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Predictive Factors for Pre-Eclampsia: A Case-Control study in Two Hospitals in Yaounde

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Open Journal of Obstetrics and Gynecology 2024年第4期14卷 565-574页

作者： Junie Annick Metogo Ntsama ines Winnie Gouanfo Claude Hector Mbia Wilfried Loic Tatsipie Pascal Mpono Madye Ngo Dingom Felix Essiben Claude Cyrille Noa Ndoua Faculty of Medicine and Biomedical sciences University of Yaound&#233 I Yaound&#233 Cameroon Faculty of Medicine and Pharmaceutical sciences University of Dschang Dschang Cameroon

Introduction: Pre-eclampsia is a major cause of maternal and prenatal morbidity and mortality, that complicates 2% to 8% of pregnancies worldwide. The aim of this study was to determine the predictive factors for pre-eclampsia in two hospitals in the city of Yaoundé. Methods: A case-control study was conducted at the Gynaecology & Obstetrics department of the Yaoundé Gynaeco-Obstetric and Paediatric Hospital (YGOPH) and the Main Maternity of the Yaoundé Central Hospital (MM-YCH) from February 1 to July 30, 2022. The cases were all pregnant women presenting with pre-eclampsia. The control group included pregnant women without pre-eclampsia. Descriptive statistics followed by logistic regression analyses were conducted with level of significance set at p-value Results: Included in the study were 33 cases and 132 controls, giving a total of 165 participants. The predictive factors for pre-eclampsia after multivariate analysis were: primiparity (aOR = 51.86, 95% CI: 3.01 - 1230.96, p = 0.045), duration of exposure to partner’s sperm Conclusion: The odds of pre-eclampsia increased with primiparity, duration of exposure to partner’s sperm s, personal history of pre-eclampsia and maternal history of pre-eclampsia. Recognition of these predictor factors would improve the ability to diagnose and monitor women likely to develop pre-eclampsia before the onset of disease for timely interventions.

关键词： Pre-Eclampsia Predictive Factors Yaoundé

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A drop of immunity

Molecular Plant 2021年第9期14卷 1437-1438页

作者： ines Trindade Institute for Biochemistry and Biology University of Potsdam14476 PotsdamGermany

Editor's Highlight Molecular Plant snRNA-seq to bulk RNA-seq from whole roots and protoplast suspensions,and captured additional cell subtypes using snRNA-seq that were missed in other published single-cell RNA-seq(scRNA-seq)*** de novo clustering of nuclei based on chromatin accessibility and integration of snATAC-seq with snRNA-seq produced similar clusters,suggesting that the complex Arabidopsis root cellular identities can be revealed by single-nuclei chromatin accessibility profiles(Farmer et al.t 2021).

关键词： immunity roots Arabidopsis

Electrical stimulation and denervated muscles after spinal cord injury

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Neural Regeneration Research 2020年第8期15卷 1397-1407页

作者： subhalakshmi Chandrasekaran John Davis ines Bersch Gary Goldberg Ashraf s.Gorgey spinal Cord Injury and Disorders Hunter Holmes McGuire VA Medical CenterRichmondVAUSA swiss Paraplegic Centre NottwilSwitzerland Institute of Clinical sciences Department of Orthopedics at the University of GothenburgGothenburgSweden Department of Physical Medicine and Rehabilitation Virginia Commonwealth UniversityRichmondVAUSA Electrodiagnostic Center Hunter Holmes McGuire VA Medical CenterRichmondVAUSA

spinal cord injury(sCI)population with injury below T10 or injury to the cauda equina region is characterized by denervated muscles,extensive muscle atrophy,infiltration of intramuscular fat and formation of fibrous *** morphological changes may put individuals with sCI at higher risk for developing other diseases such as various cardiovascular diseases,diabetes,obesity and ***,there is no available rehabilitation intervention to rescue the muscles or restore muscle size in sCI individuals with lower motor neuron ***,hereby,performed a review of the available evidence that supports the use of electrical stimulation in restoration of denervated muscle following *** pulse width stimulation(LPWs)technique is an upcoming method of stimulating denervated *** primary objective is to explore the best stimulation paradigms(stimulation parameters,stimulation technique and stimulation wave)to achieve restoration of the denervated *** parameters,such as the pulse duration,need to be 100–1000 times longer than in innervated muscles to achieve desirable excitability and *** use of electrical stimulation in animal and human models induces muscle *** in animal models indicate that electrical stimulation,with a combination of exercise and pharmacological interventions,have proven to be effective in improving various aspects like relative muscle weight,muscle cross sectional area,number of myelinated regenerated fibers,and restoring some level of muscle *** studies have shown similar outcomes,identifying the use of LPWs as an effective strategy in increasing muscle cross sectional area,the size of muscle fibers,and improving muscle ***,displaying promise is an effective future stimulation *** summary,LPWs is a novel stimulation technique for denervated muscles in humans with *** studies on LPWs of denervated muscles will help in translating

