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Crushed rocks stabilized with organosilane and lignosulfonate in pavement unbound layers:Repeated load triaxial tests

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Frontiers of Structural and Civil engineering 2021年第2期15卷 412-424页

作者： Diego Maria BARBIeRI inge HOFF Chun-Hsing HO Department of Civil and environmental engineering Norwegian University of Science and TechnologyTrondheimTrøndelag7491Norway Department of Civil and environmental engineering Northern Arizona UniversityFlagstaffAZ86011USA

The creation of the new“Ferry-Free Coastal Highway Route e39”in southwest Norway entails the production of a remarkable quantity of crushed *** resources could be beneficially employed as aggregates in the unbound courses of the highway itself or other road pavements present *** innovative stabilizing agents,organosilane and lignosulfonate,can significantly enhance the key properties,namely,resilient modulus and resistance against permanent deformation,of the aggregates that are excessively weak in their natural *** beneficial effect offered by the additives was thoroughly evaluated by performing repeated load triaxial *** study adopted the most common numerical models to describe these two key mechanical *** increase in the resilient modulus and reduction in the accumulated vertical permanent deformation show the beneficial impact of the ***,a finite element model was created to simulate the repeated load triaxial test by implementing nonlinear elastic and plastic constitutive relationships.

关键词： organosilane lignosulfonate crushed rocks pavement unbound layers repeated load triaxial test finite element analysis

RTP-based broadcast streaming of high definition H.264/AVC video: an error robustness evaluation

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Journal of Zhejiang University-Science A(Applied Physics & engineering) 2006年第Z1期7卷 19-26页

作者： HILLeSTAD Odd inge JeTLUND Ola PeRKIS Andrew Centre for Quantifiable Quality of Service in Communication Systems Norwegian University of Science and Technology Trondheim N-7491Norway

In this work, we present an evaluation of the performance and error robustness of RTP-based broadcast streaming of high-quality high-definition (HD) H.264/AVC video. Using a fully controlled IP test bed (Hillestad et al., 2005), we broadcast high-definition video over RTP/UDP, and use an IP network emulator to introduce a varying amount of randomly distributed packet loss. A high-performance network interface monitoring card is used to capture the video packets into a trace file. Purpose-built software parses the trace file, analyzes the RTP stream and assembles the correctly received NAL units into an H.264/AVC Annex B byte stream file, which is subsequently decoded by JVT JM 10.1 reference software. The proposed measurement setup is a novel, practical and intuitive approach to perform error resilience testing of real-world H.264/AVC broadcast applications. Through a series of experiments, we evaluate some of the error resilience features of the H.264/AVC standard, and see how they perform at packet loss rates from 0.01% to 5%. The results confirmed that an appropriate slice partitioning scheme is essential to have a graceful degradation in received quality in the case of packet loss. While flexible macroblock ordering reduces the compression efficiency about 1 dB for our test material, reconstructed video quality is improved for loss rates above 0.25%.

关键词： H.264/AVC Video streaming error robustness

Current hepatitis B virus infection situation in Indonesia and its genetic diversity

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World Journal of Gastroenterology 2016年第32期22卷 7264-7274页

作者： Maria inge Lusida Juniastuti Yoshihiko Yano Institute of Tropical Disease Airlangga Health Science Institute Airlangga University Department of Microbiology Faculty of Medicine Airlangga University Center for Infectious Diseases Kobe University Graduate School of Medicine

Indonesia has a moderate to high endemicity of hepatitis B virus(HBV) infection. The risk for chronic HBV infection is highest among those infected during infancy. Since 1997, hepatitis B(Hep B) vaccination of newborns has been fully integrated into the National Immunization Program. Al though HBV infection has been reduced by the universal newborn Hep B immunization program, it continues to occur in Indonesia. The low birth dose coverage and the presence of vaccine escape mutants might contribute to this endemicity among children. Although limited information is available for an analysis of occult HBV infection(OBI), several variations and substitutions in the pre-S/S region have been detected in Indonesian HBV strains. Additionally, persistent infection and disease progression of chronic hepatitis B are related to not only viral factors but also the host genome. Indonesia is one of the most ethnically heterogeneous nations, with Javanese and Sundanese as the two highest ethnic groups. This multi-ethnicity makes genomic research in Indonesia difficult. In this article, we focused on and reviewed the following aspects: the current hepatitis B immunization program and its efficacy, OBI, HBV infection among high-risk patients, such as hemodialysis patients, and research regarding the host genome in Indonesia.

