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Narcea—an unknown,ancient cultivated rose variety from northern Spain

Horticulture Research 2020年第1期7卷 2217-2228页

作者： María-Carmen Martínez José-Luis Santiago Susana Boso Pilar Gago inmaculadaálvarez-acero María-Estela De Vega Miguel Martínez-Bartolomé RafaelÁlvarez-Nogal Pilar Molíst Matteo Caser Valentina Scariot Daniel Gómez-García Misión Biológica de Galicia(CSIC) Carballeira 8Salcedo 36143 PontevedraSpain Instituto de Ciencia y Tecnología de Alimentos y Nutrición(CSIC)(Spain) C/JoséAntonio Novais 1028040 MadridSpain Departamento de Biología Molecular-Área de Biología Celular Universidad de LeónCampus de Vegazana s/n24071 LeónSpain Grupo Neurolamb Biología funcional y Ciencias de la SaludUniversidad de Vigo(Spain)36310 As Lagoas-MarcosendeSpain Department of Agricultural Forest and Food SciencesUniversity of TorinoLargo Paolo Braccini 210095 GrugliascoTurinItaly Instituto Pirenaico de Ecología(CSIC) Dpto.Conservación de Ecosistemas NaturalesAvda.Montaña S/NZaragoza50016 ZaragozaSpain

The present work reports the discovery and the complete characterisation of an ancient cultivated rose variety found growing in a private garden in the southwest of the Principality of Asturias(northern Spain).The variety is here given the name *** majority of roses currently cultivated belong to the so-called group of‘Modern Roses’,all of which were obtained after 1867 via artificial crosses and improvement *** are destined for ornamental *** the 19th century,the great majority of the many ancient cultivated roses in Europe were used in perfumery and cosmetics,or had medicinal *** damascena and Rosa centifollia are still grown and used by the French and Bulgarian perfume *** Asturian Massif of the Cantabrian Mountain Range provides a natural habitat for some 75%of the wild members of the genus Rosa,but until now there was no evidence that this area was home to ancient cultivated roses.A complete botanical description is here provided for a discovered ancient *** is also characterised according to a series of sequence tagged microsatellite sites,and its agronomic features are *** addition,a histological description(optical and scanning electronic microscope studies)of the petals is offered,along with an analysis of the volatile compounds present in these organs as determined by solid phase microextraction and gas chromatography-mass *** results reveal the uniqueness of this ancient type of rose and suggest it may be of interest to the perfume industry.

关键词： ancient southwest majority

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Targeting harmful effects of non-excitatory amino acids as an alternative therapeutic strategy to reduce ischemic damage

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Neural Regeneration Research 2025年第9期20卷 2454-2463页

作者： Victoria Jiménez Carretero IrisÁlvarez-Merz Jorge Hernández-Campano Sergei A.Kirov Jesús M.Hernández-Guijo Department of Pharmacology and Therapeutic School of MedicineUniv.Autónoma de MadridMadridSpain Ramón y Cajal Institute for Health Research(IRYCIS) Neurobiology-Research ServiceHospital Ramón y CajalMadridSpain Institute of Neurobiology Faculty of Mathematics and Natural SciencesHeinrich Heine University DüsseldorfDüsseldorfGermany Department of Neuroscience and Regenerative Medicine&Department of Neurosurgery Medical College of Georgia at Augusta UniversityAugustaGAUSA

