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Zika. a. a. emergent epidemic

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a.ia. Pa.ific Journa. of Tropica. Medicine 2016年第8期9卷 701-708页

作者： Bra.ra.Wa.id a.ja. a.i Sha.ia.Ra.ique Muha.ma. idrees Centre for a.plied Molecula. Biology 87-West Canal Bank Road Thokar Niaz Baig University of the Punjab

Zika.virus is a.new globa. threa. for 2016 tha. ha. been swept to a.most a.l a.erica. a.d is now posing serious threa.s to the entire *** dea.ly virus is pla.ing ha.oc to unborn lives beca.se of its reported a.socia.ion with upsurge of feta. deforma.ion ca.led microcepha.y a.d neuropa.hic disorders including Guilla.n-Ba.ré*** toda.,there is no va.cine prospect,a.tivira. thera.y or licensed medica. countermea.ures to curb the tera.ogenic outcomes of this destructive vira. ***,trea.ment,chronicity a.d pa.hogenesis a.e still va.ue a.d ***,this review a.ticle a.dresses a.l the a.pects rela.ed to this disea.e to mitiga.e the explosive rise in Zika.virus infection.

关键词： ZIKV Neurologica. complica.ions Pa.hogenesis Future prospects

a.va.ces in resea.ch on Zika.virus

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a.ia. Pa.ific Journa. of Tropica. Medicine 2017年第4期10卷 301-312页

作者： a.ja. a.i Bra.ra.Wa.id Sha.ia.Ra.ique Muha.ma. idrees Centre for a.plied Molecula. Biology University of the Punjab Vice Cha.cellor Ha.a.a.University

Zika.virus(ZIKV) is ra.idly sprea.ing a.ross the a.erica.a.d its deva.ta.ing outcomes for pregna.t women a.d infa.ts ha.e driven this previously ignored pa.hogen into the *** ma.ifesta.ions a.e fever,joint pa.n or ra.h a.d *** of ZIKV sta.ted with a.first outbrca. in the Pa.ific a.ca.in 2007.a.second la.ge outbrea. occurred in the Pa.ific in 2013/2014 a.d subsequently the virus sprea. in other Pa.ific *** of explosive globa. pa.demic a.d severe clinica. complica.ions linked with the more immedia.e a.d recurrent epidemics necessita.e the development of a. effective *** va.cine pla.forms such a. DNa.va.cine,recombina.t subunit *** purified ina.tiva.ed va.cine,a.d chimeric va.cines ha.e shown potent effica.y in ritro a.d in rim ***,number of drugs such a. ***008 a.d 7-DMa.a.e rea.y to enter pha.e I clinica. tria. beca.se of proven a.ti-ZIKV *** ba.ed a.tibodies offer promise a. a. intervention effective for use in pregna.t *** this review,we describe the a.va.ces in resea.ch on ZIKV such a. resea.ch stra.egies for the development of a.tivira. drugs & va.cines,molecula. evolution,epidemiology emergence,neurologica. complica.ions a.d other tera.ogenic outcomes a. well a. pa.hogenesis.

关键词： Zika.virus Molecula. evolution Neurologica. complica.ions Tra.smission Dia.nosis Pa.hogenesis

Novel Steroida. （6R）-Spiro-1,3,4-thia.ia.oline Deriva.ives a. a.ti-ba.teria. a.ents

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Chinese Journa. of Chemistry 2012年第8期30卷 1901-1905页

作者： khan Sa.ma. a. a.iri, a.dulla. M. Chemistry Depa.tment Faculty of Science King Abdulaziz University P.O. Box 80203 Jeddah 21589 Saudi Arabia Center of Excellence for a.va.ced Ma.eria.s Resea.ch King Abdulaziz University Jeddah 21589 P.O. Box 80203 Saudi Arabia

Novel steroida. （6R）-spiro-1,3,4-thia.ia.oline deriva.ives ha.e been synthesized by the cycliza.ion of steroida. thiosemiea.ba.ones. Thiosemica.ba.ones ha.e been synthesized by the rea.tion of steroida. ketones with thiosemi- ca.ba.ide. a.l the compounds ha.e been cha.a.terized by IR, 1H NMR, ma.s a.d elementa. a.a.yses. The a.tiba.teria. a.tivities of these compounds ha.e been first tested in vitro by the disk diffusion a.sa. a.a.nst two Gra.-positive a.d two Gra.-nega.ive ba.teria. a.d then the minimum inhibitory concentra.ion （MIC） va.ues ha.e been determined with the reference of sta.da.d drug a.oxicillin. The results showed tha. steroida. thia.ia.oline de- riva.ives exhibited better a.tiba.teria. a.tivity tha. the steroida. thiosemica.ba.one deriva.ives. Chloro a.d a.etoxy substituents on the 3β-position of the steroida. thia.ia.oline ring increa.ed the a.ti-ba.teria. a.tivity. a.ong a.l the compounds, compounds 7 a.d 8 were found better inhibitors a. compa.ed to the respective drug a.oxicillin.

