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伊朗南部高扎格罗斯浊积放射虫岩亚带的放射虫地层学(英文)

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地球学报 2012年第S1期33卷 18-20页

作者： Ken-ichiro HISADA Yoshihito KAMATA Graduate School of Life and Environmental Sciences University of TsukubaIbraki 305-8572Japan

Zagros orogen extends from the Turkish-Iranian border to NW,to the Makran area in *** to Geological Survey of Iran 100,000 series "Sureyan", "Saadatshahr","Abadeh-E-Tashk" and "Arsenjan",the Zagros orogen comprises th... 详细信息

关键词： Zagros southern Iran radiolarite Cretaceous Jurassic

Scirrhous hepatocellular carcinoma displaying atypical findings on imaging studies

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World Journal of Gastroenterology 2009年第18期15卷 2296-2299页

作者： Soo Ryang Kim Susumu Imoto Taisuke Nakajima Kenji Ando Keiji Mita Katsumi Fukuda Ryo Nishikawa Yu-ichiro Koma Toshiyuki Matsuoka Masatoshi Kudo Yoshitake Hayashi Department of Gastroenterology Kobe Asahi HospitalKobe653-0801Japan Department of Radiology Osaka City University Medical SchoolOsaka545-8585Japan Department of Gastroenterology and Hepatology Kinki University School of MedicineOsaka-Sayama589-8511Japan Division of Molecular Medicine & Medical Genetics International Center for MedicalResearch and Treatment(ICMRT)Kobe University Graduate School of MedicineKobe650-0017Japan

We describe a 15-mm scirrhous hepatocellular carcinoma(HCC) in a 60-year-old man with B-type *** disclosed a 15-mm hypoechoic nodule in segment ***-enhanced US revealed heterogeneous,not diffuse,hypervascularity in the early phase and a defect in the Kupffer ***-enhanced computed tomography(CT) revealed a heterogeneous hypervascular nodule in the early phase and a low-density area in the late *** resonance imaging(MRI) revealed iso-to hypointensity at T1 and high intensity at T2-weighted ***-enhanced MRI also revealed a heterogeneous hypervascular nodule in the early phase and washout in the late ***-paramagnetic iron oxide-MRI revealed a hyperintense *** during hepatic arteriography and CT during arterial portography revealed heterogeneous hyperattenuation and a perfusion defect,*** on these imaging findings the nodule was diagnosed as a mixed well-differentiated and moderately-differentiated ***,the nodule was moderately-differentiated HCC characterized by typical cytological and structural atypia with dense ***,the nodule was positive for heterochromatin protein 1 and alpha-smooth muscle actin,and negative for cytokeratin *** the above findings,the nodule was diagnosed as scirrhous *** engaged in hepatology should exercise caution with suspected scirrhous HCC when imaging studies reveal atypical findings,as shown in our case on the basis of chronic liver disease.

关键词：原发性肝癌影像学表现非典型对比增强MRI 细胞角蛋白19 经肝动脉造影计算机断层扫描超顺磁性氧化铁

Analysis of aerodynamic and thermodynamic parameters on the grassy marshland surface of Tibetan Plateau

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Progress in Natural Science:Materials International 2002年第1期 38-42页

作者： TSUKAMOTO Osamu,ISHIKAWA Hirohiko,TAMAGAWA ichiro Faculty of Science Okayama University Okayama 700 Japan Disaster Prevention Research Institute Kyoto University Uji Kyoto 611 Japan Department of Civil Engineering Gifu University Gifu-shi 501-1193 Japan

The aerodynamic roughness z0m, the thermodynamic roughness Z0h and the excess resistance to heat transfer kB-1 are analyzed with the data obtained from Global Energy and Water Cycle Experiment (GEWEX) Asian Monsoon Experiment on Tibetan Plateau (GAME/Tibet) in the Intensive Observation Period (IOP), 1998. Some new concepts on the aerodynamic and thermodynamic parameters over the grassy marshland surface of the Tibetan Plateau are proposed.

关键词： Tibetan Plateau grassy marshland surface aerodynamic roughness thermodynamic roughness excess resistance to heat transfer.

