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Herbal compounds as promising therapeutic agents in precision medicine strategies for cancer:A systematic review

Journal of Integrative Medicine 2024年第2期22卷 137-162页

作者： Bizhar Ahmed Tayeb ikhwan yuda kusuma Alaa A.M.Osman Renáta Minorics Institute of Pharmacodynamics and Biopharmacy Faculty of PharmacyUniversity of Szeged6720 SzegedHungary Institution of Clinical Pharmacy Faculty of PharmacyUniversity of Szeged6725 SzegedHungary Department of Clinical Pharmacy and Pharmacy Practice Faculty of PharmacyUniversity of Gezira20 Wad MadaniSudan Pharmacy Study Program Facuity of HealthUniversitas Harapan BangsaPurwokerto 53182Indonesia

Background:The field of personalized medicine has gained increasing attention in cancer care,with the aim of tailoring treatment strategies to individual patients for improved *** medicine,with its long-standing historical use and extensive bioactive compounds,offers a rich source of potential treatments for various diseases,including ***:To provide an overview of the current knowledge and evidence associated with incorporating herbal compounds into precision medicine strategies for cancer ***,to explore the general characteristics of the studies included in the analysis,focusing on their key features and *** strategy:A comprehensive literature search was conducted from multiple online databases,including Pub Med,Scopus,Web of Science,and *** search strategy was designed to identify studies related to personalized cancer medicine and herbal *** criteria:Publications pertaining to cancer research conducted through in vitro,in vivo,and clinical studies,employing natural products were included in this *** extraction and analysis:Two review authors independently applied inclusion and inclusion criteria,data extraction,and assessments of methodological *** quality assessment and biases of the studies were evaluated based on modified Jadad scales.A detailed quantitative summary of the included studies is presented,providing a comprehensive description of their key features and ***:A total of 121 studies were included in this review for *** of them were considered as comprehensive experimental investigations both in vitro and in *** majority(n=85)of the studies included in this review were conducted in vitro,with 44 of them specifically investigating the effects of herbal medicine on animal ***,7 articles with a combined sample size of 31,271 patients,examined the impact of herbal medicine in clinical ***:Personal

关键词： Cancer Herbal medicine Personalized medication Active phytochemicals Natural compound

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Experiment and simulation to determine the optimum orientation of building-integrated photovoltaic on tropical building façades considering annual daylight performance and energy yield

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Energy and Built Environment 2024年第3期5卷 414-425页

作者： Rizki A.Mangkuto Dhian Nur Aziz T.Tresna ikhwan M.Hermawan Justin Pradipta Nurul Jamala Beta Paramita Atthaillah Building Physics Research Group Faculty of Industrial TechnologyInstitut Teknologi BandungLabtek VIJl.Ganesha 10Bandung 40132Indonesia Engineering Physics Program Faculty of Industrial TechnologyInstitut Teknologi BandungLabtek VIJl.Ganesha 10Bandung 40132Indonesia Engineering Physics Research Group Faculty of Industrial TechnologyInstitut Teknologi BandungLabtek VIJl.Ganesha 10Bandung 40132Indonesia Department of Architecture Faculty of EngineeringHasanuddin UniversityJl.Poros Malino Km.6Gowa 92171Indonesia Architecture Study Program Faculty of Technology and Vocational EducationUniversitas Pendidikan IndonesiaJl.Dr.Setiabudhi 229Bandung 40152Indonesia Architecture Program Faculty of EngineeringUniversitas MalikussalehJl.Cot Teungku NieAceh Utara 24355Indonesia

Building-Integrated Photovoltaic(BIPV)on vertical façades is a potential PV application in today’s *** performance of BIPV on façades is significantly influenced by the façade *** tropical cities,the optimum façade orientation,in terms of maximum energy yield and daylight performance,cannot be simply determined,due to relatively symmetrical sun path throughout the *** study therefore aims to determine the optimum orientation for BIPV on tropical building faç*** achieve the objective,experiment,modelling,and computational simulation are conducted to evaluate the BIPV energy yield and to predict the indoor daylight performance in a scale-model building with a 105Wp monocrystalline silicon PV,facing each cardinal orienta-tion in Bandung,*** South orientation yields practically zero ASE_(1000,250),providing the best annual daylight performance,and yielding the most desirable value in four out of five daylight *** greatest annual energy yield is at the North orientation,providing 179-186 kWh(95%prediction interval)per year,but with larger uncertainty compared to that at the South,due to direct sunlight *** on three different objective functions,the South orientation is considered optimum for placing the BIPV panel on the prototype façade in the location.