关键词： steroida. thiosemica.ba.ones steroida. thia.ia.olines cholesterol a.oxicillin a.tiba.teria. a.tivity

Evidence-ba.ed consensus on the dia.nosis, prevention a.d ma.a.ement of hepa.itis C virus disea.e

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World Journa. of Hepa.ology 2015年第3期7卷 616-627页

作者： Ma.rukh a.ba. Sha.een Muha.ma. idrees Division of Molecula. Virology National Centre of Excellence in Molecular Biology University of the Punjab

Hepa.itis C virus(HCV) is a.potent huma. pa.hogen a.d is one of the ma.n ca.ses of chronic hepa.itis round the world. The present review describes the evidenceba.ed consensus on the dia.nosis, prevention a.d ma.a.ement of HCV disea.e. Va.ious techniques, for the detection of a.ti-HCV immunoglobulin G immunoa.sa.s, detection of HCV RNa.by identifying virus-specific molecules nucleic a.id testings, recognition of core a.tigen for dia.nosis of HCV, qua.tita.ive a.tigena.sa., ha.e been used to detect HCV RNa.a.d core a.tigen. a.va.ced technologies such a. na.opa.ticleba.ed dia.nostic a.sa.s, loop-media.ed isotherma. a.plifica.ion a.d a.ta.ers a.d Ortho tra.-C a.sa. ha.e a.so come to the front tha. provides best detection results with grea.er ea.e a.d specificity for detection of HCV. It is of immense importa.ce to prevent this infection especia.ly a.ong the sexua. pa.tners, injecting drug users, mother-to-infa.t tra.smission of HCV, household conta.t, hea.thca.e workers a.d people who get ta.toos a.d piercing on their skin. Ma.a.ement of this infection is intended to era.ica.e it out of the body of pa.ients. Ma.a.ement includes exa.ining the trea.ment(effica.y a.d protection), a.sessment of hepa.ic condition before commencing thera.y, controlling the pa.a.eters upon which dua. a.d triple thera.ies work, monitoring the body a.ter trea.ment a.d a.justing the co-fa.tors. Exa.ining the trea.ment in some specia. groups of people(HIV/HCV co-infected, hemodia.ysis pa.ients, rena. tra.spla.ted pa.ients).

关键词： Hepa.itis C virus Enzyme immunoa.sa. Nucleic a.id testing Loop-media.ed isotherma. a.plifica.ion Susta.ned vira. response Tela.revir Boceprevir Liver tra.spla.t

Fruits Cla.sifica.ion Using Convolutiona. Neura. Network

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Fruits Classification Using Convolutional Neural Network

作者： Muha.ma. idrees 华北电力大学(北京)

学位级别：硕士

Due to the increa.ed globa. food wa.te tha. ha. resulted from ca.eless production,processing,a.d distribution methods,food security ha. become a. increa.ingly hot topic of discussion in modern *** ga.hered from surveys conducted by institutions a.ound the world,such a. the Food Burea. of the US,ha.e a.so ma.e it clea. tha. a. increa.e in food production is required to meet the needs of a.ra.idly expa.ding *** of this highlights the growing importa.ce of optimising a.a.la.le resources to a.d in the effective production a.d ma.a.ement of our food *** a.ricultura. sector ha. rea.ised the importa.ce of detecting spoiled *** fa.mers often wa.te time a.d energy using huma.s to determine which fruits a.e fresh a.d which a.e *** don't get tired of doing the sa.e thing over a.d over a.a.n like huma.s *** a.result,the project proposes a.method for reducing huma. la.our,a. well a. production costs a.d lea. times,in the a.ricultura. sector through the detection of fruit *** fla.ed fruits could ta.nt hea.thy ones if we don't ca.ch them *** of its usefulness in a.toma.ing routine ta.ks a.d improving the qua.ity of the results,deep lea.ning ha. found a.plica.ion in ma.y different *** pa.t of efforts to ensure tha. people a.wa.s ha.e a.cess to sa.e a.d nutritious food,deep lea.ning is being put to use both in the field a.d in the ma.ketpla.e to boost crop yields a.d protect fruit *** gua.a.tee relia.le reports on the qua.ity of fruit sold to consumers,scientists a.e investiga.ing the fea.ibility of using deep lea.ning for in-store inspection a.d gra.ing ***,since visua. eva.ua.ion is the prima.y ba.is for a.purcha.e decision in the ma.ket,it is importa.t to ensure the visua. qua.ity of fruits in order to drive *** a.toma.ic fea.ure lea.ning ca.a.ilities of CNNs ma.e them idea. for ima.e cla.sifica.ion ta.ks like distinguishing between fresh a.d rotten *** pooling la.e

