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Journal of Environmental Sciences 2006年第1期18卷 193-200页

作者： Jae-Wook Lee Tae-Ouk Kwon Ramesh Thiruvenkatachari il-shik moon Department of Chemistry Engineer Seonam University Namwon 590-711 Korea Department of Chemistry Engineer Sunchon National University Suncheon 540-742 Korea

This study evaluates the adsorption ability ofbisphenol A（BPA） on titanium dioxide（TiO2） and its effect on the photocatalysis by advanced oxidation process using UV radiation and TiO2 photocatalyst. Degradation of BPA was also evaluated for the system without adsorption prior to photocatalytic reaction. The separation of TiO2 from BPA solution treated by pilot-scale photocatalytic reactor （capacity 0.16 m^3） was studied using submerged ultrafiltration （UF） membrane. It was found that although adsorption capacity of BPA was not high, adsorption played an important role in improving the efficiency ofphotocatalysis. On the other hand, during the separation of TiO2 particles from aqueous suspension, the permeate flux of the membrane was strongly affected by transmembrane pressure and TiO2 dose. The permeate turbidity was decreased below 1 NTU.

关键词： bisphenol A TiO2 adsorption membrane photocatalysis

Erythrocytes serve as a template to create nanozymes with uniform Fe single-atom sites for healing bacteria-infected wound

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Science China Life Sciences 2024年第9期67卷 2048-2050页

作者： Thinh Viet Dang moon il Kim Department of Bio Nano Technology Gachon University

Bacterial infection is recognized as one of the biggest global health threats, causing millions of people's death every year(Wang et al., 2020). Traditional antibiotics-based therapies have been widely utilized to control this issue(Kohanski et al., 2010); however, their excessive use leads to the emergence of antibioticresistant bacteria, endangering to human health(Levy and Marshall, 2004).

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Changes in structural plasticity of hippocampal neurons in an animal model of multiple sclerosis

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Zoological Research 2024年第2期45卷 398-414页

作者： Poornima D.E.Weerasinghe-Mudiyanselage Sohi Kang Joong-Sun Kim Sung-Ho Kim Hongbing Wang Taekyun Shin Changjong moon Department of Veterinary Anatomy and Animal Behavior College of Veterinary Medicine and BK21 FOUR ProgramChonnam National UniversityGwangju 61186Republic of Korea Department of Anatomy and Convergence Medical Science Institute of Health SciencesCollege of MedicineGyeongsang National UniversityJinju 52727Republic of Korea Department of Physiology and Neuroscience Program Michigan State UniversityEast LansingMI 48824USA Department of Veterinary Anatomy College of Veterinary Medicine and Veterinary Medical Research InstituteJeju National UniversityJeju 63243Republic of Korea

Structural plasticity is critical for the functional diversity of neurons in the *** autoimmune encephalomyelitis(EAE)is the most commonly used model for multiple sclerosis(MS),successfully mimicking its key pathological features(inflammation,demyelination,axonal loss,and gliosis)and clinical symptoms(motor and non-motordysfunctions).Recentstudieshave demonstrated the importance of synaptic plasticity in EAE *** the present study,we investigated the features of behavioral alteration and hippocampal structural plasticity in EAE-affected mice in the early phase(11 days post-immunization,DPI)and chronic phase(28DPI).EAE-affected mice exhibited hippocampus-related behavioral dysfunction in the open field test during both early and chronic *** complexity was largely affected in the cornu ammonis 1(CA1)and CA3 apical and dentate gyrus(DG)subregions of the hippocampus during the chronic phase,while this effect was only noted in the CA1 apical subregion in the early ***,dendritic spine density was reduced in the hippocampal CA1 and CA3 apical/basal and DG subregions in the early phase of EAE,but only reduced in the DG subregion during the chronic ***,mRNA levels of proinflammatory cytokines(il1β,Tnfα,and Ifnγ)and glial cell markers(Gfap and Cd68)were significantly increased,whereas the expression of activity-regulated cytoskeletonassociated protein(ARC)was reduced during the chronic ***,exposure to the aforementioned cytokines in primary cultures of hippocampal neurons reduced dendritic complexity and ARC *** cultures of hippocampal neurons also showed significantly reduced extracellular signal-regulated kinase(ERK)phosphorylation upon treatment with proinflammatory ***,these results suggest that autoimmune neuroinflammation alters structural plasticity in the hippocampus,possibly through the ERK-ARC pathway,indicating that this alteration may be associated with hi

