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An intrinsically stretchable multi-biochemical sensor for sweat analysis using photo-patternable ecoflex

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npj Flexible Electronics 2023年第1期7卷 220-228页

作者： Seungwan Kim Joohyuk Kang injun Lee Jinhyeong Jang Chan Beum Park Wonryung Lee Byeong-Soo Bae Wearable Platform Materials Technology Center(WMC) 291 Daehak-roYuseong-guDaejeon 34141Republic of Korea Department of Materials Science and Engineering Korea Advanced Institute of Science and Technology(KAIST)291 Daehak-roYuseong-guDaejeon 34141Republic of Korea Center for Theragnosis Biomedical Research InstituteKISTSeoul 02792Republic of Korea

Ecoflex is widely used in bioelectronics due to its outstanding properties of low modulus and large *** its use as an encapsulation layer in multi-channel wearable devices,a patterning procedure is ***,conventional patterning strategies for Ecoflex,such as soft lithography,punching,and laser ablation,lack sufficient quality and process *** address this,we propose a process-compatible method of patterning Ecoflex by developing Photo-patternable Ecoflex(PPE).The PPE layer,used as an encapsulation layer,effectively dissipates strain energy at homogeneous interfaces,resulting in a 50%increase in electrical conductance under 250%*** PPE,we fabricated intrinsically stretchable multi-sensors that monitor bio-signals like glucose,lactate,pH,and humidity in *** sensors maintain durable sensitivity under strain up to 50%and for 1000 cycles at 20%***,we mounted these stretchable multi-chemical sensors on an arm to monitor glucose and lactate levels in sweat.

关键词： lithography pattern intrinsic

Covalent organic framework nanomedicines:Biocompatibility for advanced nanocarriers and cancer theranostics applications

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Bioactive Materials 2023年第3期21卷 358-380页

作者： Nem Singh Jungryun Kim Jaewon Kim Kyungwoo Lee Zehra Zunbul injun Lee Eunji Kim Sung-Gil Chi Jong Seung Kim Department of Chemistry Korea UniversitySeoul02841South Korea Department of Life Science Korea UniversitySeoul02841South Korea

Nanomedicines for drug delivery and imaging-guided cancer therapy is a rapidly growing research *** unique properties of nanomedicines have a massive potential in solving longstanding challenges of existing cancer drugs,such as poor localization at the tumor site,high drug doses and toxicity,recurrence,and poor immune ***,inadequate biocompatibility restricts their potential in clinical ***,advanced nanomaterials with high biocompat-ibility and enhanced therapeutic efficiency are highly desired to fast-track the clinical translation of *** properties of nanoscale covalent organic frameworks(nCOFs),such as suitable size,modular pore geometry and porosity,and straightforward post-synthetic modification via simple organic transformations,make them incredibly attractive for future *** ability of COFs to disintegrate in a slightly acidic tumor microenvironment also gives them a competitive advantage in targeted *** review summarizes recently published applications of COFs in drug delivery,photo-immuno therapy,sonodynamic therapy,photothermal therapy,chemotherapy,pyroptosis,and combination *** we mainly focused on modifications of COFs to enhance their biocompatibility,efficacy and potential clinical *** review will provide the fundamental knowledge in designing biocompatible nCOFs-based nano-medicines and will help in the rapid development of cancer drug carriers and theranostics.

关键词： doses medicines compatibility

非骨水泥型全髋置换术中股骨假体前倾角的医生估测值与CT测量值的比较

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中华骨科杂志 2010年第3期30卷 I0001-I0006页

作者： Lawrence D. Dorr, MD ZhinianWan, MD AamerMalik, MD injun Zhu, MD Manish Dastane, MD Prashant Deshmane, MD 彭吴(译) Investigation performed at The A rthritis Institute at Good Samaritan Hospital Los A ngeles California 武汉大学人民医院骨科 430060

背景：全髋关节置换股骨假体前倾角的术中估测，通常由手术医生通过假体柄和股骨髁平面的相对关系进行肉眼观察。目前，普遍认为前倾角范围应在10°-20°，但是我们怀疑在非骨水泥型股骨假体植入过程中始终保持前倾角在该范围内比想像... 详细信息

背景：全髋关节置换股骨假体前倾角的术中估测，通常由手术医生通过假体柄和股骨髁平面的相对关系进行肉眼观察。目前，普遍认为前倾角范围应在10°-20°，但是我们怀疑在非骨水泥型股骨假体植入过程中始终保持前倾角在该范围内比想像的更困难。方法：我们前瞻性评估了109髋（99例患者）全髋置换手术股骨假体前倾角的准确度，这些病例中股骨假体植入没有应用骨水泥。术后我们通过股骨远端髁上和后髁确定股骨干平面，使用股骨CT三维重建测量股骨柄前倾角。然后计算偏倚和测量精度。结果：手术医生对股骨假体柄前倾角估测的平均值（和标准差）为9．6°±7．2°（范围，-8°-28°），CT测量的股骨柄前倾角的平均值为10．2°±7．5°（范围，-8．6°～27．1°）（p=0．324）。手术医生估测值与CT测量值之间的相关系数是0．688，组内相关系数为0．801。通过CT测量的前倾角中，49例（45％）前倾角在10°～20°，43例（39％）前倾角在0°～9°，8例（7％）前倾角〉20°，9例（8％）出现后倾。结论：手术医生对非骨水泥型股骨柄前倾角估测的精确度较差，常没有在预定的10°～20°。该发现更加证实通过评估股骨柄和臼杯的联合前倾角以获得安全活动范围的重要性。

关键词： CT测量值非骨水泥型股骨假体手术医生前倾角全髋置换术测值组内相关系数

HEAD-NECK DISCONNECT Fixing Poor Posture

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城市漫步（GBA版） 2017年第1期 45-45页

作者： injun Kim 不详

Forward head postlire is a correctible condition that can be the result of trau-ma(intense and fast stress on the neck)or longterm cumulative stress such as poor *** x-rays shown here are examples of before and after ... 详细信息

关键词： such head correct

THE BASICS OF BACK PAIN How Proper Chiropractic Care Can Improve Quality of Life

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城市漫步（GBA版） 2016年第12期 51-51页

作者： injun Kim 不详

Many patients seek chiropractic care to alleviate pain and other health-related *** is the only profession that is dedicated to finding and cor-recting vertebral subluxations(also known as spinal misalignments).

关键词： Chiropractic vertebral Care