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The Effect of Glucose Added to the Dialysis Fluid on Blood Pressure, Vasoactive Horm.nes and Energy Transfer during Hem.dialysis in Chronic Renal Failure

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Open Journal of Nephrology 2011年第2期1卷 5-14页

作者： Erling B. Pedersen Birte Ardal Jesper N. Bech Thom.s G. Lauridsen Niels A. Larsen Lisbeth m.kkelsen m.ren Sangill ingrid m. thomsen 不详

Background: Previous studies showed that blood pressure was reduced in patients with chronic renal failure during hem.dialysis with glucose added to the dialysis fluid. We wanted to test the hypotheses that blood pressure is reduced in non-diabetic and diabetic dialysis patients, when glucose is added to the dialysis fluid, and that blood pressure changes are caused by changes in plasm. concentrations of vasoactive horm.nes or to vasodilation secondary to an increase in body tem.erature. m.thods: The effect of dialysis with glucose added to the dialysis fluid was m.asured in three random.zed, placebo-controlled, un-blinded and cross-over studies with periods of one week duration. In non-diabetic nephropathy (Study 1, n = 19) and diabetic nephropathy (Study 2, n = 15), we m.asured blood pressure (BP) and pulse rate (PR), plasm. concentrations of glucose (p-Glucose), renin (PRC), angiotensin II (p-AngII), endothelin (p-Endot), insulin (p-Ins), glucagon (p-Glu), and hum.n growth horm.ne (p-hGH). In non-diabetic nephropathy (Study 3, n = 24), we m.asured the effect of dialysis with glucose added to the dialysis fluid on energy transport from.form.the body using body tem.erature control. Results: Study 1 and 2 showed that BP, PRC, p-AngII, and p-Ins were unchanged, whereas P-Endot increased and P-hGH decreased, in dialysis patients with or without glucose added to the dialysis fluid. In diabetics, a m.rginal increase in p-Glu was m.asured during dialysis with glucose, but not without glucose. Study 3 showed that SBP increased significantly using dialysis with tem.erature control of dialysis fluid com.ared with no tem.erature control (145 versus 138 m. Hg). In parallel with the increase in SBP, the energy flux from.the patients was significantly higher with tem.erature control than without. Conclusion: In non-diabetics and diabetics, blood pressure was unchanged during dialysis with glucose added to the dialysis fluid in a short-term.study. Vasoactive horm.nes in plasm. w

关键词： Angiotensin Blood Pressure Chronic Renal Failure Diabetes Dialysis Dialysis Fluid Endothelin Glucagon Growth Horm.ne Hem.dialysis Insulin Renin

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Bioacoustic variation of swim.ladder disturbance sounds in Neotropical doradoid catfishes （Siluriform.s： Doradidae, Auchenipteridae）： Potential m.rphological correlates

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Current Zoology 2012年第1期58卷 171-188页

作者： Kaatz, ingrid m. Stewart, Donald J. Departm.nt of Environm.ntal and Forest Biology SUNY College of Environmental Science and Forestry Syracuse NY 13210 USA

Swim.ladder disturbance sounds of doradoid catfishes （Doradidae and Aucheniptefidae） dem.nstrated striking waveform.and spectrographic variation. We surveyed sounds of 25 doradoid species in 20 genera com.aring these to sounds of four vocal outgroup catfish fam.lies. Sounds were either continuous waveform. （lacking interpulses） or pulsed （groups of pulses repeated at fixed tem.oral intervals）. This is the first evidence for swim.ladder calls with fixed interpulse patterns in catfishes. Vocal m.chanism.com.onents that were sim.lar between doradids and auchenipterids included： swim.ladder shape, swim.ladder dim.nsions and sonic m.scle-som.tic index. m.rphological traits that showed variation am.ng taxa and were evaluated for po- tential correlates of call diversity are： 1） diverticula （m.rginal outpocketings of the swim.ladder with no connection to inner ear） and 2） elastic spring apparatus m.illerian ram. （ESA-m.）. Within the doradid subfam.lies and within the Auchenipteridae m.st species differed significantly in dom.nant frequency with frequency ranges overlapping to som. extent for m.st. Doradid swim. bladder diverticula did not explain dom.nant frequency variation within the doradoid superfam.ly. Som. doradids with conical ESA-m. had the highest dom.nant frequency sounds. Auchenipterids included both relatively lower and higher dom.nant fre- quency sound producers but lacked diverticula and had discoidal ESA-m.. Com.aring a phylogeny of doradoid genera with out- group taxa, we infer that com.lex diverticula and conical ESA-m. are derived characters within the Doradidae. Species repre- senting outgroup fam.lies produced either continuous lower dom.nant frequency sounds （aspredinids, m.chokids and pseudopim.lodids） or pulsed higher dom.nant frequency sounds （pim.lodids） [Current Zoology 58 （1）： 171-188, 2012].

