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NEURo FUZZY MoDEL FoR PREDICTING THE DYNAMIC CHARACTERISTICS oF BEAMS

Acta Mechanica Solida Sinica 2014年第1期27卷 85-96页

作者： imad o.bachi Nabeel Abdulrazzaq Zeng He Department of Mechanical Engineering Basrah University Department of Mechanics Engineering Huazhong University of Science and Technology Department of Civil Engineering Basrah University

An adaptive neuro-fuzzy inference system （ANFIS） is introduced to predict the dynamic behavior of beams. The effects of axial forces and large displacements are considered in the analysis. A database of tests for the dynamic characteristics of beams is developed from the experimental tests. The responses of nonlinear vibration force for the single and multiple-stepped beams are calculated from the finite element method （FEM）, experimental tests and neuro-fuzzy model for comparison. The neuro-fuzzy model provides a general framework for the combination of neural networks and fuzzy logic. It is more flexible with more options of incorporating the fuzzy nature of the real-world system and is an useful estimation tool for the dynamic characteristics of beams. Therefore, ANFIS can be a useful tool for dynamic behaviour analysis of multiple-stepped beams subjected to axial loads and large displacement.

关键词： dynamic analysis large displacement neuro-fuzzy finite element beam

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Galectin-3 expression favors metastasis in murine melanoma

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Advances in Bioscience and Biotechnology 2013年第10期4卷 55-62页

作者： Andreia Neves Comodo Andre Luis Lacerda bachi Maria Fernanda Soares Marcello Franco Vicente de Paulo Castro Teixeira Departamento de Patologia Universidade Federal de Sao PauloSao PauloBrasil Departamento de Microbiologia Imunologia e ParasitologiaUniversidade Federal de Sao PauloSao PauloBrasil

Galectin-3 is a member of the lectin family that binds β-galactosides and plays an important role in several types of tumors. Melanoma is an invasive cancer responsible for 80% of deaths associated to skin cancers. There are some evidences that galectin-3 interacts with β-catenin, a molecule involved with Wnt signaling pathway. Here, we evaluate the role of galectin-3 intumor growth and metastasis, as well as its interaction with β-catenin. Murine melanoma cells (B16F10) were injected subcutaneously and intravenously in male C57BL/6 wild-type (WT) and galectin-3 knock-out (Ko) mice. Tumor growth and lung melanoma colonies were assessed. The expression of galectin-3 and β-catenin was evaluated by immuno-histochemistry. We observed that tumor growth did not differ between the groups. However, to metastasis, the number of lung colonies in WT mice was significantly increased in comparison to that observed in Ko mice. The cytoplasm expression of galectin-3 was observed in subcutaneous and metastatic tumors,w in both groups. We observed its nuclear expression in some of subcutaneous tumors of Ko mice. The expression of β-catenin was detected in cell membrane of all subcutaneous tumors analyzed, whereas in the metastatic tumors we observed both cytoplasm and cell membrane staining. Altogether, our data suggest that galectin-3 favors the metastasis of melanoma cells and this process is not associated with β-catenin.

关键词： Melanoma Galectin-3 Wnt Signaling β-Catenin Metastasis

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Imaging plaque inflammation in asymptomatic cocaine addicted individuals with simultaneous positron emission tomography/magnetic resonance imaging

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World Journal of Radiology 2019年第5期11卷 62-73页

作者： Keren bachi Venkatesh Mani Audrey E Kaufman Nadia Alie Rita Z Goldstein Zahi A Fayad Nelly Alia-Klein Department of Psychiatry Icahn School of Medicine at Mount SinaiOne Gustave L.Levy PlaceNew YorkNY 10029United States Department of Environmental Medicine and Public Health Icahn School of Medicine at Mount SinaiOne Gustave L.Levy PlaceNew YorkNY 10029United States Translational and Molecular Imaging Institute Icahn School of Medicine at Mount SinaiOne Gustave L.Levy PlaceNew YorkNY 10029United States Children's Hospital of Philadelphia 3401 Civic Center BlvdPhiladelphiaPA 19104United States Department of Neuroscience Icahn School of Medicine at Mount SinaiOne Gustave L.Levy PlaceNew YorkNY 10029United States

