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Computers, Materials & Continua 2025年第1期82卷 1277-1293页

作者： Min-kyeong kim Yeong Geol Lee Won-Hee Park Su-hwan Yun tae-Soon Kwon Duckhee Lee Railroad Test&Certification Division Korea Railroad Research Institute(KRRI)Cheoldo BangmulgwanroUiwang-si16105Republic of Korea Railroad Safety Division Korea Railroad Research Institute(KRRI)Cheoldo BangmulgwanroUiwang-si16105Republic of Korea

Urban railways are vital means of public transportation in *** than 30%of metropolitan residents use the railways,and this proportion is expected to *** enhance safety,the government has mandated the installation of closed-circuit televisions in all carriages by ***,cameras still monitored *** address this limitation,we developed a dataset of risk factors and a smart detection system that enables an immediate response to any abnormal behavior and intensive monitoring *** created an innovative learning dataset that takes into account seven unique risk factors specific to Korean railway *** data collection was conducted across the Shinbundang Line of the Incheon Transportation Corporation,and the Ui-Shinseol *** observed several behavioral characteristics and assigned unique annotations to *** also considered carriage *** performance was evaluated by camera placement and *** the camera installation plan was *** dataset will find immediate applications in domestic railway *** artificial intelligence algorithms will be verified shortly.

关键词： AI railway vehicle risk factor smart detection AI training data

Minimum dose path planning for facility inspection based on the discrete Rao-combined ABC algorithm in radioactive environments with obstacles

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Nuclear Science and Techniques 2023年第4期34卷 26-40页

作者： Kwon Ryong Hong Su il O Ryon Hui kim tae Song kim Jang Su kim Faculty of Energy Science Kim Il Sung UniversityPyongyangDemocratic People’s Republic of Korea High-Tech Research&Development Centre Institute of Information TechnologyKim Il Sung UniversityPyongyangDemocratic People’s Republic of Korea

Workers who conduct regular facility inspections in radioactive environments will inevitably be affected by ***,it is important to optimize the inspection path to ensure that workers are exposed to the least amount of *** study proposes a discrete Rao-combined artificial bee colony(ABC)algorithm for planning inspection paths with minimum exposure doses in radioactive environments with *** this algorithm,retaining the framework of the traditional ABC algorithm,we applied the directional solution update rules of Rao algorithms at the employed bee stage and onlooker bee stage to increase the exploitation ability of the algorithm and implement discretion using the swap operator and swap *** increase the randomness of solution generation,the chaos algorithm was used at the initialization *** K-opt operation technique was introduced at the scout bee stage to increase the exploration ability of the *** path planning in an environment with complex structural obstacles,an obstacle detour technique using a recursive algorithm was *** evaluate the performance of the proposed algorithm,we performed experimental simulations in three hypothetical environments and compared the results with those of improved particle swarm optimization,chaos particle swarm optimization,improved ant colony optimization,and discrete Rao’s *** experimental results show the high performance of the proposed discrete Rao-combined ABC algorithm and its obstacle detour capability.

关键词： Minimum dose Path planning Nuclear facility inspection ABC algorithm Rao algorithms Swap sequence K-opt operation

Increase in neurokinin-1 receptor-mediated colonic motor response in a rat model of irritable bowel syndrome

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World Journal of Gastroenterology 2005年第2期11卷 237-241页

作者： Jun-Ho La tae-Wan kim tae-Sik Sung Hyn-Ju kim Jeom-Yong kim il-Suk Yang Department of Physiology College of Veterinary MedicineSeoul National UniversityRepublic of Korea Department of Physiology College of Veterinary MedicineKyungpuk National UniversityRepublic of Korea Institute of Bioscience and Biotechnology Daewoong Pharm Co.Ltd.Republic of Korea

