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Growth control of peptide-nanotube spherulitic films： Experiments and simulations

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Nano Research 2015年第11期8卷 3630-3638页

作者： Netta Hendler Elad Mentovich Balint Korbuly Tamas Pusztai Laszlo Granasy shachar Richter Department of Materials Science and Engineering Faculty of Engineering Tel Aviv University Ramat Aviv Tel Aviv 69978 Israel Center for Nanoscience and Nanotechnology Tel Aviv University Ramat Aviv Tel Aviv 69978 Israel Wigner Research Centre for Physics P.O. Box 49 H- 1525 Budapest Hungary Brunel Centre forAdvanced Solidification Technology Brunel University Uxbridge Middlesex UB8 3PH UK

多层次自己组装(MHSA ) 是为许多复杂结构的自发的形成负责的一个关键过程。因为这个过程的复杂性，然而，内在的机制仍然保持大部分不清楚。因此， MHSA 的更深的理解被要求，特别为经由自底向上的方法论的 MHSA 系统的准备。我们这里... 详细信息

多层次自己组装(MHSA ) 是为许多复杂结构的自发的形成负责的一个关键过程。因为这个过程的复杂性，然而，内在的机制仍然保持大部分不清楚。因此， MHSA 的更深的理解被要求，特别为经由自底向上的方法论的 MHSA 系统的准备。我们这里，试验性地并且理论上出现，肽 nanotube 电影的复杂形成的 MHSA 能完全被操作湿度的试验性的参数控制。而且，我们识别生长前面成核(GFN；在周界的新谷物的形成) 词法进化作为为由有阶段地的相关试验性的观察的观察词法转变的物理背景当模特儿。我们的调查结果显示一个简单方法控制多层次的形态学，为在为实际应用程序构造复杂结构的自底向上的技术的雇用关键。

关键词：实验参数生长控制纳米管薄膜模拟球晶 MRSA 形态演化

Gene environment interaction in periphery and brain converge to modulate behavioral outcomes:Insights from the SP1 transient early in life interference rat model

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World Journal of Psychiatry 2016年第3期6卷 294-302页

作者： Eyal Asor Dorit Ben-shachar Laboratory of Psychobiology Department of PsychiatryRambam Medical Center and B.Rappaport Faculty of MedicineRappaport Family Institute for Research in the Medical Sciences

It is generally assumed that behavior results from an interaction between susceptible genes and environmental stimuli during critical life *** present article reviews the main theoretical and practical concepts in the research of gene environment interaction,emphasizing the need for models simulating real life *** review a novel approach to study gene environment interaction in which a brief post-natal interference with the expression of multiple genes,by hindering the activity of the ubiquitous transcription factor specificity protein 1(Sp1) is followed by later-in-life exposure of rats to ***,this review discusses the role of peripheral processes in behavioral responses,with the Sp1 model as one example demonstrating how specific behavioral patterns are linked to modulations in both peripheral and central physiological *** suggest that models,which take into account the tripartite reciprocal interaction between the central nervous system,peripheral systems and environmental stimuli will advance our understanding of the complexity of behavior.

关键词： Gene-environmental interaction Specificity protein 1 Mithramycin Stress Animal-model Essential amino acids Tryptophan Insulin

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咖啡馆的文化沉淀

设计家 2010年第4期 78-81页

作者： shachar Lulav Oded Rozenkier Alejandro Fajnerman Ofrit Eshel Noga Weiss Levav shachar Tamar Tuzman Maya Eyal Rozenkier 张小千 So Architecture SO建筑事务所

关键词：设计师以色列特拉维夫文化沉淀建筑面积设计学天花板项目名称餐饮室内设计

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Platelets:A possible glance into brain biological processes in schizophrenia

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World Journal of Psychiatry 2012年第6期2卷 124-133页

Schizophrenia is a severe mental disorder, characterized by behavioral, emotional and cognitive disturbances,which commonly follows a chronic course. Diagnostic accuracy, management plans, treatment evaluation and prognosis are dependent on relatively subjective assessments. Despite extensive research and improvement in imaging technology, as well as modern genetic and molecular methodologies, the biological basis of this disease is still unclear. Therefore, there is a need for objective and valid biological markers. Platelets have often been used as a model in neurobiological research. The accessibility of platelets and their similarities with neurons turns them into an attractive candidate to search for biological markers for diagnosis and for unraveling pathophysiological processes relevant to the etiology of brain disorders, including *** present review addresses the main changes in platelet physiology observed in schizophrenia and its response to antipsychotic medication. We summarize numerous studies demonstrating impaired metabolism,uptake and receptor kinetics of schizophrenia-relevantneurotransmitters, abnormalities in membrane derived phospholipids and polyunsaturated fatty acids, as well as dysfunctions in the mitochondria. These changes fit with the various hypotheses raised for the etiology of schizophrenia, including the dopamine-glutamate hypothesis, the autoimmune hypothesis, the polyunsaturated fatty acid hypothesis and the impaired energy metabolism hypothesis. Despite extensive research in platelets, no conclusive reliable biomarker has been identified yet. This review suggests that the clinical heterogeneity and the biological complexity of schizophrenia lead to the inevitable conclusion that biomarkers will be identified only for subgroups characterized according to the different diagnostic criteria. Moreover, any biomarker would have to be an array of interrelated factors or even a set of several such arrays.

