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Biological, clinical and epidemiological features of COVID-19, SARS and MERS and AutoDock simulation of ACE2

Infectious Diseases of Poverty 2020年第4期9卷 10-20页

作者： Xue-Yan Zhang Hao-Jie Huang Dong-Lin Zhuang Moussa ide Nasser Ming-Hua Yang Ping Zhu Ming-Yi Zhao Department of Pediatrics The Third Xiangya HospitalCentral South UniversityChangsha 410013HunanChina Xiangya School of Medicine Central South UniversityChangsha 410013HunanChina Guangdong Cardiovascular Institute Guangdong Provincial People's HospitalGuangdong Academy of Medical SciencesGuangzhou 510100GuangdongChina

Background:The outbreak of coronavirus disease 2019(COVID-19)has caused a public catastrophe and global *** main symptoms of COVID-19 are fever,cough,myalgia,fatigue and lower respiratory tract infection *** all populations are susceptible to the virus,and thebasic reproduction number(R0)is *** fight against COVID-19 should have two aspects:one is the treatment of infected patients,and the other is the mobilization of the society to avoid the spread of the *** treatment of patients includes supportive treatment,antiviral treatment,and oxygen *** patients with severe acute respiratory distress syndrome(ARDS),extracorporeal membrane oxygenation(ECMO)and circulatory support are *** therapy and traditional Chinese medicine have also achieved good *** review is intended to summarize the research on this new coronavirus,to analyze the similarities and differences between COVID-19 and previous outbreaks of severe acute respiratory syndrome(SARS)and Middle East respiratory syndrome(MERS)and to provide guidance regarding new methods of prevention,diagnosis and clinical treatment based on autodock ***:This review compares the multifaceted characteristics of the three coronaviruses including COVID-19,SARS and *** researchers take the COVID-19,SARS,and MERS as key words and search literatures in the Pubmed *** compare them horizontally and vertically which respectively means concluding the individual characteristics of each coronavirus and comparing the similarities and differences between the three ***:We searched for studies on each outbreak and their solutions and found that the main biological differences among SARS-CoV-2,SARS-CoV and MERS-CoV are in ORF1a and the sequence of gene spike coding *** also found that the types and severity of clinical symptoms vary,which means that the diagnosis and nursing measures also require *** addition to

关键词： COVID-19 Coronavirus SARS MERS Autodock

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Assessment of Indoor Microbial Quality of Library’s Premise: Case of Central Library of the University of YaoundéI

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Open Journal of Preventive Medicine 2018年第4期8卷 109-120页

作者： Kengne Gounmadje Landry Nyegue Maximillienne Ascension Djuidje Chatue ide Armelle Gonsu Kamga Hortense Etoa Francois-Xavier Department of Biochemistry University of YaoundeIYaoundeCameroon Department of Microbiology University of YaoundeIYaoundeCameroon Laboratory of Bacteriology CHUYaoundeCameroon

Background: Good indoor air quality is important for human health and comfort, because people spend a most of their time within buildings. Microbial pollution is a key element of indoor air pollution. Bacteria and fungi growing indoors when sufficient moisture is available usually cause indoor air pollution. Methods: This study was conducted to assess the microbial concentration and to identify the main bacteria and fungi in the indoor environment of Central Library of the University of Yaoundé I. A total of 76 samples were taken from indoor air, surfaces and mouldy books. Bioaerosol sampling and air concentration were made by passive air sampling technique using petri dishes containing different culture media and exposed for 30, 60 and 90 min in the morning and afternoon. Sampling of surfaces and mouldy books were made by rubbing using sterile swab. The identification of the isolated microorganisms was based on macroscopic, microscopic and biochemical characters. Results: The concentrations of bacteria and fungi in the indoor environment of Central Library of the University of Yaoundé I ranged between 747 and 2324 CFU/m for the air and 40 and 500 CFU/cm2 for surfaces. In the examined area, the predominant culturable species of microflora were members of the following bacteria genera;Bacillus spp, Staphylococcus spp, Micrococcus spp, Pseudomonas spp, Rhodococcus spp, Enterobacter spp, Klebsiella spp and Escherichia spp and fungi;Aspergillus spp, Penicillium spp, Curvularia spp, Mucor spp, Cladosporium spp, Candida spp Rhodotorula spp, Fusarium spp, Trichophyton spp, Acremonium spp, Aureobasidium spp, Rhizopus spp and Chrysonilia spp. Conclusion: High concentrations of bacteria and fungi were observed in the central library of the University of Yaoundé I. Precautions and safety measures should be taken to reduce microbial pollution at universities libraries by improving libraries ventilation and disinfection.

