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Nanomanufacturing and Metrology 2021年第2期4卷 86-96页

作者： Ryo Sakakibara ichiro yoshida Yuki Kondo Munetoshi Numada Kenichi Yamashita HOSEI University Graduate School 3-7-2 KajinochoKoganei-shiTokyo184-8584Japan Faculty of Science and Engineering HOSEI University3-7-2 KajinochoKoganei-shiTokyo184-8584Japan Faculty of Engineering Chukyo University101-2 YagotohonmachiNagoyaShowa-kuAichi466-8666Japan ISUZU Advanced Engineering Center LTD8 TsuchidanaFujisawa-shiFujisawa-shiKanagawa252-0881Japan

ISO 13565-3 provides an evaluation method for plateau structure surfaces used as sliding surfaces in machine tools and automobile *** evaluation method for plateau structure surfaces of ISO 13565-3 has problems,such as the processing procedure has an ambiguous basis,and the calculation method is not *** existing evaluation method that solves these problems requires the implementation of a difficult *** subsequent evaluation methods,these problems were resolved,and the implementation of complicated calculation algorithms became ***,these methods use algorithms that do not conform to the evaluation method of ISO *** lack of adherence to the ISO standard may hinder their application in the industrial ***,in this study,a new method that conforms to the evaluation method of ISO 13565-3 with a more concise algorithm was *** concluded that this proposed method can contribute to the formation of plateau surfaces and production control in the industrial world.

关键词： Stratified functional properties Plateau surface Surface texture Surface roughness Material probability curve

Verification of Characteristics of Gaussian Filter Series for Surface Roughness in ISO and Proposal of Filter Selection Guidelines

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Nanomanufacturing and Metrology 2021年第2期4卷 97-108页

作者： Yuki Kondo ichiro yoshida Dan Nakaya Munetoshi Numada Hiroyasu Koshimizu HOSEI University 3-7-2 Kajino-choKoganei-shiTokyo184-8584Japan Chukyo University 101-2 Yagotohonmati Showa-kuNagoyaAichi466-8666Japan YYC Solution 3-102-3F Kamiyashiro Meito-kuNagoyaAichi465-0025Japan

In surface roughness measurement,if spikes are included in the primary profile,a problem occurs wherein the Gaussian filter(GF)is unable to extract the shape *** address this problem,the use of a robust filter is ***,ISO16610-31:Gaussian regression filters(GRF)only provide a single method and a few examples,and does not specify the conditions under which the primary profile can be ***,the data presented in the example on robustness in ISO16610-31 do not contain roughness *** actual roughness measurements,no primary profile exists that does not include a roughness *** the characteristics of GRFs are unknown,it is not yet clear which filter should be used for which primary profile,and this is an issue that has been raised at ISO and JIS *** addition,the establishment of filter selection guidelines is necessary at measurement ***,this paper clarifies the characteristics of GF-series filters,summarizes the points to be considered when using them,and identifies the filter that should be selected according to different *** on the results,a figure that visualizes the characteristics of filters and a flowchart regarding which filter should be used are created;these tools,to the best of the authors’knowledge,did not exist prior to this *** is believed that these results will help fulfil the needs of measuring job sites and also aid in filter selection.

关键词： Surface roughness Gaussian filter Robust filter M-estimation method Fast M-estimation method

A Proposal of a Spline Filter that Achieves Both Robustness and Lower Compatibility

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Nanomanufacturing and Metrology 2021年第2期4卷 77-85页

作者： Yuki Kondo Munetoshi Numada Keiya Takahashi ichiro yoshida Hiroyasu Koshimizu HOSEI University 3-7-2 Kajino-choKoganei-shiTokyo184-8584Japan Chukyo University 101-2 Yagotohonmati Showa-kuNagoyaAichi466-8666Japan YYC Solution 3-102-3F Kamiyashiro Meito-kuNagoyaAichi465-0025Japan