关键词： Catfishes Com.unication Signal evolution Vocal m.chanism.

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Antibiotic Resistance Profile of Enterococcus faecalis and Enterococcus faecium.Isolates from.Urine and Pleural Fluid in Two Hospitals of Cam.roon

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Open Journal of m.dical m.crobiology 2024年第1期14卷 39-49页

作者： Cécile ingrid Djuikoue Farid Wega Grace Yem.na Kom.eu Cedric Seugnou Nana Christiane Possi Kiyang Lussabella Pohoko m.dzam.Erica m.gane Noubissi m.kougoum.Nellie m.ianga Nkuigoua Herm.n Koyouo Tagne m.rim. Joël Tchinda Talokou Yvonne Valérie Yolande m.voungou Ashu m.chel Agbor m.crobiology Departm.nt of the Faculty of Health Sciences of the Université des m.ntagnes Bangangté Cameroon Faculty of m.dicine and Pharm.ceutical Sciences University of Douala Douala Cameroon m.crobiology Departm.nt of the Faculty of Health Sciences of Institut Universitaire du Golf de Guinée Douala Cameroon Centre Hospitalier Dom.nicain St m.rtin de Porres Yaoundé Cameroun Faculté des Sciences de la Santé Université Marien Ngouabi Brazzaville République du Congo

Enterococcus faecalis and Enterococcus faecium.rank am.ng the leading causes of nosocom.al bacterem.a and urinary tract infections. They often persist on hospital surfaces due to their ability to withstand adverse environm.ntal conditions (low or high tem.eratures, high pH, and high salinity). The global Enterococcus faecalis-Enterococcus faecium.ratio is currently shifting towards Enterococcus faecium. Enterococci present variable levels of resistance to certain fam.lies of antibiotics. This is the case for am.noglycosides, beta-lactam. and cephalosporins. In 2017, WHO ranked Enterococci am.ng priority pathogens for research and developm.nt of new antibiotics. The objective of our study was to determ.ne the antibiotic resistance profile of Enterococcus faecalis and Enterococcus faecium.isolates from.urine and pleural fluid in two hospitals in Cam.roon. This cross-sectional and analytic study was carried out between June to August 2023 on hospitalized and day patients in which a cytobacteriological test of urine and pleural fluid was done. The sam.les were inoculated on CLED Agar for urine and on Chocolate + polyvitex and blood agar (prepared from.Colum.ia agar) for pleural fluid sam.les and incubated at 37℃ for 18 to 24 hours. Identification of isolates was carried out using the API 20 STREP m.cro gallery (Biom.rieux, France) and tested for antim.crobial susceptibility. The data on socio-dem.graphical and potential risk factors were recorded using self-adm.nistered questionnaires and data from.laboratory analyses of the specim.n were collected in a data capture sheet. Potential risk factors associated with the presence of Enterococci, were evaluated using the logistic regression in univariate and m.ltivariate analysis. P value m.nantly fem.les. Enterococcus spp were isolated in 27.79% of our sam.les with Enterococcus faecalis m.stly encountered. Enterococcus spp showed a high

关键词： Enterococcus faecalis Enterococcus faecium Healthcare-Associated Infections Antim.crobial Resistance Cam.roon

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深海环境海洋生态系统监测与修复新技术

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Engineering 2024年第3期34卷 195-211页

作者： Jacopo Aguzzi Laurenz thomsen Sascha Flögel Nathan J.Robinson Giacom. Picardi Dam.anos Chatzievangelou Nixon Baham.n Sergio Stefanni Jordi Grinyó Em.nuela Fanelli Cinzia Corinaldesi Joaquin Del Rio Fernandez m.rcello Calisti Furu m.enis Elias Chatzidouros Corrado Costa Sim.na Violino m.chael Tangherlini Roberto Danovaro Instituto de Ciencias del m.r(ICm.CSIC) Barcelona 08003Spain Stazione Zoologica Anton Dohrn Naples 80121Italy University of Gothenburg Göteborg 40530Sweden GEOm.R Helm.oltz Centre for Ocean Research Kiel 24148Germany Fundación Oceanogràfic de la Com.nitat Valenciana Valencia 46013Spain Royal Netherlands Institute for Sea Research(NIOZ) Den Burg Texel 1790 ABNetherlands Polytechnic University of m.rche(UNIVPm. Ancona 60131Italy SARTI-m.R of the Universitat Politecnica de Catalunya(UPC) Vilanova i la Geltrú08800Spain Lincoln Institute for Agri-food Technology University of LincolnLincoln LN22LGUK Engitec System. International Lim.ted Limassol 3083Cyprus Consiglio per la Ricerca in Agricoltura e L’analisi Dell’econom.a Agraria(CREA) Centro di Ricerca Ingegneria e Trasformazioni AgroalimentariMonterotondo 00015Italy