关键词： Activity-regulated cytoskeleton-associated protein Anxiety-like behavior Experimental autoimmune encephalomyelitis Hippocampal dysfunction Neuroinflammation

Degradable and Tunable Keratin-fibrinogen Hydrogel as Controlled Release System for Skin Tissue Regeneration

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Journal of Bionic Engineering 2023年第3期20卷 1049-1059页

作者： Sung Jun Min Jae Seo Lee Haram Nah Ho-Jin moon Sang Jin Lee Hyeon Jeong Kang Yu-shik Hwang il Keun Kwon Dong Nyoung Heo Department of Dentistry Graduate SchoolKyung Hee University26 Kyungheedae-RoDongdaemun-GuSeoul02447Republic of Korea Biofriends Inc 26 Kyungheedae-RoDongdaemun-GuSeoul02447Republic of Korea Department of Dental Materials School of DentistryKyung Hee University26 Kyungheedae-RoDongdaemun-GuSeoul02447Republic of Korea Department of Maxillofacial Biomedical Engineering and Institute of Oral Biology School of DentistryKyung Hee UniversitySeoul02447Korea Kyung Hee University Medical Science Research Institute Kyung Hee University23 Kyungheedae-RoDongdaemun-GuSeoul02447Republic of Korea

Biodegradable hydrogels are promising biomaterials for use in controlled-release systems for skin tissue regeneration. Controlled delivery systems constitute an important aspect of tissue engineering because they can modulate various physiological responses, including early immune response, tissue remodeling, and cell proliferation and maturation in the wound-healing process. Hydrogels composed of various biomaterials have been developed to overcome the limitations of conventional drug- or protein-delivery systems, such as limited targeting ability, low stability, and the induction of drug resistance. Hydrogels based on keratin, a natural polymer extracted from human hair, can provide adequate cell support and control homeostasis. Consequently, they can be applied for skin tissue engineering. In this study, we prepared degradable, tunable, and biocompatible hydrogels for controllable protein delivery. We synthesized keratin-fibrinogen (KER-FBG) by the chemical coupling reaction and prepared hydrogels through polymerization with thrombin. The structures and morphologies of the KER-FBG hydrogels were confirmed. Furthermore, the mechanical properties, swelling ratio, degradation, release behavior, and biocompatibility were investigated. The KER-FBG hydrogels presented promising biological performance, indicating that the material is suitable as a controlled protein delivery carrier.

关键词： Keratin Fibrinogen Hydrogel Drug delivery Degradable

Augmenting freshwater availability in mountain headwater streams:Assessing the sustainability under baseline and future climate change scenarios

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International Soil and Water Conservation Research 2022年第2期10卷 293-307页

作者： Bisrat Ayalew Yifru il-moon Chung Min-Gyu Kim Sun Woo Chang Department of Land Water and Environment ResearchKorea Institute of Civil Engineering and Building TechnologyGoyang10223South Korea Department of Civil and Environmental Engineering University of Science and TechnologyDaejeon34113South Korea

Mountain headwater streams are important freshwater sources,but they are mostly intermittent and highly susceptible to climate *** paper examines the sustainability of augmented freshwater availability in mountain headwater streams for water supply under baseline and future climate change scenarios using an integrated modeling *** climate change data in the 2040s(2030e2059),under Representative Concentration Pathway 4.5 and 8.5 scenarios,were downscaled for the impact *** the region,climate change raises the average precipitation by 5e7%and the temperature by 13e15%in the *** model,integrating Soil and Water Assessment Tool(SWAT2012)and finite-difference Modular Groundwater Flow(MODFLOW)models in a single package,was used to assess the water *** show that extracting a minimum of 16.2 m^(3)/day from the sand storage and 30 m^(3)/day from the aquifer was possible without affecting the groundwater table and water *** average annual catchment recharge was 6%of the precipitation under the baseline *** change is projected to reduce the average water yield and groundwater recharge by 26%and 19%,***,the water supply-demand is significantly small compared to the exploitable rate of water in the *** study was based on limited data,and therefore the findings need to be interpreted with caution,though the model output was validated using satellite *** of a series of sand dams is suggested to maximize the benefit under the potential climate change and water supply-demand increase.

