surgery Unit Government Gousia Hospital Khanyar Kashmir 190010 India Department of Radiology Government Gousia Hospital Khanyar Kashmir 190010 India Anaesthesia Unit Government Gousia Hospital Khanyar Kashmir 190010 India

AIM: To evaluate the feasibility and safety of performing laparoscopic cholecystectomy (LC) in nonteaching rural hospitals of a developing country without intra-operative cholangiography (IOC). To evaluate the possibility of reduction of costs and hospital stay for patients undergoing ***: A prospective analysis of patients with symptomatic benign diseases of gall bladder undergoing LC in three non-teaching rural hospitals of Kashmir Valley from Jan 2001 to Jan 2007. The cohort represented a sample of patients requiring LC, aged 13 to 78 (mean 47.2) years. Main outcome parameters included mortality, complications, re-operation, conversion to open procedure without resorting to IOC, reduction in costs borne by the hospital, and the duration of hospital ***: Twelve hundred and sixty-seven patients (976 females/291 males) underwent laparoscopic cholecystectomy. Twenty-three cases were converted to open procedures; 12 patients developed port site infection, nobody died because of the procedure. One patient had common bile duct (CBD) injury, 4 patients had biliary leak, and 4 patients had subcutaneous emphysema. One cholecystohepatic duct was detected and managed intraoperatively, 1 patient had retained CBD stones, while 1 patient had retained cystic duct stones. Incidental gallbladder malignancy was detected in 2 cases. No long-term complications were detected up to ***: LC can be performed safely even in non-teaching rural hospitals of a developing country provided proper equipment is available and the surgeons and other team members are well trained in the procedure. It is stressed that IOC is not essential to prevent biliary tract injuries and missed CBD stones. The costs to the patient and the hospital can be minimized by using reusable instruments, intracorporeal sutures, and condoms instead of titanium clips and endobags.

关键词： Laparoscopic cholecystectomy Intraoperative cholangiography

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An Experience of Short-Term Results of Laparoscopic Inguinal Hernioplasty Using 3D Mesh in a Developing Country

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International Journal of Clinical Medicine 2015年第1期6卷 64-69页

作者： iqbal saleem mir Alfer Ah Nafae Aijaz Ahmed Malyar Muntakhab Nafae Yawar Watali Mudasir Farooq Shahnawaz Bashir Bhat Sheikh Viqar The Post-Graduate Department of Surgery Govt Medical College Srinagar India

Background: The experience of short term results of laparoscopic inguinal hernia repair using 3D mesh in a developing country is reviewed. Methods: From January 2012 to February 2014, 53 patients underwent laparoscopic inguinal hernioplasty. A retrospective case series of 53 consecutive patients undergoing TEP/TAPP by a single surgical team was followed prospectively with a focused physical examination and interview. 4 out of 53 patients had recurrent hernia following open repairs and 49 had primary hernias. Data collected included operative time, intraoperative bleeding, intraoperative difficulties, immediate postoperative pain, chronic groin pain, recurrence, sensory disturbance, activity or occupational limitation and personal satisfaction. Results: All the patients were male aged 32 to 75 years with a mean age of 53.5 years. Mean operative time was 37.4 minutes;intraoperative dissection, blood loss were less;and immediate postoperative pain was negligible as assessed by VAS. There was no mortality or major morbidity. Mean follow-up was 12 months (2 to 18 months). Follow-up was completed by interview and physical examination. Hernia was not found to recur during the follow up period. Chronic pain occurred in 2 patients (3.7%), which was mild in nature. Ninety-seven percent of patients were satisfied with their repair and would or had recommended TEP/TAPP to others using 3D Mesh. Conclusions: Short-term results of TEP/TAPP hernia repair using 3D mesh demonstrated to be an effective and safe procedure with low prevalence of chronic pain that is generally of a mild, infrequent nature. It was also concurred that there is decrease in operative time. Manipulation of mesh was significantly reduced. Intraoperative bleeding and use of post operative analgesia was reduced considerably. There was no recurrence, however the cost of the mesh increased the overall cost of the procedure acting as a limiting factor in a developing country.

关键词： Inguinal Hernia 3D Prolene Mesh Totally Extra-Peritoneally (TEP) Trans-Abdominal Pre-Peritoneal (TAPP)

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Hyperinsulinemia,cancer and maqui berry:The promise of nutritional supplementation

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Food Science and Human Wellness 2019年第3期8卷 264-267页

作者： Brett Deters mir saleem Halmos College of Natural Sciences and Oceanography NOVA Southeastern UniversityFort LauderdaleFL 33314USA

Nutritional supplementation has long been studied as a possible treatment alternative or as an adjunct to the standard treatments for common ailments and *** to the latest research,the Chilean maqui berry,Aristotelia chilensis,has been shown to reduce postprandial insulin levels by as much as fifty *** berry,which has been shown to be as effective as metformin at increasing insulin sensitivity and controlling blood glucose levels,follows a simple mechanism of action that involves the inhibition of sodium dependent glucose transporters in the small intestine,slowing the rate at which sugars enter the bloodstream and thereby decreasing blood sugar spikes and the corresponding increase in insulin *** high blood glucose levels have been proven to play a significant role in the development of cancers,as diabetics and prediabetics have been proven to have elevated risk of developing cancerous *** dietary supplementation with maqui berry may therefore indirectly reduce the risk of cancer,as well as other diseases which respond negatively to hyperglycemia and hyperinsulinemia.

