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Journal of Geoscience and Environment Protection 2017年第5期5卷 1-13页

作者： Khadija Diani Hassan Tabyaoui ilias Kacimi Fatima El Hammichi Chafik Nakhcha LO3G Laboratory Department of Earth Sciences Faculty of Sciences Mohammed V-Agdal University Rabat Morocco Natural Ressources and Environnement Laboratory Polydisciplinary Faculty of Taza Sidi Mohamed Ben Abdellah University Fez Morocco Polydisciplinary Faculty of Safi Cadi Ayyad University Marrakech Morocco

This paper discusses the integration between GIS and hydrological models and presents a case study relating to the upper section of Moulouya River Basin (UMRB) situated in the east of Morocco. The Basin is an inland water-shed with a total area of approximately 10,000 km2, stretching in the junction between the Middle Atlas, the High Atlas Mountain and the Middle Moulouya basin. From ArcGIS ArcHydro framework data models, different parameters of the Moulouya River and its catchment area have been defined. DEM based ArcHydro model was run on Aster-GDEM V2 data at a horizontal spatial resolution of 30 meters. Several raster and vector products of the Upper Moulouya River and its catchment area have been defined at the end of the model. Final results of the models were discussed and compared with the reality. These results can be used in baseline for advanced hydrology and geomorphology research on the catchment area. They can support for decision-making on ground and surface water resource, distribution and management.

关键词： Hydrological Modelling Aster-GDEM V2 ArcHydro Upper Moulouya Basin East Morocco

Effects of an active lifestyle on the physical frailty of liver transplant candidates

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World Journal of Transplantation 2022年第11期12卷 365-377页

作者： ilias Marios Oikonomou Emmanouil Sinakos Nikolaos Antoniadis Ioannis Goulis Olga Giouleme Maria Anifanti Georgios Katsanos Konstantina-Eleni Karakasi Georgios Tsoulfas Evangelia Kouidi Department of Transplant Surgery Aristotle University of ThessalonikiThessaloniki 54642Greece The Fourth Department of Internal Medicine Aristotle University of ThessalonikiThessaloniki 54642Greece The Second Propaedeutic Department of Internal Medicine Aristotle University of ThessalonikiThessaloniki 54642Greece Laboratory of Sports Medicine Aristotle University of ThessalonikiThessaloniki 57001Greece

BACKGROUND Liver transplantation is the most important therapeutic intervention for end-stage liver disease(ELD).The prioritization of these patients is based on the model for end-stage liver disease(MELD),which can successfully predict short-term ***,despite its great validity and value,it cannot fully incorporate several comorbidities of liver disease,such as sarcopenia and physical frailty,variables that can sufficiently influence the survival of such ***,there is growing interest in the importance of physical frailty in regard to mortality in liver transplant candidates and recipients,as well as its role in improving their survival *** To evaluate the effects of an active lifestyle on physical frailty on liver transplant *** An observational study was performed within the facilities of the Department of Transplant Surgery of Aristotle University of *** liver transplant candidate patients from the waiting list of the department were included in the *** that were bedridden,had recent cardiovascular incidents,or had required inpatient treatment for more than 5 d in the last 6 mo were excluded from the *** following variables were evaluated:Activity level via the International Physical Activity Questionnaire(IPAQ);functional capacity via the 6-min walking test(6MWT)and cardiopulmonary exercise testing;and physical frailty via the Liver Frailty Index(LFI).RESULTS According to their responses in the IPAQ,patients were divided into the following two groups based on their activity level:Active group(A,10 patients);and sedentary group(S,10 patients).Comparing mean values of the recorded variables showed the following results:MELD(A:12.05±5.63 vs S:13.99±3.60;P>0.05);peak oxygen uptake(A:29.78±6.07 mL/kg/min vs S:18.11±3.39 mL/kg/min;P<0.001);anaerobic threshold(A:16.71±2.17 mL/kg/min vs S:13.96±1.45 mL/kg/min;P<0.01);6MWT(A:458.2±57.5 m vs S:324.7±55.8 m;P<0.001);and LFI(A:3.75±0.31 vs