关键词： Hepatitis B virus Immunization Occult infection Hemodialysis Indonesia

Legal and ethical Issues in Brain Banking

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Neuroscience Bulletin 2019年第2期35卷 267-269页

作者： inge Huitinga Mignon de Goeij Natasja Klioueva Netherlands Brain Bank Netherlands Institute for Neuro-science Netherlands Royal Academy of Arts and Sciences

The legal and ethical issues in brain banking are *** post-mortem removal and retention of organs as well as research with human tissue and genetic information,have posed various dilemmas in the fields of law and *** to the relative novelty of these issues,the law is often lacking in clear instructions and unambiguous *** ethical problems specifically involving post-mortem cell and tissue banking for research purposes are not always specifically taken into *** means that a brain bank frequently does not qualify for a certain well-defined legal *** of this and the fact that the existing regimes differ significantly throughout the world,many uncertainties arise for the initiation and management of brain *** on informed consent,confidentiality,financial sustainability,accountability,and transparency are conditions sine qua non for the good conduct of a professional brain bank and are briefly highlighted.

关键词： Legal Brain Banking post-mortem

ROCK inhibition as a novel potential strategy for axonal regeneration in optic neuropathies

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Neural Regeneration Research 2015年第12期10卷 1949-1950页

作者： inge Van Hove evy Lefevere Lieve Moons Neural Circuit Development and Regeneration Research Group Department of BiologyKU Leuven Laboratory of Ophthalmology Department of NeurosciencesKU Leuven

Optic neuropathies or optic nerve diseases are a frequent cause of permanent vision loss that can occur after inflammation,ischemia,infection,tumors,trauma and/or an elevated pressure inside the eye（also called intra... 详细信息

关键词： ROCK inhibition as a novel potential strategy for axonal regeneration in optic neuropathies RGCs

Complementary research in mammals and fish indicates MMP-2 as a pleiotropic contributor to optic nerve regeneration

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Neural Regeneration Research 2016年第5期11卷 740-742页

作者： Kim Lemmens inge Van Hove Lieve Moons Neural Circuit Development and Regeneration Research Group Department of BiologyKU Leuven

Matrix metalloproteinases（MMPs）are members of the metzincin superfamily named after the zinc ion and the conserved methionine residue at the active *** addition to their role in extracellular matrix（eCM）remodeling... 详细信息

关键词： MMP Complementary research in mammals and fish indicates MMP-2 as a pleiotropic contributor to optic nerve regeneration MMPs

Oxidative stress drives divergent evolution of the glutathione peroxidase(GPX)gene family in mammals

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Integrative Zoology 2021年第5期16卷 696-711页

作者： Ran TIAN Yuepan GeNG Ying YANG inge SeIM Guang YANG Jiangsu Key Laboratory for Biodiversity and Biotechnology College of Life SciencesNanjing Normal UniversityNanjingJiangsuChina Integrative Biology Laboratory College of Life SciencesNanjing Normal UniversityNanjingJiangsuChina School of Biology and environmental Science Queensland University of TechnologyBrisbaneQueenslandAustralia

The molecular basis for adaptations to extreme environments can now be understood by interrogating the everincreasing number of sequenced *** such as cetaceans,bats,and highland species can protect themselves from oxidative stress,a disruption in the balance of reactive oxygen species,which results in oxidative injury and cell ***,we consider the evolution of the glutathione peroxidase(GPX)family of antioxidant enzymes by interrogating publicly available genome data from 70 mammalian species from all major *** identified 8 GPX subclasses ubiquitous to all mammalian *** GPX gene families resolved into the GPX4/7/8 and GPX1/2/3/5/6 groups and are characterized by several instances of gene duplication and loss,indicating a dynamic process of gene birth and death in *** of the eight GPX subfamilies(all but GPX7)were under positive selection,with the residues under selection located at or close to active sites or at the dimer *** also reveal evidence of a correlation between ecological niches(*** oxidative stress)and the divergent selection and gene copy number of GPX ***,a convergent expansion of GPX1 was observed in several independent lineages of mammals under oxidative stress and may be important for avoiding oxidative ***,this study suggests that the GPX gene family has shaped the adaption of mammals to stressful environments.

