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Buerger’s Disease and Fitness for Work in a Flight Personnel: A Case Report

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Occupational Diseases and Environmental Medicine 2022年第2期10卷 71-77页

作者： imen Jammeli Asma Aloui Malek Ben Abdelkader Zeineb Athimni Marwa Bouhoula Chouchene Asma imen kacem Maher Maoua Aicha Brahem Houda Kalboussi Olfa El Maalel Souhaiel Chatti Nejib Mrizak University Hospital Farhat Hached Sousse Tunisia Department of Occupational Medicine University Hospital Ibnou El Jazzar Faculty of Medicine of Sousse University of Sousse Sousse Tunisia

Buerger’s disease, also called thromboangiitis obliterans (TAO), is an inflammatory disease affecting small and medium size blood vessels of the limbs. Several risk factors are strongly associated with this disease. In fact, heavy smokers represent 99% of patients diagnosed with Buerger’s disease and smoking cessation can slow down the progression of the pathology. Ulcers and gangrene are very common complications and TAO may also cause a vasculitis as well as ischemic damage to the distal part of the limbs that can eventually lead to limb amputation. Here, we report the case of a 43 years old patient, a flight personnel working in a Tunisian airline company who consults for a lesion of the left toe that appeared 2 weeks ago. He is a chronic inveterate smoker with 36 pack-years. The diagnosis of TAO was made based on the clinical presentation and the results of the Doppler Ultrasound of the left toe. This disease has a major impact on the quality of life due to the risk of necrotic ulcers and amputation. Navigation is a profession that requires a high level of physical and mental fitness. According to the international and Tunisian standards, the applicant or the holder of medical certificate must not have a cardiovascular condition that may affect the safety of the exercise.

关键词： Buerger’s Disease Flight Personnel Medical Fitness

Monitoring of hepatocellular carcinoma

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World Journal of Gastroenterology 2024年第8期30卷 991-993页

作者： imen Akkari Hanen Jaziri Department of Gastroenterology University Hospital of HachedUniversity of SousseFaculty of Medicine of SousseSousse 4000Tunisia Department of Gastroenterology University Hospital of SahloulUniversity of SousseFaculty of Medicine of SousseSousse 4054Tunisia

Screening for hepatocellular carcinoma in patients at risk is an evidence-based approach;however,adherence to the monitoring protocol recommended by international guidelines is ***,there is a need to use the best scre... 详细信息

关键词： Hepatocellular carcinoma Cirrhosis Risk factors Surveillance Imaging Diagnosis

Impact of prenatal,neonatal,and postnatal factors on epilepsy risk in children and adolescents:a systematic review and meta-analysis

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Acta Epileptologica 2024年第1期7卷 21-35页

作者： imen Ketata Emna Ellouz Rahil Mizouri Neurology Department University Hospital of GabesGabes6014Tunisia Sfax University Sfax3029Tunisia Monastir University Monastir5000Tunisia

Background Epilepsy is a common,long-term neurological *** previous case-control,cohort and cross-sectional studies have highlighted the role of prenatal,delivery and postnatal factors in the onset of *** this systematic review,we evaluate the impact of these factors on the development of epilepsy in children and *** We searched PubMed and Google Scholar for literature on the relationship between prenatal,delivery and postnatal factors and the occurrence of *** research was performed according to the PRSIMA 2020 flowchart and *** were extracted and pooled according to the ReviewManager 5.3 software using a random-effects *** analysis and subgroup analysis were used to evaluate the source of *** We identified 25 reports,including 45,044 cases with confirmed epilepsy and 2,558,210 *** birth is significantly associated with the risk of epilepsy(pooled OR=4.36[95%CI:1.26–15.09],P=0.02).Smoking during pregnancy significantly increases this risk by 28%(pooled OR=1.28[95%CI:1.1–1.49],P=0.002).Furthermore,maternal epilepsy confers a pooled OR of 2.06[95%CI:1.26–3.36].Eclampsia is linked to a 16.9-fold increased risk of *** addition,both pregnancy metrorrhagia and maternal infection are significantly associated with the epilepsy risk(pooled OR=2.24[95%CI:1.36–3.71]and 1.28[95%CI:1.17–1.41],respectively).For delivery conditions,cord prolapse(pooled OR=2.58[95%CI:1.25–5.32]),prolonged labor(>6 h)(OR=6.74[95%CI:3.57–12.71])and head trauma(pooled OR=2.31[95%CI:1.54–3.48])represent a meaningful risk of epilepsy ***,birth complications(OR=3.91[95%CI:2.43–6.29]),low birth weight(pooled OR=1.83[95%CI:1.5–2.23])and male birth(pooled OR=1.18[95%CI:1.06–1.32])are associated with an elevated risk of epilepsy in childhood and *** Epilepsy in children and adolescents can be attributed to a multitude of intricate factors,notably those during p

关键词： Prenatal factors Delivery factors Postnatal factors Epilepsy Children Adolescents

