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Colon capsule endoscopy

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World Journal of Gastroenterology 2008年第34期14卷 5265-5268页

作者： ignacio fernandez-urien Cristina Carretero Ana Borda Miguel Muoz-Navas Department of Gastroenterology University of Navarra

Wireless capsule endoscopy has become the first imaging tool for small bowel examination. Recently, new capsule endoscopy applications have been developed, such as esophageal capsule endoscopy and colon capsule endoscopy. Clinical trials results have shown that colon capsule endoscopy is feasible, accurate and safe in patients suffering from colonic diseases. It could be a good alternative in patients refusing conventional colonoscopy or when it is contraindicated. Upcoming studies are needed to demonstrate its utility for colon cancer screening and other indications such us ulcerative colitis. Comparative studies including both conventional and virtual colonoscopy are also required.

关键词： Capsule endoscopy Colon Polyp Colon cancer Screening Colonoscopy

Role of videocapsule endoscopy for gastrointestinal bleeding

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World Journal of Gastroenterology 2008年第34期14卷 5261-5264页

作者： Cristina Carretero ignacio fernandez-urien Maite Betes Miguel Muoz-Navas Department of Gastroenterology University of Navarra

Obscure gastrointestinal bleeding (OGIB) is defi ned as bleeding of an unknown origin that persists or recurs after negative initial upper and lower endoscopies. Several techniques, such as endoscopy, arteriography, scintigraphy and barium radiology are helpful for recognizing the bleeding source; nevertheless, in about 5%-10% of cases the bleeding lesion cannot be determined. The development of videocapsule endoscopy (VCE) has permitted a direct visualization of the small intestine mucosa. We will analyze those techniques in more detail. The diagnostic yield of CE for OGIB varies from 38% to 93%, being in the higher range in those cases with obscure-overt bleeding.

关键词： Capsule endoscopy Bleeding Small bowel Obscure Hemorrhage

Z-line examination by the PillCam^(TM) SB:Prospective comparison of three ingestion protocols

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World Journal of Gastroenterology 2010年第1期16卷 63-68页

作者： ignacio fernandez-urien Erika Borobio Inmaculada Elizalde Rebeca Irisarri Juan Jose Vila Jesus Maria Urman Javier Jimenez Department of Gastroenterology Hospital of Navarra

AIM:To evaluate the Z-line visualization by the PillCamTM SB2 using three different ingestion protocols. METHODS:Ninety consecutive patients undergoing small bowel capsule endoscopy(SBCE)between January and May 2008 were included in the study. They swallowed the capsule in the standing(Group A= 30),supine(Group B=30)and right supine positions (Group C=30).Baseline patient characteristics, difficulties in capsule ingestion,esophageal transit times(ETT)and Z-line visualization were noted. RESULTS:No significant differences were found between the groups with regard to baseline patient characteristics,ingestion difficulties and complete SB examinations(P>0.05).At least 1 frame of the Z-line was detected in 15.8%,46.7%and 90%of patients in groups A,B and C,respectively(P<0.001).The average number of Z-line images was 0.21±0.53,3.23 ±6.59 and 5.53±7.55 and the mean%of the Z-linedetected was 71.3,25.1 and 8.3,in groups A,B and C, respectively(both P<0.001).ETT times were longer in the supine group followed by the right supine and the standing groups(median of 237 s vs 64 s and 39 s, respectively;P<0.001). CONCLUSION:Z-line visualization in patients undergoing SBCE can be accurately achieved in most cases when the capsule is swallowed in the right supine position.

关键词： Barrett Capsule endoscopy Esophagus Gastroesophageal reflux disease Ingestion Varices Z-line

Capsule endoscopy capture rate: Has 4 frames-per-second any impact over 2frames-per-second?

