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Geochemical Prospection of the Chapala Ciénega at Michoacán State

International Journal of Geosciences 2014年第9期5卷 1007-1011页

作者： José Martínez Reyes Ivan Vera Romero Meliton Estrada Jaramillo Agustina Ortiz Soriano ignacio moreno nava Francisco Gabriel Montes Ayala Francisco García ávalos Ernesto Mendez Ruiz 1University of the Ciénega of Michoacán State Sahuayo México 2Michoacan Society of History Archaeology and Geography A.C. La Palma de Jesús México Michoacan Society of History Archaeology and Geography A.C. La Palma de Jesús México University of the Ciénega of Michoacán State Sahuayo México

The geochemical prospection as a branch of Applied Geochemistry or “Geochemistry of the Landscape” studies the spatial and temporal location of geochemical anomalies in order to locate geological resources of economic value. The Ciénega de Chapala zone in Michoacán is located east of the Citala rift hosting a geological system that leads to regional hydrothermal activity, mainly the Pajacuaran and Ixtlan failures. The regional geothermics include a superficial hydrothermalism consisting of springs and wells of hot water with temperatures between 48°C and 94°C in Ixtlan de los Hervores and mud volcanoes in the water with temperatures between 48°C and 94°C in Ixtlan de los Hervores and mud volcanoes in the Los Negritos. The waters and gases of these hydrothermal manifestations have physicochemical characteristics that indicate the presence of geothermal fluids. To search for possible presence of minerals of economic value, a study of elemental chemical analysis was performed by scanning electron microscopy in samples of rock of the sierra de Pajacuaran, the result of the analysis is clearly abnormal values which may be indicative a geochemical anomaly as well as the possible presence of minerals of economic value in the region. Given the above, the area of the Ciénega de Chapala in Michoacán is a zone where work can be continued both geothermal and mineralogical exploration by conventional techniques or even totally innovative technologies.

关键词： Geochemical Prospection Ciénega Michoacán

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Effect of human disturbance on the structure and regeneration of forests in the Nevado de Toluca National Park, Mexico

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Journal of Forestry Research 2012年第1期23卷 39-44页

作者： Angel Rolando Endara Agramont Sergio Franco Maass Gabino nava Bernal Juan ignacio Valdez Hernández Todd S.Fredericksen Instituto de Ciencias Agropecuarias y Rurales(ICAR) Universidad Autónoma del Estado de MéxicoInstituto Literario N°100Col.Centro.PO.Box 50000.TolucaMéxico Colegio de Posgraduados Carretera México-TexcocoKm.36.5Montecillo.PO.Box 56230TexcocoMéxico School of Natural Sciences and Mathematics Ferrum CollegeP.O.Box 1000Ferrum VA 24088USA

Sample plots were established in the principal forest types in the the Nevado de Toluca National Park, Mexico including those domi- nated by Pinus hartwegii, Abies religiosa, Quercus laurina and Alnus jorullensis. The vertical structure was defined by three strata in the coniferous forests and two strata in the broadleaved forests. Timber harvesting in Abies religiosa and Quercus laurina forests and fires generated by humans in Pinus hartwegii forests impeded the recruitment of saplings. Mature trees were also heavily impacted by logging in Pinus hartwegii forests. On the contrary, Alnusjorullensis forests were increas- ing due to the disturbance of Pinus and Quercus forests, as well aban- doned crop lands within the park. A combination of logging, uncon- trolled fire, and grazing appears to be compromising the recruitment of important tree species in this national park. These factors, together with human settlements, have also increased the proportion of early succes- sional species. Changes in forest structure from human disturbance indicate a need to control these activities if conservation goals are not to be compromised.

关键词： forest structure human disturbance mountain forests

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Alpha2-adrenergic receptor activation reinstates motor deficits in rats recovering from cortical injury

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Neural Regeneration Research 2023年第4期18卷 875-880页

