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The Land- Potential Knowledge System (LandPKS): mobile apps and collaboration for optimizing climate change investments

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Ecosystem Health and Sustainability 2016年第3期2卷 31-38页

作者： Jeffrey E.Herrick Adam Beh Edmundo Barrios ioana bouvier Marina Coetzee David Dent Emile Elias Tomislav Hengl Jason W.Karl Hanspeter Liniger John Matuszak Jason CNeff Lilian Wangui Ndungu Michael Obersteiner Keith D.Shepherd Kevin C.Urama Rik van den Bosch Nicholas P.Webb U.S.Department of Agriculture-Agricultural Research Service New Mexico State UniversityJornada Experimental Range MSC 3JERBox 30003Las CrucesNew Mexico 88003-8003 USA World Agroforestry Centre United Nations AvenueGigiriP.O.Box 30677Nairobi00100Kenya U.S.Agency for International Development 3014th StreetSW SA-44(Rm 848)WashingtonD.C.20024 USA Namibia University of Science and Technology 13 Storch StreetPrivate Bag 13388WindhoekNamibia Merchants of Light Ltd Forncett EndNorfolkEngland ISRIC-World Soil information Droevendaalsesteeg 36708PB WageningenThe Netherlands Center for the development and Environment University of BernHallerstrasse 103012BernSwitzerland U.S.Department of State/OES 2201 C St.NWWashingtonD.C.20520USA Environmental Studies Program University of Colorado at BoulderCampus Box 397BoulderColorado 80309 USA RCMRD SERVIR-Eastern&Southern AfricaP.O.Box 63200618 RuarakaNairobiKenya International Institute for Applied Systems Analysis Schlossplatz 1 A-2361LaxenburgAustria African Development Bank Avenue Jean-Paul II01 BP 1387Abidjan 01Côte d’Ivoire

Massive investments in climate change mitigation and adaptation are projected during coming *** of these investments will seek to modify how land is *** return on both types of investments can be increased through an understanding of land potential:the potential of the land to support primary production and ecosystem services,and its resilience.A Land-Potential Knowledge System(LandPKS)is being developed and implemented to provide individual users with point-based estimates of land potential based on the integration of simple,geo-tagged user inputs with cloud-based information and *** system will rely on mobile phones for knowledge and information exchange,and use cloud computing to integrate,interpret,and access relevant knowledge and information,including local knowledge about land with similar *** system will initially provide management options based on long-term land potential,which depends on climate,to-pography,and relatively static soil properties,such as soil texture,depth,and *** mod-ules will provide more specific management information based on the status of relatively dynamic soil properties such as organic matter and nutrient content,and of *** paper includes a discus-sion of how this system can be used to help distinguish between meteorological and edaphic drought.

关键词： agriculture analytics crowdsourcing expert systems extension knowledge management land evaluation land-use planning mobile apps sustainability sustainable land management

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Trends in incidence and management of cancer of the ampulla of Vater

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World Journal of Gastroenterology 2014年第29期20卷 10144-10150页

作者： Florian Rostain Samia Hamza Antoine Drouillard Jean Faivre Anne-Marie bouvier C?me Lepage Registre Bourguignon des Cancers Digestifs INSERM U866CHU de DijonFaculté de Médecine21079 Dijon CedexFrance

AIM: To provide trends in incidence, management and survival of cancer of the ampulla of Vater in a well-defined French population.

关键词： Cancer of the ampulla of Vater Incidence Survival Treatment Epidemiology

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Combined evaluation of biomarkers as predictor of maintained remission in Crohn's disease

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World Journal of Gastroenterology 2019年第19期25卷 2354-2364页

作者： Elisa Sollelis Régine Minet Quinard Guillaume Bouguen Marion Goutte Félix Goutorbe Damien bouvier Bruno Pereira Gilles Bommelaer Anthony Buisson Inserm 3i HP CHU Clermont-Ferrand Service d’Hépato-Gastro Entérologie Université Clermont Auvergne Inserm U1071 M2i SH USC-INRA 2018 Université Clermont Auvergne Biochemistry laboratory University Hospital G.Montpied CHU Rennes Univ Rennes INSERM CIC1414 Institut NUMECAN (Nutrition Metabolisms and Cancer) Gastroenterology Department Hospital of Bayonne Biostatistics Unit DRCI University Hospital