关键词： Liver transplantation Frailty Six-minute walk test Cardiopulmonary exercise testing Exercise therapy Observational study

Subclinical peritonitis due to perforated sigmoid diverticulitis 14 years after heart-lung transplantation

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World Journal of Gastroenterology 2008年第22期14卷 3583-3586页

作者： Haridimos Markogiannakis Manousos Konstadoulakis Dimitrios Tzertzemelis Pantelis Antonakis ilias Gomatos Constantinos Bramis Andreas Manouras 1st Department of Propaedeutic Surgery Hippokration Hospital Athens Medical School University of Athens Vasilissis Sofias 114 Avenue Athens 11527 Greece

Acute complicated diverticulitis, particularly with colon perforation, is a rare but serious condition in transplant recipients with high morbidity and mortality. Neither acute diverticulitis nor colon perforation has been reported in young heart-lung grafted patients. A case of subclinical peritonitis due to perforated acute sigmoid diverticulitis 14 years after heart-lung transplantation is reported. A 26-year-old woman, who received heart-lung transplantation 14 years ago, presented with vague abdominal pain. Physical examination was normal. Blood tests revealed leukocytosis. Abdominal X-ray showed air-fluid levels while CT demonstrated peritonitis due to perforated sigmoid diverticulitis. Sigmoidectomy and end-colostomy (Hartmann's procedure) were performed. Histopathology confirmed perforated acute sigmoid diverticulitis. The patient was discharged on the 8th postoperative day after an uneventful postoperative course. This is the first report of acute diverticulitis resulting in colon perforation in a young heart-lung transplanted patient. Clinical presentation, even in peritonitis, may be atypical due to the masking effects of immunosuppression. A high index of suspicion, urgent aggressive diagnostic investigationof even vague abdominal symptoms, adjustment of immunosuppression, broad-spectrum antibiotics, and immediate surgical treatment are critical. Moreover, strategies to reduce the risk of this complication should be implemented. Pretransplantation colon screening, prophylactic pretransplantation sigmoid resection in patients with diverticulosis, and elective surgical intervention in patients with nonoperatively treated acute diverticulitis after transplantation deserve consideration and further studies.

关键词： Heart-lung transplantation Acute diverticulitis Colon perforation Subclinical peritonitis

Application of Trichoderma harzianum in the control of basal stem rot of oil palms

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浙江大学学报（农业与生命科学版） 2004年第4期30卷 391-391页

作者： Abdullah F ilias G N M Department of Biology Faculty of Science and Environmental Studies43400 Serdang Selangor Malaysia Department of Biology Faculty of Science and Environmental Studies43400 Serdang Selangor Malaysia

The palm, Elaeis guineensis, has its origins in Africa but is planted on a commercial basis in several countries. Statistics for 2002 showed that in the lead for land mass under oil palm cultivation is Indonesia, at 3,769,000. ha, followed by Malaysia at 3,376,000. ha; however, the world’s leading producer of palm oil is still Malaysia, since the 1970’s. Both countries are predicted to produce 82.4% of the world’s palm oil production by the year 2005. However, the palm is susceptible to basal stem rot, a devastating disease which results in direct loss of field stands and to which no effective chemical control is yet available. Caused by Ganoderma boninense, infected palms appear symptomless, at the first sign of disease, at least 50% of the internal trunk tissue stem would have actually rotted. This study investigated the efficacy of Trichoderma harzianum (isolate FA 1132) as a biological control agent, using 6-month old oil palm seedlings as models and the experiment performed in a greenhouse at 29- 30 ℃. ambient conditions. The plants were artificially infected with G. boninense and a conidial suspension of 1×109-9×109 spores/mL was applied as a soil drench at 1L/plant every 2 weeks for 20 weeks. The parameters examined were efficacy of the biocontrol agent and the effect of Trichoderma- incorporated mulch in addition to the soil drench. Efficacy was assessed in terms disease severity index (DSI) where a higher percentage indicates a higher severity. Results showed that infection first sets in on untreated plants at week 12 and got worse progressively. The completely untreated plants were all infected and the DSI at 20 weeks after infection (wa.i.) was 92.5%. Plants given only a Trichoderma -infused food base supplement without conidial suspension gave a DSI of 70% whereas those given a conidial soil drench without supplemental food base gave a DSI of 85% at 20 w.a.i. Infected plants given a conidial treatment together with a food base supplement gave a DSI of 5%

