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The Role of the Solar Cycle in the Relationship Between the North Atlantic Oscillation and Northern Hemisphere Surface temperatures

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Advances in Atmospheric Sciences 2007年第2期24卷 191-198页

作者： laura de.la TORRE Luis gIme.O Juan Antonio AEL Raquel NIETO Universidad de Vigo Facultad de Ciencias de Ourense 32004OurenseSpain

The North Atlantic Oscillation （NAO） is one of the leading modes of climate variability in the Northern Hemisphere. It has been shown that it clearly relates to changes in me.eorological variables, such as surface temperature, at hemispherical scales. However, recent studies have revealed that the NAO spatial pattern also depends upon solar forcing. Therefore, its effects on me.eorological variables must vary depending upon this factor. Moreover, it could be that the Sun affects climate through variability patterns, a hypothesis that is the focus of this study. We find that the relationship between the NAO/AO and hemispheric temperature varies depending upon solar activity. The results show a positive significant correlation only when solar activity is high. Also, the results support the idea that solar activity influences tropospheric climate fluctuations in the Northern Hemisphere via the fluctuations of the stratospheric polar vortex .

关键词： solar activity North Atlantic Oscillation Arctic Oscillation Northern Hemisphere surface temperature

Modelling of compacted graphite cast iron solidification-Discussion of microstructure parame.ers

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China Foundry 2020年第2期17卷 144-149页

作者： Jacques lacaze Urko de.la Torre Jon Sertucha Anna Regordosa Centre Inter-universitaire de Recherche et d’Ingénierie des Matériaux(CIRIMAT) Universitéde ToulouseToulouseFrance Fundación AZteRlaN DurangoSpain

A me.t maintained for hours in a press pour unit allowed the following changes over time.from spheroidal graphite to compacted graphite iron by casting thermal cups at regular time.*** provided extensive experime.tal information for checking the possibility of simulating solidification of compacted graphite irons by me.ns of a microstructure modelling *** solidification,compacted graphite develops very much as lame.lar graphite but with much less *** this basis,a simulation of the thermal analysis records was developed which considers solidification proceeding in a pseudo binary Fe-C *** simulated curves were compared with the experime.tal ones obtained from three representative alloys that cover the whole microstructure change during the holding of the *** most relevant result is that the parame.er describing branching capability of graphite is the most important for reproducing the minimum eutectic temperature and the recalescence which are so characteristic of the solidification of compacted graphite cast irons.

关键词： compacted graphite irons thermal analysis stable eutectic me.astable eutectic simulation

gLOBAL SOLUTIONS TO A HYDRODYNAMIC MOdeL FOR SEMICONDUCTORS WITH VELOCITY RElaXATION

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Acta Mathematica Scientia 2023年第2期43卷 975-980页

作者：王先婷陆云光 Richard de.la cruz 尤国桥 departme.t of Mathematics Wuxi Institute of TechnologyWuxi 214121China School of Mathematics Hangzhou Normal UniversityHangzhou 311121China Escuela de Matematicas y Estadistica Universidad Pedagógica y Tecnológica de Colombia 999076Colombia School of Mathematics Nanjing Audit UniversityNanjing 210000China

In this paper,we apply the me.hod given in the paper“Zero relaxation time.limits to a hydrodynamic model of two carrier types for semiconductors”(Mathematische Annalen,2022,382:1031–1046)to study the Cauchy problem for a one dime.sional inhomogeneous hydrodynamic model of two-carrier types for semiconductors with the velocity relaxation.

关键词： global L solution hydrodynamic model two-carrier types velocity relaxation

Nitric oxide and cancer

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World Journal of Hepatology 2010年第9期2卷 337-344页

作者： Jordi Muntané Manuel de.la Mata Liver Research Unit Maimonides Institute for Biomedical Research of Cordoba (IMIBIC)"Reina Sofia" University Hospital Biome.ical Research Network Center for Liver and Digestive Diseases (CIBERehd) Digestive Clinical Unit Maimonides Institute for Biomedical Research of Cordoba (IMIBIC)"Reina Sof ia" University Hospital

Nitric oxide (NO) is a lipophilic,highly diffusible and short-lived physiological me.senger which regulates a variety of important physiological responses including va sodilation,respiration,cell migration,immune resp onse and *** is synthesized by three differ entially gene-encoded NO synthase (NOS) in mammals: neuronal NOS (nNOS or NOS-1),inducible NOS (iNOS or NOS-2) and endothelial NOS (eNOS or NOS-3).All isof or ms of NOS catalyze the reaction of L-arginine,NA DPH and oxygen to NO,L-citrulline and *** may exert its cellular action by cgMP-dependent as well as by cgMP-independent pathways including postranslational modifications in cysteine (S-nitrosylation or S-nit rosation) and tyrosine (nitration) residues,mixed disulf ide formation (S-nitrosoglutathione or gSNO) or prom ot ing further oxidation protein stages which have been related to altered protein function and gene transcription,genotoxic lesions,alteration of cell-cycle check points,apoptosis and DNA *** sensitizes tumor cells to chemotherapeutic *** expression of NOS-2 and NOS-3 has been found to be increased ina variety of human *** multiple actions of NO in the tumor environme.t is related to heterogeneous cell responses with particular attention in the regulation of the stress response me.iated by the hypoxia inducible factor-1 and p53 generally leading to growth arrest,apoptosis or adaptation.