关键词： Fresh a.d Rotten Fruits Fea.ure Extra.tion Fruit Neura. Network Deep Lea.ning Convolution Neura. Network(CNN) Fruit Cla.sifica.ion

a.Proposed Fea.ure Selection Pa.ticle Swa.m Optimiza.ion a.a.ta.ion for Intelligent Logistics--a.Supply Cha.n Ba.klog Elimina.ion Fra.ework

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Computers, Ma.eria.s & Continua 2024年第6期79卷 4081-4105页

作者： Ya.ser Ha.ha.chi a.ma. E.Khedr a.ira.M.idrees College of Computing a.d Informa.ion Technology a. Khula.s Department of Information SystemsUniversity of JeddahJeddah21959Saudi Arabia Fa.ulty of Computers a.d Informa.ion Technology Future University in EgyptCairo11835Egypt

The diversity of da.a.sources resulted in seeking effective ma.ipula.ion a.d *** cha.lenge tha. a.ises from the increa.ing dimensiona.ity ha. a.nega.ive effect on the computa.ion performa.ce,efficiency,a.d sta.ility of *** of the most successful optimiza.ion a.gorithms is Pa.ticle Swa.m Optimiza.ion(PSO)which ha. proved its effectiveness in exploring the highest influencing fea.ures in the sea.ch spa.e ba.ed on its fa.t convergence a.d the a.ility to utilize a.sma.l set of pa.a.eters in the sea.ch *** resea.ch proposes a. effective enha.cement of PSO tha. ta.kles the cha.lenge of ra.domness sea.ch which directly enha.ces PSO *** the other ha.d,this resea.ch proposes a.generic intelligent fra.ework for ea.ly prediction of orders dela. a.d elimina.e orders ba.klogs which could be considered a. a. efficient potentia. solution for ra.sing the supply cha.n *** proposed a.a.ted a.gorithm ha. been a.plied to a.supply cha.n da.a.et which minimized the fea.ures set from twenty-one fea.ures to ten significa.t *** confirm the proposed a.gorithm results,the upda.ed da.a.ha. been exa.ined by eight of the well-known cla.sifica.ion a.gorithms which rea.hed a.minimum a.cura.y percenta.e equa. to 94.3%for ra.dom forest a.d a.ma.imum of 99.0 for Na.ve ***,the proposed a.gorithm a.a.ta.ion ha. been compa.ed with other proposed a.a.ta.ions of PSO from the litera.ure over different *** proposed PSO a.a.ta.ion rea.hed a.higher a.cura.y compa.ed with the litera.ure ra.ging from 97.8 to 99.36 which a.so proved the a.va.cement of the current resea.ch.

关键词： Optimiza.ion pa.ticle swa.m optimiza.ion a.gorithm fea.ure selection logistics supply cha.n ma.a.ement ba.klogs

Photopolymeriza.ion-ba.ed a.ditive ma.ufa.turing of cera.ics:a.systema.ic review

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Journa. of a.va.ced Cera.ics 2021年第3期10卷 442-471页

作者： Sefiu a.ola.i Ra.a.I Dingyu XIONG Shufeng XIONG Fa.g SU Muha.ma. idrees Zha.gwei CHEN a.ditive Ma.ufa.turing Institute Shenzhen UniversityShenzhen 518060China Institute of Microsca.e Optoelectronics Shenzhen UniversityShenzhen 518060China Gua.gdong Key La.ora.ory of Electroma.netic Control a.d Intelligent Robotics College of Mechatronics and Control EngineeringShenzhen UniversityShenzhen 518060China

Conversion of inorga.ic-orga.ic fra.eworks (cera.ic precursors a.d cera.ic-polymer mixtures) into solid ma.s cera.ic structures ba.ed on photopolymeriza.ion process is currently receiving plentiful a.tention in the field of a.ditive ma.ufa.turing (3D printing).Va.ious techniques(e.g.,stereolithogra.hy,digita. light processing,a.d two-photon polymeriza.ion) tha. a.e compa.ible with this stra.egy ha.e so fa. been widely *** is due to their cost-via.ility,flexibility,a.d a.ility to design a.d ma.ufa.ture complex geometric *** pla.forms rela.ed to these techniques ha.e been developed too,in order to meet up with modem technology *** releva.t to this review a.e the cha.lenges fa.ed by the resea.chers in using these 3D printing techniques for the fa.rica.ion of cera.ic *** cha.lenges often ra.ge from sha.e shrinka.e,ma.s loss,poor densifica.ion,cra.king,wea. mecha.ica. performa.ce to undesira.le surfa.e roughness of the fina. cera.ic *** is due to the brittle na.ure of cera.ic *** on the summa.y a.d discussion on the current progress of ma.eria.-technique correla.ion a.a.la.le,here we show the significa.ce of ma.eria. composition a.d printing processes in a.dressing these *** use of a.propria.e solid loa.ing,solvent,a.d precera.ic polymers in forming slurries is suggested a. steps in the right *** a.e indica.ed a. a.other fa.tor pla.ing vita. roles a.d their selection a.d development a.e suggested a. pla.sible wa.s to remove these ba.riers.

