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Bulletin of the Chinese Academy of Sciences 2020年第2期34卷 74-77页

作者：无 Wing-Huen ip BCAS the International Space Science Institute

***-Huen ip,a world-renown scientist in cometary physics,planetary science,solar system evolution and exoplanets,took the post of the Executive Director of the International Space Science Institute一Beijing(ISSI-BJ)in *** the only partner of the well-known International Space Science Institute(ISSI)in Bern outside Switzerland,ISSI-BJ has adopted the same tools as ISSI to facilitate international cooperation and academic exchanges:workshops,forums,and others that rely on in-person communications.

关键词： Director planet outside

Non-linear dynamic state-space network modeling for decoding neurodegeneration

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Neural Regeneration Research 2024年第9期19卷 1879-1880页

作者： Venkata C.Chirumamilla Chi Wang ip Martin Reich Robert Peach Jens Volkmann Bahman Nasseroleslami Muthuraman Muthuraman Prenatal Pediatrics Institute Children’s National HospitalWashingtonDCUSA Neural Engineering with Signal Analytics and Artificial Intelligence Department of NeurologyUniversity of WürzburgWürzburgGermany Academic Unit of Neurology Trinity Biomedical Sciences InstituteTrinity College DublinUniversity of DublinDublinIreland

Neurodegenerative disorders represent a pervasive global health challenge,yet therapeutic options remain conspicuously *** disorders are inherently dynamic processes within the central nervous system,unfolding across distinct sub-stages:initial structural neuronal alterations(sub-stage 1),functional impairment(sub-stage 2),and culminating in neuronal death(sub-stage 3).

关键词： alterations impairment dynamic

Comparing 11 early warning scores and three shock indices in early sepsis prediction in the emergency department

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World Journal of Emergency Medicine 2024年第4期15卷 273-282页

作者： Rex Pui Kin Lam Zonglin Dai Eric Ho Yin Lau Carrie Yuen Ting ip Ho Ching Chan Lingyun Zhao Tat ChiTsang Matthew Sik Hon Tsui Timothy Hudson Rainer Department of Emergency Medicine School of Clinical MedicineLi Ka Shing Faculty of Medicinethe University of Hong KongHong KongChina School of Public Health Li Ka Shing Faculty of Medicinethe University of Hong KongHong KongChina Accident and Emergency Department Queen Mary HospitalHong KongChina

BACKGROUND:This study aimed to evaluate the discriminatory performance of 11 vital sign-based early warning scores(EWSs)and three shock indices in early sepsis prediction in the emergency department(ED).METHODS:We performed a retrospective study on consecutive adult patients with an infection over 3 months in a public ED in Hong *** primary outcome was sepsis(Sepsis-3 definition)within 48 h of ED *** c-statistics and the DeLong test,we compared 11 EWSs,including the National Early Warning Score 2(NEWS2),Modified Early Warning Score,and Worthing Physiological Scoring System(WPS),etc.,and three shock indices(the shock index[SI],modified shock index[MSI],and diastolic shock index[DSI]),with Systemic Inflammatory Response Syndrome(SIRS)and quick Sequential Organ Failure Assessment(qSOFA)in predicting the primary outcome,intensive care unit admission,and mortality at different time ***:We analyzed 601 patients,of whom 166(27.6%)developed ***2 had the highest point estimate(area under the receiver operating characteristic curve[AUROC]0.75,95%CI 0.70-0.79)and was significantly better than SIRS,qSOFA,other EWSs and shock indices,except WPS,at predicting the primary ***,the pooled sensitivity and specificity of NEWS2≥5 for the prediction of sepsis were 0.45(95%CI 0.37-0.52)and 0.88(95%CI 0.85-0.91),*** discriminatory performance of all EWSs and shock indices declined when used to predict mortality at a more remote time ***:NEWS2 compared favorably with other EWSs and shock indices in early sepsis prediction but its low sensitivity at the usual cut-off point requires further modification for sepsis screening.

关键词： Sepsis Emergency department Clinical prediction rule Early warning score Shock index

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《ip电话网关设备技术要求》简介

电信技术 2000年第10期 53-53页

作者： ip与多媒体标准研究组

Delivering a high-quality colonoscopy service fit for the 21st century

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Artificial Intelligence in Gastrointestinal Endoscopy 2024年第3期5卷 1-8页

作者： Brian Wing Kin ip Daniel Jin Keat Lee Kok Yang Tan Department of General Surgery Khoo Teck Puat HospitalSingapore 768828Singapore Department of Surgery Khoo Teck Puat HospitalSingapore 768828Singapore

Colorectal cancer(CRC)is the third most prevalent cancer *** is a concerning increase in its incidence among younger *** remains the gold standard for CRC *** the introduction of population-based bowel screening and increased public awareness,there has been a significant rise in referrals for *** providers worldwide will need to strategically evaluate how to allocate resources to adequately train the next generation of colonoscopists who will need to provide accurate endoscopic assessment and treatment for premalignant polyps and early *** review outlines the current workload challenges faced by colonoscopists whilst exploring emerging technologies such as artificial intelligence for adenoma ***,advanced endoscopic surgical techniques like endoscopic submucosal dissection are discussed.

