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Neuro-heuristic computational intelligence for solving nonlinear pantograph systems

Frontiers of Information Technology & Electronic Engineering 2017年第4期18卷 464-484页

作者： Muhammad Asif Zahoor RAJA Iftikhar AHMAD imtiaz KHAN Muhammed Ibrahem SYAM Abdul Majid WAZWAZ Department of Electrical Engineering COMSA Ts Institute of Information Technology Attock 43200 Pakistan Department of Mathematics University of Gujrat Gujrat 50700 Pakistan Department of Mathematics Preston University lslamabad Campus Kohat Islamabad 44000 Pakistan Department of Mathematical Scienees United Arab Emirates University Al-Ain Box 15551 UAE Department of Mathematics Saint Xavier University Chicago IL 60655 USA

We present a neuro-heuristic computing platform for finding the solution for initial value problems （IVPs） of non- linear pantograph systems based on functional differential equations （P-FDEs） of different orders. In this scheme, the strengths of feed-forward artificial neural networks （ANNs）, the evolutionary computing technique mainly based on genetic algorithms （GAs）, and the interior-point technique （IPT） are exploited. Two types of mathematical models of the systems are constructed with the help of ANNs by defining an unsupervised error with and without exactly satisfying the initial conditions. The design parameters of ANN models are optimized with a hybrid approach GA-IPT, where GA is used as a tool for effective global search, and IPT is incorporated for rapid local convergence. The proposed scheme is tested on three different types oflVPs of P-FDE with orders 1-3 The correctness of the scheme is established by comparison with the existing exact solutions. The accuracy and convergence ofthc proposed scheme are further validated through a large number of numerical experiments by taking different numbers of neurons in ANN models.

关键词： Neural networks Initial value problems (IVPs) Functional differential equations (FDEs) Unsupervised learning Genetic algorithms (GAs) Interior-point technique (IPT)

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A novel homozygous frameshift variant in DNAH8 causes multiple morphological abnormalities of the sperm flagella in a consanguineous Pakistani family

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Asian Journal of Andrology 2023年第3期25卷 350-355页

作者： Sobia Dil Asad Khan Ahsanullah Unar Meng-Lei Yang imtiaz Ali Aurang Zeb Huan Zhang Jian-Teng Zhou Muhammad Zubair Khalid Khan Shun Bai Qing-Hua Shi Division of Reproduction and Genetics The First Affiliated Hospital of University of Science and Technology of ChinaSchool of Basic Medical SciencesDivision of Life Sciences and MedicineBiomedical Sciences and Health Laboratory of Anhui ProvinceUniversity of Science and Technology of ChinaHefei 230027China

Multiple morphological abnormalities of the sperm flagella(MMAF)is a severe form of asthenozoospermia categorized by immotile spermatozoa with abnormal flagella in ***-exome sequencing(WES)is used to detect pathogenic variants in patients with *** this study,a novel homozygous frameshift variant(c.6158_6159insT)in dynein axonemal heavy chain 8(DNAH8)from two infertile brothers with MMAF in a consanguineous Pakistani family was identified by *** transcription-polymerase chain reaction(RT-PCR)confirmed DNAH8 mRNA decay in these patients with the DNAH8 ***–eosin staining and transmission electron microscopy revealed highly divergent morphology and ultrastructure of sperm flagella in these ***,an immunofluorescence assay showed the absence of DNAH8 and a reduction in its associated protein DNAH17 in the patients'***,our study expands the phenotypic spectrum of patients with DNAH8-related MMAF worldwide.

关键词： DNAH8 gene mutation male infertility multiple morphological abnormalities of the sperm flagella

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Yield and Profit from New and Old Wheat Varieties Using Certified and Farmer-Saved Seeds

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Journal of Agricultural Science and Technology(B) 2016年第3期6卷 141-150页

