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Risk factors from HBV infection among blood donors:A systematic review

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Asian Pacific Journal of Tropical Biomedicine 2016年第4期6卷 344-349页

作者： Giuseppe la torre Rosella Saulle department of Public Health and Infectious Diseases "Sapienza" University of Rome

Objective:To perform a systematic review of the scientific literature to identify risk factors associated with hepatitis B viruses(HBV) infection among blood ***:The literature search was carried out on Pub Med and Scopus databases using the keywords "risk factors" "HBV infection" and "blood donors".No date or language restrictions were applied to the *** literature review was completed in *** selection process and the reporting of the review followed the Preferred Reporting Items for Systematic Reviews and Meta-Analyses *** Newcastle Ottawa scale was using to evaluate the quality of each single primary ***:Out of 172 records resulted in the search,5 papers were included in the final analysis because they are within acceptance *** of the selected studies were cross-sectional and three of them were case-control *** association resulted with some demographic and behavioral risk factors,such as marital status,dental treatment/procedure history,no stable relationship or multiple partners and family history of HBV ***:The systematic review performed encourages to conduct further research among blood donors in order to fully understand risk factors among donors in more extensive thus to provide valuable information about surveillance.

关键词： Risk factors HBV Infection Blood donors Systematic review

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中国早期人类分布的环境制约因素探讨

第四纪研究 2021年第5期41卷 1342-1356页

作者：丁馨杜雨薇徐欣裴树文 de la torre ignacio 高星英国伦敦大学学院考古研究所英国伦敦WC1H 0PY 中国科学院脊椎动物演化与人类起源重点实验室中国科学院古脊椎动物与古人类研究所机构北京100044 中国科学院机构生物演化与环境卓越创新中心北京100044 西班牙国家研究委员会历史研究所西班牙马德里28037 中国科学院大学机构北京100049

在环境因素起制约作用的背景下,随着中国古人类演化与生存能力的进步,其数量和空间分布在不同时间段呈现出不同的特征。为了更好地了解中国早期人类的时空分布特征,本研究以中国境内已发表的2110处旧石器遗址的坐标和年代信息为基础,采... 详细信息

在环境因素起制约作用的背景下,随着中国古人类演化与生存能力的进步,其数量和空间分布在不同时间段呈现出不同的特征。为了更好地了解中国早期人类的时空分布特征,本研究以中国境内已发表的2110处旧石器遗址的坐标和年代信息为基础,采用统计学和空间分析的方法,对遗址的时间分布进行以蒙特卡洛模拟为基础的时间不定性模拟,对遗址的空间分布进行核密度估计和聚类分析;同时,利用环境空间数据集中的海拔、水源、气温和降水信息,对不同时期内各个遗址所在地的环境条件进行统计分析。研究结果表明,在旧石器时代,随着时间的发展,中国境内的遗址数量不断增多,分布范围也逐渐从中部、南部和东部地区向条件较恶劣的北部和西部扩张。其中,600 ka和57 ka为这一变化的两个关键时间点,600 ka之前遗址数量较少,分布也较为局限;在600 ka至57 ka之间,遗址数量缓慢增加,分布范围也在季风区内逐渐扩大;57 ka之后,遗址数量迅速增长,分布遍布中国境内的大部分地区。本文所梳理的中国境内旧石器遗址整体时空分布特征,为进一步解读中国早期人类的环境适应能力,特别是古人类的体质演化和技术进步的环境驱动机制提供参考。

关键词：古人类分布环境因素空间分析统计分析中国

The roles of anurans in antagonistic networks are explained by life-habit and body-size

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Integrative Zoology 2022年第4期17卷 530-542页

作者： Amanda Caroline DUDCZAK Gabriel Massaccesi de la torre Lorena EUCLYdeS Karla Magalhães CAMPIÃO department of Zoology Federal University of ParanáCuritibaBrazil Postgraduate Program in Zoology Federal University of ParanáCuritibaBrazil Postgraduate Program in Ecology and Conservation Federal University of ParanáCuritibaBrazil