A spline filter is used to extract roughness profiles for the measurement of surface texture and is useful when sufficient sections before and after a primary profile could not be *** is because a spline filter could prevent the end effect,which is the fluctuation of output data that occurs around both ends of the primary profile and depends on the width of the weighting function of a *** spline filter is based on the calculation of an inverse matrix instead of the convolution of the weighting function of the *** input data include outliers,the output of a spline filter greatly *** solve this problem,we propose a robust spline ***,output of the robust spline is not in agreement with that of the spline filter when input data do not include ***,the robust spline filter has no lower *** this paper,the"Fast M-estimation Spline Filter(FMSF)"is *** uses the fast M-estimation *** performs robust to input data including outliers,and gives the same output as that of general spline filters to input data without *** value estimated by this method is in agreement with that estimated by the least squares method if no outlier *** order to apply the fast M-estimation method to the spline filter,convolution of weight function is used instead of the inverse *** the input geometry with shear and point-symmetric extensions is pre-processed to prevent the end effect.

关键词： Surface roughness Spline filter Robustness Lower compatibility End effect M-estimation method

Measurement Method of Internal Residual Stress in Plastic Parts Using Terahertz Spectroscopy

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Nanomanufacturing and Metrology 2021年第1期4卷 46-52页

作者： Yusuke Kajihara Rio Takahashi ichiro yoshida Shingo Saito Norihiko Sekine Shuichi Nowatari Shigeo Miyake Institute of Industrial Science The University of TokyoKomaba 4-6-K Meguro-kuTokyoJapan Hosei University Kajino 3-7-2.KoganeiTokyoJapan National Institute of Information and Communications Technology Nukui-Kitamachi 4-2-1KoganeiTokyoJapan Iida Co. LtdNukazawa Mizukami 21-2MotomiyiaFukushimaJapan

Since internal residual stress in polymers causes dimension errors over time,a measurement method for residual stress in polymers,especially in opaque engineering plastics,is strongly *** this study,we propose to utilize terahertz(THz)spectroscopy to non-destructively measure internal residual stress in *** verify the validity of the proposed method,we manufactured polytetrafluoroethylene ring samples with and without residual stress,and studied them with THz time domain spectroscopy *** spectra of samples without residual stress showed almost no polarization difference,whereas spectra of samples with residual stress showed clear polarization *** changes between the samples with and without residual stress were also estimated and it was found that the change had a correlation with THz polarization *** experimental analyses confirm the validity for the proposed non-destructive measurement of residual stress in polymer.

关键词： Engineering plastics Residual stress Polarization Terahertz spectroscopy

A Study on Fast and Robust Vanishing Point Detection System Using Fast M-Estimation Method and Regional Division for In-vehicle Camera

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Journal of Electrical Engineering 2018年第2期6卷 107-115页

作者： Yuki Kondo Munetoshi Numada Hiroyasu Koshimizu ichiro yoshida Faculty of Science and Engineering Hosei University Tokyo 184-8584 Japan Faculty of Engineering Chukyo University Aichi 466-8666 Japan

The vanishing point detection technology helps automatic driving. In this paper, the straight lines on the road associated with the vanishing point are extracted efficiently by using the regional division and angle limitation. And, the vanishing point is detected robustly by using the fast M-estimation method. Proposed method could detect straight-line features associated with vanishing point detection efficient on the road. And the vanishing point was detected exactly by the effect of the fast M-estimation method when the straight-line features not associated with vanishing point detection were detected. The processing time of the proposed method was faster than the camera flame rate （30 fps）. Thus, the proposed method is capable of real-time processing.