关键词： Hyperinsulinemia Cardiovascular disease Diabetes Insulin Maqui berry Cancer

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The role of glutamine in supporting gut health and neuropsychiatric factors

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Food Science and Human Wellness 2021年第2期10卷 149-154页

作者： Brett J.Deters mir saleem Halmos College of Natural Sciences and Oceanography NOVA Southeastern UniversityFort LauderdaleFL 33314 USA

Recent research has shown that the amino acid glutamine can positively affect gut health by supporting the gut microbiome,gut mucosal wall integrity,and by modulating infiammatory *** modulated by the vagus nerve,via the enteric nervous system,the gut-brain connection can impact the brain’s neurochemical *** gut health can disrupt the balance of neurotransmitters,which can result in neuropsychiatric based conditions such as *** supplementation may provide significant adjunctive nutritional support in cases of depression by promoting proper gut health and function.

关键词： Glutamine Gut Neuropsychiatry Enteric nervous system Neurotransmitters Microbiome

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The importance of preventative medicine in conjunction with modern day genetic studies

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Genes & Diseases 2018年第2期5卷 107-111页

作者： Sierra Sandler Lauren Alfino mir saleem NOVA Southeastern University United States

Genetic screening in the primary care setting is the future of preventative *** testing is an important medical tool for assessing various inheritable diseases,conditions,and *** ability to diagnose patients before symptoms surface can help lessen the severity of symptoms and promote quality of ***,genetic screening can cause psychological distress from the knowledge of test results,in some cases only serving to increase the risk of developing a condition due to *** testing can be conducted anytime in life,even before *** this review,a compilation of genetic testing’s definitions and boundaries,factors influencing an individual’s test outcomes,and an overview of a wide variety of diseases,conditions and cancers were collected.

关键词： Cancer screening DNA testing Genetic abnormalities Genetic analysis Gene mutation Hereditary disorders Prevention of genetic diseases Primary care

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Visual News Ticker Surveillance Approach from Arabic Broadcast Streams

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Computers, Materials & Continua 2023年第3期74卷 6177-6193页

作者： Moeen Tayyab Ayyaz Hussain Usama mir M.Aqeel iqbal Muhammad Haneef Department of Computer Science and Software Engineering International Islamic UniversityIslamabad44000Pakistan Department of Computer Science Quaid-i-Azam UniversityIslamabad44000Pakistan Department of Computer Science Senior Member IEEEUniversity of WindsorN9B 3P4Canada Department of Software Engineering Foundation University IslamabadIslamabad44000Pakistan Department of Electrical Engineering Foundation University IslamabadIslamabad44000Pakistan

The news ticker is a common feature of many different news networks that display headlines and other *** ticker recognition applications are highly valuable in e-business and news surveillance for media regulatory *** this paper,we focus on the automatic Arabic Ticker Recognition system for the Al-Ekhbariya news *** primary emphasis of this research is on ticker recognition methods and storage *** that end,the research is aimed at character-wise explicit segmentation using a semantic segmentation technique and words identification *** proposed learning architecture considers the grouping of homogeneousshaped *** incorporates linguistic taxonomy in a unified manner to address the imbalance in data distribution which leads to individual ***,experiments with a novel ArabicNews Ticker(Al-ENT)dataset that provides accurate character-level and character components-level labeling to evaluate the effectiveness of the suggested *** proposed method attains 96.5%,outperforming the current state-of-the-art technique by 8.5%.The study reveals that our strategy improves the performance of lowrepresentation correlated character classes.

关键词： Arabic text recognition optical character recognition deep convolutional network SegNet LeNet

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A Novel Edge-Assisted IoT-ML-Based Smart Healthcare Framework for COVID-19

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Computer Modeling in Engineering & Sciences 2023年第12期137卷 2529-2565页

作者： Mahmood Hussain mir Sanjay Jamwal Ummer iqbal Abolfazl Mehbodniya Julian Webber Umar Hafiz Khan Department of Computer Sciences Baba Ghulam Shah Badshah UniversityRajouriJammu&KashmirIndia Department of Computer Sciences National Institute of Electronics and Information TechnologySrinagarJammu&KashmirIndia Department of Electronics and Communication Engineering Kuwait College of Science and TechnologyKuwait City20185145Kuwait Department of Geriatric Medicine Sher-i-Kashmir Institute of Medical SciencesSrinagarJammu&KashmirIndia

The lack of modern technology in healthcare has led to the death of thousands of lives worldwide due to COVID-19 since its *** Internet of Things(IoT)along with other technologies like Machine Learning can revolutionize the traditional healthcare *** of reactive healthcare systems,IoT technology combined with machine learning and edge computing can deliver proactive and preventive healthcare *** this study,a novel healthcare edge-assisted framework has been proposed to detect and prognosticate the COVID-19 suspects in the initial phases to stop the transmission of coronavirus *** proposed framework is based on edge computing to provide personalized healthcare facilities with minimal latency,short response time,and optimal energy *** this paper,the COVID-19 primary novel dataset has been used for experimental purposes employing various classification-based machine learning *** proposed models were validated using kcross-validation to ensure the consistency of *** on the experimental results,our proposed models have recorded good accuracies with highest of 97.767%by Support Vector *** to the findings of experiments,the proposed conceptual model will aid in the early detection and prediction of COVID-19 suspects,as well as continuous monitoring of the patient in order to provide emergency care in case of medical volatile situation.