关键词： Headwater stream Sand dam Korea SWATeMODFLOW Water conservation Climate change

Optimally arranged TiO_(2)@MoS_(2) heterostructures with effectively induced built-in electric field for high-performance lithium-sulfur batteries

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能源化学:英文版 2023年第8期83卷 496-508,I0012页

作者： Jeongyoub Lee Changhoon Choi Jung Been Park Seungho Yu Jinho Ha Hyungsoo Lee Gyumin Jang Young Sun Park Juwon Yun Hayoung Im Subin moon Soobin Lee Jung-il Choi Dong-Wan Kim Jooho moon Department of Materials Science and Engineering Yonsei UniversitySeoul 03722Republic of Korea School of Civil Environmental and Architectural EngineeringKorea UniversitySeoul 02841Republic of Korea Energy Storage Research Center Korea Institute of Science and Technology(KIST)Seoul 02792Republic of Korea School of Mathematics and Computing(Computational Science and Engineering) Yonsei UniversitySeoul 03722Republic of Korea

To overcome the serious technological issues affecting lithium-sulfur(Li-S) batteries,such as sluggish sulfur redox kinetics and the detrimental shuttle effect,heterostructure engineering has been investigated as a strategy to effectively capture soluble lithium polysulfide intermediates and promote their conversion reaction by integrating highly polar metal oxides with catalytically active metals ***,to fully exploit the outstanding properties of heterostructure-based composites,their detailed structure and interfacial contacts should be designed ***,optimally arranged TiO_(2)and MoS_(2)-based heterostructures(TiO_(2)@MoS_(2)) are fabricated on carbon cloth as a multifunctional interlayer to efficiently trap polysulfide intermediates and accelerate their redox *** to the synergistic effects between TiO_(2)and MoS_(2)and the uniform heterointerface distribution that induces the ideally oriented built-in electric field,Li-S batteries with TiO_(2)@MoS_(2)interlayers exhibit high rate capability(601 mA h g^(-1)at 5 C),good cycling stability(capacity-fade rate of 0.067% per cycle over 500 cycles at2 C),and satisfactory areal capacity(5.2 mA h cm^(-2)) under an increased sulfur loading of 5.2 mg cm^(-2).Moreover,by comparing with a MoS_(2)@TiO_(2)interlayer composed of reversely arranged heterostructures,the effect of the built-in electric field’s direction on the electrocatalytic reactions of polysulfide intermediates is thoroughly investigated for the first *** superior electrocatalytic activities of the rationally arranged TiO_(2)@MoS_(2)interlayer demonstrate the importance of optimizing the built-in electric field of heterostructures for producing high-performance Li-S batteries.

关键词： Lithium-sulfur batteries Shuttle effect TiO_(2)-MoS_(2)heterostructure engineering Built-in electric field Multifunctional interlayers

Automatic Verification of Biochemical Network Using Model Checking Method

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Chinese Journal of Chemical Engineering 2008年第1期16卷 90-94页

作者： Jinkyung Kim Younghee Lee il moon Department of Chemical Engineering Yonsei University 134 Shinchon-dong Seodaemun-gu Seoul 120-749 Korea

这研究集中于用模型检查的在生物过程的所有可能的路径的为活动范围能力，转变逻辑和层次结构的方法的自动寻找并且验证。为在在生物过程的复杂、大的网络以内的其他的路径的自动搜索和确认能提供解决方案的可观的数量，它是困难的手工... 详细信息

这研究集中于用模型检查的在生物过程的所有可能的路径的为活动范围能力，转变逻辑和层次结构的方法的自动寻找并且验证。为在在生物过程的复杂、大的网络以内的其他的路径的自动搜索和确认能提供解决方案的可观的数量，它是困难的手工地处理。模型检查是为如果，验证的一个自动方法一个电路或一个条件，表示了为一个并发的转变系统，满足在时间的逻辑表示的一套性质，例如计算的树逻辑(CTL ) 。这篇文章表示模型检查在生物化学的网络确认是可行的，它为在生化法特殊行为的性质查询并且寻找在模拟上显示出某些优点。

关键词：模型校核生化网络自动辨识方法实验研究

Preface to the Special Issue:Climate Change and Variability of Tropical Cyclone Activity

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Advances in Atmospheric Sciences 2022年第2期39卷 203-204页