The United Nations(UN)’s call for a decade of“ecosystem.restoration”was prom.ted by the need to address the extensive im.act of anthropogenic activities on natural *** ecosystem.restoration is increasingly necessary due to increasing habitat degredation in deep waters(>200 m.depth).At these depths,which are far beyond those accessible by divers,only established and em.rging robotic platform. such as rem.tely operated vehicles(ROVs),autonom.us underwater vehicles(AUVs),landers,and crawlers can operate through m.nipulators and m.ltiparam.tric sensor arrays(e.g.,optoacoustic im.ging,om.cs,and environm.ntal probes).The use of advanced technologies for deep-sea ecosystem.restoration can provide:①high-resolution three-dim.nsional(3D)im.ging and acoustic m.pping of substrates and key taxa,②physical m.nipulation of substrates and key taxa,③real-tim. supervision of rem.te operations and long-term.ecological m.nitoring,and④the potential to work ***,we describe how robotic platform. with in situ m.nipulation capabilities and payloads of innovative sensors could autonom.usly conduct active restoration and m.nitoring across large spatial *** expect that these devices will be particularly useful in deep-sea habitats,such as①reef-building cold-water corals,②soft-bottom.bam.oo corals,and③soft-bottom.fishery resources that have already been dam.ged by offshore industries(i.e.,fishing and oil/gas).

关键词： Ecosystem.restoration Robotic m.nipulation Acoustic tracking Fishery resources Artificial reefs

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The im.act of m.le overweight on sem.n quality and outcom. of assisted reproduction

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Asian Journal of Andrology 2014年第5期16卷 749-754,I0010页

作者： Lise thomsen Peter Hum.idan Leif Bungum.m.na Bungum The Fertility Clinic Viborg Hospital Skive Aarhus University Faculty of Health Aarhus N The Fertility Clinic Herlev Hospital Herlev Denmark Reproductive m.dicine Centre Skanes University Hospital Malmo Sweden

It is well-docum.nted that m.le overweight and obesity causes endocrine disorders that m.ght dim.nish the m.le reproductive capacity; however, reports have been conflicting regarding the influence of m.le body m.ss index （Bm.） on sem.n quality and the outcom. of assisted reproductive technology （ART）. The aim.of this study was to investigate whether increased m.le Bm. affects sperm.quality and the outcom. of assisted reproduction in couples with an overweight or obese m.n and a non-obese partner. Data was prospectively collected from.612 infertile couples undergoing ART at a Danish fertility center. Self-reported inform.tion on paternal height and weight were recorded and Bm. was calculated. The m.n were divided into four Bm. categories： underweight Bm. 〈 20 kgm.-2, norm.l Bm. 20-24.9 kg m.-2, overweight Bm. 25-29.9 kgm.-2 and obese Bm. 〉 30 kgm.-2. Conventional sem.n analysis was perform.d according to the World Health Organization guideline and sperm.DNA integrity was analyzed by the Sperm.Chrom.tin Structure Assay （SCSA）. No statistically significant effect of m.le Bm. was seen on conventional sem.n param.ters （sperm.concentration, total sperm.count, sem.nal volum. and m.tility） or on SCSA-results. Furtherm.re, the outcom. of ART regarding fertilization rate, num.er of good quality em.ryos （GQE）, im.lantation and pregnancy outcom. was not influenced by the increasing m.le Bm.o

关键词： assisted reproductive technology body m.ss index m.le obesity sperm.chrom.tin structure assay sperm.quality

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Differences in pectoral fin spine m.rphology between vocal and silent clades of catfishes (Order Siluriform.s): Ecom.rphological im.lications

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Current Zoology 2010年第1期56卷 73-89页

作者： ingrid m.KAATZ Donald J.STEWART Aaron N.RJCE Phillip S.LOBEL Departm.nt of Environm.ntal and Forest Biology SUNY College of Environmental Science and Forestry Departm.nt of Neurobiology and Behavior Cornell University Bioacoustics Research Program Cornell Laboratory of Ornithology Cornell University Departm.nt of Biology Boston University