Interactions among living beings are the structuring basis of ecosystems,and studies of networks allow us to identify the patterns and consistency of such *** networks reflect the energy flow of communities,and identifying network structure and the biological aspects that influence its stability is crucial to understanding ecosystem *** used antagonistic anuran interactions-predator-prey and host-parasite-to assess structural patterns and to identify the key anuran species structuring these *** tested whether anuran body-size and life-habit are related to their roles in these *** collected individuals of 9 species of anurans from an area of the Atlantic Forest in Brazil and identified their prey and helminth *** used network(modularity,specialization,and nestedness)and centrality metrics(degree,closeness,and betweenness)to identify the role of anuran species in both *** then evaluated whether anuran body-size or life-habit were related to anuran centrality using generalized linear mixed *** networks formed specialized interactions in compartments composed by key species from different *** our networks,anurans with rheophilic and cryptozoic habit are central in predator-prey networks,and those with larger body size and arboreal and cryptozoic habit in the host-parasite *** study represents a step towards a better understanding of the influential factors that affect the structure of anuran antagonist networks,as well as to recognize the functioning roles of anuran species.

关键词： diet disease food web helminth infection network centrality

The ρ-variation of the Hermitian Riesz Transform

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Acta Mathematica Sinica,English Series 2010年第10期26卷 1827-1838页

作者： Raquel CRESCIMBENI Francisco Javier MARTíN-REYES Alberto de la torre José L.torreA departamento de Matemática Universidad Nacional del Comahue Facultad de Economía y Administración departamento de Análisis Matemático Facultad de Ciencias Universidad de Málaga Facultad de Ciencias Universidad Autónoma de Madrid ICMAT-CSIC-UAM-UCM-UC3M

In this paper we prove the behaviour in weighted Lp spaces of the oscillation and variation of the Hilbert transform and the Riesz transform associated with the Hermite operator of dimension 1. We prove that this operator maps LP（R, w（x）dx） into itself when w is a weight in the Ap class for 1 〈 p 〈 ∞. For p = 1 we get weak type for the A1 class. Weighted estimated are also obtained in the extreme case p = ∞.

关键词： Oscillation-p-variation-singular integral-Hermite operator

Use of a lyophilized bovine pericardium graft to repair tunical defect in patients with Peyronie＇s disease： experience in a clinical setting

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Asian Journal of Andrology 2017年第3期19卷 316-320页

作者： Javier Romero Otero Borja garcia Gomez Jose Medina Polo Carlos Pascual Mateoe Silvia garcia Barreras Eduard garcia Cruz Javier de la Riva de la Vifia Alfredo Rodriguez Antolin 12 de Octubre University Hospital Department of Urology Madrid Spain Monteprincipe University Hospital Department of Urology Madrid Spain Clinic Hospital Department of Urology Barcelona Spain

Many different materials are available for grafting during surgery for Peyronie＇s disease （PD）. To study the outcomes associated with the use of a lyophilized bovine pericardium graft （Peri-Guard） to repair tunical defects in patients with PD, descriptive study of 43 patients with disabling penile curvature was performed. Curvature was measured before and after the intervention using a standardized procedure. Surgical technique was plaque excision and grafting of the tunical defect carried out by a single surgeon. A lyophilized bovine pericardium patch was used for grafting. We measured the change in penile curvature and length, the ability to perform successful sexual intercourse without further pharmacological or surgical treatment, and the satisfaction with treatment. Follow-up data were available for a total of 41 patients. Median age was 50 years （IQR 48-52）; mean follow-up time was 14 ± 6 months. Complete penile straightening was achieved in 33 patients （80.5%） and five patients （12.2%） had curvature under 20. Three months after surgery and stretching therapy, mean （s.d.） flaccid penile length increased from 11.2 ± 2.8 cm to 12.1 ± 2.9 cm （P = 0.062）. Seventy-five percentage of patients reported being able to achieve successful intercourse without further treatment. Eighty-five percentage of patients reported to be satisfied with the treatment. There was no evidence of tissue rejection or infection, and only four patients suffered an adverse event. Plaque excision and grafting of the tunical defect with lyophilized bovine pericardium seems to be a safe and effective treatment for patients with PD.