The involvement of the excitatory amino acids glutamate and aspartate in ce rebral ischemia and excitotoxicity is ***,the role of non-excitatory amino acids in brain damage following a stroke or brain trauma remains largely *** release of amino acids by necrotic cells in the ischemic core may contribute to the expansion of the *** findings indicated that the reversible loss of field excitato ry postsynaptic potentials caused by transient hypoxia became irreversible when exposed to a mixture of just four non-excitatory amino acids(L-alanine,glycine,L-glutamine,and L-serine)at their plasma *** amino acids induce swelling in the somas of neurons and astrocytes during hypoxia,along with permanent dendritic damage mediated by N-methyl-D-aspartate *** N-methyl-D-aspartate receptors prevented neuronal damage in the presence of these amino acids during *** is likely that astroglial swelling caused by the accumulation of these amino acids via the alanine-serine-cysteine transporter 2 exchanger and system N transporters activates volume-regulated anion channels,leading to the release of excitotoxins and subsequent neuronal damage through N-methyl-D-aspartate receptor ***,previously unrecognized mechanisms involving non-excitatory amino acids may contribute to the progression and expansion of brain injury in neurological emergencies such as stroke and traumatic brain *** these pathways co uld highlight new therapeutic targets to mitigate brain injury.

关键词： cell swelling N-methyl-D-aspartate receptor non-excitatory amino acids stroke synaptic transmission

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On the Perturbation of Semi-Fredholm Relations with Complemented Ranges and Null Spaces

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Acta Mathematica Sinica,English Series 2010年第8期26卷 1545-1554页

作者： Teresa lvarez Department of Mathematics University of Oviedo

Multivalued semi-Fredholm type linear operators with complemented ranges and null spaces are introduced. Conditions are obtained under which the classes given are stable under compact, strictly singular and strictly c... 详细信息

关键词： Left-Atkinson relation right-Atkinson relation strictly singular strictly cosingular perturbation

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Shop&Go:TSP heuristics for an optimal shopping with smartphones

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Science China(Information Sciences) 2013年第11期56卷 45-56页

作者： inmaculada PARDINES Victoria LOPEZ Department of Computer Architecture Faculty of Computer Science Universidad ComplutenseMadrid 28040 Spain

Mobile technology has been under constant growth in last *** emergence of smartphones has encouraged the development of a wide variety of mobile *** of them are related to daily *** this regard,we propose the Shop&Go mobile application which allows a supermarket customer to do the shopping covering the shortest distance1).An analysis of the routing problem applied to an efcient way of doing the shopping is made.A map with items distribution and distances between products is provided by the *** on these information two heuristics have been proposed to do the shopping following the optimum *** heuristics have been compared,proving that neither of them can be defned as the best one in all *** products in the shopping list determine which is the best solution for each ***,both algorithms have been included in our application,letting the user decide which route he/she wants to ***&Go has also other functionalities which are extensively described in the *** over an HTC Desire mobile are shown to demonstrate the proper tool ***,a study of consumer acceptance has been made to know its possibilities of success in the mobile technology market.

关键词： mobile applications routing problems Android operating system shopping list optimum path

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The effect of ethanol fuel dilution on oil performance and MoDTC tribofilms formation and composition

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Friction 2024年第9期12卷 2108-2125页

作者： Juan RUIZ-acero Felipe KESSLER Henara COSTA Tiago COUSSEAU Polytechnic School Universidade de São PauloSão Paulo 05508-030Brazil School of Food and Chemistry Universidade Federal do Rio GrandeRio Grande 96203-000Brazil School of Engineering Universidade Federal do Rio GrandeRio Grande 96203-900Brazil Mechanical Engineering Department Univ.Tecnológica Federal do ParanáCuritiba 81280-340Brazil University of Newcastle CallaghanSW 2308Australia