作者： Gabriela García-Díaz Laura ERamos-Languren Carmen Parra-Cid Joel Lomelí Sergio Montes Camilo Ríos Antonio Bueno-nava ignacio Valencia-Hernández Rigoberto González-Piña Department of Pharmacology Section of Postgraduate Studies and ResearchHigh Medical SchoolInstituto Politécnico NacionalSalvador Díaz MirónAlcaldía Miguel HidalgoMexico CityMexico Department of Neurobiology of Aging and Brain Damage Coordination of Psychobiology and NeurosciencesFaculty of PsychologyNational Autonomous University of MexicoAv.Universidad 3040Col.Copilco UniversidadAlcaldía CoyoacánMexico CityMexico Direction of Research National Institute of Rehabilitation LGIICalz.Mexico-Xochimilco 289Col.Arenal de GuadalupeAlcaldía TlalpanMexico CityMexico Department of Pharmacology Multidisciplinary Academic Unit Reynosa-Aztlan ReynosaAutonomous University of Tamaulipascalle 16 y lago de ChapalaCol.AztlánTamaulipasMexico Department of Neurochemistry National Institute of Neurology and Neurosurgery MVSAv.Insurgentes Sur 3877Col.La FamaAlcaldia TlalpanMexico CityMexico Department of Special Education University of the AmericasPuebla 223Col.RomaAlcaldía CuauhtémocMexico CityMexico

Norepinephrine plays an important role in motor functional recovery after a brain injury caused by ferrous *** of norepinephrine release by clonidine is correlated with motor deficits after motor cortex *** aim of this study was to analyze the role ofα-adrenergic receptors in the restoration of motor deficits in recovering rats after brain *** rats were randomly assigned to the sham and injury groups and then treated with the following pharmacological agents at 3 hours before and 8 hours,3 days,and 20 days after ferrous chloride-induced cortical injury:saline,clonidine,efaroxan(a selective antagonist ofα-adrenergic receptors)and clonidine+*** sensorimotor score,the immunohistochemical staining forα-adrenergic receptors,and norepinephrine levels were *** hours post-injury,the sensorimotor score and norepinephrine levels in the locus coeruleus of the injured rats decreased,and these effects were maintained 3 days ***,20 days later,clonidine administration diminished norepinephrine levels in the pons compared with the sham *** effect was accompanied by sensorimotor *** effects were blocked by *** conclusion,an increase inα-adrenergic receptor levels was observed after *** restores motor deficits in rats recovering from cortical injury,an effect that was prevented by *** underlying mechanisms involve the stimulation of hypersensitiveα-adrenergic receptors and inhibition of norepinephrine activity in the locus *** results of this study suggest thatαreceptor agonists might restore deficits or impede rehabilitation in patients with brain injury,and therefore pharmacological therapies need to be prescribed cautiously to these patients.

关键词： alpha2-adrenoceptors ambulatory behavior clonidine cortical injury efaroxan functional recovery immunohistochemistry motor deficit norepinephrine sensorimotor score

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Congenitally Corrected Transposition of the Great Arteries: Conduction Anomalies: A Case Report

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World Journal of Cardiovascular Diseases 2021年第9期11卷 439-444页

作者： Jose Antonio Luna-Alvarez-Amezquita Javier Ivan Armenta-moreno Joaquin Berarducci Jorge Luis Bermudez-Gonzalez Jose Luis Siller-nava Edson Alberto Escandón-Villalobos Nilda Espinola-Zavaleta Roberto Cano-Zarate Juan ignacio Straface Department of Nuclear Cardiology National Institute of Cardiology Ignacio Chavez Mexico City Mexico Department of Echocardiography ABC Medical Center I.A.P. Mexico City Mexico Department of Magnetic Resonance National Institute of Cardiology Ignacio Chavez Mexico City Mexico

Introduction: Congenitally corrected transposition of the great arteries (CCTGA) is a rare heart disease that encompasses an atrioventricular and ventriculoarterial discordance and accounts for less than 1 percent of congenital heart diseases. Objective: To present an atypical case of a man with complex congenital heart disease and conduction anomalies. Case Presentation: This is a case of a 34-year-old patient who came to the hospital with 1 week of dyspnea on exertion and episodes of lipothymia. The patient was referred to our hospital after an electrocardiogram from his primary care with evidence of blocked atrial fibrillation. During the initial evaluation blocked atrial fibrillation was confirmed with a rescue ventricular rate of 38 bpm. A magnetic resonance confirmed the presence of the atrioventricular and ventriculoarterial discordance, the aorta had a left anterior position, perimembranous ventricular septal defect with a right to left shunt, biventricular systolic dysfunction, moderate tricuspid, and mitral regurgitation, interventricular septal intramyocardial and biatrial fibrosis, left atrial dilation, and dilation of the pulmonary artery. After pacemaker placement, the patient has an improvement in his clinical symptoms and quality of life. Conclusions: Cardiac arrhythmias are CCTGA’s leading cause of death, mostly ventricular tachycardia, and atrial fibrillation. Right bundle branch block is a previously unreported and potentially very rare presentati