BACKGRoUND Chronic cocaine use is associated with stroke, coronary artery disease and myocardial infarction, resulting in severe impairments or sudden mortality. In the absence of clear cardiovascular symptoms, individuals with cocaine use disorder (iCUD) seeking addiction treatment receive mostly psychotherapy and psychiatric pharmacotherapy, with no attention to vascular disease (i.e., atherosclerosis). Little is known about the pre-clinical signs of cardiovascular risk in iCUD and early signs of vascular disease are undetected in this underserved population. AIM To assess inflammation, plaque burden and plaque composition in iCUD aiming to detect markers of atherosclerosis and vascular disease. METHoDS The bilateral carotid arteries were imaged with positron emission tomography/magnetic resonance imaging (PET/MRI) in iCUD asymptomatic for cardiovascular disease, healthy controls, and individuals with cardiovascular risk. PET with 18F-fluorodeoxyglucose (18F-FDG) evaluated vascular inflammation and 3-D dark-blood MRI assessed plaque burden including wall area and thickness. Drug use and severity of addiction were assessed with standardized instruments. RESULTS The majority of iCUD and controls had carotid FDG-PET signal greater than 1.6 but lower than 3, indicating the presence of mild to moderate inflammation. However, the MRI measure of wall structure was thicker in iCUD as compared to the controls and cardiovascular risk group, indicating greater carotid plaque burden. iCUD had larger wall area as compared to the healthy controls but not as compared to the cardiovascular risk group, indicating structural wall similarities between the non-control study groups. In iCUD, wall area correlated with greater cocaine withdrawal and craving. CoNCLUSIoN These preliminary results show markers of carotid artery disease burden in cardiovascular disease-asymptomatic iCUD. Broader trials are warranted to develop protocols for early detection of cardiovascular risk and prevent

关键词： 3-D dark-blood magnetic resonance imaging 18F-fluorodeoxyglucose positron emission tomography Simultaneous positron emission tomography Magnetic resonance Substance use disorder Cocaine addiction Atherosclerosis Plaque burden Vascular inflammation

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改善法国图卢兹自来水厂沉淀池出水水质的实验研究

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净水技术 2006年第6期25卷 46-50页

作者：陶凌夏玉龙刘凡清 Abdel Christian Bazer-bachi 同济大学环境科学与工程学院上海200092 淮安锦纶化纤有限公司江苏淮安223200 上海凡清环境工程有限公司上海200942 法国威立雅集团西南地区净水处理技术总监

法国图卢兹市的Pech-David自来水厂所用处理工艺中的cyclofloc沉淀池出水浊度过高(2．3NTU,该市另一个水厂平流沉淀池的出水浊度0．5NTU),为了寻找试剂来改善该浊度问题,结合来自Floerger以及Ciba公司的混凝剂与助凝剂,进行混凝实验。... 详细信息

法国图卢兹市的Pech-David自来水厂所用处理工艺中的cyclofloc沉淀池出水浊度过高(2．3NTU,该市另一个水厂平流沉淀池的出水浊度0．5NTU),为了寻找试剂来改善该浊度问题,结合来自Floerger以及Ciba公司的混凝剂与助凝剂,进行混凝实验。实验对有机凝聚剂从:效率、投加顺序以及节省无机凝聚剂投加量三个方面来研究。通过实验,发现某几种阳离子有机凝聚剂能够改善沉淀出水水质,但试剂以及投加设备的费用较高。对于阴离子助凝剂,实验以观察试剂效果和确定最佳投加量为目的,其中6种试剂效果较好,建议在水厂试用,以确定它们的实际效果。

关键词：混凝实验凝聚剂助凝剂 cyclofloc 浊度

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更年期的印度

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东方企业家 2007年第11期 110-110页

作者： bachi Karkaria

更年期不是抑郁和低潮，而是解脱束缚的到来。在这个阶段，她不需要过多担心。放开手去做好了。

关键词：更年期印度硅谷经济发展社会发展建国60周年

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