BACKGROUND The individual performances and the complementarity of Crohn's disease(CD)activity index(CDAI), C-reactive protein(CRP) and faecal calprotectin(Fcal) to monitor patients with CD remain poorly inves-tigated in the era of "tight control"and "treat to target" *** To assess CDAI, CRP and Fcal variation, alone or combined, after 12 wk(W12) of anti-tumor necrosis factor(TNF) therapy to predict corticosteroids-free remission(CFREM = CDAI 150 and either CRP >2.9 mg/L or Fcal > 250 μg/g were prospectively *** Among the 40 included patients, 13 patients(32.5%) achieved CFREM at W52. In univariable analysis, CDAI < 150 at W12(P = 0.012), CRP level < 2.9 mg/L at W12(P = 0.001) and Fcal improvement at W12(Fcal < 300 μg/g; or, for patients with initial Fcal < 300 μg/g, at least 50% decrease of Fcal or normalization of Fcal(< 100 μg/g)(P = 0.001) were predictive of CFREM at W52. Combined endpoint(CDAI < 150 and CRP ≤ 2.9 mg/L and FCal improvement) at W12 was the best predictor of CFREM at W52 with positive predictive value = 100.0%(100.0-100.0)and negative predictive value = 87.1%(75.3-98.9). In multivariable analysis, Fcal improvement at W12 [odd ratio(OR) = 45.1(2.96-687.9); P = 0.03] was a better predictor of CFREM at W52 than CDAI < 150 [OR = 9.3(0.36-237.1); P = 0.145]and CRP < 2.9 mg/L(0.77-278.0; P = 0.073).CONCLUSION The combined monitoring of CDAI, CRP and Fcal after anti-TNF induction therapy is able to predict favorable outcome within one year in patients with CD.

关键词： Biomarkers Crohn's disease Faecal calprotectin Crohn's disease activity index C-reactive protein Tight control Anti-tumor necrosis factor

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Faecal incontinence： Current knowledges and perspectives

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World Journal of Gastrointestinal Pathophysiology 2016年第1期7卷 59-71页

作者： Alban Benezech Michel bouvier Véronique Vitton Service de Gastroentérologie Hôpital NordAssistance Publique-Hôpitaux de Marseille13915 MarseilleFrance Plateforme d’interface clinique CRN2M CNRS UMR 7286Aix-Marseille Université13915 MarseilleFrance

Faecal incontinence(FI) is a disabling and frequent symptom since its prevalence can vary between 5% and 15% of the general population. It has a particular negative impact on quality of life. Many tools are currently available for the treatment of FI, from conservative measures to invasive surgical treatments. The conservative treatment may be dietetic measures, various pharmacological agents, anorectal rehabilitation, posterior tibial nerve stimulation, and transanal irrigation. If needed, patients may have miniinvasive approaches such as sacral nerve modulation or antegrade irrigation. In some cases, a surgical treatment is proposed, mainly external anal sphincter repair. Although these different therapeutic options are available, new techniques are arriving allowing new hopes for the patients. Moreover, most of them are non-invasive such as local application of an α1-adrenoceptor agonist, stem cell injections, rectal injection of botulinum toxin, acupuncture. New more invasive techniques with promising results are also coming such as anal magnetic sphincter and antropylorus transposition. This review reports the main current available treatments of FI and the developing therapeutics tools.

关键词： Faecal incontinence Treatment

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Operational Protocol for Detection of Contamination by Actinides U,Pu and Am in Urine Using Calixarene Columns:From Mineralization to ICP-MS Measurement

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American Journal of Analytical Chemistry 2017年第5期8卷 317-333页

作者： Celine bouvier-Capely Alexandre Legrand Aurelie Sylvain Annabelle Manoury Francois Rebiere Laboratoire de Radiochimie Service de Dosimetrie InternePRP-HOMInstitut de Radioprotection et Surete Nucleaire(IRSN)Fontenay-aux-RosesFrance

Individual monitoring of workers exposed to the risk of intake of actinides requires suitable methods for measuring low level of excreted activity. The current protocols used for actinides analysis in bioassay are usually complicated and highly time consuming. In this work, a protocol based on the microwave digestion of urines followed by the separation of actinides using calix[6]arene-based chromatography columns and their measurement by a quadrupole ICP-MS is developed and validated, for the first time, on urine samples containing the three actinides, U, Pu and Am. With this protocol, the total analysis time is about 2 days, including the mineralization of urine and the chromatographic separation of actinides. Detection limits of actinides in urine are determined and compared to those obtained after “dilute and shoot” ICP-MS analysis or after alpha spectrometry measurement.

关键词： Actinides Urine CalixArene Analysis ICP-MS

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聚合物老化的介电性质

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老化通讯 1973年第2期 52-54页

作者： B.bouvier

导言老化可以改变聚合物的介电吸收,特别是如果偶极的产生是在非极性聚合物的初期的话。本工作的目的是要证实诱导吸收谱带的特性与在一老化聚合物中由于老化过程而断链或交联而引起结构的改变之间的关系。

关键词：聚合物大分子化合物吸收谱带介电性质电性介电吸收

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Validation and Comparison of Two Calibration Methods for the Measurement of Stable Iodine in the Urinary Matrix by ICP-MS:Standard Addition *** Calibration

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American Journal of Analytical Chemistry 2017年第4期8卷 245-263页

作者： Geraldine Landon Celine bouvier-Capely Alexandre Legrand Thibaud Sontag Gregory Finance Mailie Saint-Hilaire Francois Rebiere Xavier Millot Valerie Renaud-Salis Michelle Agarande Institute for Radiological Protection and Nuclear Safety(IRSN) Fontenay-aux-RosesFrance The French Alternative Energies and Atomic Energy Commission(CEA) Gif-sur-YvetteFrance