关键词： penile curvature pericardium patch Peyronie's disease surgical treatment

Wireless capsule endoscopy: Perspectives beyond gastrointestinal bleeding

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World Journal of Gastroenterology 2014年第42期20卷 15664-15673页

作者： Eduardo Redondo-Cerezo Antonio Damián Sánchez-Capilla Paloma de la torre-Rubio Javier de Teresa Endoscopy Unit Department of Gastroenterology University Hospital Virgen de Las Nieves department of Gastroenterology University Hospital Virgen de Las Nieves

Wireless capsule endoscopy(CE) is a technology developed for the endoscopic exploration of the small bowel. The first capsule model was approved by the Food and Drug Administration in 2001, and its first and essential indication was occult gastrointestinal(GI) bleeding. Over subsequent years, this technology has been refined to provide superior resolution, increased battery life, and capabilities to view different parts of the GI tract. Indeed, cases for which CE proved useful have increased significantly over the last few years, with new indications for the small bowel and technical improvements that have expanded its use to other parts of the GI tract, including the esophagus and colon. The main challenges in the development of CE are new devices with the ability to provide therapy, air inflation for a better vision of the small bowel, biopsy sampling systems attached to the capsule and the possibility to guide and move the capsule with an external motion control. In this article we review the current and new indications of CE, and the evolving technological changes shaping this technology, which has a promising potential in the coming future of gastroenterology.

关键词： Wireless capsule endoscopy Obscure gastrointestinal bleeding Small bowel tumors Colon capsule endoscopy Esophageal capsule endoscopy

Frequent low dose alcohol intake increases gastric cancer risk: the Health Examinees-Gem (HEXA-G) study

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Cancer Biology & Medicine 2022年第8期19卷 1224-1234页

作者： Hwi-Won Lee Dan Huang Woo-Kyoung Shin Katherine de la torre Minkyo Song Aesun Shin Jong-Koo Lee Daehee Kang department of Biomedical Sciences Seoul National University Graduate SchoolSeoul 03080Korea department of Preventive Medicine Seoul National University College of MedicineSeoul 03080Korea Integrated Major in Innovative Medical Science Seoul National University Graduate SchoolSeoul 03080Korea department of Family Medicine Seoul National University HospitalSeoul 03080Korea

Objective:Epidemiological studies indicate that alcohol increases gastric cancer(GC)risk,yet most studies have focused on heavy alcohol intake,leaving other factors understudied.A comprehensive investigation of the effects of the frequency and amount of alcohol intake may help elucidate the GC risk associated with drinking ***:The Health Examinees-Gem(HEXA-G)study,a community-based large-scale prospective cohort study,enrolled Korean adults 40–69 years of age between the years 2004 and *** GC cases were identified through linkage to Korea Central Cancer Registry data until december 31,***-reported questionnaires were used to survey alcohol consumption-related factors(duration,frequency,amount,and type of alcoholic beverages).The frequency and amount of alcohol consumption were combined to explore GC risk according to 4 drinking patterns:“infrequent-light”,“frequent-light”,“infrequent-heavy”,and“frequent-heavy”.We used Cox proportional hazard models to estimate the adjusted hazard ratios(HRs)and 95%confidence intervals(CIs),and investigate the relationship between alcohol intake and GC ***:A total of 128,218 participants were included in the *** an average follow-up period of 8.6 years,462 men and 385 women were diagnosed with *** men,current drinkers showed a 31%greater risk of GC than non-drinkers(HR 1.31,95%CI 1.03–1.66),whereas no significant association was observed in *** men,GC risk was associated with a higher frequency(P trend 0.02)and dose of ethanol intake in grams(P trend 0.03).In men,the“frequent-light”(≥5 times/week andlationship between alcohol and GC in detai

