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Recent trends in metal ion based hydrogel biomaterials for tissue engineering and other biomedical applications

Journal of Materials Science & Technology 2021年第4期63卷 35-53页

作者： Gopinathan Janarthanan insup noh Department of Chemical and Biomolecular Engineering Seoul National University of Science and TechnologySeoul01811Republic of Korea Convergence Institute of Biomedical Engineering and Biomaterials Seoul National University of Science and TechnologySeoul01811Republic of Korea

Recently,the metal ion cross-linked hydrogels have gained enormous interest because of its excellent properties like self-healing,fast recovery,biocompatibility and high mechanical properties combined with multi-stimuli *** this review article,we have summarized the recent trends in the development of metal ion cross-linked hydrogels for tissue engineering and biomedical applications.A number of metal ions and their contribution in the synthesis of various cross-linked hydrogels are discussed with respect to their crosslinking mechanisms,compositions,physio-chemical and biological properties.A special emphasis has been given to ferric(Fe^(3+))ion cross-linked hydrogels and their different combinations owing to their numerous researches reported in the recent past with exceptional *** application of these metal ion based hydrogels in biomedical applications including tissue engineering,sensing,wound healing,drug delivery and as tissue adhesive and tissue sealants are reviewed with specific ***,the application of these metal ion cross-linked hydrogels as inks in 3 D printing is explained in a separate ***,the possible toxic effects of the different metal ions and their effects have been *** directions and comprehensive applications of the hydrogels are highlighted.

关键词： properties. biomaterials exceptional

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Frontiers in regenerative medical materials

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Regenerative Biomaterials 2015年第1期2卷 71-76页

作者： Jun Ma insup noh In-Seop Lee Shengmin Zhang Advanced Biomaterials and Tissue Engineering Center Huazhong University of Science and TechnologyWuhan 430074China Department of Chemical and Biomolecular Engineering Seoul National University of Science and TechnologySeoul 139-743 Korea Convergence Institute of Biomedical Engineering and Biomaterials Seoul National University of Science and TechnologySeoul 139-743 Korea Institute of Natural Sciences Yonsei UniversitySeoul 120-749Korea

Based on the last 10 successful series of the China–Korea Symposium on Biomaterials and Nano-biotechnology,we initiated a new invitation-based bilateral forum for established leaders and emerging young scientists in the field,the 2014 China–Korea symposium on biomimetic and regenerative medical materials,which was held from November 26 to 28 in Wuhan,*** the past decade,a lot of breakthrough achievements in biomedical materials and regenerative medicine have been made in our two ***,biomaterials science and engineering has been evolved into a critical stage of bioactive integration and tissue regeneration from a simple functional replacement and *** and regenerative medical materials will become main topics in the field.

关键词： breakthrough initiated regenerative

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