关键词： Building-integrated photovoltaic Orientation Daylight metric Energy yield Tropical building façade

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Dazed and Confused:The Impact of Multinational Firms on Local Labor Markets

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Macro Management & Public Policies 2022年第4期4卷 1-6页

作者： M.ikhwan Maulana Haeruddin Muhammad Akhsan Tenrisau Rudi Salam Muhammad Alfi Rifadli Mansur Universitas Negeri Makassar MakassarIndonesia Universitas Muslim Indonesia MakassarIndonesia Monash Business School MelbourneAustralia

In this high-speed globalization era,the opportunities for multinational companies(MNCs)have become *** such situation,these companies can obtain maximum profit only if they know how to use workforce *** paper aims at analyzing how these MNCs can use international workforce without violating ethics,universal labor rights,and human resource *** this purpose,two most favored countries i.e.,China and Indonesia have been taken and compared throughout the *** first part of this paper deals with the introduction of the profile of above mentioned two countries and opportunities to the *** second part deals with the roles of institutions in dealing with labor *** third part indicates divergent paths and the convergence of the globalization with its impact over host *** final part concludes the entire discussion in a few *** entire paper has been developed keeping the scholarly work,journal articles and critical analysis factor under consideration.

关键词： Multinational companies Labor Human resource management Industrial relation

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Successful Treatment of Adult Pleomorphic Rhabdomyosarcoma in the Posterior Left Femur: A Case Report

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International Journal of Clinical Medicine 2018年第4期9卷 315-326页

作者： Barlian Sutedja Abdul Muthalib ikhwan Rinaldi Terawan Agus Putranto Tjondro Setiawan Diah Rini Handjari Jubilate Edward I. Tambun Reza Adiwidjaja Department of Surgery GadingPluit Hospital Jakarta Indonesia Department of Oncology GadingPluit Hospital Jakarta Indonesia Department of Interventional Radiology GadingPluit Hospital Jakarta Indonesia Department of Radiology GadingPluit Hospital Jakarta Indonesia Department of Pathology GadingPluit Hospital Jakarta Indonesia General Practitioner of GadingPluit Hospital Jakarta Indonesia

Introduction: Rhabdomyosarcoma (RMS) is the most common childhood soft tissue sarcoma, but it represents only a small portion of soft tissue sarcoma in adult population. There is a treatment protocol based on Intergroup Rhabdomyosarcoma Study (IRS) that provides satisfactory results in treating RMS in children, but there is only limited evidence regarding the outcome and prognosis in extrapolating the IRS protocol to treat RMS in adults. We report a case of adult pleomorphic RMS treated with multidisciplinary approach and the results we have obtained. Case presentation: A 48-year-old woman was admitted in February 2011 due to a painful mass on her left thigh. Diagnosis of pleomorphic rhabdomyosarcoma was made by histopathology and immunohistochemistry. After multimodal treatment that includes Trans-Arterial Chemotherapy Infusion, Cryosurgery, and wide excision surgery, our patient remains disease-free as of the latest annual follow up examination on June 2017. Conclusions: The pleomorphic type of Rhabdomyosarcoma is very rare in adults and is often associated with a poor prognosis. In our case, a multidisciplinary approach with multimodal treatment provides excellent result, even after a routine follow up spanning through six years.

关键词： Rhabdomyosarcoma Pleomorphic Adult Multidisciplinary Approach Multimodality Treatment TACI Cryosurgery Surgery

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