作者： Krishna Dev Joshi Attiq Ur Rehrnan Ghulam Ullah Amanullah Baloch Makhdoom hussain Javed Ahmad Mohammad Ishaq Gulzar Ahmad Nadeem Abroad Syed Haider Abbas Maqsood Qamar Mumtaz Abroad Abid Ilyas Dar Badar-uddin Khokhar Muhammad Sajid Akhlaq hussain Muhammad imtiaz International Maize and Wheat Improvement Center (CIMMYT) Islamabad 44000 Pakistan Wheat Research Institute Faisalabad 38000 Pakistan Cereal Crops Research Institute Nowshera 24100 Pakistan Barani Agricultural Research Institute Chakwa148800 Pakistan National Agriculture Research Centre lslamabad 44000 Pakistan Engro Fertilizers Limited Lahore 54000 Pakistan Wheat Research Institute Sakrand 67210 Pakistan Pride Seed Company Mardan 23200 Pakistan

Wheat is a strategic crop for food security in Pakistan with predominance of smallholder farmers. Farmer-saved seed （FSS） is used nearly by 75% of farmers for wheat production. Frequent variety or seed replacement is uncommon even among large-scale farmers, and certified seed （CS） is mostly bought to verify the value of new varieties. Replacing old and obsolete varieties by new high yielding disease resistant varieties is key to transferring new genetic gains to farmers. For the first time in Pakistan, on-farm factorial experiments involving seven new and five old wheat varieties and their corresponding CS and FSS were conducted. A total of 49 farmers representing major wheat cropping patterns throughout the country participated in these trials in the 2014 and 2015 wheat growing seasons. Analysis of variance revealed that there was highly significant difference between wheat varieties and between seed classes. New variety ＋ CS gave 33.8% more grain yield as well as higher marginal return over farmers＇ variety ＋ FSS. Grain yield and returns from new variety ＋ FSS and farmers＇ variety ＋ CS were at par. Scientific knowledge generated in this research demonstrated that use of CS ＆new wheat varieties is best option, while growing new varieties with FSS is a second choice for the advantages accruing from their built-in genetic traits of economic importance over growing CS of old and obsolete varieties. Having more flexible seed system will help accelerate the delivery of new genetic gains to farmers＇ fields.

关键词： Certified seed farmer-saved seed variety and seed replacement smallholder farmers yield return varietal popularization.

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Screening for arboviruses in healthy blood donors: Experience from Karachi, Pakistan

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Virologica Sinica 2022年第5期37卷 774-777页

作者： Moiz Ahmed Khan Kehkashan imtiaz Humaira Shafaq Joveria Farooqi Mohammad Hassan Afia Zafar Maureen T.Long Kelli L.Barr Erum Khan Clinical Microbiology Laboratory Department of Pathology&Lab MedicineAga Khan UniversityKarachi 74800Pakistan Blood Bank Haematology&Transfusion MedicineDepartment of Pathology&Lab MedicineAga Khan UniversityKarachi 74800Pakistan Comparative Diagnostic and Population Medicine University of FloridaGainesville FL32611USA Center for Global Health and Infectious Disease Research University of South FloridaTampa FL33620USA

Dear Editor,Arboviruses of medical importance are maintained in nature in enzootic cycles between haematogenous vectors and susceptible vertebrate hosts(Huang et al.,2019).The rapid increase in human populations around the globe and the associated urbanization are creating irreversible damage to the ecosystem,giving rise to many problems including emergence and intensification of the vector borne diseases(Sutherst,2004).Among vector borne diseases,mosquito-borne arboviruses including dengue virus(DENV),West Nile virus(WNV),Japanese Encephalitis virus(JEV)and Zika virus(ZIKV)are rapidly emerging in the affected regions of the world(Palmer et al.,2011).

关键词： maintained irreversible Pakistan

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车轮踏面形状的计算机辅助设计

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国外铁道车辆 1990年第6期27卷 17-20页

作者： imtiaz-ul-Haque 韦苏来

轮轨几何参数通过轮轨间的作用力,对铁道车辆的动力学性能产生极大的影响。本文论述了系统设计车轮踏面形状的计算方法,该方法采用了非线性程序和最优化方法。由此设计的车轮踏面可使车辆获得良好的动力学性能,且能限制磨耗,理论研究说... 详细信息

轮轨几何参数通过轮轨间的作用力,对铁道车辆的动力学性能产生极大的影响。本文论述了系统设计车轮踏面形状的计算方法,该方法采用了非线性程序和最优化方法。由此设计的车轮踏面可使车辆获得良好的动力学性能,且能限制磨耗,理论研究说明了这种计算方法的可行性。

