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Frontiers of Materials Science 2011年第4期5卷 412-416页

作者： Xiao-Long YU Bin ZHANG Xiu-Mei WANG Ying WANG Lin QIAO Jin HE Juan WANG Shuang-Feng CHEN in-seop lee Fu-Zhai CUI Institute of Regenerative and Biomimetic Materials Department of Materials Science and Engineering Tsinghua University Beijing 100084 China Liaocheng People＇s Hospital Liaocheng 252000 China Atomic-Scale Surface Science Research Center Yonsei University Seou1120-749 Korea

Hepatoma cells （Hepg2s） as typical cancer cells cultured on hydroxyl （-OH） and methyl （- CH3） group surfaces were shown to exhibit different proliferation and morphological changes. Hepg2s cells on OH surfaces grew much more rapidly than those on -CH3 surfaces. Hepg2s cells on -OH surfaces had the larger contact area and the more flattened morphology, while those on CH3 surfaces exhibited the smaller contact area and the more rounded morphology. After 7 days of culture, the migration of Hepg2s cells into clusters on the CH3 surfaces behaved significantly slower than that on the OH surfaces. These chemically modified surfaces exhibited regulation of Hepg2s cells on proliferation, adhesion, and migration, providing a potential treatment of liver cancer.

关键词： chemical groups cell proliferation adhesion migration Hepg2

Frontiers in regenerative medical materials

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Regenerative Biomaterials 2015年第1期2卷 71-76页

作者： Jun Ma Insup Noh in-seop lee Shengmin Zhang Advanced Biomaterials and Tissue Engineering Center Huazhong University of Science and TechnologyWuhan 430074China Department of Chemical and Biomolecular Engineering Seoul National University of Science and TechnologySeoul 139-743 Korea Convergence Institute of Biomedical Engineering and Biomaterials Seoul National University of Science and TechnologySeoul 139-743 Korea Institute of Natural Sciences Yonsei UniversitySeoul 120-749Korea

Based on the last 10 successful series of the China–Korea Symposium on Biomaterials and Nano-biotechnology,we initiated a new invitation-based bilateral forum for established leaders and emerging young scientists in the field,the 2014 China–Korea symposium on biomimetic and regenerative medical materials,which was held from November 26 to 28 in Wuhan,*** the past decade,a lot of breakthrough achievements in biomedical materials and regenerative medicine have been made in our two ***,biomaterials science and engineering has been evolved into a critical stage of bioactive integration and tissue regeneration from a simple functional replacement and *** and regenerative medical materials will become main topics in the field.

关键词： breakthrough initiated regenerative

Characteristics of nonvariceal upper gastrointestinal hemorrhage in patients with chronic kidney disease

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World Journal of Gastroenterology 2013年第43期19卷 7719-7725页

作者： Chang Seok Bang Yong seop lee Yun Hyeong lee Hotaik Sung Hong Jun Park Hyun Soo Kim Jin Bong Kim Gwang Ho Baik Yeon Soo Kim Jai Hoon Yoon Dong Joon Kim Ki Tae Suk Department of Internal Medicine Hallym University College of MedicineChuncheon 200-704South Korea Department of Biology Stanford UniversityStanfordCA 94305United States Department of Internal Medicine Yonsei University Wonju College of MedicineWonju 220-786South Korea

AIM:To evaluate the clinical characteristics of nonvariceal upper gastrointestinal hemorrhage(NGIH)in patients with chronic kidney disease(CKD).METHODS:From 2003 to 2010,a total of 72 CKD patients(male n=52,72.2%;female n=20,27.8%)who had undergone endoscopic treatments for NGIH were retrospectively *** findings,endoscopic features,prognosis,rebleeding risk factors,and mortality-related factors were *** characteristics of the patients and rebleeding-related data were recorded for the following variables:gender,age,alcohol use and smoking history,past hemorrhage history,endoscopic findings(the cause,location,and size of the hemorrhage and the hemorrhagic state),therapeutic options for endoscopy,endoscopist experience,clinical outcomes,and ***:The average size of the hemorrhagic site was 13.7±10.2 mm,and the most common hemorrhagic site in the stomach was the antrum(n=21,43.8%).The most frequent method of hemostasis was combination therapy(n=32,44.4%).The incidence of rebleeding was 37.5%(n=27),and 16.7%(n=12)of patients expired due to *** a multivariate analysis of the risk factors for rebleeding,alcoholism(OR=11.19,P=0.02),the experience of endoscopists(OR=0.56,P=0.03),and combination endoscopic therapy(OR=0.06,P=0.01)compared with monotherapy were significantly related to rebleeding after endoscopic *** a risk analysis of mortality after endoscopic therapy,only rebleeding was related to mortality(OR=7.1,P=0.02).CONCLUSION:Intensive combined endoscopic treatments by experienced endoscopists are necessary for the treatment of NGIH in patients with CKD,especially when a patient is an alcoholic.