In vitro engineered models of neurodegenerative diseases

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BIOCELL 2024年第1期48卷 79-96页

作者： ZEHRA GÜL MORÇimen ŞEYMA TAŞDEMIR AYLIN ŞENDEMIR Bioengineering Department Graduate School of Natural and Applied SciencesEge UniversityIzmir35040Türkiye Bioengineering Department Faculty of Engineering and Natural ScienceCelal Bayar UniversityManisa45110Türkiye Bioengineering Department Ege UniversityIzmir35040Türkiye Department of Biomedical Technologies Graduate School of Natural and Applied SciencesEge UniversityIzmir35040Türkiye

Neurodegeneration is a catastrophic process that develops progressive damage leading to functional andstructural loss of the cells of the nervous system and is among the biggest unavoidable problems of our *** do not reflect the pathophysiology observed in humans due to distinct differences between the neuralpathways,gene expression patterns,neuronal plasticity,and other disease-related mechanisms in animals *** in vitro cell culture models are also not sufficient for pre-clinical drug testing in reflecting thecomplex pathophysiology of neurodegenerative ***,modern,engineered techniques are applied to developmulticellular,intricate in vitro models and to create the closest microenvironment simulating biological,biochemical,and mechanical characteristics of the in vivo degenerating *** THIS review,the capabilities and shortcomings ofscaffold-based and scaffold-free techniques,organoids,and microfluidic models that best reflect neurodegeneration invitro in the biomimetic framework are discussed.

关键词： Neurodegenerative diseases In vitro models Scaffolds Organoids Microfluidic devices

Analysis and Control of the Vehicle Roll Dynamics Using Sum of Squares Polynomial Approach

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Journal of Systems Science & Complexity 2024年

作者： IBEN AMMAR imen DOUMIATI Moustapha TALJ Reine CHOKOR Abbas MACHMOUM Mohamed ESEO-IREENA Institut de Recherche en énergie électrique de Nantes Atlantique IREENA UR 4642 37 Boulevard de l’Université-BP406 Sorbonne Universités Université de Technologie de Compiègne CNRS Institut de Recherche en énergie électrique de Nantes Atlantique IREENA UR 4642 37 Boulevard de l’Université-BP 406

The safety of vehicle travel relies on good stability performance, making vehicle motion control a vital technology in vehicles. This paper focuses on investigating the impact of roll control on vehicle performance, particularly in terms of avoiding rollover and ensuring lateral stability. By introducing a feedback roll moment, the roll motion can be effectively controlled. The paper considers two roll reference generators: A static one aimed at zero roll, and a dynamic one based on the vehicle's lateral acceleration. The static roll reference generator enhances stability by employing a fixed reference, particularly beneficial during routine driving conditions. In contrast, the dynamic roll reference generator continually adapts the roll angle reference in response to real-time vehicle dynamics and driving conditions. These proposed reference generators can be paired with varying suspension systems — Static reference could be achieved using semi-active suspensions, while the dynamic one is integrated into advanced active suspension systems, offering heightened adaptability and *** address the roll control objectives, this paper proposes a novel sum of squares(SOS) integral polynomial tracking control. The proposed controller satisfies control bounds and considers control constraints during the design phase. The effectiveness and robustness of the proposed control scheme are evaluated through numerical simulations using a full vehicle nonlinear model in Matlab/Simulink. The results of these simulations are compared to super-twisting sliding mode and Lyapunov-based controllers.

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Design and initial testing of a maize cob collection system

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International Journal of Agricultural and Biological Engineering 2024年第3期17卷 108-114页

作者： Bojan Dolšak Anita Breznik Klemen Kaučič Nataša imenšek Marko Marčec Peter Gselman Jani Humar Mitja Krajnc University of Maribor Faculty of Mechanical EngineeringSmetanova ulica 172000 MariborSlovenia ŽIPO Lenart Ltd. Šetarova 212230 LenartSlovenia KGS Krajnc Ltd Vinička vas 42230 LenartSlovenia Interkorn Ltd. Gančani 949231 BeltinciSlovenia

Maize cobs are valuable plant residues that can be used for many different purposes,including as a renewable energy *** their value,maize cobs are still underutilized,mainly because people are not aware of their potential and harvesting techniques for their collection are still being ***,this research focused on finding the most suitable energy-and time-efficient method for mechanical collection of maize *** the combine harvester with an additional hopper proved to be the most promising solution,as it allows harvesting and storage of maize grain and maize cobs in one pass,while the harvesting time remains almost the same and the maize cobs are of good quality,as they do not fall on the field.A prototype with enlarged openings in the straw walkers,an additional grab container for maize cobs,a transport auger,a transport cleaning fan with built-in knives,a transport tube and some other assemblies was fabricated and used in *** first test results are very encouraging(94.4%-96.0%purity of maize cobs)and the system has been patented as a promising solution,especially in times when the environmental sustainability of the planet and energy independence are becoming increasingly important.

