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Pediatric surgery during the COVID-19 pandemic

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World Journal of Clinical Pediatrics 2020年第2期9卷 7-16页

作者： Aikaterini Dedeilia Stepan M Esagian ioannis A Ziogas Dimitrios Giannis ioannis Katsaros GeorgiosTsoulfas Surgery Working Group Society of Junior DoctorsAthens 15123Greece National and Kapodistrian University of Athens Athens 15772Greece Department of Surgery Division of Hepatobiliary Surgery and Liver TransplantationVanderbilt University Medical CenterNashvilleTN 37232United States Institute of Health Innovations and Outcomes Research the Feinstein Institute forΜedical ResearchManhassetNY 11030United States Department of Surgery Metaxa Cancer HospitalPiraeus 18537Greece First Department of Surgery Aristotle University of ThessalonikiThessaloniki 54622Greece

The coronavirus disease 2019(COVID-19)pandemic has had a major impact on pediatric *** infection is often asymptomatic and atypical in children,while overlapping presentations with other infectious diseases generate additional diagnostic *** high probability of missed pediatric cases and the invasive nature of surgery generate great concern for widespread transmission in this *** guidelines suggest that triage of cases should be made on a case-by-case basis by a multidisciplinary team of *** can be assisted by classifying cases as elective,urgent,or an emergency according to the risks of delaying their surgical management.A workflow diagram should ideally guide the management of all cases from admission to *** surgery is necessary,all staff should use appropriate personal protective equipment,and high-risk practices,such as aerosol-generating tools or procedures,should be avoided if ***,carefully designed organizational protocols should be established to minimize transmission while ensuring the uninterrupted operation of pediatric surgery *** example,surgical teams can be divided into small weekly rotating groups,and healthcare workers should be continuously monitored for COVID-19 ***,team protocols in the operating room can optimize communication and improve adherence to personal protective equipment *** operating rooms,pediatric intensive care units,and surgical wards should be specifically designed for suspected or confirmed COVID-19 ***,transportation of patients should be minimal and follow designated short *** these measures can help mitigate the effects of the COVID-19 pandemic on pediatric surgery units.

关键词： Pediatric surgery COVID-19 SARS-CoV-2 Coronavirus Emergency surgery Personal protective equipment

An Interview with Peter Deadman—Acupuncture Pioneer and Founder of The Journal of Chinese Medicine

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Chinese Medicine and Culture 2024年第1期7卷 19-28页

作者： ioannis Solos Charles Buck Peter Deadman Saint George Clinic and Research Institute Scottsdale 85251the United States of America Northern College of Acupuncture Micklegate YO16LJthe United Kingdom British Acupuncture Council London W129HQthe United Kingdom The Register of Chinese Herbal Medicine London WC1N 3GSthe United Kingdom

This interview was conducted on August 21st, 2022 by Charles Buck and ioannis Solos. Peter Deadman has worked in the field of health promotion for 50 years. He co-founded Infinity Foods(an organic and natural foods workers co-op) in 1971, followed by the Brighton Natural Health Centre-a charity dedicated to teaching ways to improve personal, community and planetary health and wellbeing. He qualified as an acupuncturist in 1978 and in Chinese herbal medicine in 1990. He founded The Journal of Chinese Medicine(UK) in 1979(Fig. 1), and co-authored A Manual of Acupuncture(published in 1998). He is the author of Live Well Live Long: Teachings from the Chinese Nourishment of Life Tradition. He has taught Chinese medicine and health promotion internationally for decades and is a dedicated practitioner and teacher of Qi Gong(气功).

关键词： Acupuncture Medicine herbal

Surgical treatment of hepatic metastases from colorectal cancer

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World Journal of Gastrointestinal Oncology 2011年第1期3卷 1-9页

作者： Georgios Tsoulfas Manousos Georgios Pramateftakis ioannis Kanellos Department of Surgery Aristoteleion University of ThessalonikiThessaloniki 54622Greece

Colorectal carcinoma is one of the most frequent cancers in Western societies with an incidence of around 700 per million *** half of the patients develop metastases from the primary tumor and liver is the primary metastatic *** survival rates after hepatectomy for metastatic colorectal cancer have been reported in the last few years and these may be the result of a variety of factors,such as advances in systemic chemotherapy,radiographic imaging techniques that permit more accurate determination of the extent and location of the metastatic burden,local ablation methods,and in surgical techniques of hepatic *** have led to a more aggressive approach towards liver metastatic disease,resulting in longer *** goal of this paper is to review the role of various forms of surgery in the treatment of hepatic metastases from colorectal cancer.