关键词： Chronic kidney diseases Gastrointestinal hemorrhage Endoscopy Peptic ulcer Alcoholics

A Hybrid Structure of Dual Stators and a Pneumatic Spring for Resonance Control in an Air Mount

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Journal of Electromagnetic Analysis and Applications 2013年第3期5卷 114-119页

作者： Hyung-Tae Kim Cheol-Ho Kim Sung-Bok Kang Seok-Jun Moon Gyu-seop lee Shock and Vibration Team KIMM DaeJeon South Korea Smart System Research Group KITECH CheonAn South Korea Smart System Research Group KITECH CheonAn South Korea Structure Dynamic Design Group RMS Technology CheonAn South Korea.

An active device using electromagnetic forces was constructed and examined for the purpose of minimizing the resonance in air mounts of clean rooms. The air mounts are vulnerable to low-frequency resonance due to heavy weight and low stiffness. A hybrid structure of the active device, composed of pneumatic and electromagnetic parts, was developed and tested. The pneumatic parts in the device support heavy weights under the air mounts, and the electromagnetic parts reduce the resonance. The electromagnetic parts are composed of dual stators and an armature, which surround the pneumatic parts. The resonance can decrease when electromagnetic forces are generated in the gaps between the stators and the armature. Four active devices were installed under a 3-ton surface plate for a vibration test apparatus. The vibration was detected by eddy-current sensors. Discrete P Control logic was based on displacement, and embedded in a C6713 DSP. The results from impact tests show that the peak magnitude in the resonance frequency can be reduced to –10 dB.

关键词： Low Frequency Resonance Active Vibration Control Pneumatic Spring Air Mount

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射频负偏压等离子体鞘层流体动力学模拟

东北大学学报（自然科学版） 2008年第6期29卷 881-884页

作者：吕少波蔺增巴德纯李麟涉东北大学机械工程与自动化学院辽宁沈阳110004 延世大学物理及应用物理系原子级表面科学中心韩国首尔120-752

采用流体动力学方法建立了一种自洽的无碰撞射频直流偏压等离子体鞘层动力学模型.模型中考虑了极板直流负偏压对离子运动的影响,模拟了在不同偏压条件下射频等离子体鞘层内各参量的时空演化特性.在该模型中,认为鞘层厚度是与时间有关的... 详细信息

采用流体动力学方法建立了一种自洽的无碰撞射频直流偏压等离子体鞘层动力学模型.模型中考虑了极板直流负偏压对离子运动的影响,模拟了在不同偏压条件下射频等离子体鞘层内各参量的时空演化特性.在该模型中,认为鞘层厚度是与时间有关的函数,并采用等效电路模型建立了鞘层瞬时厚度与鞘层电位降的关系.模拟结果表明,极板上电势呈非正弦周期性变化;鞘层厚度变化与极板电势变化周期相同,趋势相反,且略滞后于射频周期.

关键词：射频等离子体直流负偏压无碰撞鞘层流体动力学模型

The Effect of Partial Bladder Outlet Obstruction on Erectile Dysfunction in the Rat Corpus Cavernosum

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The Effect of Partial Bladder Outlet Obstruction on Erectile...

Protective effects of electroacupuncture on acetylsalicylic acid-induced acute gastritis in rats

第十七届全国泌尿外科学术会议

作者： Kyung seop.lee Young Jin Seo Ki Ho Kim Kwangsung Park Department of Urology College of MedicineDongguk University Chonnam National University Hospital

Purposes Erectile dysfunction is a complex neurovascular disease involving vasoconstriction of the corpus cavernosal smooth muscle combined with neuropathy and cavernosal smooth muscle cell ***,I investigated the rela...

