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Computed Tomography Evaluation of Tumor Response in Oncology in Togo

Journal of Cancer Therapy 2021年第12期12卷 695-707页

作者： Abdoulatif Amadou Pihou Gbande Ablavi Adani-Ifè Massaga Dagbe icael youaleu Lantam Sonhaye Lama Kedigoma Agoda-Koussema Komlanvi Adjenou Radiology and Medical Imaging Department Centre Hospitalier Régional Kara Kara Togo Radiology and Medical Imaging Department Centre Hospitalier Régional de Sokodé Sokodé Togo Department of Oncology Centre Hospitalier Universitaire Sylvanus Olympio Lomé Togo Radiology and Medical Imaging Department Centre Hospitalier Universitaire de Kara Kara Togo Radiology and Medical Imaging Department Centre Hospitalier Universitaire Sylvanus Olympio Lomé Togo

Cancer is common in our setting and represents a real public health concern in sub-Saharan Africa. This work aimed to assess the role of computed tomography in the follow-up of patients treated for cancer in Togo. This was a retrospective descriptive study carried out over a period of one year, on patients with cancer, treated in the medical oncology unit of CHU Sylvanus Olympio and having undergone at least two CT scans after cancer treatment. Computed tomography evaluation was performed according to the RECIST 1.1 guidelines. We had found 46 patients. The mean age of the patients was 54.22 years with a female predominance (sex ratio 1:2.5). Cancers mainly involved the urogenital system (60.8%) followed by the digestive system (28.3%). Carcinoma represented 93.5% of cases, mainly adenocarcinoma (45.7%). 74 target lesions were present at baseline, with 18.9% and 11.6% disappearing at the first and second assessments respectively. 36 non-target lesions were present at baseline, with 25% and 22.2% disappearing at the first and second assessments respectively. New lesions were found in the abdominal region in 54.5% of cases and in the thoracic region in 41.3% at the first and second assessments respectively. 58.7% of patients had a stable disease at the first assessment and 39.1% had progression at the second assessment. 50% of them had received chemotherapy in combination with surgery. Computed tomography using the RECIST 1.1 guidelines is a necessity in monitoring tumor extensions and in the follow-up of cancer patients.

关键词： Cancer Response Tumoral Computed Tomography RECIST 1.1 Togo

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