关键词： Gastric cancer alcohol consumption drinking behavior prospective cohort Health Examinees-Gem(HEXA-G)study

Breaking paradigms: Long non-coding RNAs forming gene fusions with potential implications in cancer

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Genes & Diseases 2024年第3期11卷 311-323页

作者： David Sanchez-Marin Macrina Beatriz Silva-Cazares Fany Iris Porras-Reyes Rebeca garcia-Roman Alma D.Campos-Parra Posgrado en Ciencias Biologicas Facultad de MedicinaUniversidad Nacional Autonoma de MexicoCiudad de MexicoC.P.04360Mexico Unidad Academica Multidisciplinaria Region Altiplano Universidad Autonoma de San Luis Potost(UASLP)Carretera a Cedral Km 5+600Ejido San Jose de la TrojesMatehualaSan Luis PotosiC.P.78760Mexico Servicio de Anatomia Patologica Instituto Nacional de Cancerologia(INCan)Nino JesuisTlalpanCiudaddeMexicoC.P.14080Mexico Instituto de Salud Publica Universidad Veracruzana(UV)Av.Dr LuisDr.Castelazo Ayala s/nCol.Industrial AnimasXalapaVeracruzC.P.91190Mexico

Long non-coding RNAs(lncRNAs)are non-coding RNAs longer than 200 nucleotides with dynamic regulatory *** interact with a wide range of molecules such as DNA,RNA,and proteins to modulate diverse cellular functions through several mechanisms and,if deregulated,they can lead to cancer development and ***,it has been described that IncRNAs are susceptible to form gene fusions with mRNAs or other IncRNAs,breaking the paradigm of gene fusions consisting mainly of protein-coding ***,their biological significance in the tumor phenotype is still ***,their recent identification opens a new line of research to study their biological role in tumor-igenesis,and their potential as biomarkers with clinical relevance or as therapeutic *** present study aimed to review the IncRNA fusions identified so far and to know which of them have been associated with a potential *** address the current challenges to deepen their study as well as the reasons why they represent a future therapeutic window incancer.

关键词： Cancer Genefusions IncRNAs ncRNAs Therapy

Incidence, prevalence, and demographic characteristics of ocular cicatricial pemphigoid in Colombia: data from the National Health Registry 2009-2019

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International Journal of Ophthalmology(English edition) 2021年第11期14卷 1765-1770页

作者： Carlos Cifuentes-González Stefania Amaris-Martínez Juliana Reyes-Guanes Pilar Uribe-Reina Alejandra de-la-torre Neuroscience Research Group Escuela de Medicina y Ciencias de la SaludUniversidad del RosarioBogota 111221Colombia Escuela Barraquer Research Group Escuela Superior de Oftalmología del Instituto Barraquer de AméricaBogota 110111Colombia

AIM:To provide an epidemiological characterization of ocular cicatricial pemphigoid(OCP)in ***:We conducted a cross-sectional study using *** applied the specific code of the International Classification of Diseases for Ocular Pemphigoid,from 2009-2019 to estimate prevalence,incidence,and the demographic status of the disease in ***:The estimated average prevalence was 0.22 per 1000000 inhabitants,and the estimated average incidence was 0.24 per 1000000 *** a female predominance of 62.5%,and a male/female ratio of 1:*** group of patients diagnosed with the disease after the age of 80 presented the highest *** departments with the highest prevalence were Antioquia,Bogotá,and ***:There are important differences between worldwide and Colombian prevalence and incidence data,which may be related to genetic and epigenetic factors,and the possible underdiagnosis of the *** to the results,OCP is an extremely rare disease in ***,it is important to encourage awareness of the disease due to its devastating consequences.

关键词： ocular cicatricial pemphigoid epidemiology incidenee ophthalmology Colombia autoimmune diseases