关键词： maize cobs utilization mechanical harvesting combine harvester upgrade

Epidemiological and histopathological characteristics of thyroid carcinoma in a Tunisian health care center

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World Journal of Otorhinolaryngology-Head and Neck Surgery 2024年第1期10卷 37-42页

作者： Maissa Ben Thayer Fatma Khanchel imen Helal Dorra Chiboub Hedhli Raoueh Ehsen Ben Brahim Raja Jouini Aschraf Chadli-Debbiche Faculty of Medicine of Tunis Tunis El Manar UniversityTunisTunisia Depatment of Pathology Habib Thameur's HospitalTunisTunisia Department of Otorhinolaryngology-Head and Neck surgery Habib Thameur's HospitalTunisTunisia

Background:Thyroid carcinoma(TC)accounts for almost 0.5%–1%of total *** incidence is increasing rapidly *** studies have drawn up the epidemiological profile of TC and its clinical and pathological ***,to date,no similar studies have been conducted in ***:To establish an epidemiological profile of TC in a Tunisian health care institute and to analyze its clinical and histopathological characteristics in our *** and Methods:We present a retrospective study reviewing the cases of TC diagnosed in our institution in a 4-year ***:We collected a sample of 192 cases of *** consisted of 31 males and 161 females(83.8%)with a sex-ratio M/F of *** mean age was 46.4 *** thyroid carcinoma was the most frequent histological *** multifocality rate was 33.8%.The mean size of TC was 2.2±1.9 cm.60.9%of TC were staged pT1 and 20.3%had nodal *** thyroid microcarcinomas were noted in 37.5%of ***:Our results were consistent with those of the literature.A high proportion of pT1 and pN0 tumors were noted in our series,suggesting that TC's diagnosis and management was performed at an early stage of the disease in our *** addition,our study enabled us to notice the impact of the Coronavirus disease 19 crisis on the management of TC in our *** studies are needed to establish the epidemiological profile of TC in Tunisia and to assess its clinical and pathological features.

关键词： coronavirus disease 19 epidemiology papillary thyroid carcinoma papillary thyroid microcarcinoma pathology thyroid carcinoma

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Global Practical Exponential Stabilization for One-Sided Lipschitz Systems with Time Delay

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Journal of Systems Science & Complexity 2022年第6期35卷 2029-2045页

作者： imen Akrouti NADHEM Echi Faculty of Sciences of Sfax Department of MathematicsSfax UniversityBP1171 Sfar 3000Tunisia Faculty of Sciences of Gafsa Department of MathematicsGafsa UniversityZarroug Gafsa 2112Tunisia

This paper addresses the practical stabilization problem for a class of one-sided Lipschitz nonlinear time delay systems with external *** case there is no perturbation,the exponential convergence of the observer was *** external disturbances appear in the system,a separation principle is established,and the authors show that the closed loop system is exponentially practical *** choosing a suitable Lyapunov-Krasovskii functional,the authors derive new sufficient conditions to guarantee the exponential stability of the ***,a physical model is performed to prove the efficiency and applicability of the suggested approach.

关键词： Lyapunov-Krasovskii nonlinear time-delay systems one-sided Lipschitz condition separation principle

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Characterization of Tunisian marine sediments in Rades and Gabes harbors

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International Journal of Sediment Research 2014年第3期29卷 391-401页

作者： imen BEL HADJ ALI Zoubeir LAFHAJ Mounir BOUASSIDA imen SAID Ecole Centrale de Lille Villeneuve d'AscqFrance and Ecole Nationale d'Ingenieurs de TunisTunisia Ecole centrale de Lille Villeneuve d'AscqFrance Universite de Tunis El Manar/Ecole Nationale d'Ingenieurs de Tunis/05-UR-11 06 Universite de Tunis El Manar/Ecole Nationale d'Ingenieurs de Tunis/05-UR-1106

The objective of this article is to study the geotechnical and environmental characteristics of sediments dredged from two Tunisian harbors:Rades and *** first harbor represents the main facility place in the national transport *** second one is selected as its sediments present a serious ecological constraint caused by the discharge of wastes into the marine *** sediments are either discarded at sea or landfilled despite their harmful effects on the *** article is divided into three main *** first one presents the material that was carried for Rades and Gabes *** conservation conditions and the used experimental tests are *** characterization includes the determination of the grain size distribution,the water content,the Atterberg limits,the methylene blue value,the specific area,the bulk density,the specific unit weight,the organic and carbonate *** characterization is assessed by the determination of metals concentrations in a leaching *** second section deals with the description and analysis of geotechnical properties of Rades and Gabes harbors’ *** results obtained show that Rades harbor sediments are slightly sandy clayey silts whereas Gabes harbor sediments are silty sands characterized by a highly plastic clay *** of the two sediments don’t exhibit a high organic ***,chemical,mineralogical and environmental properties are presented and then *** experimental results obtained show that Rades and Gabes sediments could be used as a sand substitute in the formulation of a new construction *** harbor sediments are more polluted than Rades harbor sediments.

关键词： Sediments Characterization Geotechnical Environmental Valorization