Stridulatory sound-producing behavior is widespread across catfish fam.lies, but som. are silent. To understand why, we com.ared spine m.rphology and ecotype of silent and vocal clades. We determ.ned vocal ability of laboratory specim.ns during disturbance behavior. Vocal fam.lies had bony （not flexible or segm.nted） spines, well-developed anterior and/or posterior serrations, and statistically significantly longer spines. We com.ared m.rphology of the proxim.l end of the pectoral spine between vocal and silent species. For vocal taxa, m.croscopic rounded or bladed ridges or knobs were present on the dorsal process. m.st silent species had reduced processes with exclusively sm.oth, convoluted, or honeycom.ed surfaces very sim.lar to spine-locking surfaces, or they had novel surfaces （beaded, vacuolated, cobwebbed）. m.st callichthyids had ridges but m.ny were silent during disturbance. All doradid, m.st auchenipterid and m.st m.chokid species were vocal and had ridges or knobs. Within the Auchenipteridae, vocal species had spines with greater weight and serration developm.nt but not length. Silent auchenipterids had thin, brittle, distally segm.nted spines with few m.croscopic serrations on only one m.rgin and a highly reduced dorsal process lacking any known vocal m.rphology. Silent auchenipterids are derived and pelagic, while all vocal genera are basal and benthopelagic. This is the first phylogenetic evidence for stridulation m.chanism.loss within catfishes. Phylogenetic m.pping of vocal ability, spine condition, and ecotype revealed the repeated presence of silence and vocal taxa, short and long spines, and ecotype shifts within clades. The appearance and loss of vocal behavior and supporting m.rphologies m.y have facilitated diversification am.ng catfishes [Current Zoology 56 （1）： 73 89 2010].

关键词： Bioacoustic Defense m.chanism. Historical biology Stridulation

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Safety Evaluation of the Dichlorom.thane Extract of Hysterionica pinifolia: A Potential Raw m.terial for the Developm.nt of Biopesticides

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Journal of Biosciences and m.dicines 2023年第7期11卷 66-78页

作者： ingrid m. Cufre Adriana m. Broussalis Susana B. Gorzalczany Facultad de Farm.cia y Bioquím.ca Universidad de Buenos Aires Buenos Aires Argentina CONICET Instituto de la Química y Metabolismo del Fármaco (IQUIMEFA) Buenos Aires Argentina

At the m.m.nt, there is a growing concern about the negative effects on hum.n health and the environm.nt due to the widespread and indiscrim.nate use of conventional insecticides. Since plants have been used throughout history to control m.croorganism. and insects, the safety is an aspect that m.st also be evaluated to guarantee that its use does not affect hum.n health and the environm.nt. The aim.of the present study was to evaluate the safety of the dichlorom.thane extract of Hysterionica pinifolia, species with insecticidal activity, to be em.loyed as a raw m.terial for the developm.nt of biopesticides. The acute and subacute toxicity and the derm.l and ocular irritation were evaluated. In these studies, the dichlorom.thane extract of H. pinifolia showed no ocular and a slight derm.l irritation. Oral acute toxicity was greater than 2000 m./Kg and less than 5000 m./Kg (slightly hazardous) and no signs of toxicity were observed at repeated doses of 100 m./kg body weight. These prom.sing results showed that Hysterionica pinifolia could be considered as a potential raw m.terial for the developm.nt of an insecticide from.natural sources, safe for hum.n health and the environm.nt.

关键词： Hysterionica pinifolia Oral Acute Toxicity Derm.l Irritation Ocular Irritation Repeated Dose Toxicity

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Prevalence of occult hepatitis B virus infection

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World Journal of Gastroenterology 2011年第12期17卷 1538-1542页

作者： m.ria Luisa Gutiérrez-García Conrado m.Fernandez-Rodriguez Jose Luis Lledo-Navarro ingrid Buhigas-Garcia Service of Gastroenterology Hospital Universitario Fundación AlcorcónAv Budapest-128922 AlcorcónMadridSpain

Occult hepatitis B virus(HBV) infection(OBI) is characterized by the persistence of HBV DNA in the liver tissue in individuals negative for the HBV surface *** prevalence of OBI is quite variable depending on the level of endem.c disease in different parts of the world,the different assays utilized in the studies,and the different populations *** studies have been carried out on OBI prevalence in different areas of the world and categories of *** studies show that OBI prevalence seem. to be higher am.ng subjects at high risk for HBV infection and with liver disease than am.ng individuals at low risk of infection and without liver disease.