关键词： denervation DXA electrical stimulation LMN injury LPWs MRI spinal cord injury stimulation parameters

Reconstructing f(T) modified gravity from ECHDE and ECNADE models

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Communications in Theoretical Physics 2020年第9期72卷 75-88页

作者： A E Godonou ines G salako M J s Houndjo Etienne Baffou Joel Tossa Institut de Mathematiques et de sciences Physiques(IMsP) 01 BP 613 Porto-NovoBenin Ecole de Genie Rural(EGR) 01 BP 55 KetouBenin Faculte des sciences et Techniques de Natitingou(FAsT) BP 72NatitingouBenin

We investigate alternative candidates to dark energy(DE) that can explain the current state of the Universe in the framework of the generalized teleparallel theory of gravity f(T), where T denotes the torsion scalar. To achieve this, we carry out a series of reconstructions taking into account the ordinary and entropy-corrected versions of the holographic and new agegraphic DE *** models are used as alternatives to DE in the literature in order to describe the current state of our Universe. It is remarked that the proposed models indicate behavior akin to phantom or quintessence models. Furthermore, we also generate the parameters of the equation of state associated with entropy-corrected models and we observe a phase transition between the quintessence state and phantom state as it is shown by the recent observational data. We also investigate the stability of these models and we create the {r-s} trajectories and compare with the ΛCDM limit. The behavior of certain physical parameters such as the speed of sound and the statefinder diagnostic pair {r-s} is compatible with the current observational data.

关键词： teleparallel gravity ECHDE ECNADE

Tanned or sunburned:How Excessive Light Triggers Plant Cell Death

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Molecular Plant 2020年第11期13卷 1545-1555页

作者： stefano D'Alessandro ines Beaugelin Michel Havaux Aix-Marseille University CEACNRSUMR7265BIAMInstitute of Biosciences and Biotechnologies of Aix Marseille13108 Saint-Paul-lez-DuranceFrance singapore-CEA Alliance for Research in Circular Economy(sCARCE) School of Chemical and Biomedical Engineering62 Nanyang DriveSingapore 637459Republic of Singapore

Plants often encounter light intensities exceeding the capacity of photosynthesis(excessive light)mainly due to biotic and abiotic factors,which lower C02 fixation and reduce light energy *** excessive light,the photosynthetic electron transport chain generates damaging molecules,hence leading to photooxidative stress and eventually to cell *** this review,we summarize the mechanisms linking the excessive absorption of light energy in chloroplasts to programmed cell death in plant *** highlight the importance of reactive carbonyl species generated by lipid photooxidation,their detoxification,and the integrating role of the endoplasmic reticulum in the adoption of phototolerance or cell-death ***,we invite the scientific community to standardize the conditions of excessive light treatments.

关键词： Arabidopsis photosynthesis excessive light photooxidative stress carotenoid plant cell death stress response

Computational design in architecture:Defining parametric,generative,and algorithmic design

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Frontiers of Architectural Research 2020年第2期9卷 287-300页

作者： ines Caetano Luis santos Antonio Leitao inesC-ID/Instituto superior Tecnico University of LisbonLisbonPortugal College of Architecture and Environmental Design Kent State UniversityKentUSA

Computation-based approaches in design have emerged in the last decades and rapidly became popular among architects and other *** professionals and researchers adopted different terminologies to address these ***,some terms are used ambiguously and inconsistently,and different terms are commonly used to express the same *** paper discusses computational design(CD)and proposes an improved and sound taxonomy for a set of key CD terms,namely,parametric,generative,and algorithmic design,based on an extensive literature review from which different definitions by various authors were collected,analyzed,and compared.