关键词： Microbial Pollution Library identification Fungi Bacteria

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用酶联免疫吸附试验检测牛血清中抗阿卡班病毒的抗体

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动物检疫 1992年第6期9卷 39-40页

作者： S.ide 郑增忍

本文报道用酶联免疫吸附试验(ELISA)检测牛血清中抗阿卡班病毒的抗体,同时用血凝抑制试验(H1)及中和试验(NT)与之做比较。HmLu-1细胞系来自苍鼠肺组织,生长培养基为Eagle's基础培养基(MEM)含10%胎牛血清、10%磷酸类胰蛋白(月示)肉汁(TPB... 详细信息

本文报道用酶联免疫吸附试验(ELISA)检测牛血清中抗阿卡班病毒的抗体,同时用血凝抑制试验(H1)及中和试验(NT)与之做比较。HmLu-1细胞系来自苍鼠肺组织,生长培养基为Eagle's基础培养基(MEM)含10%胎牛血清、10%磷酸类胰蛋白(月示)肉汁(TPB)、100单位/m1卡那霉素;维持培养基为MEM含10%TPB和卡那霉素。病毒为JaGAr39阿卡班病毒株。用前在HmLu-1细胞上传代,测定毒价,其感染性用TCIDso表示。

关键词：牛血清阿卡班病毒 ELISA 检测

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阿塔卡玛盐湖盐田设计

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化工矿山译丛 1990年第2期 23-27页

作者： ide.,T 朱世云

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Pathogenesis of Cerebral Ischemia Based on brain-heart interaction

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South China Journal of Cardiology 2022年第2期23卷 129-141,152页

作者： YU Chang-jiang Deng Gang Muqaddas Masood OUYANG Qing HE Yin-ru CHEN Ji-mei ZHU Ping Moussa ide Nasser Guangdong Cardiovascular Institute Guangdong Provincial People's HospitalGuangdong Academy of Medical SciencesGuangzhouZhongshan RoadGuangzhouPR China510080 Guangdong Provincial Key Laboratory of Pathogenesis Targeted Prevention and Treatment of Heart DiseaseAdd:106 Zhongshan Er RoadGuangzhouPR China510080

Over the last few years,neuro-cardiology has grown the awareness of the relationship between the brain and the heart,contributing to developing a modern interdisciplinary field of *** enhance the awareness of the relationship between the brain and the heart,we concentrate on the brain function disability that results from cardiac dysfunction and the brain function impairment that results from cardiac *** is usual for patients with cerebral ischemia to be preceded by cardiac *** main triggers of cerebral ischemia involve arrhythmia,atrial fibrillation,etc.,reflecting a strong connection between the heart and the *** ischemia is linked to how the heart and brain communicate and affect each other at the pathophysiological *** formation of the heart-brain axis mechanism is important in its incidence and *** analysis explores the etiology and pathogenesis of cerebral ischemia centered on the heart-brain axis neuronal pathway and the mechanism of the relationship between the heart and brain,which offers important enrichment to the hypothesis of combined care of brain and heart and is extremely useful for gaining new knowledge for research and production of multi-target drugs for the prevention and treatment of cerebral ischemia.

关键词： Brain Heart.neuro-cardiology Cerebral Ischemia

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通过考虑横轴磁化电抗用有限元分析大型汽轮发电机的饱和同步电抗

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国外大电机 2002年第3期 39-44页

作者： K.ide 邹淑英等

本文叙述了一种在稳态运行时考虑d和q轴电路之间的横轴磁化现象的影响来计算同步电机在不同负荷时饱和电抗的方法，该方法在二维磁场分析的基础上能够计算因为横轴磁化现象引起的互电抗xdq.由一台592MVA汽轮发电机在不同负荷时测量和计... 详细信息

本文叙述了一种在稳态运行时考虑d和q轴电路之间的横轴磁化现象的影响来计算同步电机在不同负荷时饱和电抗的方法，该方法在二维磁场分析的基础上能够计算因为横轴磁化现象引起的互电抗xdq.由一台592MVA汽轮发电机在不同负荷时测量和计算的磁场电流值之间吻合表明了分析结果的有效性，显然，定量的精确度要求考虑d轴和q轴电路之间的磁性耦合，其次，通过考虑因为横轴磁化现象引起的互电抗xdq，分析了不同负荷时的稳态电抗，阐明了负载角δ和互电抗xdq之间的关系，及用数字表示了考虑xdq得到的等效同步电抗与不考虑xdq传统定义的同步电抗之间的区别。