关键词： Congenital Heart Disease Congenitally Corrected Transposition of the Great Arteries Cardiac Magnetic Resonance Echocardiography Arrhythmia

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Interferon Regulatory Factor 5 and Renin-Angiotensin-Aldosterone System Polymorphisms in Coronary Artery Disease: An Overview of Experimental and Clinical Studies

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World Journal of Cardiovascular Diseases 2021年第7期11卷 332-341页

作者： Jorge Luis Bermudez-Gonzalez Rodrigo Dagio-Cuellar Cristina Villarreal-Guerrero Ana Gilabert-Garcia Luis Angel Ferral-Barbabosa Joaquin Berarducci Jose Luis Siller-nava Jose Antonio Luna-Alvarez-Amezquita Javier Iván Armenta-moreno Nilda Espínola-Zavaleta Erick Alexanderson-Rosas Juan ignacio Straface National Institute of Cardiology ignacio Chavez Mexico City Mexico Medicine Faculty of National Autonomous University of Mexico Mexico City Mexico

Heart diseases are the main cause of mortality in Mexico, being coronary heart disease the most frequent in the country. Its high prevalence makes important the study of the pathophysiology and the search for prognostic factors. Different genes and polymorphisms promote atherogenesis and coronary artery disease, they affect inflammatory and vascular pathological processes. Interferon regulatory factor 5 (IRF5) is associated with coronary heart disease, it promotes chronic inflammation and cytokines release;it could trigger immune reactions and its activating receptors express in the vascular endothelium. Besides, polymorphisms in the renin-angiotensin-aldosterone system (RAAS) are implied with coronary disease, they are found in angiotensinogen (AGT), angiotensin II type 1 receptor (AT1R), angiotensin II type 2 receptor (AT2R), and angiotensin-converting enzyme (ACE) genes. These genetic polymorphisms are associated with a prothrombotic state, endothelial dysfunction, and immune activation. Multiple experimental studies showed that chronic activation of RAAS and chronic expression of IRF5 generates an environment prone to the development of atherosclerosis, and autoimmune and cardiovascular diseases. Studying these specific genes and their relationship with coronary heart disease will allow a better understanding of the pathological process and possibly the quest for new treatments.

关键词： Interferon Regulatory Factor 5 (IRF5) Angiotensin-Converting Enzyme (ACE) Angiotensinogen (AGT) Angiotensin II Type 1 Receptor (AT1R) Angiotensin II Type 2 Receptor (AT2R) Polymorphisms

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Diagnosis of breast cancer by analysis of sialic acid concentrations in human saliva by surface-enhanced Raman spectroscopy of silver nanoparticles

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Nano Research 2017年第11期10卷 3662-3670页

作者： Aida Hernandez-Arteaga Jose de Jeses Zermeno nava Eleazar Samuel Kolosovas-Machuca J. Jesus Velazquez-Salazar Ekaterina Vinogradova Miguel Jose-Yacaman Hugo Ricardo navarro-Contreras Coordinacion para la Innovacion y Aplicacion de la Ciencia y la Tecnologia(CIACYT) Universidad Autonoma de San Luis Potosi(A)lvaro Obregon 64 San Luis Potosi S.L.P.78000 Mexico Division de Gineco-Obstetricia Hospital Central Dr.Ignacio Morones Prieto Ave.Venustiano Carranza 2395 Zona Universitaria San Luis Potosi S.L.P.78290 Mexico Department of Physics and Astronomy University of Texas at San Antonio San Antonio TX 78249 USA

Breast cancer is the most common type of malignant tumor among women and their second leading cause of cancer-related *** most common method for screening and diagnosis is ***,two main problems have been ***,the dose of radiation received during the test prevents the method from the use on women who are 〈 40 years ***,there can be mammogram failure owing to the lack of tumor contrast with the fibrous ***,there is a need for screening methods that will help to identify high-risk *** developed a biological marker test that can help to identify *** levels of sialic acid （SA） in saliva are known to correlated with breast *** this study,we evaluated the feasibility of Raman spectroscopy as a method for quantification of SA in saliva,using citrate-reduced silver nanoparticles （cit-Ag-NPs） as a surface-enhanced Raman spectroscopy （SERS） *** of SA was accomplished by measuring its intensity in saliva and comparing it with a calibration curve of SA *** mean SA concentration in saliva was found to be significantly higher among 100 breast cancer patients （18.3 ＆#177; 9.4 mg＆#183;dL-1;mean ＆#177; SD） than among 106 healthy controls （3.5 ＆#177; 1.0 mg＆#183;dL-1）.The SERS test showed sensitivity of 94% and specificity 98% for detection of patients with breast cancer,assuming that SA concentration 〉 7 mg＆#183;dL-1 is a cutoff for positive test *** findings prove the usefulness of this SERS technique as a simple,convenient,and highly sensitive method of quantitative analysis of SA in *** simplicity of this nanotechnological test may help to substantially reduce the mortality among patients with breast cancer by providing women with a simple,noninvasive screening test that can be applied regardless of age or density of breast tissue.