关键词： adaptive evolution gene family glutathione peroxidase mammals oxidative stress

evolutionary impacts of purine metabolism genes on mammalian oxidative stress adaptation

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Zoological Research 2022年第2期43卷 241-254页

作者： Ran Tian Chen Yang Si-Min Chai Han Guo inge Seim Guang Yang Jiangsu Key Laboratory for Biodiversity and Biotechnology College of Life SciencesNanjing Normal UniversityNanjingJiangsu 210023China Integrative Biology Laboratory College of Life SciencesNanjing Normal UniversityNanjingJiangsu 210023China School of Biology and environmental Science Queensland University of TechnologyBrisbaneQueensland 4001Australia

Many mammals risk damage from oxidative stress stemming from frequent dives(i.e., cycles of ischemia/reperfusion and hypoxia/reoxygenation),high altitude and subterranean environments, or powered flight. Purine metabolism is an essential response to oxidative stress, and an imbalance between purine salvage and de novo biosynthesis pathways can generate damaging reactive oxygen species(ROS). Here, we examined the evolution of 117 purine metabolism-related genes to explore the accompanying molecular mechanisms of enhanced purine metabolism in mammals under high oxidative stress. We found that positively selected genes,convergent changes, and nonparallel amino acid substitutions are possibly associated with adaptation to oxidative stress in mammals. In particular, the evolution of convergent genes with c AMP and c GMP regulation roles may protect mammals from oxidative damage. Additionally, 32 genes were identified as under positive selection in cetaceans, including key purine salvage enzymes(i.e., HPRT1), suggesting improved re-utilization of non-recyclable purines avoid hypoxanthine accumulation and reduce oxidative stress. Most intriguingly, we found that six unique substitutions in cetacean xanthine dehydrogenase(XDH), an enzyme that regulates the generation of the ROS precursor xanthine oxidase(XO) during ischemic/hypoxic conditions, show enhanced enzyme activity and thermal stability and diminished XO conversion activity. These functional adaptations are likely beneficial for cetaceans by reducing radical oxygen species production during diving. In summary, our findings offer insights into the molecular and functional evolution of purine metabolism genes in mammalian oxidative stress adaptations.

关键词： evolution Mammals Cetaceans Purine metabolism Oxidative stress

Self-Reported Social Status among Rural Residents:A Case in the Outskirts of the Beijing-Tianjin-Hebei Metropolitan Region

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Social Sciences in China 2023年第3期44卷 181-202页

作者： Geir inge Orderud Gu Jintu Luo Jing Norwegian Institute of Urban and Regional Research Oslo Metropolitan University Department of Sociology Hohai University Institute of Chinese Borderland Research Chinese Academy of Social Sciences

China has in recent decades undergone profound changes and continues to do so—changes that are transforming the social fabric,motivating studies on how self-reported social status is changing in different parts of *** a realist approach,the study emanates from theories on self-reported social status underlining the role of reference-groups,adding insights from the work of Pierre Bourdieu by introducing the terminology of habitus and types of ***,the study adds a spatial scale,thereby contributing to theoretical *** the empirical study asked villagers to provide self-reported social status at village,county and national *** statistical analyses include objective and subjective conditions,representing economic,cultural,social,and symbolic capital,as well as other *** results confirm the relevance of the reference-group theory,with self-reported social status decreasing from village to national *** on multivariate analyses,the study identifies two segments of habitus at the village level,one at the county level and one at the national level,facilitating high scores on self-reported social *** habitus segments underline the importance of incorporating spatial scale as a theoretical *** doing so,the study reveals that a habitus segment including cultural capital of farming competence is important at village and county levels but is replaced at the national level by a segment including the social capital of instruction sources related to farming and not wanting to ***,a habitus segment revolving around the economic capital of jobs outside farming,younger generations,and wanting to move is active at the village *** addition to revealing reference-group differences this habitus segment also indicates that large-scale,national transitional forces are at work,facilitating new drivers for self-reported social status locally.

关键词： self-reported social status reference-group theory peri-urban region rural communities farming