关键词：油棕榈茎腐病生物防治病害木霉素

Sigmoid schwannoma: A rare case

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World Journal of Gastroenterology 2005年第32期11卷 5079-5081页

作者： Constantine I.Fotiadis ilias A.Kouerinis Ioannis Papandreou George C.Zografos George Agapitos Third Department of Propaudeutic SurgeryUniversity of Athens Sotiria HospitalAthens Greece First Department of Propaudeutic SurgeryUniversity of Athens Hippokration HospitalAthensGreece Third Department of Propaudeutic SurgeryUniversity of Athens Sotiria HospitalAthensGreece

Schwannomas are rare tumors derived from the cells of Schwann that form the neural sheath. When located in the gastrointestinal tract, they constitute together with leiomyoma, leiomyoblastoma, and leiomyosarcoma, the gastrointestinal stromal tumors (GIST). Peripheral nerve sheath tumors represent 2-6% GIST with most common location, the stomach and the small intestine. Schwannomas of the colon and rectum are extremely rare and radical excision with wide margins is mandatory, due to their tendency to recur locally and become malignant, if left untreated. In the present study, we report a rare case of a sigmoid schwannoma, which was successfully treated in our department and reviewed the literature.

关键词： Schwannoma Rectum GIST Tumor Prognosis Treatment

Molecular markers(PECAM-1,ICAM-3,HLA-DR)determine prognosis in primary non-Hodgkin's gastric lymphoma patients

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World Journal of Gastroenterology 2006年第12期12卷 1924-1932页

作者： Alexander Darom ilias P Gomatos Emmanuel Leandros Emmu Chatzigianni Dimitris Panousopoulos Manousos M Konstadoulakis George Androulakis Laboratory of Surgical Research First Department of Propaedeutic SurgeryAthens Medical SchoolHippokration Hospital of Athens114 Q.Sofia Ave11527 AthensGreece

AIM： To investigate the prognostic significance of PECAM-1, ICAM-3 and HLA-DR antigens in patients with primary non-Hodgkin＇s gastric lymphoma. METHODS： We immunohistochemically studied PECAM-1, ICAM-3 and HLA-DR antigen expression in 36 B-cell MALT-type primary gastric lymphoma patients. Ten non-malignant and ten healthy gastric tissue specimens were used as controls. Clinicopathological and survival data were correlated with the staining results. RESULTS： HLA-DR antigen expression was detected in 33 gastric lymphoma patients （91.7%） and 6 nonmalignant patients （54.5%）. PECAM-1 stained tumor cells of 10 patients （27.8%）, endothelial cells of 9 patients （25%） and inflammatory infiltrate of 4 patients （40%） with benign gastric disease. ICAM-3 expression was observed on the tumor cells of 17 patients （47.2%）, while 5 non-malignant patients （50%） were stained positive as well. None of the healthy controls was stained for any of the genes studied. In the multivariate analysis, HLA-DR antigen and PECAM-1 were proved to be statistically significant independent prognostic factors associated with a favourable and an unfavourable prognosis respectively （P= 0.009 and P= 0.003）. In the univariate analysis, PECAM-1（＋）/ICAM-3（-） and HLA-DR（-）/ICAM-3（-） patients exhibited a significantly decreased overall survival compared to those with the exactly opposite gene expression patterns （P=0.0041 and P= 0.0091, respectively）. Those patients who were HLA-DR（＋）/ICAM-3（＋）/PECAM-I（-）（n = 8） had a significantly higher survival rate compared to the rest of the group （n = 24）（P= 0.0289）. CONCLUSION： PECAM-1, ICAM-3 and HLA-DR are representative markers of tumor expansion potential and host immune surveillance respectively. Their combined use may help us to identify high-risk patients who could benefit from more aggressive therapeutic protocols.