关键词： Hepatic metastases Colorectal cancer Liver resection

Commentary on:“Human umbilical cord Wharton’s jelly-derived mesenchymal stem cell transplantation could improve diabetic intracavernosal pressure”

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Asian Journal of Andrology 2022年第2期24卷 226-227页

作者： Fotios Dimitriadis Vasileios Palapelas Athanasios Zachariou ioannis Sokolakis Department of Urology Aristotle UniversitySchool of MedicineThessalonikiGreece 3^(rd)Department of Obstetrics and Gynecology Aristotle UniversitySchool of MedicineThessalonikiGreece Department of Urology Ioannina UniversitySchool of MedicineIoanninaGreece Department of Urology Martha-Maria Hospital NurembergNurembergGermany

The article by Wu et al.1 is an interesting and meticulous work investigating the role of human umbilical cord Wharton’s jelly-derived mesenchymal stem cells(hWJ-MSCs)in the treatment of erectile dysfunction(ED)in th... 详细信息

关键词： diabetic al jelly

Management of obstructed colorectal carcinoma in an emergency setting:An update

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World Journal of Gastrointestinal Oncology 2024年第3期16卷 598-613页

作者： Efstathios T Pavlidis ioannis N Galanis Theodoros E Pavlidis 2nd Propedeutic Department of Surgery Hippokration General HospitalSchool of MedicineAristotle University of ThessalonikiThessaloniki 54642Greece

Colorectal carcinoma is common,particularly on the left *** 20%of patients,obstruction and ileus may be the first clinical manifestations of a carcinoma that has advanced(stage II,III or even IV).Diagnosis is based on clinical presentation,plain abdominal radiogram,computed tomography(CT),CT colonography and positron emission tomography/*** best management strategy in terms of short-term operative or interventional and long-term oncological outcomes re-mains *** the most common left-sided obstruction,the first choice should be either emergency surgery or endoscopic decompression by self-expen-dable metal stents or *** operative plan should be either one-stage or two-stage ***-stage resection with on-table bowel decompression and irrigation can be accompanied or not accompanied by proximal defunctioning stoma(colostomy or ileostomy).Primary anastomosis is more convenient but has increased risks of anastomotic leakage and ***-stage resection(Hart-mann’s procedure)is safer and the most widely used despite temporally affecting quality of *** control surgery in high-risk frail patients is less frequently performed since it can be successfully substituted with endoscopic stenting or *** the less common right-sided obstruction,one-stage surgical resection is more beneficial than endoscopic *** role of minimally invasive surgery(laparoscopic or robotic)is a subject of *** laparoscopic-assisted management is advantageous to some extent but requires much expertise due to inherent difficulties in dissecting the distended colon and the risk of rup-ture and subsequent septic *** decompressing stent as a bridge to elective surgery more substantially decreases the risks of morbidity and mortality than emergency surgery for decompression and has equivalent medium-term overall survival and disease-free survival *** combination with neoadjuvant chemotherapy or radiation may have a p

关键词： Acute abdomen Obstructive ileus Colorectal carcinoma Emergency surgery Colectomy Intraluminal metal stents

The effects of implantable collamer lens implantation on higher order aberrations

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International Journal of Ophthalmology(English edition) 2019年第12期12卷 1848-1852页

作者： Belma Kayhan Efekan Coskunseven Onurcan Sahin ioannis Pallikaris Dunyagoz Hospital Group Istanbul 34337Turkey Department of Ophthalmology Sultan Abdulhamid Han Training and Research Hospitalthe University of Saglik BilimleriIstanbul 34668Turkey Institute of Vision and Optics University of CreteHeraklion 70013Greece

AIM: To evaluate the changes in higher order aberrations(HOAs) after implantable collamer lens(ICL;Staar Surgical, Nidau, Switzerland) implantation. METHODS: Totally 30 eyes of 18 patients with myopia were included in this study with an average age of 25.77y(min: 21, max: 40). Refraction, uncorrected distance visual acuity(UDVA), corrected distance visual acuity(CDVA), HOAs(entire, corneal and internal) were evaluated preoperatively and three months postoperatively. Ocular aberrations were measured by using iT race(Tracey Technology, Houston, Texas, USA). SPSS(IBM Corp. Released 2013. IBM SPSS Statistics for Windows, Version 22.0. Armonk, NY: IBM Corp) was used for the statistical analysis and the interpretation of the data. P values of less than 0.05 were considered statistically significant. RESULTS: The preoperative mean spherical power was -9.01 D(min:-5.00, max:-13.00) and the mean cylindrical error was -2.40 D(min:-0.50, max:-4.75). The postoperative mean residual spherical power was -0.73 D(min:-0.20, max:-1.75) and the mean cylindrical error was -0.89 D(min:-0.18, max:-2.09). Analyses were made on root mean square(RMS) values of total HOAs(tH OAs), spherical aberration, coma and trefoil as entire, corneal and internal components. The differences in entire t HOAs and in internal t HOAs were significant. There was no significant change found in spherical aberrations. The differences in entire coma and in internal coma were significant. There was no significant change found in corneal coma. With respect to trefoil, the only significant difference was in internal trefoil. CONCLUSION: The ICL implantation corrects the refractive error successfully and changes entire and internal HOAs of the eye.