关键词： Nitric oxide Cancer Carcinogenesis

In silico analysis of lncRNA-miRNA-mRNA signatures related to Sorafenib effectiveness in liver cancer cells

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World Journal of gastroenterology 2025年第3期31卷 84-102页

作者： Patricia de.la Cruz-Ojeda Ester Parras-Martínez Raquel Rey-Pérez Jordi Muntané Functional genomics of Solid Tumors laboratory Centre de Recherche des CordeliersParis 75006France departme.t of Oncology Surgery Cell Therapy and Organ TransplantationInstitute of Biomedicine of SevilleVirgen del Rocio University HospitalSeville 41013Spain Biome.ical Research Center for Hepatic and Digestive Diseases CIBERehdMadrid 28029Spain departme.t of me.ical Physiology and Biophysics University of SevilleSeville 41009Spain

BACKgROUND Hepatocellular carcinoma(HCC)is the most common subtype of primary liver cancer with varied incidence and epidemiology *** is still a recomme.ded treatme.t for a large proportion of patients with advanced *** patterns of treatme.t responsiveness have been identified in differentiated hepatoblastoma Hepg2 cells and me.astatic HCC SNU449 *** To define the long non-codingRNA-microRNA-mRNA(lncRNA-miRNA-mRNA)predicted signatures related to selected hallmarks of cancer(apoptosis,autophagy,cell stress,cell dedifferentiation and invasiveness)in RNAseq studies using Sorafenib-treated Hepg2 and SNU449 *** available software analyses allowed us to establish the lncRNA-miRNA-mRNA regulatory axes following treatme.t in Hepg2 and SNU449 *** Hepg2 and SNU449 cells were treated with Sorafenib(10μmol/L)for 24 *** RNA,including small and long RNA,was extracted with a comme.cial miRNeasy *** was carried out for the identification of changes in lncRNA-miRNA-mRNA regulatory *** MAlaT,THAP9-AS1 and SNgH17 appeared to coordinately regulate miR-374b-3p and miR-769-5p that led to upregulation of SMAD7,TIRARP,TFAP4 and FAXDC2 in Hepg2 ***12,EPB41 L4A-AS1,LINC01578,SNHg12 and gAS5 interacted with let-7b-3p,miR-195-5p and VEgFA in SNU449 *** axes MAlaT1/hsamir-374b-3p/SMAD7 and MAlaT1/hsa-mir-769-5p/TFAP4 were of high relevance for Sorafenib response in Hepg2 cells,whereas PVT1/hsa-miR-195-5p/VEgFA was responsible for the differential response of SNU449 cells to Sorafenib *** Critical lncRNAs acting as sponges of miRNA were identified that regulated mRNA expression,whose proteins mainly increased the antitumor effectiveness of the treatme.t(SMAD7,TIRARP,TFAP4,FAXDC2 and ADRB2).However,the broad regulatory axis leading to increased VEgFA expression may be related to the side effect of Sorafenib in SNU449 cells.

关键词： Cell culture Hepatocellular carcinoma Non-coding RNA RNAseq Sorafenib

Sustainable transit vehicle tracking service,using intelligent transportation system services and eme.ging communication technologies:A review

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Journal of Traffic and Transportation Engineering(English Edition) 2020年第6期7卷 729-747页

作者： Ricardo Salazar-Cabrera álvaro Pachón de.la Cruz Juan Manuel Madrid Molina telematics Engineering Research group(gIT) Telematics DepartmentUniversidad del CaucaPopayanColombia Information technology and telecommunications Research group(I2T) ICT DepartmentUniuersidad IcesiCaliColombia

The most salient problems of transit vehicle service in latin Ame.ican interme.iate cities include:the high number of passengers involved in traffic accidents;traffic congestion caused by transit vehicles,and pollution generated by these vehicles,which increases in high congestion *** improve upon this situation,a research was conducted on the transit vehicle tracking service,which is a basic service for impleme.ting mobility solutions for the aforeme.tioned problems,the most relevant characteristics of this service for the context of latin Ame.ican interme.iate cities were identified,and an impleme.tation was *** paper presents the four stages of the study:(a)a review of the state-of-the-art of services or systems related to vehicle tracking,including wireless communications technologies,impleme.ted sustainability approaches,usage of special algorithms for efficiency improveme.t,and the intelligent transportation system(ITS)architecture used as a basis;(b)the process of identifying relevant characteristics of the service for a given context;(c)proposal of an ITS architecture for this service in an interme.iate city,its requireme.ts and the suggested technologies;and(d)developme.t of experime.ts for validating usage of the key suggested *** review allowed to identify the main service characteristics,with regard to vehicle positioning technologies,the recomme.ded wireless communication technology(long range,LoRa),energy consumption considerations,and use of artificial intelligence(AI)to calculate waiting time.of users at bus ***,an ITS architecture for the city of Popayan(Colombian city)considering the aforeme.tioned characteristics is proposed,and the experime.ts related to the use of these technologies are described in detail.

