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Athletes with mild post-COVID-19 symptoms experience increased respiratory and metabolic demands:А cross-sectional study

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Sports Medicine and Health Science 2023年第2期5卷 106-111页

作者： Vasileios T.Stavrou Astara Kyriaki george D.Vavougios ioannis g.fatouros george S.Metsios Konstantinos Kalabakas Dimitrios Karagiannis Zoe Daniil Konstantinos I.gourgoulianis george Вasdekis Laboratory of Cardio-Pulmonary Testing and Pulmonary Rehabilitation Respiratory Medicine DepartmentFaculty of MedicineUniversity of ThessalyLarissaGreece The Medical Project PreventionEvaluation and Recovery CenterLarissaGreece Department of Neurology 417 Army Equity Fund Hospital(NIMTS)AthensGreece Department of Neurology Faculty of MedicineUniversity of CyprusLefkosiaCyprus School of Physical Education and Sport Sciences University of ThessalyTrikalaGreece Department of Nutrition and Dietetics University of ThessalyTrikalaGreece

Coronavirus Disease 2019(COVID-19)has significantly affected different physiological systems,with a potentially profound effect on athletic ***,to date,such an effect has been neither addressed nor ***,the aim of this study was to investigate fitness indicators,along with the respiratory and metabolic profile,in post-COVID-19 *** male soccer players,were divided into two groups:non-hospitalized COVID-19(n=20,Age:[25.2±4.1]years,Body Surface Area[BSA]:[1.9±0.2]m^(2),body fat:11.8%±3.4%)versus[vs]healthy(n=20,Age:[25.1±4.4]years,BSA:[2.0±0.3]m^(2),body fat:10.8%±4.5%).For each athlete,prior to cardiopulmonary exercise testing(CPET),body composition,spirometry,and lactate blood levels,were *** between groups were assessed with the independent samples t-test(pgroups:ventilation(:Resting:[14.7±3.1]L·min^(−1)vs.[11.5±2.6]L·min^(−1),p=0.001;Maximal Effort:[137.1±15.5]L·min^(−1)vs.[109.1±18.4]L·min^(−1),pg:7.9%±1.8%vs.5.7%±1.7%,pg:7.9%±2.0%vs.5.9%±1.4%,p=0.001;Maximal Effort:73.7%±11.1%vs.66.2%±9.2%,p=0.026),heart rate(Maximal Effort:[191.6±7.8]bpm vs.[196.6±8.6]bpm,p=0.041),and lactate acid(Resting:[1.8±0.8]mmol·L^(−1)vs.[0.9±0.1]mmol·L^(−1),pg *** significant differences were identified regarding maximal oxygen uptake([55.7±4.4]ml·min^(−1)·kg−1 vs.[55.4±4.6]ml·min^(−1)·kg−1,p=0.831).Our findings demonstrate a pattern of compromised respiratory function in post-COVID-19 athletes characterized by increased respiratory work at both rest and maximum effort as well as hyperventilation during exercise,which may explain the reported increased metabolic needs.

关键词： Cardiopulmonary exercise testing Infected with COVID-19 Respiratory work

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genetic and epigenetic risks of intracytoplasmic sperm injection method

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Asian Journal of Andrology 2006年第6期8卷 643-673页

作者： ioannis georgiou Maria Syrrou Nicolaos Pardalidis Konstantinos Karakitsios Themis Mantzavinos Nikolaos giotitsas Dimitrios Loutradis Fotis Dimitriadis Motoaki Saito Ikuo Miyagawa Pavlos Tzoumis Anastasios Sylakos Nikolaos Kanakas Theodoros Moustakareas Dimitrios Baltogiannis Stavros Touloupides Dimitrios giannakis Michael fatouros Nikolaos Sofikitis Laboratory of Molecular Urology and genetics of Human Reproduction Department of Urology loannina University School of Medicine loannina 45110 Greece Cytogenetics Unit Laboratory of General Biology Medical School University of loannina loannina 45110 Greece Department of Urology Tottori University School of Medicine Yonago 683 Japan Department of Molecular Pharmacology Tottori University School of Medicine Yonago 683 Japan

Pregnancies achieved by assisted reproduction technologies, particularly by intracytoplasmic sperm injection （ICSI） procedures, are susceptible to genetic risks inherent to the male population treated with ICSI and additional risks inherent to this innovative procedure. The documented, as well as the theoretical, risks are discussed in the present review study. These risks mainly represent thatconsequences of the genetic abnormalities underlying male subfertility （or infertility） and might become stimulators for the development of novel approaches and applications in the treatment of infertility. In addition, risks with a polygenic background appearing at birth as congenital anomalies and other theoretical or stochastic risks are discussed. Recent data suggest that assisted reproductive technology might also affect epigenetic characteristics of the male gamete, the female gamete, or might have an impact on early embryogenesis. It might be also associated with an increased risk for genomic imprinting abnormalities.

关键词： genetic risks epigenetic risks intracytoplasmic sperm injection testis male infertility

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