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Molecular Plant 2009年第5期2卷 990-999页

作者： Willie Abasolo Michaela Eder Kazuchika Yamauchi Nicolai Obel Antje Reinecke Lutz Neumetzler John W.C. Dunlop Gregory Mouille Markus Pauly Herman Hofte ingo Burgert Max-Planck-lnstitute of Colloids and Interfaces Department of Biomaterials Potsdam Germany College of Forestry and Natural Resources University of the Philippines Los Banos Philippines Department of Socio-Environmental Energy Science Kyoto University Japan Max-Planck-lnstitute for Molecular Plant Physiology Potsdam Germany Laboratoire de Biologie Cellulaire UR501 Institute Jean-Pierre Bourgin INRA Versailles France Michigan State University Plant Research Laboratory East Lansing Michigan USA

Plant cell walls, like a multitude of other biological materials, are natural fiber-reinforced composite materials. Their mechanical properties are highly dependent on the interplay of the stiff fibrous phase and the soft matrix phase and on the matrix deformation itself. Using specific Arabidopsis thaliana mutants, we studied the mechanical role of the matrix assembly in primary cell walls of hypocotyls with altered xyloglucan and pectin composition. Standard microtensile tests and cyclic loading protocols were performed on tour1 hypocotyls with affected RGII borate diester cross-links and a hindered xyloglucan fucosylation as well as qua2 exhibiting 50% less homogalacturonan in comparison to wild-type. As a control, wild-type plants （Col-0） and mur2 exhibiting a specific xyloglucan fucosylation and no differences in the pectin network were utilized. In the standard tensile tests, the ultimate stress levels （-tensile strength） of the hypocotyls of the mutants with pectin alterations （mur1, qua2） were rather unaffected, whereas their tensile stiffness was noticeably reduced in comparison to Col-0. The cyclic loading tests indicated a stiffening of all hypocotyls after the first cycle and a plastic deformation during the first straining, the degree of which, however, was much higher for tour1 and qua2 hypocotyls. Based on the mechanical data and current cell wall models, it is assumed that folded xyloglucan chains between cellulose fibrils may tend to unfold during straining of the hypocotyls. This response is probably hindered by geometrical constraints due to pectin rigidity.

关键词： Arabidopsis thaliana mutants cellulose xyloglucan pectin cyclic loading tests.

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Chinese Journal of Traumatology 2022年第5期25卷 272-276页

作者： Nils Muhlenfeld Philipp Stormann ingo Marzi Felix Rosenow Adam Strzelczyk Rene D.Verboket Laurent M.Willems Department of Traurma Hand and Reconstructive SurgeryGoethe University FrankfurtFrankfurt Am MainGermany Epilepsy Center Frankfurt Rhine-Main Department of NeurologyGoethe University FrankfurlFrankfurt Am MainGermany LOEWE Center for Personalized Translational Epilepsy Research(CePTER) Goethe-Universitat FrankfurtFrankfurt Am MainGermany Department of Neurology and Epilepsy Center Hessen Philipps-University MarburgMarburg(Lahn)Germany

Purpose: Epileptic seizures frequently result in distinct physical injuries, fractures, traumatic brain injuries and minor trauma. The aim of this study was to retrospectively determine the frequent injury patterns due to seizure episode and to analyze consecutive acute medical care. Methods: This retrospective mono-center study was conducted at Frankfurt University Hospital, Frankfurt am Main, Germany between January 2007 and December 2017. Epilepsy patients with seizure-related fractures admitted to the emergency department were identified via a retrospective systematic query in the hospital information system using the ICD-10 German modification codes G40.0—G40.9. Patients with an unclear diagnosis of epilepsy were excluded. Sociodemographic as well as disease specific aspects were analyzed. Descriptive and Kruskal—Wallis one-way analysis of variance were used for statistical analysis. Results: A total number of 62 epilepsy patients were included. The mean age was 58.1 years. Fractures concerned the upper extremity most frequently (43.5%,n= 20), and 70.0% (14/20) were humerus fractures. Admission to intensive care unit for acute trauma care was necessary in 29.0% patients (n = 18), and surgery in 45.2% patients (n = 28). Twenty-five patients (26.6%) showed clinical or radiological signs of traumatic brain injury. Provoking factors were identified in 20 patients (32.3%), i.e., acute withdrawal or excess of alcohol (n = 15), relevant sleep deprivation (n = 2), and intoxication or withdrawal of other illegal drugs or trivial infect (n = 1 for each) and non-compliance with anti-seizure drugs (n = 1). A decreased T-score (-1.04 ± 1.15) and Z-score (-0.84 ± 0.75) compared to healthy subjects were found. Conclusion: Fractures in upper extremities, trunk and craniocerebral trauma occur frequently as seizure-induced injuries. Alcohol excess and withdrawal are important provoking factors and should be targeted with preventive measurements to avoid seizure related injuries

关键词： Epilepsy Wounds and injuries Falls Quality of life

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校外科学学习环境中的兴趣建模:系统性文献综述

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中国校外教育 2024年第4期 107-128页

作者：西蒙·内尔-阿斯力别克夫英戈·瓦格纳华静(译) 肖乐琪(译) 吴碧宇(译) 陈斌(译) 王璨(译) Institute for School Pedagogy and Didactics Karlsruhe Institute of Technology KarlsruheGermany 华东理工大学外语学院上海外国语大学贤达经济人文学院外语学院金华开放大学上海理工大学外语学院