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World Journal of Gastroenterology 2014年第39期20卷 14472-14478页

作者： ignacio fernandez-urien Cristina Carretero Erika Borobio Ana Borda Emilio Estevez Sara Galter Begoa Gonzalez-Suarez Benito Gonzalez Marisol Lujan Jose Luis Martinez Vanessa Martínez Pedro Menchén Javier Navajas Vicente Pons Cesar Prieto Julio Valle Department of Gastroenterology Hospital de Navarra 31008 Pamplona Spain Department of Gastroenterology Clínica Universidad de Navarra 31008 Pamplona Spain Department of Gastroenterology Hospital Juan Canalejo 26131 La Coru?a Spain Department of Gastroenterology Hospital de Tarrasa 08509 Barcelona Spain Department of Gastroenterology Hospital del Mar 08509 Barcelona Spain Department of Gastroenterology Hospital General de Valencia 46367 Valencia Spain Department of Gastroenterology Hospital Puerta de Hierro 28816 Madrid Spain Department of Gastroenterology Hospital La Fe 46367 Valencia Spain Department of Gastroenterology Hospital Gregorio Mara?ón 28816 Madrid Spain Department of Gastroenterology Complejo Hospitalario de Toledo 45591 Toledo Spain

AIM: To compare the current capsule and a new prototype at 2 and 4 frames-per-second, respectively, in terms of clinical and therapeutic impact.

关键词： Capsule endoscopy Small bowel Diagnostic accuracy Frames Lesions Landmarks

Endoscopic ultrasonography-guided celiac plexus neurolysis in patients with unresectable pancreatic cancer: An update

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World Journal of Gastrointestinal Endoscopy 2021年第10期13卷 460-472页

作者： Guillermo Pérez-Aguado Diego Martinez-Acitores de la Mata Carlos Marra-López Valenciano ignacio fernandez-urien Sainz Department of Gastroenterology Complejo Hospitalario Insular Materno Infantil de Gran CanariaLas Palmas de Gran CanariaLas Palmas 35016Spain Department of Gastroenterology Endoscopy UnitComplejo Hospitalario de Navarra CHNPamplona Navarra 31008Spain Department of Gastroenterology Endoscopy UnitAgencia Sanitaria Costa del SolMálaga 29603Spain

Pancreatic cancer produces disabling abdominal pain,and the pain medical management for pancreatic cancer is often challenging because it mainly relies on the use of narcotics(major opioids).However,opioids often provide suboptimal pain relief,and the use of opioids can lead to patient tolerance and several side effects that considerably reduce the quality of life of pancreatic cancer ***-guided celiac plexus neurolysis(EUS-CPN)is an alternative for pain control in patients with nonsurgical pancreatic cancer;EUS-CPN consists of the injection of alcohol and a local anesthetic into the area of the celiac plexus to achieve chemical ablation of the nerve ***-CPN via the transgastric approach is a safer and more accessible technique than the percutaneous *** have reviewed most of the studies that evaluate the efficacy of EUSCPN and that have compared the different approaches that have been performed by *** efficacy of EUS-CPN varies from 50%to 94%in the different studies,and EUS-CPN has a pain relief duration of 4–8 *** factors are involved in its efficacy,such as the onset of pain,previous use of chemotherapy,presence of metastatic disease,EUS-CPN technique,type of needle or neurolytic agent used,*** to this review,injection into the ganglia may be the best technique,and a good visualization of the ganglia is the best predictor for a good EUS-CPN response,although more studies are ***,any of the 4 different techniques could be used to perform EUS-CPN effectively with no differences in terms of complications between the techniques,but more studies are *** effect of EUS-CPN on pain improvement,patient survival and patient quality of life should be evaluated in well-designed randomized clinical *** research also needs to be performed to clarify the best time frame in performing a EUS-CPN.

关键词： Pancreatic cancer Endosonography Celiac plexus neurolysis Opioids Echoendoscopy

Endoscopic ultrasound-guided drainage of pelvic collections and abscesses

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World Journal of Gastrointestinal Endoscopy 2010年第6期2卷 223-227页

作者： ignacio fernandez-urien Juan J Vila Francisco JavierJimenez Endoscopy Unit Gastroenterology DepartmentHospital de Navarra

Pelvic abscesses are usually the end stage in the progression of an *** may occur from surgical complications,generalized abdominal infections such as appendicitis or diverticulitis,or from localized infections such as pelvic inflammatory disease or inflammatory bowel *** surgery has been considered as the treatment of choice by some authors,pelvic abscesses can be managed by non-invasive methods such as ultrasound and computed tomography-guided *** development of therapeutic linear echoendoscopes has allowed the endoscopist to perform therapeutic ***,endoscopic ultrasonography(EUS)-guided drainage of pelvic collections has been demonstrated to be feasible,efficient and *** allows the endoscopist to insert stents and drainage catheters into the abscess cavity which drains through the large *** article reviews technique, current results and future prospects of EUS-guided drainage of pelvic lesions.

