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Soleus muscle flap for reconstruction of lower extremity *** or glue factory?

Plastic and Aesthetic Research 2022年第1期9卷 596-604页

作者： Katelyn Kondra Christian Jimenez Eloise Stanton idean roohani Jake Becerra Joseph Carey Division of Plastic and Reconstructive Surgery Keck Medicine of USCLos AngelesCA 90033USA

Aim:Soleus muscle flaps have traditionally been a reliable tool in the plastic surgeon’s armamentarium for lower extremity reconstruction and limb *** the modern era,many surgeons prefer free *** study sought to evaluate trends and outcomes of soleus flap reconstruction after lower extremity injury in a large cohort at a Level 1 trauma ***:This is an Institutional Review Board-approved,retrospective chart review that was undertaken at Los Angeles County+University of Southern California Medical Center from 2007 to *** demographics,Gustilo-Anderson fracture classification,flap characteristics,and outcomes were collected and *** of interest included failure rates,postoperative complications,and long-term ambulatory ***:Of 187 local leg flaps,68(36.4%)were soleus flaps,with 84% of soleus flaps performed prior to *** flap loss rate was 0.0%.Eighteen(26.1%)flaps demonstrated>1 complication,including osteomyelitis/hardware infection(n=12),flap revision(n=6),and amputation(n=2).Long-term follow-up demonstrated 35.3% of patients ambulating independently after an average of 7.5±7.2 months,with the remainder needing a wheelchair or walking assistance ***:Although soleus flap loss rate was 0%,the findings demonstrate more infections than expected;this must be considered in light of pre-existing patient comorbidities possibly deterring free flap ***,our results reveal that only 16% of soleus flaps were performed after *** surgeons consider the reconstructive ladder for lower extremity trauma,a rotational soleus muscle flap should not be overlooked in the modern era of free flap tissue transfers and might be a more optimal flap choice in certain patients with multiple comorbidities.

关键词： Trauma lower extremity local flap soleus ambulatory status

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碳纳米管/聚酰胺纳米复合材料的制备及其阻燃和热性能(英文)

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新型炭材料 2015年第5期30卷 397-403页

作者： Meisam Shabanian Mohsen Hajibeygi Mehdi roohani Faculty of Chemistry and Petrochemical Engineering Standard Research Institute (SRI) Faculty of Chemistry Kharazmi University

首先通过壬二酸和双(对-羧苯基)苯基氧化膦直接缩聚反应得到半芳香聚酰胺(PA),采用溶液共混方法,以多壁碳纳米管(CNTs)增强PA得到新型纳米复合材料。通过TG-DSC和微尺度燃烧量热法探讨CNTs对复合材料的热性能和可燃性能的影响。当CNT添... 详细信息

首先通过壬二酸和双(对-羧苯基)苯基氧化膦直接缩聚反应得到半芳香聚酰胺(PA),采用溶液共混方法,以多壁碳纳米管(CNTs)增强PA得到新型纳米复合材料。通过TG-DSC和微尺度燃烧量热法探讨CNTs对复合材料的热性能和可燃性能的影响。当CNT添加量为5%时复合材料的失重率比纯PA提高5%,热分解温度提高70℃。与纯PA相比,复合材料的热释放速率降低,这表明CNTs能提高PA的阻燃性。

关键词：多壁碳纳米管纳米复合材料聚酰胺阻燃

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Nature-inspired topographies on hydroxyapatite surfaces regulate stem cells behaviour

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Bioactive Materials 2021年第4期6卷 1107-1117页

作者： Yogambha Ramaswamy Iman roohani Young Jung No Genevieve Madafiglio Frank Chang Furong Zhao Zufu Lu Hala Zreiqat Biomaterials and Tissue Engineering Research Unit School of Biomedical EngineeringUniversity of SydneySydneyNSW2006Australia Australian Research Centre for Innovative BioEngineering University of SydneySydneyNSW2006Australia School of Chemistry Australian Centre for NanomedicineUniversity of New South WalesSydney NSWAustralia

Surface topography is one of the key factors in regulating interactions between materials and *** topographies presented to cells in vivo are non-symmetrical and in complex shapes,current fabrication techniques are limited to replicate these complex *** this study,we developed a microcasting technique and successfully produced imprinted hydroxyapatite(HAp)surfaces with nature-inspired(honeycomb,pillars,and isolated islands)*** in vitro biological performance of the developed non-symmetrical topographies was evaluated using adipose-derived stem cells(ADSCs).We demonstrated that ADSCs cultured on all HAp surfaces,except honeycomb patterns,presented well-defined stress fibers and expressed focal adhesion protein(paxillin)*** islands topographies significantly promoted osteogenic differentiation of ADSCs with increased alkaline phosphatase activity and upregulation of key osteogenic markers,compared to the other topographies and the control unmodified(flat)HAp *** contrast,honeycomb topographies hampered the ability of the ADSCs to proliferate and differentiate to the osteogenic *** work presents a facile technique to imprint nature-derived topographies on the surface of bioceramics which opens up opportunities for the development of bioresponsive interfaces in tissue engineering and regenerative medicine.

关键词： Stem cell Biomaterials Bioceramics Scaffolds Micropattern Topography

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Global challenge with the SARS-CoV-2 omicron BA.2(B.1.1.529.2)subvariant:Should we be concerned?

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World Journal of Virology 2022年第6期11卷 496-501页

作者： Jalil roohani Masoud Keikha Department of Biotechnology Faculty of MedicineMashhad University of Medical SciencesMashhad 13131-99137Iran Department of Medical Microbiology School of MedicineZahedan University of Medical SciencesZahedanIran

BA.2 is a novel omicron offshoot of severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)that has gone *** is limited knowledge regarding this variant of *** evidence suggests that this variant is more contagious but less severe than previous SARS-CoV-2 ***,there is concern regarding the virus mutations that could influence pathogenicity,transmissibility,and immune evasion.

关键词： SARS-CoV-2 Omicron BA.2 B.1.1.529.2 Subvariant

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Sr-HT-Gahnite支架材料调控脂肪干细胞成骨/成血管分化活性促进大鼠颅骨缺损修复的实验研究

Sr-HT-Gahnite支架材料调控脂肪干细胞成骨/成血管分化活性促进大...

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中华口腔医学会口腔修复学专业委员会第十次全国口腔修复学术大会

作者：王桂芳 Seyed-Iman roohani-Esfahani 张文杰吕凯歌杨光正丁迅 Hala zreiqat 蒋欣泉上海交通大学医学院附属第九人民医院口腔修复科

目的:体外研究Sr-HT-Gahnite支架材料/浸提液对脂肪干细胞的成骨/成血管分化调控作用,体内研究Sr-HT-Gahnite支架材料复合脂肪干细胞用于促进大鼠颅骨缺损修复方法:以TCP/HA为对照组,Sr-HT-Gahnite支架材料为实验组。通过MTT、碱性磷酸...

目的:体外研究Sr-HT-Gahnite支架材料/浸提液对脂肪干细胞的成骨/成血管分化调控作用,体内研究Sr-HT-Gahnite支架材料复合脂肪干细胞用于促进大鼠颅骨缺损修复方法:以TCP/HA为对照组,Sr-HT-Gahnite支架材料为实验组。通过MTT、碱性磷酸酶活性检测、钙盐沉积检测和Real-time PCR(VEGF,ANG-1和HIF-1a)检测等研究Sr-

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