Ethanol has emerged as a promising alternative to fossil fuels,but its use can lead to significant dilution in lubricants,particularly during cold start or heavy *** dilution can affect the performance of additives,including friction modifiers like molybdenum dithiocarbamate(MoDTC),which are designed to reduce friction under extreme contact *** research suggests that ethanol may impact the performance of MoDTC,prompting this study’s goal to investigate the effects of ethanol on MoDTC tribofilms and their friction response under boundary lubrication ***,reciprocating tribological tests were performed with fully formulated lubricants containing MoDTC with varying ethanol *** results indicate that a critical ethanol dilution level inhibits friction reduction by MoDTC activation,resulting in friction coefficients(COFs)similar to the base *** tested with simple mixtures of polyalphaolefin(PAO)+MoDTC showed increased COFs with added *** of tested surfaces using Raman spectroscopy,X-ray photoelectron spectroscopy(XPS),and X-ray absorption spectroscopy near the edge structure(XANES)revealed the presence of sulfates,MoO_(3),MoS_(2),and MoS_(x)O_(y)compounds in the tribofilms formed on the surfaces,with and without ethanol diluted in the ***,the addition of ethanol increased the sulfates and MoO_(3)content of the tribofilms at the expense of friction-reducing compounds such as MoS_(2)and MoS_(x)O_(y).These findings suggest that ethanol dilution in lubricants containing MoDTC creates an oxygen-rich interfacial medium that favors the formation of compounds with insufficient friction-reducing capabilities.

关键词： molybdenum dithiocarbamate(MoDTC) ethanol tribofilm friction modifier additive lubricant

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On Regular Linear Relations

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Acta Mathematica Sinica,English Series 2012年第1期28卷 183-194页

作者： T.lvarez Department of Mathematics University of Oviedo33007OviedoAsturiasSpain

For a closed linear relation in a Banach space the concept of regularity is introduced and studied. It is shown that many of the results of Mbekhta and other authors for operators remain valid in the context of multivalued linear operators. We also extend the punctured neighbourhood theorem for operators to linear relations and as an application we obtain a characterization of semiFredholm linear relations which are regular.

关键词： Regular linear relation polynomial in a linear relation semiFredholm linear relation

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Recovery of carbon monoxide from flue gases by reactive absorption in ionic liquid imidazolium chlorocuprate(I): Mass transfer coefficients

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Chinese Journal of Chemical Engineering 2015年第5期23卷 769-774页

作者： Gabriel Zarca inmaculada Ortiz Ane Urtiaga Department of Chemical and Biomolecular Engineering Universidad de Cantabria Av. Los Castros s/n.

Recovery of carbon monoxide from flue gases by selective absorption of carbon monoxide in an imidazolium chlorocuprate（l） ionic liquid is considered in this work as an alternative to the use of molecular volatile solvents such as aromatic hydrocarbons. The present work evaluates the CO mass transfer rates from the gas phase to the ionic liquid solutions in the absence of chemical reaction. To that end, carbon dioxide was employed as an inert model gas and absorption experiments were performed to assess the influence of different process variables in a batch reactor with fiat gas-liquid interface. The experimental mass transfer coefficients showed significant var- iation with temperature, （3.4-10.9） × 10^-7 m·s^-1 between 293 and 313 K; stirring speed, （10.2- 33.1）× 10^-7 m.s 1 between 100 and 300 r·min^-1; and concentration of copper（1）, （6.6-10.2） × 10^-7 m·s^-1 between 0.25 and 2 mol· L^- 1. In addition, the mass transfer coefficients were eventually found to follow a poten- tial proportionality of the type kL ∝μ^-0.5 and the dimensionless correlation that makes the estimation of the mass transfer coefficients possible in the studied range of process variables was obtained： Sh=10^-2.64 Re^1.07 , Sc^0.75,These results constitute the first step in the kinetic analysis of the reaction between CO and imidazolium chlorocuprate（I） ionic liquid that determines the design of the separation units.

关键词： Carbon monoxide Ionic liquid Copper(I)Reactive absorption Mass transfer kinetics Mass transfer coefficient Carbon dioxide

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Mesenchymal stem cells from different sources and their derived exosomes: A pre-clinical perspective

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World Journal of Stem Cells 2020年第2期12卷 100-109页

作者： María álvarez-Viejo Unidad de Terapia Celulary Medicina Regenerativa Servicio de Hematologíay Hemoterapia Hospital Universitario Central de Asturias Plataforma de Terapias Avanzadas Instituto de Investigación Sanitaria del Principado de Asturias