AIM: Irritable bowel syndrome (IBS) is a functional bowel disorder. Its major symptom is bowel dysmotility, yet the mechanism of the symptom is poorly understood. Since the neurokinin-1 receptor (NK1R)-mediated signaling in the gut is important in the control of normal bowel motor function,we aimed to investigate whether the NK1R-mediated bowel motor function was altered in IBS, using a rat IBS model that was previously reported to show colonic dysmotility in response to restraint ***: IBS symptoms were produced in male SpragueDawley rats by inducing colitis with acetic acid. Rats were left to recover from colitis for 6 d, and used for experiments 7 d post-induction of colitis. Motor activities of distal colon were recorded in ***: The contractile sensitivity of isolated colon to a NK1R agonist [Sar9, Met(O2)11]-substance P (1-30 nmol/L)was higher in IBS rats than that in normal rats. After the enteric neurotransmission was blocked by tetrodotoxin (TTX, 1 μmol/L), the contractile sensitivity to the NK1R agonist was increased in normal colon but not in IBS rat colon. The NK1R agonist-induced contraction was not different between the two groups when the agonist was challenged to the TTX-treated colon or the isolated colonic myocytes. A nitric oxide synthase inhibitor Nω-nitro-L-arginine methyl ester (L-NAME, 100 μmol/L) augmented the NK1R agonist-induced contraction only in normal rat ***: These results suggest that the NK1R-meidated colonic motor response is increased in IBS rats, due to the decrease in the nitrergic inhibitory neural component.

关键词： Irritable bowel syndrome Neurokinin-1 receptor

Peripheral corticotropin releasing hormone mediates post-inflammatory visceral hypersensitivity in rats

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World Journal of Gastroenterology 2008年第5期14卷 731-736页

作者： Jun-Ho La tae-Sik Sung Hyun-Ju kim tae-Wan kim Tong Mook Kang il-Suk Yang Department of Physiology College of Veterinary Medicine SeoulNational University Seoul 151-742 Republic of Korea Department of Physiology College of VeterinaryMedicine Kyungpuk National University Daegu 702-701Republic of Korea Department of Physiology SungkyunkwanUniversity School of Medicine Suwon 440-746 Republic ofKorea

AIM:To investigate whether peripheral corticotropin releasing hormone (CRH), which is up-regulated in intestinal inflammation, mediates the post-inflammatory visceral hypersensitivity in a rat model of colitis. METHODS:We measured mucosal myeloperoxidase (MPO) activity as a marker of inflammation, plasma CRH level, and abdominal withdrawal reflex (AWR) to colorectal distension as a visceral nociceptive response at 2, 7 and 14 d after the induction of colitis with 4% acetic acid. RESULTS:Colonic inflammation, quantified by MPO activity, significantly increased on d 2 and subsided thereafter, which indicated a resolution of inflammation within 7 d. On the contrary, plasma CRH level and AWR score were increased on d 2, remained high on d 7, and returned to control level on d 14. Intraperitoneal injection of a CRH antagonist, astressin (30 μg/kg), significantly attenuated the post-inflammatory visceral hypersensitivity on d 7. Furthermore, intraperitoneal administration of CRH (3 and 10 μg/kg) mimicked the post-inflammatory visceral hypersensitivity in naive rats. CONCLUSION:These results suggest that increased peripheral CRH mediates the enhanced visceral nociception in rats recovered from experimental colitis.

关键词： Corticotropin releasing hormone Visceral hypersensitivity Colitis

Finite element and experimental analysis of Vickers indentation testing on Al_2O_3 with diamond-like carbon coating

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Journal of Central South University 2012年第5期19卷 1175-1181页

作者： ZHAI Jian-guang WANG Yi-qi kim tae-gyu SONG Jung-il Department of Mechanical Engineering Changwon National University Changwon 641-773 Korea Department of Nanosystem and Nanoprocess Engineering Pusan National University Pusan 609-735 Korea

Numerical simulation and experimental study of the Vickers indentation testing of the Al2O3 ceramic coated by diamond-like carbon(DLC) layer were *** numerical analysis was implemented by a two-dimensional finite element(FE) axis symmetry *** analysis results gave insight into the fracture mechanism of DLC films coated on brittle ceramic(Al2O3) *** maximum principal stress field was used to locate the most expected area for crack formation and propagation during the Vickers indentation *** results show that the median crack initiates in the interface under indenter,before ring crack occurs as the indenter presses ***,the plastic deformation appears when the indenter penetrates into the *** thicker DLC coating increases the Vickers hardness and fracture toughness.