关键词： implantable collamer lens myopia aberrations

A Conversation with Professor Ted Kaptchuk,a Key Architect of Modern TCM in the West

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Chinese Medicine and Culture 2024年第1期7卷 5-18页

作者： ioannis Solos Charles Buck Ted Kaptchuk Saint George Clinic and Research Institute Scottsdale 85251the United States of America Northern College of Acupuncture Micklegate YO16LJthe United Kingdom Harvard Medical School Boston 02115the United States of America

The interview was conducted on November 20th,2022 by ioannis Solos and Charles *** Kaptchuk(泰开阳)is a Professor of Medicine and a Professor of Global Health&Social Medicine at Harvard Medical *** 1975,he graduated from the Macao Institute of Chinese Medicine,Macao,*** returning to the West,Ted taught Chinese medicine throughout the States,Europe,Latin America,and ***’s book,The Web that Has No Weaver:Understanding Chinese Medicine is a groundbreaking explanation of East Asian medicine that continues to shape the discourse of the Chinese medicine profession in the West and has been translated into 13 *** 1990,Ted was recruited in Harvard Medical School to help research Chinese *** encountering high placebo responses in multiple acupuncture clinical trials,Ted decided to switch his career to primarily studying *** has published over 300 peer-reviewed *** has been awarded the Lifetime Achievement Award from the Society of Acupuncture Research(2015),the Lifetime Achievement Award from the Society for Interdisciplinary Placebo Studies(2021),and the William Silen Lifetime Achievement Award in Mentoring from Harvard Medical School(2022).

关键词： Acupuncture acupuncture TCM

Critical considerations for the management of gastrointestinal mixed neuroendocrine non-neuroendocrine neoplasms and pure neuroendocrine carcinomas

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World Journal of Gastrointestinal Oncology 2024年第12期16卷 4559-4564页

作者： Efstathios T Pavlidis ioannis N Galanis Theodoros E Pavlidis The 2^(nd)Department of Propaedeutic Surgery Hippokration General HospitalSchool of MedicineAristotle University of ThessalonikiThessaloniki 54642Greece

Mixed neuroendocrine non-neuroendocrine neoplasms constitute rare tumors that are located mainly in the gastrointestinal(GI)tract and have high degrees of malignancy,and the frequency of these tumors has been *** consist of a neuroendocrine neoplastic component with another component of adenocarcinoma usually and have a dismal *** rare GI pure neuroendocrine carcinoma is highly aggressive and requires complex and extensive management since a genetic distinction exists between it and GI non-neuroendocrine neoplasms,which are generally slow-growing *** most common GI-mixed neuroendocrine non-neuroendocrine neoplasms are colorectal,followed by gastric,mainly in the gastroesophageal *** imaging modalities of nuclear medicine and radiology play important roles in the accuracy of *** biopsy may contribute to early detection and timely ***,either endoscopic or abdominal,is a technique that contributes to a diagnosis;additionally,contrast-enhanced ultrasonography is very helpful in followup *** establishes a definite diagnosis and stage by evaluating the cell differentiation grade and the cell proliferation index *** genetic profile can be valuable in diagnosis and gene *** resection with wide lymphadenectomy,whenever possible,and adjuvant chemotherapy constitute the main therapeutic management *** therapy and immunotherapy achieve encouraging results.

关键词： Neuroendocrine neoplasms Gastrointestinal neuroendocrine neoplasms Mixed gastrointestinal neuroendocrine neoplasms Gastrointestinal neuroendocrine carcinomas Neuroendocrine carcinoma Neuroendocrine non-neuroendocrine neoplasms

Minimally invasive pelvic exenteration for primary or recurrent locally advanced rectal cancer:A glimpse into the future

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World Journal of Gastrointestinal Surgery 2024年第7期16卷 1960-1964页

作者： Dimitrios Kehagias Charalampos Lampropoulos ioannis Kehagias Department of General Surgery General University Hospital of PatrasPatras 26504Greece Intensive Care Unit Saint Andrew’s General HospitalPatras 26335Greece Division of Bariatric and Metabolic Surgery Department of SurgeryUniversity of PatrasPatras 26504Greece

Surgeons have grappled with the treatment of recurrent and T4b locally advanced rectal cancer(LARC)for many *** main objectives are to increase the overall survival and quality of life of the patients and to mitigate postoperative ***,pelvic exenteration(PE)with or without neoadjuvant treatment is a curative treatment when negative resection margins are *** traditional open approach has been favored by many ***,the technological advancements in minimally invasive surgery have radically changed the surgical *** studies have demonstrated promising results in postoperative complications and oncological outcomes after robotic or laparoscopic PE.A recent retrospective study entitled“Feasibility and safety of minimally invasive multivisceral resection for T4b rectal cancer:A 9-year review”was published in the World Journal of Gastrointestinal *** we read this article with great interest,we decided to delve into the latest data regarding the benefits and risks of minimally invasive PE for ***,the small number of suitable patients,limited surgeon experience,and steep learning curve are hindering the establishment of minimally invasive PE.

关键词： Locally advanced rectal cancer Pelvic exenteration Multivisceral resection Minimally invasive surgical procedures Robotic surgical procedures