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High mobility group box 1 in the central nervous system:regeneration hidden beneath inflammation

Neural Regeneration Research 2025年第1期20卷 107-115页

作者： Hanki Kim Bum Jun Kim Seungyon Koh Hyo Jin cho Xuelian Jin Byung Gon Kim Jun Young choi Department of Brain Science Ajou University School of MedicineSuwonSouth Korea Department of Biomedical Sciences Ajou University Graduate School of MedicineSuwonSouth Korea Department of Neurology Ajou University School of MedicineSuwonSouth Korea Department of Geriatrics The Affiliated Suqian First People’s Hospital of Nanjing Medical UniversitySuqianJiangsu ProvinceChina

High-mobility group box 1 was first discovered in the calf thymus as a DNA-binding nuclear protein and has been widely studied in diverse fields,including neurology and ***-mobility group box 1 in the extracellular space functions as a pro-inflammatory damage-associated molecular pattern,which has been proven to play an important role in a wide variety of central nervous system disorders such as ischemic stroke,Alzheimer’s disease,frontotemporal dementia,Parkinson’s disease,multiple sclerosis,epilepsy,and traumatic brain *** drugs that inhibit high-mobility group box 1 as a damage-associated molecular pattern,such as glycyrrhizin,ethyl pyruvate,and neutralizing anti-high-mobility group box 1 antibodies,are commonly used to target high-mobility group box 1 activity in central nervous system *** it is commonly known for its detrimental inflammatory effect,high-mobility group box 1 has also been shown to have beneficial pro-regenerative roles in central nervous system *** this narrative review,we provide a brief summary of the history of high-mobility group box 1 research and its characterization as a damage-associated molecular pattern,its downstream receptors,and intracellular signaling pathways,how high-mobility group box 1 exerts the repair-favoring roles in general and in the central nervous system,and clues on how to differentiate the pro-regenerative from the pro-inflammatory *** targeting high-mobility group box 1 in the central nervous system may benefit from differentiating between the two functions rather than overall suppression of high-mobility group box 1.

关键词： central nervous system damage-associated molecular pattern ethyl pyruvate glycyrhizzin high mobility group box 1 inflammation neural stem cells neurodevelopment oligodendrocyte progenitor cells redox status regeneration

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Solution‑Processed Thin Film Transparent Photovoltaics:Present Challenges and Future Development

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Nano-Micro Letters 2025年第2期17卷 566-600页

作者： Tianle Liu Munerah M.S.Almutairi Jie Ma Aisling Stewart Zhaohui Xing Mengxia Liu Bo Hou Yuljae cho UM-SJTU Joint Institute Shanghai Jiao Tong UniversityShanghai 200240People’s Republic of China School of Physics and Astronomy Cardiff UniversityCardiff CF243AAWalesUK Department of Electrical and Computer Engineering Yale UniversityNew HavenCT 06511USA Energy Sciences Institute Yale UniversityWest HavenCT 06516USA Future Photovoltaics Research Center Global Institute of Future TechnologyShanghai Jiao Tong UniversityShanghai 200240People’s Republic of China

Electrical energy is essential for modern society to sustain economic *** soaring demand for the electrical energy,together with an awareness of the environmental impact of fossil fuels,has been driving a shift towards the utilization of solar ***,traditional solar energy solutions often require extensive spaces for a panel installation,limiting their practicality in a dense urban *** overcome the spatial constraint,researchers have developed transparent photovoltaics(TPV),enabling windows and facades in vehicles and buildings to generate electric *** TPV advancements are focused on improving both transparency and power output to rival commercially available silicon solar *** this review,we first briefly introduce wavelength-and non-wavelengthselective strategies to achieve *** of merit and theoretical limits of TPVs are discussed to comprehensively understand the status of current TPV *** we highlight recent progress in different types of TPVs,with a particular focus on solution-processed thin-film photovoltaics(PVs),including colloidal quantum dot PVs,metal halide perovskite PVs and organic *** applications of TPVs are also reviewed,with emphasis on agrivoltaics,smart windows and ***,current challenges and future opportunities in TPV research are pointed out.

关键词： Transparent semiconductors Solution-processable transparent solar cell Emerging solar cell materials Buildingintegrated photovoltaics

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GENUS MINIMIZING IN SYMPLECTIC 4-MANIFOLDS

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Chinese Annals of Mathematics,Series B 2000年第1期21卷 115-120页

作者： cho YONGSEUNG cho MISUNG Department of Mathematics Ewha Women’s University Seoul Korea

The authors show that a symplectically embedded surface in a symplectic 4-manifold with hi greater than one minimizes genus in its homology class.