关键词： Colonoscopy Colorectal cancer Bowel screening Polyps Adenoma

Prostate health index can stratify patients with Prostate Imaging Reporting and Data System score 3 lesions on magnetic resonance imaging to reduce prostate biopsies

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Asian Journal of Andrology 2024年第1期26卷 20-24页

作者： John Shung-Lai Leung Wai-Kit Ma Brian Sze-Ho Ho Stacia Tsun-Tsun Chun Rong Na Yongle Zhan Chi-Yuen Ng Chi-Ho ip Ada Tsui-Lin Ng Yiu-Chung Lam Division of Urology Department of SurgeryQueen Mary HospitalUniversity of Hong KongHong KongChina Division of Urology Department of SurgeryPrincess Margaret HospitalHongKongChina

We aim to evaluate prostate health index as an additional risk-stratification tool in patients with Prostate Imaging Reporting and Data System score 3 lesions on multiparametric magnetic resonance *** with biochemical or clinical suspicion of having prostate cancer who underwent multiparametric magnetic resonance imaging in two tertiary centers(Queen Mary Hospital and Princess Margaret Hospital,Hong Kong,China)between January 2017 and June 2022 were ***-magnetic resonance imaging fusion biopsies were performed after prostate health index *** who only had Prostate Imaging Reporting and Data System score 3 lesions were further stratified into four prostate health index risk groups and the cancer detection rates were *** of the 747 patients,47.3%had Prostate Imaging Reporting and Data System score 3 lesions *** detection rate of clinically significant prostate cancer in this group was 15.0%.The cancer detection rates of clinically significant prostate cancer had statistically significant differences:5.3%in prostate health index<25.0,7.4%in prostate health index 25.0-34.9,17.9%in prostate health index 35.0-54.9,and 52.6%in prostate health index≥55.0(P<0.01).Among the patients,26.9%could have avoided a biopsy with a prostate health index<25.0,at the expense of a 5.3%risk of missing clinically significant prostate *** health index could be used as an additional risk stratification tool for patients with Prostate Imaging Reporting and Data System score 3 *** could be avoided in patients with low prostate health index,with a small risk of missing clinically significant prostate cancer.

关键词： biopsy fusion biopsy magnetic resonance imaging prostate cancer prostate health index

Neurovascular ageing:transcriptomic readout and implications on therapeutic targeting in Alzheimer’s disease

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Neural Regeneration Research 2021年第12期16卷 2411-2412页

作者： Zhongqi Li Bonaventure ip Vincent C.T.Mok Ho Ko Division of Neurology Department of Medicine and TherapeuticsThe Chinese University of Hong KongHong Kong Special Administrative RegionChina Li Ka Shing Institute of Health Sciences The Chinese University of Hong KongHong Kong Special Administrative RegionChina(Li ZKo H)Margaret K.L.Cheung Research Centre for Management of ParkinsonismThe Chinese University of Hong KongHong Kong Special Administrative RegionChina Chow Yuk Ho Technology Centre for Innovative Medicine The Chinese University of Hong KongHong Kong Special Administrative RegionChina Gerald Choa Neuroscience Centre School of Biomedical SciencesDepartment of PsychiatryPeter Hung Pain Research InstituteFaculty of MedicineThe Chinese University of Hong KongHong Kong Special Administrative RegionChina

Ageing is one of the greatest risk factors for neurodegenerative *** the complex biological changes in ageing increase the brain’s susceptibility to neurodegeneration remains incompletely *** into neurodegenerative disorders has shifted from a neuron-centric approach,to the contributing roles of age-related neurovascular and glial cell dysfunction.

关键词： incomplete susceptibility ageing

A study of the global magnetic activity of the star Kepler-17 using light curve inversion with bipartite regularization

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Research in Astronomy and Astrophysics 2021年第4期21卷 173-192页

作者： Tao Luo Yan-Yan Liang Wing-Huen ip Hao-Zhi Huang Xu-Xin Lin State Key Laboratory of Lunar and Planetary Sciences Macao University of Science and TechnologyMacaoChina Faculty of Information Technology Macao University of Science and TechnologyMacaoChina Institute of Astronomy “National Central University”ZhongliTaoyuan