关键词： Automatic driving Hough transform fast M-estimation method line detection vanishing point

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四氢生物蝶呤反应性苯丙氨酸羟化酶缺乏症

中国当代儿科杂志 2005年第4期7卷 301-304页

作者： Haruo SHINTAKU Shigeo KURE Toshihiro OHURA Yoshiyuki OKANO Misao OHWADA Naruji SUGIYAMA Nobuo SAKURA ichiro yoshida Makoto YOSHINO Yohichi MATSUBARA Ken SUZUKI Kikumaro AOKI Teruo KITAGAWA 大阪市立大学医学院儿科大阪日本545-8585

目的四氢生物蝶呤(BH4)可以使BH4缺乏症病人的血液苯丙氨酸水平正常化,但是对苯丙酮酸尿症(PKU)病人无效。最近在新生儿PKU筛查中发现了对BH4有反应的轻度PKU患者。本研究将探讨BH4和苯丙氨酸羟化酶(PAH)基因突变在对BH4有反应的轻度PK... 详细信息

目的四氢生物蝶呤(BH4)可以使BH4缺乏症病人的血液苯丙氨酸水平正常化,但是对苯丙酮酸尿症(PKU)病人无效。最近在新生儿PKU筛查中发现了对BH4有反应的轻度PKU患者。本研究将探讨BH4和苯丙氨酸羟化酶(PAH)基因突变在对BH4有反应的轻度PKU和轻度高苯丙酸血症(HPA)患者中的作用。方法对经新生儿PKU筛查中发现的生物蝶呤代谢正常的轻度HPA患者,进行单次(10mg/kg)、4次、1周[20 mg/(kg·d)]的BH4口服负荷试验及长期BH4治疗,评估其对BH4口服负荷试验的反应性。结果在单剂量BH4口服负荷试验中,典型PKU患者的血苯丙氨酸水平没有降低。在单剂量BH4口服负荷试验中血苯丙氨酸水平下降超过20%的患者,在4次BH4口服负荷试验中下降亦超过20%。1周BH4负荷试验确认在单剂量和4次BH4负荷试验中表现出弱反应性的病人对BH4有反应。许多患轻度PKU和轻度HPA且有R241C基因位点的病人,都对BH4治疗有反应。在无BH4反应性的典型PKU病人中未发现R241C、P407S和A373T基因突变。结论1周BH4负荷试验用于诊断BH4反应性PAH缺乏症最为有效。等位基因R241C、P407S和A373T与轻度HPA和轻度PKU病人具有H4反应性有关。BH4治疗是针对轻度HPA和轻度PKU的一种新颖、有效的药物治疗,有望代替限制苯丙氨酸饮食的方法。

关键词：苯丙氨酸尿症四氢生物蝶呤突变基因儿童

Evaluation of interfacial strength by an instrumented indentation method and its application to an actual TBC vane

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Acta Metallurgica Sinica(English Letters) 2011年第2期24卷 109-117页

作者： Yasuhiro YAMAZAKI Shin-ichiro KUGA Toshihiko yoshida Department of Mechanical and Control Engineering Department of Advanced Production Systems Engineering Niigata Institute of Technology Graduate School Ryodensya Co.

The thermal fatigue behaviour of an air plasma sprayed thermal barrier coating was investigated. And also the interfacial strengths of thermal barrier coated specimens subjected to thermal fatigue, as well as a retired TBC vane were also evaluated by means of an instrumented indentation machine. The results indicated that, （1） the TGO grew at the interface during thermal fatigue cycle as a function of the exposure time at elevated temperature; （2） the microcracks were initiated in the top coating and at the interface after thermal cycle tests; （3） the interfacial strength of TBC, which was evaluated by the indentation method, increased with the thermal cycles; （4） the interfacial strength of the retired TBC vane was almost equal with that of the as-sprayed TBC specimen.