Favorable and unfavorable amino acid residues in water-soluble and transmembrane proteins

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Journal of Biomedical Science and Engineering 2013年第1期6卷 36-44页

作者： Hiroshi Nakashima Ayano Yoshihara Kei-ichiro Kitamura Department of Clinical Laboratory Science Graduate Course of Medical Science and Technology School of Health Science Kanazawa University Kanazawa Japan

We analyzed the amino acid residues present in the water-soluble and transmembrane proteins of 6 thermophilic and 6 mesophilic species of the domains Archaea and Eubacteria, and characterized them as favorable or unfavorable. The characterization was performed by comparing the observed number of each amino acid residue to the expected number calculated from the percentage of nucleotides present in each gene. Amino acids that were more or less abundant than expected were considered as favorable or unfavorable, respectively. Comparisons of amino acid compositions indicated that the water-soluble proteins were rich in charged residues such as Glu, Asp, Lys, and His, whereas hydrophobic residues such as Trp, Phe, and Leu were abundant in transmembrane proteins. Interestingly, our results found that although the Trp residue was abundant in transmembrane proteins, it was not defined as favorable by our calculations, indicating that increased numbers of a particular amino acid does not necessary indicate it is a favorable residue. Amino acids with high G + C content such as Ala, Gly, and Pro were frequently observed as favorable in species with low G + C content. Comparatively, amino acids with low G + C content such as Phe, Tyr, Lys, Ile, and Met were frequently observed as favorable in species with high G + C content. These are the examples to increase the supply of amino acids than expected. Amino acids with neutral G + C content, i.e., Glu and Asp were favorable in water-soluble proteins from all species analyzed, and Cys was unfavorable both in water-soluble and transmembrane proteins. These results indicate that amino acid compositions are essentially determined by the nucleotide sequence of the genes, and the amino acid content is altered by a deviation from expectation.

关键词： Amino Acid Composition Nucleotide Composition Favorable and Unfavorable Residues Water-Soluble and Transmembrane Proteins Thermophilic and Mesophilic Species

Degradation of Aqueous 2,6-Dibromophenol Solution by In-Liquid Dielectric Barrier Microplasma

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World Journal of Engineering and Technology 2016年第3期4卷 423-432页

作者： Shin-ichiro Kojima Keiko Katayama-Hirayama Tetsuya Akitsu Department of Advanced Energy Engineering Science Kyushu University Kasuga Japan Interdisciplinary Graduate School of Medicine and Engineering University of Yamanashi Kofu Japan

Degradation of 2,6-dibromophenol (2,6-DBP) in the aqueous solution was studied using dielectric barrier discharge in micro-bubbles. Experimental comparison of working gas Ar, N2, O2, and air showed that oxygen and air plasma efficiently decomposed 2,6-DBP to bromide ion, and inorganic carbon. The molecular orbital model was applied in the analysis of the degradation in electrophilic, nucleophilic, and radical reactions.

关键词： 2 6-Dibromophenol Atmospheric Pressure Plasma Inductive Energy-Storage System

Assessment of Cervical Screw Trajectory Using 3-Dimensional Software Planning

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Open Journal of Modern Neurosurgery 2015年第1期5卷 6-11页

作者： Yu-ichiro Ohnishi Koichi Iwatsuki Toshiki Yoshimine Department of Neurosurgery Osaka University Medical School Suita Japan

Objective: It is important and helpful for surgeons to understand the correlation between spinal anatomy and screw trajectory before surgery. We aimed to assess a simple technique using 3D imaging software available on the hospital intranet for visual and quantitative feedback to prepare surgeons for an appropriate entry point and safe trajectory when placing cervical screws. Methods: A total of 59 cervical screws were inserted from C1 to T1 in 12 consecutive patients using this technique. First, a single CT optimal slice was selected from 3D CT images of the cervical spine to determine the intervals of bilateral entry points and lateral angle. Next, this 3D image was rotated to the lateral angle. Finally, bone was cut out on the entry point using subtractive manipulation, which removed the core of the pedicle or lateral mass. Screw trajectory was indicated, and surgeons could assess the correlation between surface landmarks, spinal anatomy, and screw trajectory. Posterior cervical fusion was performed using fluoroscopy. Postoperative outcomes and incidence of complications were retrospectively assessed. Results: One perforation (1.4%) was identified on postoperative CT images. No vascular injuries occurred. Differences in the intended entry point location and lateral angle of the screw from actual postoperative values were 1.49 ± 1.23 mm and 5.46。 ± 4.46。, respectively. Conclusions: A novel 3D CT imaging assessment underwent in cervical screw fixation. This technique is easily accessible on the hospital intranet and provides training in cervical screw placement for fellows. Surgeons can simulate screw placement and share surgical strategy.