关键词： Generalized Thom Conjecture Seiberg-Witten invariant Symplectic 4-manifolds

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Damage and penetration behavior of aluminum foam at various impacts

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Journal of Central South University 2014年第9期21卷 3442-3448页

作者： cho Hosun cho Jaeung Division of Mechanical Engineering Graduate School Kongju National University Division of Mechanical and Automotive Engineering Kongju National University

In this work, the damage and penetration behavior of aluminum foam at various types of impact were examined through experiments. The impact energy of a striker was applied on the fixed aluminum foam having a thickness of 25 mm while increasing its impact by 2 J at each strike from 6 J to 16 J. The results show that the impact energies from 6 J to 12 J could not penetrate aluminum foam. However, the aluminum foam applied with the impact energy of 12 J incurred severe damages on its lower part. Finally, the aluminum foam applied with the impact energy of 14 J was penetrated. The striker having the impact energy of 6 J could penetrate aluminum foam around 10 mm. At this moment, aluminum foam could absorb the impact energy of around 9 J. When the impact energy of 14 J was applied on the aluminum foam, the aluminum foam was penetrated and it absorbed the impact energy of around 17.2 J. It is possible to create the safer structure against impact using the results of this work. The simulation results for the verification of the experimental results imply that the results for all the experiments in this work are reliable. It is possible to predict the structural safety of the aluminum foam for an impact if the impact behavior of aluminum foam performed in this work is utilized.

关键词： aluminum foam absorbed energy finite element analysis impact energy impact load

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Solution-processing approach of nanomaterials toward an artificial sensory system

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International Journal of Extreme Manufacturing 2024年第5期6卷 1-19页

作者： Okin Song Youngwook cho Soo-Yeon cho Joohoon Kang School of Advanced Materials Science and Engineering Sungkyunkwan University(SKKU)Suwon 16419Republic of Korea School of Chemical Engineering Sungkyunkwan University(SKKU)Suwon 16419Republic of Korea

Artificial sensory systems have emerged as pivotal technologies to bridge the gap between the virtual and real-world,replicating human senses to interact intelligently with external *** practically apply artificial sensory systems in the real-world,it is essential to mass-produce nanomaterials with ensured sensitivity and selectivity,purify them for desired functions,and integrate them into large-area sensory devices through assembly techniques.A comprehensive understanding of each process parameter from material processing to device assembly is crucial for achieving a high-performing artificial sensory *** review provides a technological framework for fabricating high-performance artificial sensory systems,covering material processing to device *** introduce recent approaches for dispersing and purifying various nanomaterials including 0D,1D,and 2D *** then highlight advanced coating and printing techniques of the solution-processed nanomaterials based on representative three methods including(i)evaporation-based assembly,(ii)assisted assembly,and(iii)direct *** explore the application and performances of these solution-processed materials and printing methods in fabricating sensory devices mimicking five human senses including vision,olfaction,gustation,hearing,and tactile ***,we suggest an outlook for possible future research directions to solve the remaining challenges of the artificial sensory systems such as ambient stability,device consistency,and integration with AI-based software.

关键词： artificial sensory system nanomaterials solution-processing printing sensor

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DISTRIBUTIONS ON ALMOST CONTACT MANIFOLDS

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Acta Mathematica Scientia 2017年第3期37卷 695-702页

作者： Hyunjoo cho National Center for Theoretical Sciences Mathematics Division Taipei 10617 China

It is known that any hypersurface in an almost complex space admits an almost contact manifold [11, 14]. In this article we show that a hyperplane in an almost contact manifold has an almost complex structure. Along with this result, we explain how to deter- mine when an almost contact structure induces a contact structure, followed by examples of a manifold with a closed G2-structure.

关键词： Almost contact structure contact structure G2-structure foliation integra-bility

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Efficient Autonomous Defense System Using Machine Learning on Edge Device

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Computers, Materials & Continua 2022年第2期70卷 3565-3588页

作者： Jaehyuk cho School of Electronic Engineering Soongsil UniversitySeoul06978Korea

As a large amount of data needs to be processed and speed needs to be improved,edge computing with ultra-low latency and ultra-connectivity is emerging as a new *** changes can lead to new cyber risks,and should therefore be considered for a security threat *** this end,we constructed an edge system to study security in two directions,hardware and ***,on the hardware side,we want to autonomically defend against hardware attacks such as side channel attacks by configuring field programmable gate array(FPGA)which is suitable for edge computing and identifying communication status to control the communication method according to *** addition,on the software side,data collected on the server performs end-to-end encryption via symmetric encryption ***,we modeled autonomous defense systems on the server by using machine learning which targets to incoming and outgoing *** log utilizes existing intrusion detection datasets that should be used in real-world *** log was used to detect intrusion early by modeling an intrusion prevention system to identify behaviors that violate security policy,and to utilize the existing intrusion detection data set that should be used in a real *** this,we designed an efficient autonomous defense system that can provide a stable system by detecting abnormal signals from the device and converting them to an effective method to control edge computing,and to detect and control abnormal intrusions on the server side.