关键词： PECAM-1 ICAM-3 HLA-DR Non-Hodgkin's gastric lymphoma Prognosis

Catalyzing Singlet Fission by Transition Metals:Second versus Third Row Effects

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Precision Chemistry 2023年第9期1卷 555-564页

作者： Yuxuan Hou ilias Papadopoulos Yifan Bo Anna-Sophie Wollny Michael J.Ferguson Lukas A.Mai Rik R.Tykwinski Dirk M.Guldi Department of Chemistry University of AlbertaEdmontonAlberta T6G 2G2Canada Department of Chemistry and Pharmacy&Interdisciplinary Center for Molecular Materials(ICMM) Friedrich-Alexander-University Erlangen-Nuremberg91058 ErlangenGermany Department of Applied Chemistry Graduate School of EngineeringCenter for Molecular Systems(CMS)Kyushu University744 Moto-okaNishi-kuFukuoka 819-0395Japan

The synthesis and characterization of platinum(II)and palladium(II)complexes bearing two(dimers Pt(L_(pc))_(2)Cl_(2)and Pd(L_(pc))_(2)Cl_(2)),one(monomers Pt(L_(pc))(L_(ref))Cl_(2)and Pd(L_(pc))(L_(ref))-Cl_(2)),or no(reference compounds Pt(L_(ref))_(2)Cl_(2)and Pd(L_(ref))_(2)Cl_(2))pentacene-based pyridyl ligands are *** properties of the dimers are probed by means of steady-state and time-resolved transient absorption measurements in compar-ison to the monomer and model *** results document that despite enhanced spin−orbit coupling from the presence of heavy atoms,intramolecular singlet fission(iSF)is not challenged by intersystem *** thus yields correlated triplet pairs and even uncorrelated triplet excited states upon ***,significant separation of the two pentacenyl groups facilitates decoupling of the two ***,the mechanism of iSF is altered depending on the respective metal center,that is,Pt(II)versus Pd(II).The dimer based on Pt(II),Pt(L_(pc))2Cl_(2),exhibits a direct pathway for the iSF and forms a correlated triplet pair with singlet−quintet spin-mixing within 10 ns in variable *** the other hand,the dimer based on Pd(II),Pd(L_(pc))_(2)Cl_(2),leads to charge transfer mixing during the population of the correlated triplet pair that is dependent on solvent ***,Pd(L_(pc))_(2)Cl_(2)gives rise to a stable equilibrium between singlet and quintet correlated triplet pairs with lifetimes of up to 170 *** differences in the size and polarizability,when contrasting platinum(II)with palladium(II),are the most likely rationale for the underlying trends.

关键词： metal complexes singlet fission pentacene dimers ultrafast spectroscopy electronic coupling

The Electricity Market Structure in Greece and the Paradox of Renewable Energy Sources

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Journal of Power and Energy Engineering 2019年第4期7卷 1-26页

作者： ilias G. Doulos Nikolas M. Katsoulakos Dimitris C. Kaliampakos Metsovion Interdisciplinary Research Center National Technical University of Athens Greece School of Mining and Metallurgical Engineering National Technical University of Athens Athens Greece

The European Union, in an effort to boost the use of Renewable Energy Sources (RES) in power generation, applies supportive tools consisting in financial motivation either as grants or as subsidies. According to welfare economics, a subsidy should reflect the external benefits;otherwise a distortion of competition takes place. The most widespread method to calculate externalities is the avoided cost approach, despite the fact that it encounters equally all the RES units leading to technological neutrality. In the present article, the avoided cost approach with the objective social justification of RES subsidies/feed in tariffs (FITs) in the case of Greece, for the year 2014, is applied. The results show a high gap between the current FITs and the suggested ones amounting to approximately 40%. This uncomfortable outcome indicates that, at least in the case of Greece, either the level of the current guaranteed tariffs is not socially justified, or the CO2 value derived from the European carbon market does not reflect the real social cost, or that the avoided cost method, alone, is not adequate to explain the level of subsidies. In light of the foregoing, the need for the development of a concrete and integrated methodology for calculating all RES externalities emerges.