关键词： Vickers indentation testing finite element diamond-like carbon Al2O3 fracture toughness

Polysplenia syndrome with preduodenal portal vein detected in adults

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World Journal of Gastroenterology 2008年第41期14卷 6418-6420页

作者： Hyung-il Seo tae Yong Jeon Mun Sup Sim Suk kim Department of Surgery Postgraduate School of Medicine and Medical Research Institute Pusan National University Department of Radiology Postgraduate School of Medicine Pusan National University

Polysplenia syndrome, defined as the presence of multiple spleens of almost equal volume, is a rare condition involving congenital anomalies in multiple organ systems. We report this anomaly in a 41-year-old female who underwent a left lateral sectionectomy due to recurrent cholangitis and impacted left lateral duct stones. Polysplenia syndrome with preduodenal vein was diagnosed preoperatively by computed to-mography (CT) and surgery was done safely. Although the polysplenia syndrome with preduodenal portal vein (PDPV) in adult is rarely encountered, surgeons need to understand the course of the portal vein and exercise caution in approaching the biliary tract.

关键词： Polysplenia Polysplenia syndrome Preduodenal portal vein Intrahepatic duct stones Congenital anomaly

Inferring community properties of benthic macroinvertebrates in streams using Shannon index and exergy

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Frontiers of Earth Science 2014年第1期8卷 44-57页

作者： Tuyen Van NGUYEN Woon-Seok CHO Hungsoo kim il Hyo JUNG YongKuk kim tae-Soo CHON Department of Mathematics Pusan National University Busan 609-735 Korea Department of Biological Sciences Pusan National University Busan 609-735 Korea DSPENALO National Robotics Research Center Pusan National University Busan 609-735 Korea Department of Mathematics Kyungpook National University Daegu 702-701 Korea

Definition of ecological integrity based on community analysis has long been a critical issue in risk assessment for sustainable ecosystem management. In this work, two indices （i.e., Shannon index and exergy） were selected for the analysis of community properties of benthic macroinvertebrate community in streams in Korea. For this purpose, the means and variances of both indices were analyzed. The results found an extra scope of structural and functional properties in communities in response to environmental variabilities and anthropogenic disturbances. The combination of these two parameters （four indices） was feasible in identification of disturbance agents （e.g., industrial pollution or organic pollution） and specifying states of communities. The four-aforemen- tioned parameters （means and variances of Shannon index and exergy） were further used as input data in a self- organizing map for the characterization of water quality. Our results suggested that Shannon index and exergy in combination could be utilized as a suitable reference system and would be an efficient tool for assessment of the health of aquatic ecosystems exposed to environmental disturbances.

关键词： benthic macroinvertebrates ecological integ-rity anthropogenic pollution self-organizing map

Cavity-Suppressing Electrode Integrated with Multi-Quantum Well Emitter:A Universal Approach Toward High-Performance Blue TADF Top Emission OLED

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Nano-Micro Letters 2022年第4期14卷 75-89页

作者： il Gyu Jang Vignesh Murugadoss tae Hoon Park Kyung Rock Son Ho Jin Lee WanQi Ren Min Ji Yu tae Geun kim School of Electrical Engineering Korea UniversityAnam-ro 145Seongbuk-guSeoul 02841Republic of Korea

A novel device structure for thermally activated delayed fluorescence(TADF)top emission organic light-emitting diodes(TEOLEDs)that improves the viewing angle characteristics and reduces the efficiency roll-off is ***,we describe the design and fabrication of a cavity-suppressing electrode(CSE),Ag(12 nm)/WO_(3)(65 nm)/Ag(12 nm)that can be used as a transparent *** the TADF-TEOLED fabricated using the CSE exhibits higher external quantum efficiency(EQE)and improved angular dependency than the device fabricated using the microcavity-based Ag electrode,it suffers from low color purity and severe efficiency *** drawbacks can be reduced by using an optimized multi-quantum well emissive layer(MQW EML).The CSE-based TADF-TEOLED with an MQW EML fabricated herein exhibits a high EQE(18.05%),high color purity(full width at half maximum~59 nm),reduced efficiency roll-off(~46%at 1000 cd m^(−2)),and low angular *** improvements can be attributed to the synergistic effect of the CSE and MQW *** optimized transparent CSE improves charge injection and light outcoupling with low angular dependence,and the MQW EML effectively confines charges and excitons,thereby improving the color purity and EQE *** proposed approach facilitates the optimization of multiple output characteristics of TEOLEDs for future display applications.