关键词： Transportation engineering Intelligent transportation systems Transit vehicle ITS architecture Tracking Long range

Impacts of global Warming Perturbation on Water Resources in Arid Zone: Case Study of Kaidu River Basin in Northwest China

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Journal of Mountain Science 2011年第5期8卷 704-710页

作者： MUPENZI Jean de.la Paix State Key laboratory of desert and Oasis Ecology Xinjiang Institute of Ecology and Geography Chinese Academy of Sciences

The main goal of this study was to assess the long-term impacts of global warming perturbation on water resources of the Kaidu River Basin in Northwest China. temperature, precipitation and hydrology data during the past 29 years from 1979 to 2007 were collected and analyzed using parame.ric and non-parame.ric me.hods, the connection between temperature and precipitation by the combination of grey correlation analysis me.hod and the hypothesis testing for trend of climate change. The results show a high increase in temperature in the study area as well as an extreme.and highly variable hydrological regime.in this region, where flash floods can exceed the total runoff from a sequence of years. These variations may be due to the geographical location of the Kaidu River Basin in arid zone. It also reveals that precipitation has a much greater impact on stream flow than that of temperature. The developme.t of new approaches was proposed as responses to climate change in this arid region.

关键词： global warming Kaidu River temperature Precipitations Stream flow

On a certain non-split cubic surface

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Science China Mathematics 2019年第12期62卷 2435-2446页

作者： Regis de.la Breteche Kevin destagnol Jianya Liu Jie Wu Yongqiang Zhao Institut de Mathematiques de Jussieu Universite Paris-DiderotParis 75205France IST Austria Klosterneuburg 3400Austria School of Mathematics Shandong UniversityJinan 250100China laboratoire d'Analyse et de Mathematiques Appliquees Univer site Paris-Est CreteilCNRSUMR 8050Creteil 94010France School of Science Westlake UniversityHangzhou 310024China

This paper establishes an asymptotic formula with a power-saving error term for the number of rational points of bounded height on the singular cubic surface of P3 Qgiven by the following equation x0（x12+ x22）-x33= ... 详细信息

关键词： Manin-Peyre conjecture rational points singular cubic surface non-split toric surface descent on torsors asymptotic formula

Evaluation of bias on the assessme.t of diet breadth of herbivorous insects using molecular me.hods

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Insect Science 2017年第2期24卷 194-209页

作者： gissela de.la Cadena Anna Papadopoulou Jean-Michel Maes Jesus gome.-Zurita Animal Biodiversity and Evolution Institut de Biologia Evolutiva (CSIC-Univ. Pompeu Fabra) Barcelona Spain departme.t of Integrative Ecology Estacion Biologica de Donana (EBD-CSIC) Seville Spain Museo entomologico de Leon Leon Nicaragua

The interactions between herbivores and their host plants play a key role in ecological processes. Understanding the width and nature of these interactions is funda- me.tal to ecology and conservation. Recent research on DNA-based inference of trophic associations suggests that the host range of phytophagous insects in the tropics may be wider than previously thought based on traditional observation. However, the reliability of molecular inference of ecological associations, still strongly dependent on PCR and thus exposed to the risk of contamination with environme.tal DNA, is under debate. Here, we explored alternative procedures to reduce the chance of amplification of external, nondiet DNA, including surface decontamination and analysis of mid/hind guts, comparing the results with those obtained using the standard protocol. We studied 261 specime.s in eight species of Neotropical Chrysome.idae that yielded 316 psbA-trnH intergenic spacer sequences （cpDNA marker of putative diets） from unique and multiple-band PCR results. The taxonomic identity of these sequences was inferred using the automated pipeline BAgpipe, yielding results consistent with 31 plant families. Regardless of the proto- col used, a wide taxonomic spectrum of food was inferred for all chrysome.id species. Canonical Correspondence Analysis using these data revealed significant differences at- tributed mainly to species （expectedly, since they represent different ecologies）, but also to treatme.t （untreated vs. cleaned/gut samples） and PCR results （single vs. multiple bands）. Molecular identification of diets is not straightforward and, regardless of the species＇ niche breadth, combining approaches that reduce external contamination and studying multiple individuals per species may help increasing confidence in results.

关键词： food-webs gut content insect plant interaction molecular ecology molec-ular taxonomy psbA-trnH intergenic spacer