校外科学学习环境丰富了许多国家的课堂教学。已有大量研究探讨了校外学习环境所带来的影响,尤其是校外学习环境促进兴趣养成的能力。由于这些研究中运用了不同的兴趣理论,迄今为止,还没有关于该研究领域的综述。因此,本文在全面系统回... 详细信息

校外科学学习环境丰富了许多国家的课堂教学。已有大量研究探讨了校外学习环境所带来的影响,尤其是校外学习环境促进兴趣养成的能力。由于这些研究中运用了不同的兴趣理论,迄今为止,还没有关于该研究领域的综述。因此,本文在全面系统回顾国际文献的基础上,详细分析了兴趣理论在校外学习环境研究中的应用。此外,本文还得出了关于在校外科学学习环境中促进情境兴趣和个体兴趣提升的推论,结果清晰表明,情境兴趣通过这类学习环境得以促进提升。结合不同兴趣理论所提出的影响因素,本文构建了校外学习环境中的学生兴趣模型,该模型可用于指导校外学习环境的开发和进一步完善。

关键词：校外实验室兴趣理论拓展项目

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知识网络的空间极化与扩散研究——以我国生物技术为例

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长江流域资源与环境 2011年第7期20卷 796-801页

作者：汪涛 HENNEMANN Stefan LIEFNER ingo 李丹丹南京师范大学地理科学学院江苏南京210046 Institute of Geography Justus-Liebig University

知识网络是由创造、转移、吸收和应用知识的行为主体在知识的传播与交流过程中彼此联结而形成的网络结构。以国际ISI和国内VIP数据库中2000～2009年发表于生物技术领域的合著论文作者信息统计数据为数据源,基于社会网络分析的理论和方法... 详细信息

知识网络是由创造、转移、吸收和应用知识的行为主体在知识的传播与交流过程中彼此联结而形成的网络结构。以国际ISI和国内VIP数据库中2000～2009年发表于生物技术领域的合著论文作者信息统计数据为数据源,基于社会网络分析的理论和方法,从国际和国内省级层面运用UCINET和Pajek软件分析知识网络的空间极化和扩散规律。总体上看网络仍处于量的扩张期,网络的稳健性正在逐步提高,网络结构开始向成熟型转变。国际层面上看,知识网络的空间极化现象明显。国内层面上看,知识网络由等级结构向扁平结构转变,空间上相应地经历了由一极向多核再向多中心发展的过程。依据知识网络空间分布特征,将知识交流区域分为知识集聚区、知识门户区、知识途径区及知识边缘区四大类型,并对我国的技术创新政策提出对策建议。

关键词：知识网络技术创新社会网络分析极化与扩散

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Rationale for Treatment of Common Cold and Flu with Multi-Ingredient Combination Products for Multi-Symptom Relief in Adults

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Open Journal of Respiratory Diseases 2014年第3期4卷 73-82页

作者： Ron Eccles ingo Fietze Uwe-Bernd Rose Common Cold Centre and Healthcare Clinical Trials Cardiff School of BiosciencesCardiff UniversityCardiffUK Campus Charité Mitte—Schlafmedizinisches Zentrum BerlinGermany Burg Apotheke Konigstein/TaunusGermany

This up-to-date overview will look at the rationale for the recommendation of combination products for multi-symptom relief of common cold and flu. Common cold and flu are defined by their multi-symptom nature with data showing a variety of symptoms reported simultaneously each day over the first six days of illness. Multi-ingredient combination products for multi-symptom relief are formulated to safely, simply, and simultaneously treat multiple symptoms when used as directed. The rationale for the formulation combination products for common cold and flu is therefore practical, logical and reasonable. No evidence has been found that multi-symptom relief medicines are inherently less safe than single-active ingredient medicines. Multi-symptom relief combination products containing several active ingredients provide a safe, effective, cost-effective, and convenient way of treating the multiple symptoms of common cold and flu, when used as directed. This therapy requires some special information for the patient to be provided by the physician and the pharmacist.

关键词： Combination Products Multi-Symptom Relief Multi-Ingredient Common Cold Flu

Sleep Medicine in Germany and China–Common Features and Differences

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Sleep Medicine in Germany and China–Common Features and Dif...

The burden of diseases-Insomnia and OSA

中国睡眠研究会第十届全国学术年会

作者： ingo Fietze Thomas Penzel

＜正＞Sleep medicine is not only in China but also in Germany a young medical *** Germany,we have 312 accredited sleep centers and in China,we see about 2400 sleep *** is certainly not *** bigger is the problem,that w...

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The burden of diseases-Insomnia and OSA

中国睡眠研究会第十届全国学术年会

作者： ingo Fietze Thomas Penzel

＜正＞The worldwide challenge in medicine is the increase in obesity and suicide rate,as the medical economists *** study?Global Burden of Disease"mentions the worldwide most common disorders and complaints,but this does not include sleep *** is in contrast to the finding that every second adult person has some degree of sleep disordered

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新型呋喃树脂砂再生系统

铸造技术 2012年第1期33卷 69-71页

作者： ingo Groβ Frank Woldert 德国Niederfischbach市F.A.T.公司

Gusszentrum Ostfriesland（GZO）是风电设备制造商Enercon有限责任公司新建的铸造厂,该厂新建了一套60 T/h的砂再生系统。其设计和施工由F觟rder和Anlagentechnik（FAT）公司完成,F.A.T.

关键词：呋喃树脂砂再生系统设备制造商铸造厂

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Vincent van Gogh 1853-1890

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Vincent van Gogh 1853-1890