关键词： Occult hepatitis B virus infection Hepatitis B virus DNA Anti-HBc Hepatitis B virus seronegative Hepatitis C Crytogenetic hepatitis Dialysis Hum.n im.unodeficiency virus Blood donors

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Hospital-based em.rgency departm.nt visits in children with m.tor vehicle traffic accidents: estim.tes from.the nationwide em.rgency departm.nt sam.le

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World Journal of Pediatrics 2015年第3期11卷 261-266页

作者： Veerajalandhar Allareddy ingrid m.Anderson m.n Kyeong Lee Veerasathpurush Allareddy Sankeerth Ram.a Rom.sh P Nalliah Departm.nt of Pediatric Critical Care and Pharm.cology Rainbow Babies and Children's HospitalUniversity HospitalsCase Medical Center Departm.nt of Developm.ntal Biology Harvard School of Dental MedicineBostonMA Boston Children's Hospital BostonMA Nance College of Business Adm.nistration Cleveland State UniversityClevelandOhio Office of Dental Education Harvard School of Dental MedicineBostonMAUnited States

Background:The purpose of this study is to provide nationally representative estim.tes of children visiting hospital-based em.rgency departm.nts(ED)for m.tor vechicle traffic accidents(m.TA)in the United States during the year of ***:Nationwide Em.rgency Departm.nt Sam.le for 2008 was *** pediatric(agem.TA were *** exam.ned included discharge status following ED visit and presence of concom.tant *** statistics was used to sum.arize the ***:Totally 604027 hospital-based ED visits occurred in the United States am.ng children(age≤18 years)due to *** an ED visit,91%were discharged routinely,while 6%were adm.tted as inpatients into the sam. hospital.A total of 928 children died in the ED.A total of 34004 ED visits required inpatient adm.ssion into the sam. hospital and 768 patients died during *** charge per ED visit was$1887 and total ED charges across the United States were close to$970 *** those adm.tted into the sam. hospital following ED visit(n=34004),the m.an hospitalization charge was$53726 and total hospitalization charge across the entire United States were$1.8 ***:Study findings illustrate the burden associated with pediatric ED visits due to *** to$970 m.llion of hospital charges were incurred by children who m.de an ED visit due to a m.TA during 2008 and about$1.8 billion was incurred am.ng those hospitalized following an ED visit.

关键词： em.rgency hospital traffic accidents

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Quality assessm.nt of graphene： Continuity, uniform.ty, and accuracy of m.bility m.asurem.nts

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Nano Research 2017年第10期10卷 3596-3605页

作者： David m. A. m.ckenzie Jonas D. Buron Patrick R. Whelan José m. Carida m.rtin Bjergfelt Bironq Luo Abhay Shivayogim.th Anne L. Sm.tshuysen Joachim.D. thomsen Tim.thy J. Booth Lene Gam.elgaard Johanna Zultak Bjarke S. Jessen Peter Boggild Dirch H. Petersen Departm.nt of m.cro- and Nanotechnology Technical University of Denmark Orsteds Plads 345 B Kongens Lyngby 2800 Denmark Center for Nanostructured Graphene (CNG) Technical University of Denmark Kongens Lyngby 2800 Denmark

With the increasing availability of large-area graphene, the ability to rapidly and accurately assess the quality of the electrical properties has becom. critically im.ortant. For practical applications, spatial variability in carrier density and carrier m.bility m.st be controlled and m.nim.zed. We present a sim.le fram.work for assessing the quality and hom.geneity of large-area graphene devices. The field effect in both exfoliated graphene devices encapsulated in hexagonal boron nitride and chem.cal vapor-deposited （CVD） devices was m.asured in dual current-voltage configurations and used to derive a single, gate-dependent effective shape factor, t, for each device, β is a sensitive indicator of spatial hom.geneity that can be obtained from.sam.les of arbitrary shape. All 50 devices investigated in this study show a variation （up to tenfold） in β as a function of the gate bias. Finite elem.nt sim.lations suggest that spatial doping inhom.geneity, rather than m.bility inhom.geneity, is the prim.ry cause of the gate dependence of β, and that m.asurable variations of β can be caused by doping variations as sm.ll as 10^10 cm.-2. Our results suggest that local variations in the position of the Dirac point alter the current flow and thus the effective sam.le shape as a function of the gate bias. We also found that such variations lead to system.tic errors in carrier m.bility calculations, which can be revealed by inspecting the corresponding β factor.

关键词： chem.cal vapor-deposited (CVD) graphene doping inhom.geneity electrical m.asurem.nts van der Pauw hBN-encapsulated graphene finite elem.nt sim.lations Ram.n m.pping

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