关键词： Autonomous defense side channel attack intrusion prevention system edge computing machine learning

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Self Localization Method Using Parallel Projection Model for Mobile Sensor in Navigation Applications

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Journal of Computer Science & Technology 2009年第3期24卷 588-603页

作者： Shung Han cho Yuntai Kyong Sangjin Hong We-Duke cho Department of Electrical and Computer Engineering Stony Brook University- SUNY Stony Brook NY U.S.A. Department of Electronics Engineering College of Information Technology Ajou University Suwon Korea

This paper presents a novel self localization method using parallel projection model for mobile sensor in navigation applications. The algorithm estimates the coordinate and the orientation of mobile sensor using projected references on visual image. The proposed method considers the lens non-linearity of the camera and compensates the distortion by using a calibration table. The method determines the coordinates and orientations with iterative process, which is very accurate with low computational demand. We identify various sources of error on the coordinate and orientation estimations, and present both static sensitivity analysis of the algorithm and dynamic behavior of the mobile sensor. The algorithm can be utilized in mobile robot navigation as well as positioning application where accurate self localization is necessary.

关键词： mobile sensors localization parallel projection model visual processing

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Extraction of Behavioural Requirements for Simulation-based Performance Evaluation of Manufacturing Systems

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Journal of Systems Science and Systems Engineering 2019年第5期28卷 555-579页

作者： Junpil Kim Hyunbo cho Department of Industrial and Management Engineering Pohang University of Science and Technology(POSTECH) Republic of Korea

A simulation model enables manufacturers to accurately evaluate the performance of their manufacturing systems.A vital input to build simulation models of manufacturing systems is the system behaviour,which is modelled based on extensive data on manufacturing systems and their ***,for outsourced manufacturing systems,data provided from external suppliers to manufacturers are generally limited and ***,a solution is required to identify and secure system behaviour from available *** propose herein a behaviour extraction process along with detailed activities and diagrams to extract system behaviour from limited *** using the systems engineering standard ANSI/EIA-632,the proposed process systematically restructures available data on a manufacturing system and its elements and then provides complete system behaviour to build a simulation model.A case study on a cooling water control system in a hot strip mill convincingly demonstrates the applicability and effectiveness of the proposed process.

关键词： Behaviour extraction manufacturing systems simulation model system behaviour systems engineering

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Surface-enhanced Raman spectroscopy for emerging contaminant analysis in drinking water

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Frontiers of Environmental Science & Engineering 2023年第5期17卷 51-65页

作者： Seo Won cho Haoran Wei Environmental Chemistry and Technology Program University of Wisconsin–MadisonMadisonWI 53706USA Department of Civil and Environmental Engineering University of Wisconsin–MadisonMadisonWI 53706USA

Emerging contaminants(ECs)in drinking water pose threats to public health due to their environmental prevalence and potential *** occurrence of ECs in our drinking water supplies depends on their physicochemical properties,discharging rate,and susceptibility to removal by water treatment *** health effects of long-term exposure to ECs justify their regular monitoring in drinking water *** this review article,we will summarize the current status and future opportunities of surface-enhanced Raman spectroscopy(SERS)for EC analysis in drinking *** principles of SERS are first introduced and a comparison of SERS and liquid chromatography-tandem mass spectrometry in terms of cost,time,sensitivity,and availability is ***,we discuss the strategies for designing effective SERS sensors for EC analysis based on five categories—per-and polyfluoroalkyl substances,novel pesticides,pharmaceuticals,endocrine-disrupting chemicals,and *** addition to maximizing the intrinsic enhancement factors of SERS substrates,strategies to improve hot spot accessibilities to the targeting ECs are equally *** is a review article focusing on SERS analysis of ECs in drinking *** discussions are not only guided by numerous endeavors to advance SERS technology but also by the drinking water regulatory policy.

关键词： Emerging contaminant Surface-enhanced Raman spectroscopy Drinking water monitoring Sensor Regulatory policy

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