作者： Liguang WU Bin WANG Johnny CLCHAN Kyung-Ja HA il-Ju moon Jun MATSUMOTO Zhemin TAN Ke FAN Department of Atmospheric and Oceanic Sciences Fudan UniversityShanghai 200438China International Pacific Research Center School of Ocean and Earth Science and TechnologyUniversity of HawaiiHonoluluHI 96822USA School of Energy and Environment City University of Hong KongHong KongChina Research Center for Climate Sciences Pusan National UniversityBusan 46241South Korea Typhoon Research Center Jeju National UniversityJeju 63243South Korea Research Center for Climatology Department of GeographyTokyo Metropolitan UniversityTokyo 192-0392Japan School of Atmospheric Sciences Nanjing UniversityNanjing 210023China School of Atmospheric Sciences Sun Yat-Sen UniversityZhuhai 519082China

Tropical cyclones(TCs) are one of the most destructive natural phenomena on Earth in terms of human-life and economic losses. It is currently a matter of prodigious public and scientific interest how TC activity has changed and will change in a warming climate. This special issue focuses on a challenging subject raised in the Intergovernmental Panel on Climate Change(IPCC) report and numerous research papers.

关键词： warming Earth raised

Two climate factors in May that affect Korean rainfall in September

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Acta Oceanologica Sinica 2013年第1期32卷 32-47页

作者： CHOI Ki-Seon moon il-Ju National Typhoon Center Korea Meteorological Administration College of Ocean Science/Ocean and Environment Research Institute Jeju National University

This study revealed a high positive correlation between rainfall in Korea during September and the trade wind （TW）/Arctic Oscillation （AO） index in May that combines two climate factors, low-level TWs and the AO. This correlation was identified on the basis of the difference in the 850 hPa streamline analysis between the positive and negative phases selected using the combined TW/AO index. In May, the spatial pattern of the anomalous pressure systems is similar to that in the positive AO phase. These anomalous pressure sys- tems continue in June to August （JJA） and September, but the overall spatial distribution shifts a little to the south. Particularly in September, a huge anomalous anticyclone centered over the southeast seas of Japan strengthens in most of the western north Pacific region and supplies a large volume of warm and humid air to the region near Korea. This characteristic is confirmed by the facts that during the positive TW/AO phase, the subtropical western north Pacific high （SWNPH） is more developed to the north and that the continu- ous positioning of the upper troposphere jet over Korea from May to September strengthens the anomalous upward flow, bringing warm and humid air to all layers. These factors contribute to increasing September rainfall in Korea during the positive TW/AO phase. Because the SWNPH develops more to the north in the positive phase, tropical cyclones tend to make landfall in Korea frequently, which also plays a positive role in increasing September rainfall in *** above features are also reflected by the differences in average rainfall between the six years that had the highest May Nifio 3.4 indices （El Niflo phase） and the six years that had the lowest May Niflo 3.4 indices （La Nifia phase）.

关键词： anomalous pressure Arctic Oscillation Korea low-level trade wind rainfall tropical cyclone

Recent progress on the seasonal tropical cyclone predictions over the western North Pacific from 2014 to 2020

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Tropical Cyclone Research and Review 2022年第1期11卷 26-35页

作者： Eun-Jeong Cha Se Hwan Yang Yu Sun Hyun Chang-Hoi Ho il-Ju moon Meso-scale Meteorological Phenomenon Research Team National Institute of Meteorological SciencesKorean Meteorological AdministrationJejuRepublic of Korea National Typhoon Center Korean Meteorological AdministrationJejuRepublic of Korea School of Earth and Environmental Sciences Seoul National UniversitySeoulRepublic of Korea Typhoon Research Center Jeju National UniversityJejuRepublic of Korea

This study summarized the procedure for the seasonal predictions of tropical cyclones(TCs)over the western North Pacific(WNP),which is currently operating at the Korea Meteorological Administration(KMA),Republic of *** methodology was briefly described,and its prediction accuracy was *** predictions were produced by synthesizing spatiotemporal evolutions of various climate factors such as El Ni no–Southern Oscillation(ENSO),monsoon activity,and Madden–Julian Oscillation(MJO),using four models:a statistical,a dynamical,and two statistical–dynamical *** KMA forecaster predicted the number of TCs over the WNP based on the results of the four models and season to season climate *** seasonal prediction of TCs is announced through the press twice a year,for the summer on May and fall on *** present results showed low accuracy during the period 2014–*** advance forecast skill,a set of recommendations are suggested.

关键词： Tropical cyclones Seasonal prediction Western north pacific Statistical model Statistical-dynamical model Dynamical model Forecast error and verification