关键词：车轮踏面形状 CAD

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Lady Windermere Syndrome: An Interesting Clinical and Radiological Presentation

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Case Reports in Clinical Medicine 2022年第9期11卷 364-369页

作者： Farid Khan Wajiha Ali Muhammad imtiaz Uzma Sana Ullah Internal Medicine UHS Wilson Medical Center Johnson City USA UHS Pulmonology & Critical Care Wilson Medical Center Johnson City USA

Lady Windermere Syndrome is an uncommon pulmonary disease characteristically observed in elderly white females with chronic cough suppression and dyspnea. It is classically associated with Mycobacterium avium complex (MAC) species. An 84-year-old female was evaluated for longstanding non-productive cough and intermittent dyspnea. A chest computed tomography scan revealed densities in the right upper lobe and scattered nodular-cystic bronchiectasis. Biopsy was negative for malignancy;however, bronchioalveolar lavage studies showed presence of MAC. Patient was treated with a 12-month course of azithromycin, rifampin and ethambutol resulting in resolution of her symptoms.

关键词： Lady Windermere Syndrome Mycobacterium Avium Complex Dyspnea Bronchiectasis

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Recent Insights into Signaling Responses to Cope Drought Stress in Rice

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Rice science 2022年第2期29卷 105-117页

作者： Muhammad Mahran ASLAM Muhammad Abdul Rehman RASHID Mohammad Aquil SIDDIQUI Muhammad Tahir KHAN Fozia FARHAT Shafquat YASMEEN imtiaz Ahmad KHAN Shameem RAJA Fatima RASOOL Mahboob Ali SIAL ZHAO Yan Nuclear Institute of Agriculture Tandojam Sindh 70060Pakistan Department of Bioinformatics and Biotechnology Government College University FaisalabadFaisalabad 38000Pakistan Research Center for Perennial Rice Engineering and Technology in Yunnan School of AgricultureYunnan UniversityKunming 650205China Department of Botany Government College for Women UniversityFaisalabad 38000Pakistan National Center of Bioinformatics Quaid-i-Azam UniversityIslamabad 45320Pakistan State Key Laboratory of Crop Biology Shandong Key Laboratory of Crop BiologyCollege of AgronomyShandong Agricultural UniversityTai’an 271018China

Drought is one of the hot topics needing urgent attention in the current era of climate *** massively disturbs the rice growth and productivity and is becoming a serious *** drought avoidance strategies in rice include stomatal closure,cellular adaptation and changes in root ***,the endogenous plant hormones(abscisic acid and jasmonic acid)and reactive oxygen species have paramount importance in drought tolerance in *** drought tolerance induces modification in biochemical,molecular and physiological properties of *** the molecular level,expression of several transcription-factors is modulated which further determine the activation of drought responsive gene *** activated protein kinases and Ca signaling pathways initiate an array of signaling cascade for mediating the gene expression in ***,conventional breeding methods combined with modern emerging techniques such as genetic engineering,to improve rice drought tolerance were *** review provided recent insights into major regulatory factors against drought stress,signaling mechanisms and molecular engineering strategies(including conventional transgenic and recent genome editing approaches)to induce drought tolerance in rice.

关键词： drought stress rice signaling response regulatory factor

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PAIgG and PAIgM levels in secondary dengue virus infections lead to thrombocytopenia in patients from KP, Pakistan

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Asian Pacific Journal of Tropical Biomedicine 2015年第10期5卷 801-805页

作者： Ibrar Alam Said Hassan Iftikhar Alam Rahmat Gul Farhad AliIjaz Ali Sana Ullah imtiaz Ali Khan Aasif Awan Department of Biotechnology Bacha Khan University Charsadda Institute of Biotechnology and Genetic Engineering(IBGE) The University of Agriculture Center of Biotechnology and Microbiology University of Peshawar Department of Human Nutrition and Dietetics Bacha Khan University Charsadda Department of Zoology University of Peshawar Department of Entomology The University of Agriculture