关键词：横轴磁化电抗有限元大型汽轮发电机饱和同步电抗

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在不同频带上分析的1997年日本山口地震的震源过程

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世界地震译丛 2000年第1期31卷 53-58页

作者： S.ide 李忠华云南省地震局

使用强地面运动资料的反演分析,构造了1997年日本山口地震的一组震源破裂模型。对低频带和高频带,分别采用合成格林函数和经验格林函数(EGF)。高频模型的滑动区在空间上相应于低频模型的大滑动区边缘,在时间上相应于初始破裂。计算的滑... 详细信息

使用强地面运动资料的反演分析,构造了1997年日本山口地震的一组震源破裂模型。对低频带和高频带,分别采用合成格林函数和经验格林函数(EGF)。高频模型的滑动区在空间上相应于低频模型的大滑动区边缘,在时间上相应于初始破裂。计算的滑动—应力关系显示,高频模型的应力衰减速率更快,并且所有模型在恒定应力水平时几乎没有滑动。

关键词：地震震源过程山口地震日本频带分析

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建筑技艺 2011年第1期17卷 -页

作者： Kotaro ide 李昭君 ARTechnic Architects

为使房子的实用性更强,ARTechnic Architects非常注重营造舒适的居住环境.轻井泽是个避暑胜地,这里很多别墅都是依照游客至少会在此度假生活1个月以上的时间来设定建筑围护结构的物理参数.随着新干线高速铁路的发展,从东京到轻井泽只需... 详细信息

为使房子的实用性更强,ARTechnic Architects非常注重营造舒适的居住环境.轻井泽是个避暑胜地,这里很多别墅都是依照游客至少会在此度假生活1个月以上的时间来设定建筑围护结构的物理参数.随着新干线高速铁路的发展,从东京到轻井泽只需1小时10分钟,所以很多人都会选择周末到此短暂度假.居住的短暂性导致建筑维护的短暂性.

关键词：弯曲表面建筑卧室围护结构

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Safety and efficacy of Dai-kenchu-to in postoperative infants with gastroschisis

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Open Journal of Pediatrics 2012年第4期2卷 272-277页

作者： Kohei Otake Keiichi Uchida Yuhki Koike Mikihiro Inoue Kohei Matsushita Kiyoshi Hashimoto Shozo ide Yuka Nagano Masato Kusunoki Department of Gastrointestinal and Paediatric Surgery Mie University Graduate School of Medicine Mie Japan Department of Pediatric Surgery National Mie Hospital Mie Japan

Purpose: Intestinal dysfunction is a major problem after gastroschisis repair, and causes poor oral intake and poor body weight gain in infants with gastroschisis. Dai-kenchu-to (DKT) is often used in the treatment of gastrointestinal dysfunction in Japan. The purpose of this study was to analyze the effect of DKT on infants with uncomplicated gastroschisis. Methods: In this retrospective cohort study from 1991 to 2009, we assessed 16 infants with uncomplicated gastroschisis. Eight infants received 0.3 g/kg/day of DKT for 12 months (group 1) and 8 infants did not receive DKT (group 2). We analyzed their body weight as an indicator of the effect of DKT. Results: There were no significant differences in the background characteristics. The body weight of group 1 was significantly increased at the ages of 9 months (p = 0.0348) and 12 months (p = 0.0097), compared with group 2. Multivariate analyses revealed that only DKT administration had a significant impact on body weight gain at the ages of 9 months (p = 0.0201) and 12 months (p = 0.0111). No side effects related to DKT were reported. Conclusion: DKT administration might work safely and effectively for improving the body weight gain in infants with uncomplicated gastroschisis.

关键词： Gastroschisis Dai-Kenchu-To Intestinal Dysfunction Body Weight Gain

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建筑技艺 2011年第Z1期 224-227页

作者： Kotaro ide 李昭君 ARTechnic Architects

为使房子的实用性更强,ARTechnic Architects非常注重营造舒适的居住环境。轻井泽是个避暑胜地,这里很多别墅都是依照游客至少会在此度假生活1个月以上的时间来设定建筑围护结构的物理参数。随着新干线高速铁路的发展,从东京到轻井泽只... 详细信息

为使房子的实用性更强,ARTechnic Architects非常注重营造舒适的居住环境。轻井泽是个避暑胜地,这里很多别墅都是依照游客至少会在此度假生活1个月以上的时间来设定建筑围护结构的物理参数。随着新干线高速铁路的发展,从东京到轻井泽只需1小时10分钟,所以很多人都会选择周末到此短暂度假。居住的短暂性导致建筑维护的短暂性。

关键词：弯曲表面建筑卧室围护结构

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