关键词： cera.ics photopolymeriza.ion stereolithogra.hy a.ditive ma.ufa.turing 3D printing polymer-derived cera.ics

Successful immunologica. trea.ment of ga.lbla.der ca.cer in India.Ca.e report

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Journa. of Zhejia.g University-Science B(Biomedicine & Biotechnology) 2006年第9期7卷 719-724页

作者： khan Ja.a. a. Ya.IN Sha.min Microbiology Resea.ch La. C-38/Sector 20 Noida Zip 201301 India

Ga.lbla.der ca.cer ha. a.poor outcome beca.se of its a.a.omy a.d loca.ion. Often, the dia.nosis is ma.e very la.e due to its silent course. Post-opera.ed ca.es do respond to chemothera.y but the surviva. is counted in months a.d the qua.ity of life is further ha.pered due to toxicity of drugs. Immunothera.y holds good promise in non-responding ca.cers trea.ed by conventiona. chemothera.eutic a.ents. a.ong va.ious thera.ies, dendritic cell thera.y is growing a. ra.id pa.e due to its a.cepta.le ra.iona.e. It ha. been utilized in trea.ing successfully resected sta.e Ill （T2, N1, M0） ga.lbla.der ca.cer in one of our pa.ients. a.48 yea.s old la.y trea.ed with this thera.y is free of meta.ta.is with ten doses of a.tologous dendritic cell va.cine constructed by utilizing resected tumor lysa.e a.tigen. She ha. received ten doses of thera.y in 14 months of her trea.ment. This thera.y ha. proven to be sa.e a.d without a.pa.ent side effects. The positive clinica. response obta.ned supports tha. a.tologous dendritic cell-ba.ed immunothera.y is a.promising thera.eutic a.proa.h for refra.tory ga.lbla.der ca.cers.

关键词： Ga.lbla.der Ca.cer Dendritic cell Immunothera.y

a.sessment of Primordia. Ra.ionuclides in Pa.ista.i Red Bricks a.d a.socia.ed Ra.ia.ion Doses

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Chinese Physics Letters 2010年第3期27卷 343-346页

作者： K. khan a. Ja.ba. P. a.hter M. Tufa.l H. M. khan Hea.th Physics Division PINSTECH P.O. Box 1482 Nilore Islamabad Pakistan Pa.ista. Institute of Engineering a.d a.plied Sciences P.O. Nilore Islamabad Pakistan Na.iona. Centre of Excellence in Physica. Chemistry University of Peshawar Pakistan

Specific a.tivity of primordia. ra.ionuclides a.d a.socia.ed ra.ia.ion ha.a.ds due to 40K, 226Ra. a.d 232Th ha.e been mea.ured in ba.ked red brick sa.ples, collected from five highly popula.ed a.ea. of the North West Frontier Province of Pa.ista.. For the detection, a.a.ysis a.d da.a.a.quisition, a.high purity germa.ium detector wa. used. a.socia.ed externa. doses were ca.cula.ed using a.Monte Ca.lo neutron photon tra.sport code. a.theoretica. model to determine the ga.ma.dose ra.e a. 1 m height from the floor, ma.e of bricks, wa. employed for the ca.cula.ion of ma.s a.tenua.ion coefficient a.d self-a.sorption in the floor for the ga.ma.energies of these ra.ionuclides a.d their progeny. Monte Ca.lo simula.ion shows tha. in this study the floor, ha.ing more tha. a. effective thickness of 15 cm, contributes very little to the externa. ga.ma.dose ra.e. The va.ues of the externa. dose ra.e a.d a.nua. effective dose a.e found to be much lower tha. the world a.era.e a. well a. from other countries of the world.

关键词： a.celera.ors bea.s a.d electroma.netism Nuclea. physics Instrumenta.ion a.d mea.urement Environmenta. a.d Ea.th science Pa.ticle physics a.d field theory a.trophysics a.d a.tropa.ticles