关键词： Platelets Schizophrenia Biomarkers

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犹太人的正向心理学

创业家 2014年第6期 73-73页

作者： shachar Caspi 王根旺 Oddysea 案例中心

一直以来,大多数人认为,工作越努力,事业就越成功,而事业越成功,自己就会越开心。然而,实际情况是,每当成功实现一个目标时,人们总会酝酿另外一个更高目标。比如,考取了哈佛大学会很开心,但到了哈佛以后,下一个目标马上就来了。长此以往... 详细信息

一直以来,大多数人认为,工作越努力,事业就越成功,而事业越成功,自己就会越开心。然而,实际情况是,每当成功实现一个目标时,人们总会酝酿另外一个更高目标。比如,考取了哈佛大学会很开心,但到了哈佛以后,下一个目标马上就来了。长此以往,我们永远不可能开心。所以,需要改变这种思考范式。

关键词：心理学犹太教犹太人逾越节以色列

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莱真达冰淇淋与酸乳酪连锁店

现代装饰 2009年第10期 134-134页

作者： shachar Lulav Oded Rozenkier Alejandro Fejnerman Ofrit Eshel 以色列So Architecture公司

莱真达冰淇淋与酸乳酪连锁店新店选址在以色列北部Ramat Ishay工业区内的一个废弃的木工车间。要设计出顾客所期望的轻盈并能使人心情平静的空间，我们所面临的最大挑战是既有天花高度仅有2．3米，并且空间狭长。我们的主要设计思路是... 详细信息

莱真达冰淇淋与酸乳酪连锁店新店选址在以色列北部Ramat Ishay工业区内的一个废弃的木工车间。要设计出顾客所期望的轻盈并能使人心情平静的空间，我们所面临的最大挑战是既有天花高度仅有2．3米，并且空间狭长。我们的主要设计思路是借用两个线性元素来引导顾客进入店的深处，在那里摆放舒适的坐椅。其中一个线性元素是用松木做成的吧台，另一个则是墙上的图案造型。

关键词：连锁店酸乳酪冰淇淋木工车间图案造型以色列工业区空间

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子宫内膜癌Ⅰ级患者的手术分期

世界核心医学期刊文摘（妇产科学分册） 2005年第8期1卷 51-51页

作者： Ben-shachar I. Pavelka J. CohnD.E. J.M.Fowler 王雅楠 Dr.M-210 Starling Loving Hall 320 West 10th Avenue ColumbusOH 43210 United States

OBJECTIVE: To examine the impact of surgical staging of patients presenting with grade 1 endometrial cancer. METHODS: The charts of all patients who presented for surgery for endometrial cancer between March 1997 and July 2003 were analyzed for demographic data, final tumor histology, grade, stage, and complications. RESULTS: A total of 349 patients underwent surgical management for endometrial cancer. Preoperatively, 181 (52%) were identified with grade 1 disease, with a mean age of 61 years (range 27-89). Surgical staging (pelvic ±paraaortic lymphadenectomy) was performed in 82%of cases and was omitted only in cases when disease was apparently confined to the endometrium and surgical risk was high. In staged patients, 3.2%had severe surgical complications. There were 2 perioperative mortalities (1 pulmonary emboli and 1 myocardial infarct). In comparison of pre-and postoperative histology, 19%of patients were upgraded, with 15%grade 2, 0.5%grade 3, 2.5%serous or clear cell, and 1%mixed mesodermal tumor. Lymph node metastases were found in 3.9%of patients presenting with grade 1 endometrial cancer, and 10.5%had extrauterine spread (> IIb). High-risk uterine features, including myometrial invasion more than 1/2, grade 3 lesions, high-risk histologic variants, and/or cervical involvement, were found in 26%of the patients. No patients with stage Ia-IIb endometrioid cancer received adjuvant teletherapy or chemotherapy. Four patients with low-risk uterine features were found to have extrauterine disease. Twelve percent of patients received adjuvant therapy, and 17%avoided teletherapy and/or chemotherapy based on surgical staging. CONCLUSION: Surgical staging in patients presenting with grade 1 endometrial cancer significantly impacted postoperative treatment decisions in 29%of patients. Omitting lymphadenectomy in patients presenting with grade 1 endometrial cancer may lead to inappropriate postoperative management.

关键词：手术分期宫颈浸润淋巴结切除肿瘤组织学透明细胞癌中胚层瘤治疗决策肌层浸润统计学资料外科手术

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透过TRACE揭秘美国国债市场

金融市场研究 2018年第12期78卷 86-89页

作者：道格·布雷米歇尔·德·普特多布里斯拉夫·杜波夫迈克尔·弗莱明彼得·约翰逊柯林·琼斯弗兰克·基恩迈克尔·普利亚莉莎·莱德曼托尼·罗德里格斯欧·莎哈尔陈俊君(编译) 纽约联储市场组美联储理事会货币事务司货币与金融市场美联储理事会货币事务司纽约联储研究与统计组不详

美国国债市场被广泛认为是世界上最具深度、流动性最强的证券市场,在全球经济和美联储货币政策实施中扮演着关键角色。尽管如此,官方部门获取的现货市场交易信息一直有限。正如《联合工作报告》(JSR)所强调的,这一数据缺口在2014年10月1... 详细信息

美国国债市场被广泛认为是世界上最具深度、流动性最强的证券市场,在全球经济和美联储货币政策实施中扮演着关键角色。尽管如此,官方部门获取的现货市场交易信息一直有限。正如《联合工作报告》(JSR)所强调的,这一数据缺口在2014年10月15日国债市场闪崩事件的调查中表现得最为突出。

关键词：国债市场美国证券市场货币政策全球经济交易信息现货市场美联储

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