Since the introduction of cell therapy as a strategy for the treatment of many diseases,mesenchymal stem cells have emerged as ideal candidates,yet the underlying mechanisms of their beneficial effects are only partially *** the start of the 21st century,a paracrine effect was proposed as a mechanism of tissue repair by these *** addition,a role was suggested for a heterogeneous population of extracellular vesicles in cell-to-cell *** of these vesicles including exosomes have been isolated from most fluids and cells,as well as from supernatants of in vitro cell *** research in the field of regenerative medicine suggests that exosomes derived from mesenchymal stem cells could be a powerful new therapeutic *** review examines the therapeutic potential of these exosomes obtained from the sources most used in cell therapy:bone marrow,adipose tissue,and umbilical cord.

关键词： Mesenchymal stem cells Exosomes Cellular therapy

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Climate-driven variations in productivity reveal adaptive strategies in Iberian cork oak agroforestry systems

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Forest Ecosystems 2022年第1期9卷 83-93页

作者： José Carlos Pérez-Girón Emilio Rafael Díaz-Varela Pedro Álvarez-Álvarez Department of Organisms and Systems Biology Polytechnic School of MieresUniversity of OviedoE-33600MieresAsturiasSpain Research Group on Planning and Management in Complex Adaptive Socio-Ecological Systems(COMPASSES).School of Engineering University of Santiago de CompostelaE-27002LugoSpain

Background:Cork oak agroforestry systems(AFS)have been managed for centuries by humans to produce cork and other goods and services and have recently been recognised as an important reservoir for biodiversity improvement and ***,despite having recently been included as a natural habitat of community-wide interest within the EU Habitats Directive,these systems are in a critical situation of *** other factors,they are strongly threatened by climate change,the effects of which are also expected to be particularly severe in the Mediterranean *** this study,we aimed to evaluate the influence of climate variability by examining primary production indicators and also to analyse whether the geographical location may have a role in the incidence of the adverse effects of ***:Cork oak AFS were identified in the Forest Map of Spain and the Land use map of Portugal and categorized on the basis of canopy *** climate data from 2001 to 2020 were used to model relationships with climate predictors and proximity to the *** analysis was conducted to identify significant spatial clusters of high-and low-efficiency ***:The responses to the influence of climatic conditions differed among the various cork oak AFS categories,particularly in the forest category,which was less dependent on climate *** humidity and water availability were the main drivers of net primary production(NPP).Carbon use efficiency(CUE)was limited by relative humidity and spring temperature in open *** to the coast proved beneficial,especially in years with adverse weather conditions,but was not a limiting factor for survival of the ***,the results of the hotspot analysis supported the other findings,highlighting high-efficiency areas close to the coast and cold spots grouped in specific areas or dispersed ***:Canopy plays a key role in the influence of climatic conditions,particu

关键词： Net primary production Carbon use efficiency Climate Quercus suber Agroforestry system

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Three-dimensional trees for virtual globes

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International Journal of Digital Earth 2014年第10期7卷 789-810页

作者： Cristina Rebollo inmaculada Remolar Jesus Gumbau Miguel Chover Institute of New Imaging Technologies Universitat Jaume ICastellonSpain

One of the problems in virtual globes technologies is the real-time representation of vegetal *** forest or garden representations,the low detailed plants produce a lack of *** techniques are required to achieve accurate interactive visualisation due to the great number of polygons the vegetal species *** article presents a multi-resolution model based on a geometric representation of vegetal species that allows the application to perform the progressive transmission of the model,that is,the transmission of a simple representation followed by successive refinements of *** has a hardware-oriented design in order to obtain interactive frame *** geometric data of the objects are stored in the graphics processing unit and,moreover,the change from one approximation to another is obtained by performing mathematical calcula-tions in this graphics *** multi-resolution model presented here enables instancing:as many vegetal species as desired can be rendered with different levels of detail,while all of them are accessing the same geometric *** model has been used to build a real-time representation of a not imaginary scenario.

关键词： virtual globes real-time rendering vegetal species level of detail graphics hardware progressive transmission

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