Background: In the context of a nuclear reactor accident, thyroid is the main target organ of radioactive iodines. To avoid as much as possible thyroid disorders or even cancer development, it is recommended to administer a single dose of potassium iodide to people at risk of exposure. Nevertheless, the Fukushima Dai-ichi disaster has pointed out many questions about the conditions of stable iodine prophylaxis implementation highlighting the need for reflection further revision of the actual “iodine doctrine”. Therefore, providing useful data is required notably through the implementation of animal experiments to strengthen current knowledge and to edit new recommendations. Methods: Urinary iodine constitutes a very good indicator to investigate the function of thyroid, its interpretation demands reliable analyses. Prior to perform animal experiments, two calibration methods were designed by our lab and compared together (standard addition and external calibration) to assess the urinary concentration of stable iodine in urine by ICP-MS. They were validated based on several key parameters especially linearity, accuracy and limits of detection (LOD) and quantification (LOQ). Results: The results were nicely satisfying. Indeed, both calibration methods have indicated very good coefficients of correlations, accuracies with low expanded relative uncertainties were obtained. The estimated LOD in the sample for standard addition method and external calibration were fully acceptable, 0.39 μg·L-1 and 0.35 μg·L-1, respectively. All performance criteria have been thus fulfilled successfully. The established methods were proven to be accurate, robust and sensitive. Once validated, both calibration methods were applied to rat urine samples and the results of z-score and Wilcoxon W test concluded that there were no statistically significant differences between both methods.

关键词： Stable Iodine Urine Standard Addition External Calibration Validation

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多层螺旋CT心脏成像诊断主动脉瓣狭窄

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世界核心医学期刊文摘(心脏病学分册) 2007年第6期 41-42页

作者： bouvier E Logeart D Sablayrolles J.-L 马超 Service de Radiologie et de Cardiologie Centre Cardiologique du NordSaint DenisFrance

目的:当前,多层螺旋CT在空间、时间和对比度分辨率方面均有提高,使得CT检查可在瓣膜疾病评估中发挥效用。本研究旨在评估多层CT在识别和量化主动

关键词：主动脉瓣狭窄螺旋 CT

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Obscure bleeding colonic duplication responds to proton pump inhibitor therapy

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World Journal of Gastroenterology 2013年第35期19卷 5940-5942页

作者： Jérémie Jacques Fabrice Projetti Romain Legros Virginie Valgueblasse Matthieu Sarabi Paul Carrier Fabien Fredon Stéphane bouvier Véronique Loustaud-Ratti Denis Sautereau Service d’Hépato-gastro-entérologie CHU Dupuytren

We report the case of a 17-year-old male admitted to our academic hospital with massive rectal *** childhood he had reported recurrent gastrointestinal bleeding and had two exploratory laparotomies 5and 2 years *** emergency abdominal computed tomography scan,gastroscopy and colonoscopy,performed after hemodynamic stabilization,were considered ***-dose intravenous proton pump inhibitor(PPI)therapy was initiated and bleeding stopped *** other massive rectal bleeds occurred 8 h after each cessation of PPI which led to a hemostatic laparotomy after negative gastroscopy and small bowel capsule *** showed long tubular duplication of the right colon,with fresh blood in the duplicated *** lower gastrointestinal bleeding is a difficult medical situation and potentially *** presence of ulcerated ectopic gastric mucosa in the colonic duplication explains the partial efficacy of PPI *** gastrointestinalbleeding responding to empiric anti-acid therapy should probably evoke the diagnosis of bleeding ectopic gastric mucosa such as Meckel’s diverticulum or gastrointestinal duplication,and gastroenterologists should be aware of this potential medical situation.

关键词： Colonic duplication Gastro-intestinal duplication Gastrointestinal bleeding Hemostatic colorectal surgery Proton pump inhibitor therapy

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应用微波辐射溶解地质物质的初步研究

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世界核地质科学 1989年第2期18卷 81-84页

作者： J.L.bouvier G.E.M.Hall 李珍媛

微波辐射能提供一种溶解地质物质的高效率新方法。该法的优点在于时间短、所需试剂量少,相互污染可控制在最小限度内,而且挥发损耗低。最新购置的一种具有排酸雾专门设计的微波炉已用来利用王水-HF浸蚀法来分解一组27个Cu/Ni富硫化物样... 详细信息

微波辐射能提供一种溶解地质物质的高效率新方法。该法的优点在于时间短、所需试剂量少,相互污染可控制在最小限度内,而且挥发损耗低。最新购置的一种具有排酸雾专门设计的微波炉已用来利用王水-HF浸蚀法来分解一组27个Cu/Ni富硫化物样品。将此项初步研究结果与现在使用的测定主要元素、次要元素和微量元素的两种冗长方法进行了比较,所涉及的元素有16种。只有Ni和Si值显示出偏低10％左右,而改进该法步骤会消除这一问题。本项初步研究是最有希望的,计划对其它类型的基质进行验证。

关键词：微波辐射浸蚀法试剂量最小限度本项副样酸雾原子吸收光谱元素分析稀释系数

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