关键词： Algorithmic design Computer-aided design Computational design Generative design Parametric design

Energy restriction and exercise modulate angiopoietins and vascular endothelial growth factor expression in the cavernous tissue of high-fat diet-fed rats

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Asian Journal of Andrology 2012年第4期14卷 635-642页

作者： ines Tomada Nuno Tomada Henrique Almeida Delminda Neves Department of Experimental Biology Faculty of MedicineUniversidade do Porto--Alameda ProfHernmai MonteiroPorto 4200-319Portugal Instituto de Biologia Molecular e Celular(IBMC) Universidade do Porto--Rua do Campo Alegre 823Porto 4150-180Portugal Department of Urology Centro Hospital S.JoaoEPE-Alameda ProfessorHernmani MonteiroPorto 4200-319Portugal

The purpose of the current study was to evaluate the effect of a high-fat （HF） diet, energy restriction and exercise on the expression of vascular endothelial growth factor （VEGF）, angiopoietin （Ang） I and 2, and their receptors in rat corpus cavernosum （CC）. Male Wistar rats were fed adlibitum with an H F diet for 8 or 16 weeks. After 8 weeks of the H F diet, a group of rats was subjected to energy restriction with or without exercise for 8 weeks. Control animals had free access to standard diet for the same period. After euthanasia, blood was collected and the penises removed for immunofluorescence assays （VEGF, VEGF receptor （VEGFR） I and 2, Angl, Ang2 and Tie2） and semiquantification of VEGF, VEGFR 1, VEGFR2, Angl, Ang2, Tie2, endothelial nitric oxide synthase （eNOs） and Aktlphospho-Akt by Western blotting. HF diet-fed rats exhibited lower high-density lipoprotein cholesterol （HDL-c） levels, higher systolic blood pressure and an increased atherogenic index. A significant increase in Ang2 expression in the CC was verified and coupled to a decrease in VEGF and VEGFRs. The Akt pathway was activated by the HF diet. Energy restriction and exercise increased eNOs expression and restored most HF diet-induced modifications except for VEGFR2 expression. These results emphasize the role of diet on vascular function regulation, demonstrating that cavernous imbalance of VEGF/VEGFRs and Angs/Tie2 systems occurs before serum lipid changes and obesity onset, antedating structural atherosclerotic features.

关键词： angiopoietins corpus cavernosum endothelial dysfunction energy restriction exercise high-fat diet VEGF

Digital representation methods:The case of algorithmic design

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Frontiers of Architectural Research 2022年第3期11卷 527-541页

作者： Renata Castelo-Branco ines Caetano Antonio Leitao inesC-ID/Institute superior Tecnico University of LisbonLisbonPortugal

Architectural representation encompasses the means used to describe architectural *** discipline has long been under constant change due to architects’everpresent desire for *** design(AD)is currently making its way into the plethora of representation methods that integrate the architect’s day-to-day work ***,it provides its fair share of controversy and hardship as it *** paper assesses whether AD is suitable as a representation method for architectural design by making a systematic analysis of this medium as a contemporary representation ***,we investigate(1)its birth and evolution as a means of representation,(2)the characteristics that make it simultaneously appealing and off-putting to the architectural community,(3)the influence of technological evolution and education on its proliferation,and(4)its capacity to represent design problems in comparison to the currently predominant means of digital architectural representation,that is,computer-aided drafting and building information modeling.

关键词： Representation methods Algorithmic design Computer-aided drafting Building information modeling

Hidden Markov Models:Inverse Filtering,Belief Estimation and Privacy Protection

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Journal of systems science & Complexity 2021年第5期34卷 1801-1820页

作者： LOURENCO ines MATTILA Robert ROJAs Cristian R. HU Xiaoming WAHLBERG Bo Division of Decision and Control systems School of Electrical Engineering and Computer ScienceKTH Royal Institute of TechnologyStockholmSweden Division of Optimizations and systems Theory School of Engineering SciencesKTH Royal Institute of TechnologyStockholmSweden

A hidden Markov model(HMM)comprises a state with Markovian dynamics that can only be observed via noisy *** paper considers three problems connected to HMMs,namely,inverse filtering,belief estimation from actions,and privacy enforcement in such a ***,the authors discuss how HMM parameters and sensor measurements can be reconstructed from posterior distributions of an HMM ***,the authors consider a rational decision-maker that forms a private belief(posterior distribution)on the state of the world by filtering private *** authors show how to estimate such posterior distributions from observed optimal actions taken by the *** the setting of adversarial systems,the authors finally show how the decision-maker can protect its private belief by confusing the adversary using slightly sub-optimal *** range from financial portfolio investments to life science decision systems.

关键词： Belief estimation counter-adversarial systems hidden Markov models inverse decision making inverse filtering