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World Journal of Gastroenterology 2009年第8期15卷 973-977页

作者： Hye Suk Hwang Kyung-Ju Han Yeon Hee Ryu Eun Jin Yang Yoo Sung Kim Sang Yong Jeong Young-seop lee Myeong Soo lee Sung Tae Koo Sun-Mi Choi Department of Medica Research Korea Institute of Oriental Medicine Daejeon 305-811 South Korea Division of Meridian and Structural Medicine School of Oriental Medicine Pusan National University Pusan 609-735 South Korea

AIM: To investigate the protective effects of electroacupuncture (EA) pretreatment on acetylsalicylic acid (ASA)-induced ulceration in rats. METHODS: We randomly divided 72 rats into three groups including control (administered with distilled water), ASA group (administered 100 mg/kg ASA) and EA group (administered EA + 100 mg/kg ASA). Each rat was fasted for 18 to 24 h before experimentation, and lesion scores, gastric acidity, cyclooxygenase (COX)-1 and -2 mRNA levels, and total nitric oxide (NO) concentration were measured. RESULTS: The lesion scores of the EA group were significantly lower than those of the ASA group. Gastric acidity of the ASA and EA groups was reduced compared to the control group. COX-1 and -2 mRNA levels were significantly increased in the EA group as compared to the control and ASA groups, and NO levels were also significantly increased in the EA group as compared to the ASA group. CONCLUSION: These results suggest that EA-mediated protection against ASA-induced ulceration in rats may occur via gastric defense components.

关键词： Electroacupuncture Acute gastritis Cyclooxygenase Nitric Oxide

自偏压对PMMA基底上沉积的含氢非晶碳膜的影响(英文)

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自偏压对PMMA基底上沉积的含氢非晶碳膜的影响(英文)

A neural network model for high entropy alloy design

第八届真空冶金与表面工程学术会议

作者：蔺增李明王凤巴德纯 in-seop lee 真空与流体工程研究中心东北大学 Institute of Physics & Applied Physics and Atomic-scale Surface Science Research CenterYonsei UniversitySeoul 120-752

分别用等离子体增强化学气相沉积和磁控溅射的方法在PMMA基底上沉积含氢非晶碳膜和硅膜以应用于生物医学领域。硅膜是用氩离子溅射硅靶制备,而非晶碳膜是以甲烷和氢气为反应气体在不同偏压下制备的。研究发现,所制备的碳膜是包含sp2和sp... 详细信息

分别用等离子体增强化学气相沉积和磁控溅射的方法在PMMA基底上沉积含氢非晶碳膜和硅膜以应用于生物医学领域。硅膜是用氩离子溅射硅靶制备,而非晶碳膜是以甲烷和氢气为反应气体在不同偏压下制备的。研究发现,所制备的碳膜是包含sp2和sp3两种结构的非晶体,与基底材料相比该碳膜在硬度和耐磨性能等方面有明显的提高。结果表明,该非晶碳膜的显微结构、机械和摩擦学特性均显著依赖于薄膜沉积过程中的所用的自偏压。

关键词：非晶碳膜 PMMA 等离子体增强化学气相沉积偏压硬度耐磨损性能

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npj Computational Materials 2023年第1期9卷 1734-1746页

作者： Jaemin Wang Hyeonseok Kwon Hyoung seop Kim Byeong-Joo lee Department of Materials Science and Engineering Pohang University of Science and Technology(POSTECH)Pohang 37673Republic of Korea Graduate Institute of Ferrous and Energy materials Technology(GIFT) Pohang University of Science and Technology(POSTECH)Pohang 37673Republic of Korea Center for Heterogenic Metal Additive Manufacturing Pohang University of Science and Technology(POSTECH)Pohang 37673Republic of Korea Institute for Convergence Research and Education in Advanced Technology Yonsei UniversitySeoul 03722Republic of Korea Advanced Institute for Materials Research(WPI-AIMR) Tohoku UniversitySendai 980-8577Japan

A neural network model is developed to search vast compositional space of high entropy alloys(HEAs).The model predicts the mechanical properties of HEAs better than several other ***’s because the special structure of the model helps the model understand the characteristics of constituent elements of *** addition,thermodynamics descriptors were utilized as input to the model so that the model predicts better by understanding the thermodynamic properties of HEAs.A conditional random search,which is good at finding local optimal values,was selected as the inverse predictor and designed two HEAs using the *** experimentally verified that the HEAs have the best combination of strength and ductility and this proves the validity of the model and alloy design *** strengthening mechanism of the designed HEAs is further discussed based on microstructure and lattice distortion *** present alloy design approach,specialized in finding multiple local optima,could help researchers design an infinite number of new alloys with interesting properties.

关键词： alloy alloys microstructure