A new method of light curve inversion with bipartite regularization(LIBR),which is complementary to the previous treatments by Bonomo and Lanza and Estrela and Valio,is used to reconstruct the physical properties of star spots on the solar-type star Kepler-17 by using the full Q1-Q17 data *** Markov Chain Monte Carlo(MCMC)method was applied to find the best profile of the reconstructed *** known value of the rotation inclination of Kepler-17 allows the generation of a star spot model in a sequence of stellar rotation with a period of 12.26 *** of the nature of the light curve inversion,the spot model is limited to the equatorial *** also investigated the starspot lifetimes of Kepler-17 utilizing the MCMC *** with the LIBR inversion results,it was found that the star spots typically last from one to several stellar *** the time evolution of the spot size,a magnetic cycle period of 437 d can be *** value is comparatively shorter than the solar cycle which might be a consequence of the younger age(~1.78 Gyr)of *** light curve of Kepler-17 is characterized by the presence of large-amplitude variation caused by star spots but no superflare *** interesting possibility is that the magnetic energy stored in the star spot regions could have been constantly dissipated by electrodynamic interaction between the central star and the hot Jupiter,Kepler-17 b,via a lower-level energy release process.

关键词： stars:activity stars:imaging stars:spots

Clinical profile and outcomes in very elderly patients with atrial fibrillation anticoagulated with rivaroxaban: data from the EMIR study

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Journal of Geriatric Cardiology 2024年第7期21卷 723-732页

作者： Francisco Marín Manuel Anguita Sánchez Iñaki Lekuona Marcelo Sanmartín Fernán-dez Vivencio Barrios Carlos Perez Muñoz Juan Cosín-Sales Alejandro ipérez Cabeza Vanesa Roldán Schilling Carles Rafols Priu Esteban Orenes-Piñero María Asunción Es-teve-Pastor Department of Cardiology Hospital Clínico Universitario Virgen de la ArrixacaIMIB-ArrixacaUniversity of MurciaCIBERCVMurciaSpain Department of Cardiology Hospital Reina Sofía CórdobaIMIBICUniversity of CordobaCIBERCVCórdobaSpain Hospital Galdakao-Usansolo BizkaiaSpain Department of Cardiology Hospital Uni-versitario Ramony CajalCIBERCVMadridSpain Department of Cardiology University Hospital Ramóny CajalAl-caláUniversityMadridSpain Medical Center La Capillita Sanlúcar de Barrameda.Private cardiology clinicJerez de la FronteraSpain Department of Cardiology Hospital Arnau de VilanovaValenciaSpain Department of Car-diology Virgen de la Victoria University HospitalCIBERCV.MalagaSpain Department of Haematology Hospital Clínico Universitario Virgen de la ArrixacaUniversity of MurciaMurciaSpain Department of Medical Affairs Bayer HispaniaBarcelonaSpain Department of Biochemistry and Molecular Biology-A University of MurciaMurciaSpain

Objectives To analyze the clinical profile,adequacy of treatment with rivaroxaban and outcomes in octogenarians with atrial fibrillation(AF),taking rivaroxaban in clinical *** Observational and non-interventional study that included AF adults recruited from 79 Spanish centers,anticoagulated with rivaroxaban ≥ 6 months before being *** were analyzed according to age(≥ 80 vs.iplatelet agents and non-severe dementia were independently associated with the development of ischemic stroke,whereas previous coronary revascularization and heart failure with MACE,and higher HAS-BLED score with major *** In clinical practice,around one third of patients taking rivaroxaban are *** patients have many comorbidities and a high thromboembolic *** that,rates of adverse events remain *** is adequately prescribed in the majority of octogenarians.

关键词： patients atrial bleeding

回归25周年澳门地区高等教育的成就——以私立非牟利高校为例

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中国高教研究 2024年第10期 72-77页

作者：叶桂平胡波陈红澳门城市大学中国澳门999078 澳门科技大学国际学院中国澳门999078 澳门城市大学葡语国家研究院中国澳门999078

澳门地区回归25周年以来,高等教育取得了显著成就,其中6所私立非牟利高校功不可没。目前,澳门地区私立非牟利高校教学规模扩张成效显著,教学质量持续提升,科研产出成果丰硕,国际化水平逐步提高,国际排名不断攀升,服务澳门地区及区域发... 详细信息

澳门地区回归25周年以来,高等教育取得了显著成就,其中6所私立非牟利高校功不可没。目前,澳门地区私立非牟利高校教学规模扩张成效显著,教学质量持续提升,科研产出成果丰硕,国际化水平逐步提高,国际排名不断攀升,服务澳门地区及区域发展颇具实效。私立非牟利高校的成就是澳门地区高等教育发展的缩影,其成功关键在于“一国两制”下教育治理的有效实践。澳门地区私立非牟利高校充分利用特区的制度优势,不断推动高等教育质量提升,创造了私立高等教育发展史上的奇迹。

关键词：澳门地区高等教育私立非牟利高校回归25周年教育成就 “一国两制”