关键词： breast cancer surface-enhanced Raman spectroscopy (SERS) Raman nanoparticles sialic acid

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Long Term Follow-Up of Cardiotoxicity in Breast Cancer Treatment: A Case Report

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World Journal of Cardiovascular Diseases 2023年第3期13卷 130-137页

作者： Jose Luis Siller-nava Adrian Espejel-Guzman Javier Serrano-Roman Aldo Cabello-Ganem Alexis D. Aparicio Ortiz Nilda Espinola-Zavaleta Department of Nuclear Cardiology National Institute of Cardiology Ignacio Chavez Mexico City Mexico Mexican Social Security Institute IMSS Mexico City Mexico Department of Echocardiography ABC Medical Center I.A.P. Mexico City Mexico

Background: Cardiac toxicity is currently defined as a symptomatic decrease in Left Ventricular Ejection Fraction (LVEF) of more than 5% or an asymptomatic decrease of at least 10% to a value of under 50% in repeated evaluations on conventional transthoracic echocardiogram (TTE), as well as a Global Longitudinal Strain (GLS) value Aims: To highlight using GLS rather than modified Simpson 2D-LVEF for the evaluation of long-term cardiotoxicity. Case Presentation: The case concerns a 73-year-old female patient with a history of breast cancer chemotherapy and anthracyclines-based therapy who presented symptoms of late cardiac toxicity related to the chemotherapeutic treatment. In the following years, the patient remained asymptomatic with a 2D-LVEF of 48%, dilation of the left atrium was found, and the reservoir phase strain was severely decreased. Conclusion: The preferred method for evaluating cardiovascular complications associated with chemotherapy is the TTE, which is performed prior to the start of treatment, during therapy, and in the follow-up. Myocardial deformation as a predictor of cardiotoxicity allows the identification of subclinical heart failure.

关键词： Cardiotoxicity Breast Cancer Global Longitudinal Strain Left Ventricular Ejection Fraction Heart Failure

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神经电影学：电影中的神经科学

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当代电影 2018年第2期 30-36页

作者：乌里·哈森奥哈德·兰德斯曼芭芭拉·科耐普米尔伊格纳西奥·瓦莱恩斯纳瓦·鲁宾大卫·海格张婉宜王宜文美国普林斯顿大学纽约大学电影学纽约大学神经科学和心理学中心慕尼黑大学实验心理学系纽约大学神经科学纽约大学神经科学和心理学北京师范大学艺术与传媒学院

本文旨在研究一种用于评估电影对观影者脑活动影响的新方法。当观影者在自由观影时,利用功能性核磁共振成像(f MRI)测量观影者的脑活动数据,并结合被试者相关性分析(ISC)来评估在观看影片时观影者之间大脑在时空反应上的相似性。研究结... 详细信息

本文旨在研究一种用于评估电影对观影者脑活动影响的新方法。当观影者在自由观影时,利用功能性核磁共振成像(f MRI)测量观影者的脑活动数据,并结合被试者相关性分析(ISC)来评估在观看影片时观影者之间大脑在时空反应上的相似性。研究结果表明,某些影片对观影者脑活动及眼运动显示出显著的控制。但是,电影剧情、剪辑手段及导演风格的不同对观影者脑活动和眼运动产生的影响也不尽相同,所以这一结论无法推广至所有电影。如果能将不同类型的影片对观影者大脑的影响进行神经科学上的定量评估,那么ISC就可以对电影学研究有所帮助,成为电影产业更好地评估电影作品的有效方法。同时,这一方法将两个毫无关联的学科——认知神经科学和电影学结合在一起,开启了一个新的跨学科研究领域——神经电影学。

关键词：功能性核磁共振成像(fMRI) 被试者相关性认知电影理论社交神经科学认知控制

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