关键词： Endoscopic ultrasound Abscess Collection Pelvis Drainage

Integrating Levels of Hierarchical Organization in Porous Organic Molecular Materials

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Nano-Micro Letters 2024年第5期16卷 134-153页

作者： Jesus Ferrando‑Soria Antonio fernandez Instituto de Ciencia Molecular(ICMol) Universidad de Valencia46980 ValenciaSpain School of Science Loughborough UniversityLoughborough LE113TUUK

Porous organic molecular materials(POMMs)are an emergent class of molecular-based materials characterized by the formation of extended porous frameworks,mainly held by non-covalent *** represent a variety of chemical families,such as hydrogen-bonded organic frameworks,porous organic salts,porous organic cages,C-H···πmicroporous crystals,supramolecular organic frameworks,π-organic frameworks,halogen-bonded organic framework,and intrinsically porous molecular *** some porous materials such as zeolites and metal organic frameworks,the integration of multiscale has been adopted to build materials with multifunctionality and optimized ***,considering the significant role of hierarchy in porous materials and the growing importance of POMMs in the realm of synthetic porous materials,we consider it appropriate to dedicate for the first time a critical review covering both ***,we will provide a summary of literature examples showcasing hierarchical POMMs,with a focus on their main synthetic approaches,applications,and the advantages brought forth by introducing hierarchy.

关键词： Porous organic molecular materials Hierarchy Hydrogen-bonded organic frameworks Porous cages Fullerene

Generation of lossy mode resonances(LMR)using perovskite nanofilms

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Opto-Electronic Advances 2024年第2期7卷 33-40页

作者： Dayron Armas ignacio R.Matias M.Carmen Lopez-Gonzalez Carlos Ruiz Zamarreño Pablo Zubiate ignacio del Villar Beatriz Romero Electrical Electronic and Communications Engineering DepartmentPublic University of NavarraPamplona 31006Spain Institute of Smart Cities(ISC) Public University of NavarraPamplona 31006Spain Experimental Science and Technology School Rey Juan Carlos UniversityMostoles 28933Spain

The results presented here show for the first time the experimental demonstration of the fabrication of lossy mode resonance(LMR) devices based on perovskite coatings deposited on planar waveguides. Perovskite thin films have been obtained by means of the spin coating technique and their presence was confirmed by ellipsometry, scanning electron microscopy, and X-ray diffraction testing. The LMRs can be generated in a wide wavelength range and the experimental results agree with the theoretical simulations. Overall, this study highlights the potential of perovskite thin films for the development of novel LMR-based devices that can be used for environmental monitoring, industrial sensing, and gas detection, among other applications.

关键词： perovskite thin films slab waveguide lossy mode resonance

Experimental implementation of phase triplicator gratings in a spatial light modulator

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Chinese Optics Letters 2024年第2期22卷 64-69页

作者：高尚 María del Mar Sánchez-López ignacio Moreno Instituto de Bioingeniería Universidad Miguel HernándezElche 03202Spain Departamento de Física Aplicada Universidad Miguel HernándezElche 03202Spain Departamento de Ciencia de Materiales Óptica y Tec.Electr´onicaUniversidad Miguel HernándezElche 03202Spain

In this work,we compare different methods for implementing a triplicator,a phase grating that generates three equiintense diffraction *** design with optimal efficiency features a continuous phase profile,which cannot be easily reproduced,and is typically affected by *** compare its performance with binary and sinusoidal phase *** also analyze the effect of quantizing the phase ***,a random approach is adopted to eliminate the additional harmonic *** all cases,a liquid-crystal-on-silicon spatial light modulator is employed to experimentally verify and compare the different approaches.

关键词： diffraction gratings phase modulation triplicator spatial light modulators