Objective: To understand the impact of platelet associated immunoglobulin G(PAIg G)/platelet associated immunoglobulin M(PAIg M) on severity of dengue virus infection leading to ***: In this study we examined a total of 52 patients who were having secondary infection of dengue in acute phase by using competitive ***: A decrease in the platelet count was observed at the acute phase of infection while all along the recovery stage the count of platelet was significantly increased. A significant decrease was observed in PAIg G and PAIg M in these subjects. Inverse correlation was found between platelets count and PAIg G/PAIg M among the subjects studied. In the platelets elution from ten subjects, anti-dengue virus immunoglobulin G and immunoglobulin M were observed. PAIg G and PAIg M with inclined levels were higher in dengue hemorrhagic fever than the classical dengue fever. In the development of dengue hemorrhagic fever PAIg M inclined level was independently associated with high specificity, showing a possible indication of dengue hemorrhagic ***: This study suggests that in secondary dengue virus infection, the PAIg G and PAIg M levels, and the activity of anti-dengue virus play key roles, both in the development and severity of the disease.

关键词： dengue Pakistan immunoglobulin hemorrhagic severit

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转基因育种技术在菊花性状改良中的应用进展

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园艺学报 2013年第9期40卷 1813-1825页

作者：成丽娜魏倩 Muhammad imtiaz 高俊平洪波中国农业大学观赏园艺与园林系北京100193

自1989年发现了菊花对农杆菌浸染的敏感性,农杆菌介导转化法已成功应用于菊花花色、花期、株形、抗病虫及耐非生物胁迫等性状的改良中。从影响菊花遗传转化效率的农杆菌菌株类型、外植体选用、辅助添加剂的使用以及抗生素筛选等几方面... 详细信息

自1989年发现了菊花对农杆菌浸染的敏感性,农杆菌介导转化法已成功应用于菊花花色、花期、株形、抗病虫及耐非生物胁迫等性状的改良中。从影响菊花遗传转化效率的农杆菌菌株类型、外植体选用、辅助添加剂的使用以及抗生素筛选等几方面阐述了菊花遗传转化技术研究的进展和应用现状,对菊花分子育种性状改良和重要功能基因发掘等研究进展进行综述,并对菊花转化效率改善途径的探索和环境友好型转基因新技术研发前景提出展望,以期为菊花分子育种提供参考。

关键词：菊花农杆菌转基因分子育种性状改良

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Enhanced 3D Point Cloud Reconstruction for Light Field Microscopy Using U-Net-Based Convolutional Neural Networks

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Computer Systems Science & Engineering 2023年第12期47卷 2921-2937页

作者： Shariar Md imtiaz Ki-Chul Kwon F.M.Fahmid Hossain MdBiddut Hossain Rupali Kiran Shinde Sang-Keun Gil Nam Kim Department of Information and Communication Engineering Chungbuk National UniversityCheongju-siChungcheongbuk-do28644Korea Department of Electronic Engineering University of SuwonHwaseong-siGyeonggi-do18323Korea

This article describes a novel approach for enhancing the three-dimensional(3D)point cloud reconstruction for light field microscopy(LFM)using U-net architecture-based fully convolutional neural network(CNN).Since the directional view of the LFM is limited,noise and artifacts make it difficult to reconstruct the exact shape of 3D point *** existing methods suffer from these problems due to the self-occlusion of the *** manuscript proposes a deep fusion learning(DL)method that combines a 3D CNN with a U-Net-based model as a feature *** sub-aperture images obtained from the light field microscopy are aligned to form a light field data cube for preprocessing.A multi-stream 3D CNNs and U-net architecture are applied to obtain the depth feature fromthe directional sub-aperture LF data *** the enhancement of the depthmap,dual iteration-based weighted median filtering(WMF)is used to reduce surface noise and enhance the accuracy of the *** a 3D point cloud involves combining two key elements:the enhanced depth map and the central view of the light field *** proposed method is validated using synthesized Heidelberg Collaboratory for Image Processing(HCI)and real-world LFM *** results are compared with different state-of-the-art *** structural similarity index(SSIM)gain for boxes,cotton,pillow,and pens are 0.9760,0.9806,0.9940,and 0.9907,***,the discrete entropy(DE)value for LFM depth maps exhibited better performance than other existing methods.

关键词： 3Dreconstruction 3Dmodeling point cloud depth estimation integral imaging light filedmicroscopy 3D-CNN U-Net deep learning machine intelligence

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