关键词： Cavity suppression Multi-quantum well Viewing angle Efficiency roll-off Top emission OLED

Pancreatic adenocarcinosarcoma of monoclonal origin:A case report

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World Journal of Gastroenterology 2014年第35期20卷 12682-12686页

作者： Hyun Seon kim Jin il kim Minyoung Jeong Jae Hyun Seo il Kyu kim Dae Young Cheung tae-Jung kim Chang Suk Kang Department of Internal Medicine The Catholic University of KoreaCollege of MedicineYeouido St.Mary’s Hospital Hospital Pathology Department The Catholic University of KoreaCollege of MedicineYeouido St.Mary’s Hospital

Adenocarcinosarcoma, a neoplasm containing both carcinomatous and sarcomatous components, is a rare form of a cancer and the pathophysiology is currently poorly understood. Moreover, definitive treatment guidelines for this disease have not yet been established. Pancreatic adenocarcinosarcoma is even more rare and the prognosis is fatal. Here, we report a case of a 77-year-old male with pancreatic adenocarcinosarcoma and metastasis to the liver. The patient presented at our hospital with uncontrolled glucose levels and diabetes mellitus. The patient’s laboratory findings were unremarkable with the exception of elevated carbohydrate antigen 19-9 levels. Biopsies of the tumors in the pancreas and the liver revealed two types of tumors: pancreatic adenocarcinoma and a poorly differentiated sarcoma. To determine if KRAS mutations were present, we performed a peptide nucleic acid (PNA) clamp PCR-based assay. DNA sequencing by PNA clamp PCR identified a point mutation in codon 12 of exon 2 within KRAS from both tumor types. Because the KRAS mutation is observed in both tumor components, our findings support a monoclonal tumor origin followed by subsequent divergent differentiation into the sarcomatous and carcinomatous tumor populations. After we considered the patient’s status and the late stage of tumor detection, gemcitabine chemotherapy was administered.

关键词： Pancreas Adenocarcinosarcoma Metastasis KRAS DNA sequencing

Ischemic colitis during interferon-ribavirin therapy for chronic hepatitis C:A case report

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World Journal of Gastroenterology 2012年第31期18卷 4233-4236页

作者： Su Jung Baik tae Hun kim Kwon Yoo il Hwan Moon Min-Sun Cho Department of Gastroenterology Health Promotion CenterYonsei University Gangnam Severance HospitalSeoul 158-050South Korea Department of Internal Medicine Ewha Medical Research InstituteEwha University Mokdong HospitalEwha Womans University School of MedicineSeoul 158-710South Korea Department of Pathology Ewha University Mokdong HospitalEwha Womans University School of MedicineSeoul 158-710South Korea

Ischemic colitis is a rare complication of interferon *** 9 cases in 6 reports have been described *** report describes a case of ischemic colitis during pegylated interferon and ribavirin treatment for chronic hepatitis C,and includes a review of the relevant literature.A 48-year-old woman was treated with pegylated interferon-2a and ribavirin for chronic hepatitis C,genotype *** 19 wk of treatment,the patient complained of severe afebrile abdominal pain with *** signs were stable and serum white blood cell count was within the normal *** computed tomography showed diffuse colonic wall thickening from the splenic flexure to the proximal sigmoid colon,which is the most vulnerable area for the development of ischemic *** revealed an acute mucosal hyperemic change,with edema and ulcerations extending from the proximal descending colon to the sigmoid *** mucosal biopsy revealed acute exudative *** chain reaction and culture for Mycobacterium tuberculosis were negative and the cultures for cytomegalovirus,Salmonella and Shigella species were *** discontinuation of interferon and ribavirin therapy,abdominal pain and hematochezia subsided and,following colonoscopy showed improvement of the mucosal *** colitis cases during interferon therapy in patients with chronic hepatitis C reported so far have all involved the descending *** colitis is a rarely encountered complication of interferon administration in patients with chronic hepatitis C and should be considered when a patient complains of abdominal pain and hematochezia.

关键词： Ischemia Hepatitis C Interferon