关键词： Thermal barrier coating Interfacial fracture toughness Indentation method

Legionella dumoffii Tex-KL Mutated in an Operon Homologous to traC-traD is Defective in Epithelial Cell Invasion

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Biomedical and Environmental Sciences 2016年第6期29卷 424-434页

作者： QIN Tian Iida Ken-ichiro REN Hong Yu ZHOU Hai Jian Shin-ichi yoshida State Key Laboratory for Infectious Disease Prevention and Control National Institute for Communicable Disease Control and Prevention Chinese Center for Disease Control and Prevention beijing 102206 China Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases Hangzhou 310003 Zhejiang China Departments of Bacteriology Faculty of Medical Sciences Kyushu University Higashi-ku Fukuoka 812-8582 Japan

Objective To understand the mechanism of invasion by Legionella dumoffii. Methods The L. dumoffii strain Tex-KL was mutated using the Tn903 derivative, Tn903 d IIlac Z. After screening 799 transposon insertion mutants, we isolated one defective mutant. We then constructed the gene-disrupted mutant, KL16, and studied its invasion of and intracellular growth in He La and A549 cells, and in A/J mice survival experiments. The structure of traC-traD operon was analyzed by RT-PCR. Results The transposon insertion was in a gene homologous to Salmonella typhi tra C, which is required for the assembly of F pilin into the mature F pilus structure and for conjugal DNA transmission. Results from RT-PCR suggested that the traC-traD region formed an operon. We found that when the tra C gene was disrupted, invasion and intracellular growth of L. dumoffii Tex-KL were impaired in human epithelial cells. When mice were infected by intranasal inoculation with a tra C deficient mutant, their survival significantly increased when compared to mice infected with the wild-type strain. Conclusion Our results indicated that the traC-traD operon is required for the invasion and intracellular growth abilities of L. dumoffii Tex-KL in epithelial cells.

关键词： L. dumoffii Tex-KL traC-traD operon Invasion ability Epithelial cells

Transileocolic endovascular treatment by a hybrid approach for severe acute portal vein thrombosis with bowel necrosis:Two case reports

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World Journal of Clinical Cases 2022年第6期10卷 1876-1882页

作者： Sayaka Shirai Tatsuo Ueda Fumie Sugihara Daisuke Yasui Hidemasa Saito Hiroyasu Furuki Shiei Kim Hiroshi yoshida Shoji Yokobori Hiromitsu Hayashi Shin-ichiro Kumita Department of Radiology Nippon Medical School HospitalBunkyo-ku 113-8603TokyoJapan Department of Radiology Nippon Medical School Musashi Kosugi HospitalKawasaki-shi 211-8533KanagawaJapan Department of Gastrointestinal and Hepato-Biliary-Pancreatic Surgery Nippon Medical School Tamanagayama HospitalTama-shi 206-8512TokyoJapan Department of Emergency and Critical Care Medicine Nippon Medical School HospitalBunkyo-ku 113-8603TokyoJapan Department of Gastrointestinal and Hepato-Biliary-Pancreatic Surgery Nippon Medical School HospitalBunkyo-ku 113-8603TokyoJapan

BACKGROUND Acute portal vein thrombosis(PVT)with bowel necrosis is a fatal condition with a 50%-75%mortality *** report describes the successful endovascular treatment(EVT)of two patients with severe *** SUMMARY The first patient was a 22-year-old man who presented with abdominal pain lasting 3 *** second patient was a 48-year-old man who presented with acute abdominal *** contrast-enhanced computed tomography,both patients were diagnosed with massive PVT extending to the splenic and superior mesenteric *** treatment(simultaneous necrotic bowel resection and EVT)was performed in a hybrid operating room(OR).EVTs,including aspiration thrombectomy,catheter-directed thrombolysis(CDT),and continuous CDT,were performed via the ileocolic vein under *** portal veins were patent 4 and 6 mo posttreatment in the 22-year-old and 48-year-old patients,*** Hybrid necrotic bowel resection and transileocolic EVT performed in a hybrid OR is effective and safe.

关键词： Bowel necrosis Endovascular treatment Hybrid operating room Hybrid treatment Portal vein thrombosis Transileocolic approach Case report

A Study on the Reduction of Vibration and Acoustic Noise for Switched Reluctance Motor

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A Study on the Reduction of Vibration and Acoustic Noise for...