关键词： Cervical Screw Trajectory 3D CT Planning Simulation Training

Depletion of Glial Cell Line-Derived Neurotrophic Factor by Disuse Muscle Atrophy Exacerbates the Degeneration of Alpha Motor Neurons in Caudal Regions Remote from the Spinal Cord Injury

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Neuroscience & Medicine 2014年第5期5卷 214-221页

作者： Yu-ichiro Ohnishi Koichi Iwatsuki Toshiki Yoshimine Department of Neurosurgery Osaka University Medical School Suita Japan

We have been previously reported that disuse muscle atrophy exacerbates both motor neuron (MN) degeneration in caudal regions remote from a spinal cord injury, and decrease in glial cell line-derived neurotrophic factor (GDNF) protein level in paralyzed muscle. In this study we found that disuse muscle atrophy exacerbated the decrease in GDNF protein level in the L4/5 spinal cord, which was not immunopositive for GDNF. Our results were consistent with the fact that in the lumbar spinal cord of rats with mid-thoracic contusion, GDNF expression was not detected, while expression of GDNF receptors (GFRα1 and RET) was. Our study showed that administration of exogenous recombinant GDNF into the atrophic muscle partially rescued α-MN degeneration in the L4/5 spinal cord. These results suggest that the depletion of GDNF protein by muscle atrophy exacerbates α-MN degeneration in caudal regions remote from the injury.

关键词： Disuse Muscle Atrophy Motor Neuron Degeneration Glial Cell Line-Derived Neurotrophic Factor

Effect of a Cosmetic Use with 2% Isostearyl-L-Ascorbic Acid Gel for Postinflammatory Hyperpigmentation and Postinflammatory Erythema in Acne Vulgaris

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Journal of Cosmetics, Dermatological Sciences and Applications 2020年第1期10卷 28-32页

作者： ichiro Kurokawa Masako Watanabe Kazuhito Hayashibe Department of Dermatology Meiwa Hospital Nishinomiya Hyogo Japan Kobayashi Skin Clinic Kobe Japan Hayashibe Skin Clinic Sanda Japan

Postinflammatory hyperpigmentation (PIH) and postinflammatory erythema (PIE) in acne vulgaris are important and refractory complications for patients with acne vulgaris. To clarify the effects of 2% isostearyl-L-ascorbic acid (ISAA) against PIH and PIE in acne vulgaris, a clinical pilot study with topical 2% ISAA gel was performed in 25 acne patients with PIH and PIE. Topical ISAA gel was applied on the whole face with PIH and PIE in acne vulgaris twice a day for 3 months. Regarding PIH and PIE, investigator’s global improvement rating (IGIR) was evaluated in 7-point scales according to the reduced area of PIH and PIE before and after the study. Remarkable improvement in PIH was observed in 7 patients (28.0%) and in PIE in 12 (48%) of the 25 patients. No adverse reactions were observed during the treatment. Topical ISAA application can be an alternative, non-invasive available treatment for PIH and PIE in acne vulgaris.

关键词： Acne Vitamin C Postinflammatory Hyperpigmentation Postinflammatory Erythema

Combination of Cyclamen persicum Mill. floral gene promoters and chimeric repressors for the modification of ornamental traits in Torenia fournieri Lind.

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Horticulture Research 2017年第1期4卷 324-334页

作者： ichiro Kasajima Norihiro Ohtsubo Katsutomo Sasaki Institute of Vegetable and Floriculture Science National Agriculture and Food Research Organization(NARO)Ibaraki305-8519Japan Department of Agriculture Iwate UniversityIwate 020-8550Japan Graduate School of Life and Environmental Sciences Kyoto Prefectural UniversityKyoto 606-8522Japan

Although chimeric repressors such as the Arabidopsis TCP3 repressor are known to have significant effects on flower morphology and color,their cellular-level effects on flower petals are not *** promoter sequences of the genes expressed in the flowers of cyclamen,a representative potted flower grown during the winter season,are also ***,we isolated eight promoters from cyclamen genes that are reportedly expressed in the *** promoters were then fused to four chimeric repressors and introduced into the model flower torenia to screen for effective combinations of promoters and repressors for flower *** expected,some of the constructs altered flower phenotypes upon *** further analyzed the effects of chimeric repressors at the cellular *** observed that complicated petal and leaf serrations were accompanied by excessive vascular *** in purple anthocyanin was inferred to result in bluish flowers,and imbalanced cell proliferation appeared to result in epinastic ***,the genetic constructs and phenotypic changes described in this report will benefit the future breeding and characterization of ornamental flowers.

关键词： traits flowers breeding