关键词： Renewable Energy Feed in Tariff Avoided Cost Welfare Economics Pricing Externalities

Gut microbiome in alcohol use disorder:Implications for health outcomes and therapeutic strategies-a literature review

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World Journal of Methodology 2024年第1期14卷 33-44页

作者： ilias Koutromanos Evangelia Legaki Maria Gazouli Efthimios Vasilopoulos Anastasios Kouzoupis Elias Tzavellas First Department of Psychiatry "Aiginition"HospitalSchool of MedicineNational and Kapodistrian University of AthensSchool of MedicineNational and Kapodistrian University of AthensAthens 11528Greece Department of Basic Biological Science School of MedicineNational and Kapodistrian University of AthensAthens 11527Greece Department of Basic Medical Sciences Medical SchoolNational and Kapodistrian University of AthensAthens 11527Greece

Alcohol use disorder(AUD)represents a major public health issue which affects millions of people globally and consist a chronic relapsing condition associated with substantial morbidity and *** gut microbiome plays a crucial role in maintaining overall health and has emerged as a significant contributor to the pathophysiology of various psychiatric *** evidence suggests that the gut microbiome is intimately linked to the development and progression of AUD,with alcohol consumption directly impacting its composition and *** review article aims to explore the intricate relationship between the gut microbiome and AUD,focusing on the implications for mental health outcomes and potential therapeutic *** discuss the bidirectional communication between the gut microbiome and the brain,highlighting the role of microbiotaderived metabolites in neuroinflammation,neurotransmission,and mood ***,we examine the influence of AUD-related factors,such as alcohol-induced gut dysbiosis and increased intestinal permeability,on mental health ***,we explore emerging therapeutic avenues targeting the gut microbiome in the management of AUD,including prebiotics,probiotics,and fecal microbiota *** the complex interplay between the gut microbiome and AUD holds promise for developing novel interventions that could improve mental health outcomes in individuals with AUD.

关键词： Alcohol use disorder Gut microbiome Dysbiosis

Artificial night light and thyroid cancer

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World Journal of Methodology 2024年第1期14卷 87-93页

作者： Athanasios Tselebis Eftychia Koukkou Charalampos Milionis Lina Zabuliene Argyro Pachi Ioannis ilias Department of Psychiatry “Sotiria”General Chest Diseases HospitalAthens GR-11527Greece Department of Endocrinology Diabetes and MetabolismElena Venizelou General HospitalAthens GR-11521Greece Faculty of Medicine Vilnius UniversityVilnius LT-03101Lithuania

BACKGROUND The occurrence of thyroid cancer(TC)has increased in recent *** to outdoor artificial light at night(ALN)is associated with an increased risk of *** To investigated the impact of ALN,as a significant environmental pollutant,on TC incidence *** The assessment involved analyzing satellite ALN data in conjunction with TC incidence data[adjusted standardized rate(ASR)],while considering the quality of cancer registries(QCR),gross domestic product(GDP)per person,and health expenditure per person(HEP)for each *** Results indicated a correlation between higher ASR and ALN exposure percentages,particularly in countries with higher GDP or HEP quartiles(all P0.10).CONCLUSION The findings suggest a potential link between higher GDP and adverse health conditions,serving as possible risk factors for TC,rather than a direct association with *** include the use of cross-sectional data,temporal misalign ment,and reliance on ALN as a socioeconomic *** is proposed that light pollution might be connected to a lifestyle conducive to ***,the presence of higher GDP/HEP could enhance access to diagnostic resources,potentially facilitating TC diagnosis and inclusion in cancer registries.

关键词： Lighting Human Epidemiology Thyroid Cancer