关键词： COVID-19 edge computing framework Internet of Things(IoT) machine learning(ML) network symptoms

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Anti-hypercholesterolemic and anti-hyperglycaemic effects of conventional and supercritical extracts of black cumin(Nigella sativa)

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Asian Pacific Journal of Tropical Biomedicine 2017年第11期7卷 1014-1022页

作者： Muhammad Jawad iqbal Masood Sadiq Butt mir Muhammad Nasir Qayyum Hafiz Ansar Rasul Suleria National Institute of Food Science and Technology Faculty of FoodNutrition and Home SciencesUniversity of AgricultureFaisalabadPakistan Department of Agriculture and Food Technology Karakoram International UniversityGilgit-BaltistanPakistan UQ Diamantina Institute Translational Research InstituteFaculty of MedicineThe University of Queensland37 Kent Street WoolloongabbaBrisbaneQLD 4102Australia Department of Food NutritionDietetics and HealthKansas State UniversityManhattanKS 66506USA

Objective: To explore the hypoglycaemic and hypocholesterolemic potential of conventional and supercritical extracts of black ***: Purposely, rat modelling was carried out for 2 months by designing three studies i.e. study Ⅰ(normal rats), study Ⅱ(hyperglycaemic rats) and study Ⅲ(hypercholesterolemic rats). Each study was further divided into three groups based on diet ***, functional diet(contained extract of black cumin prepared by using conventional solvent) and nutraceutical diet(contained extract of black cumin prepared by supercritical fluid extraction system).Results: During whole trial, an abating trend was observed in the level of serum cholesterol with maximum reduction(12.8%) in nutraceutical group of study Ⅲ. Low density lipoprotein and triglyceride level was also lowered maximum in study Ⅲ as17.1% and 11.6%, respectively. Whereas, highest decline in glucose level was in nutraceutical group of study Ⅱ as 11.2%.Conclusions: Inclusion of black cumin extracts in diet significantly lowers the occurrence of hyperglycaemia and hypercholesterolaemia. Furthermore, hypoglycaemic and hypocholesterolemic potential of nutraceutical diet is more prominent as compared to functional diet.

关键词： Black cumin Functional food Nutraceuticals Supercritical extract Hyperglycaemia Hypercholesterolaemia

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The BV Formalization of Chern-Simons Theory on Deformed Superspace

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Communications in Theoretical Physics 2012年第11期58卷 704-710页

作者： mir Faizal Mathematical Institute University of OxfordOxford OX1 3LBEngland

In this paper we will study non-abelian Chern-Simons theory on a deformed superspace. We will deform the superspace in such a way that it includes the noncommutativity between bosonic and fermionic coordinates. We will first analyse the BRST and the anti-BRST symmetries of the Chern-Simons theory on this deformed superspace. Then we will analyse the extended BRST and the extended anti-BRST symmetries of this theory in the Batalin-Vilkovisky (BV) formalism. Finally, we will express these extended BRST and extended anti-BRST symmetries in extended superspace formalism by introducing new Grassmann coordinates.

关键词： noncommutative superspace Batalin-Vilkovisky formalism

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Vault RNAs(vtRNAs):Rediscovered non-coding RNAs with diverse physiological and pathological activities

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Genes & Diseases 2024年第2期11卷 772-787页

作者： Mahsa Aghajani mir Deputy of Research and Technology Health Research InstituteBabol University of Medical SciencesBabol 47176-4774Iran

The physicochemical characteristics of RNA admit non-coding RNAs to perform a different range of biological acts through various mechanisms and are involved in regulating a diversity of fundamental ***,some reports of pathological conditions have proved abnormal expression of many non-coding RNAs guides the *** RNAs are a class of non-coding RNAs containing stem regions or loops with well-conserved sequence patterns that play a fundamental role in the function of vault particles through RNA-ligand,RNA–RNA,or RNA-protein *** together,vault RNAs have been proposed to be involved in a variety of functions such as cell proliferation,nucleocytoplasmic transport,intracellular detoxification processes,multidrug resistance,apoptosis,and autophagy,and serve as microRNA precursors and signaling *** decades of investigations devoted,the biological function of the vault particle or the vault RNAs is not yet completely *** this review,the current scientific assertions of the vital vault RNAs functions were discussed.

关键词： ncRNA Vault complex Vault RNA vtRNA viral infection tumorigenesis

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