Objective:To investigate thein vitroandin vivoeffect of whole plant extracts ofPeristrophe bicalyculataonTrypanosoma brucei brucei-infected ***:The experiment wasdivided into two phases:In the first phase,the anti-try...
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Objective:To investigate thein vitroandin vivoeffect of whole plant extracts ofPeristrophe bicalyculataonTrypanosoma brucei brucei-infected ***:The experiment wasdivided into two phases:In the first phase,the anti-trypanosomal activity of the hot water,cold water,methanol and butanol extracts of the whole plant were determined by incubatingwithTrypanosoma brucei *** cold water extract was partially-purified and the anti-trypanosomal activity of the fractions *** the second phase,Trypanosoma brucei brucei-infected rats were treated with fraction 2c for nine *** cell volume(PCV),highdensity lipoprotein(HDL),low density lipoprotein(LDL),total cholesterol(TC),triacylglycerol(TAG),aspartate aminotransferase,alanine aminotransferases(ALT),alkaline phosphatase(ALP),total and direct bilirubin levels were determined at the end of the ***:Cold water extract immobilized 90%of the parasites after 60 min of incubation,and fraction 2ccompletely immobilized the parasites after 35 *** significantly increased PCV inTrypanosoma brucei brucei-infected *** TC,TAG,HDL and LDL levels of infected rats increasedsignificantly when rats were treated with the fraction,while elevated levels of total bilirubinand ALT also *** difference in urea,direct bilirubin and ALP was not significantwhen infected rats were compared to rats in other ***:The ability of the plantto ameliorate the infection-induced biochemical changes calls for detailed investigation of thepotentials of the plant for antitrypanosomiasis drug delivery.
Objective:To assess the proportion of caregivers of children and patients who received malaria prevention counseling from their healthcare provider at the time of outpatient malaria ***:This was a descriptive cross-se...
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Objective:To assess the proportion of caregivers of children and patients who received malaria prevention counseling from their healthcare provider at the time of outpatient malaria ***:This was a descriptive cross-sectional study involving 353 randomly selected adult patients and caregivers of children attending the general and paediatric outpatient clinics of a Nigerian *** interviewer-administered questionnaire was used to collect data on participants'sociodemographics and last malaria-episode *** square test and logistic regression analysis were used to determine factors associated with and predictors of receiving malaria-prevention counseling,***:The mean age of the respondents was(33.6±9.6)years;they were predominantly females(257,72.8%).Most had at least secondary-level education(304,86.1%);the family size was mostly 1-6 persons in 202(57.2%)*** were treated mostly by doctors 256(72.5%),but only 132(37.4%)received malaria prevention ***-level(x2=5.42,P=0.02),family size(Fisher's exact,P=0.01),place of treatment(Fisher's exact,P=0.0002),pretreatment malaria test(x2=9.48,P=0.002),who prescribed treatment(Fisher's exact P=0.001),consultation time(x2=22.09,P<0.001),and previous demand for malaria prevention counseling(x2=36.59,P<0.001)were associated with receiving malaria prevention ***,consultation time[Odd ratio(OR)=2.38,95%confidence interval(CI):1.28,4.40,P=0.006]and previous demand for malaria prevention counseling(OR=3.62,95%CI:2.15,6.10,P<0.001)were independent predictors of receiving ***:The proportion of respondents that received malaria prevention counseling was surprisingly *** offers opportunity for policy review towards improving the quality of outpatient malaria care through alternative strategies for giving malaria prevention information,especially in busy clinics where consultation time is constrained.
The use of computed tomography (CT) has increased over the past decades and has resulted in a concurrent increase in medical exposure to ionizing radiation. Several recent studies have examined the link between medica...
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The use of computed tomography (CT) has increased over the past decades and has resulted in a concurrent increase in medical exposure to ionizing radiation. Several recent studies have examined the link between medical radiation and the risk of cancer, especially in children. Results are presented in terms of the volumetric computed tomography dose index (CTDIvol) and dose length product (DLP) for head, chest and abdomen. The 75th percentile of adult CTDIvol for head, chest and abdomen are 85 mGy, 13.34 mGy and 13.29 mGy respectively and the corresponding DLP values 1437.47 mGy·cm, 417.49 and 656.02 mGy·cm. However, the paediatric head based on age group 0 - 1 yr, 1 - 5 yrs, 6 - 10 yrs and 11 - 15 years are 28.18 mGy, 32.12 mGy, 32.13 mGy and 28.20 mGy and corresponding DLP values 399.75 mGy·cm, 514.38 mGy·cm, 578.42 mGy·cm and 487.11 mGy·cm respectively and for paediatric abdomen from 1 - 5 years to 11 - 15 years are 3.98 mGy, 4.26 mGy and 5.92 mGy and the corresponding DLP 99.36 mGy·cm, 160.84 and 235.85 mGy·cm. The finding shows considerably high CTDIvol and DLP values for adult head comparable to the international standard thus optimization is required. Reduction in radiation doses for both adult and paediatric patients involve training of staff and optimize CT protocols.
Concrete is a major material used in the construction of buildings and structures in the *** and sand are the major ingredients of concrete but are non-renewable natural ***,the utilisation of palm oil clinker(POC),a ...
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Concrete is a major material used in the construction of buildings and structures in the *** and sand are the major ingredients of concrete but are non-renewable natural ***,the utilisation of palm oil clinker(POC),a solid waste generated from palm oil industry is proposed to replace natural aggregate in this research to reduce the demand for natural *** mix of ordinary concrete as control concrete;while four mix proportions of oil palm clinker concrete were obtained by replacing 25%,50%,75%,and 100%of gravel and sand of control concrete with coarse and fine oil palm clinker respectively by volume,with same cement content and water cement *** strength test was carried out of concretes with different percentages of oil palm clinker;whereas water absorption tests according to respective standard,were carried out to determine the durability properties of various *** on the results obtained,the study on the effect of percentage of clinker on strength and durability properties was *** to ACI classification of light weight concrete only the 100 percentage replacement can achieve the definition of light weight concrete since its density is less than 1,900 kg/m3 and strength larger than 17 *** the 25%replacement of the normal aggregate by the OPC will improve the strength and durability of the concrete.
In this study,we concluded the Hamiltonian equations on(M3,φ,ξ,η,g𝑔),being a *** introduce,some geometrical and physical results on the related mechanic systems have been discussed.
In this study,we concluded the Hamiltonian equations on(M3,φ,ξ,η,g𝑔),being a *** introduce,some geometrical and physical results on the related mechanic systems have been discussed.
A research was conducted to assess the effects of three different drying techniques, namely open sun drying (OSD), solar dryers (SD) and solar tent dryers (STD). Data on physical characteristics such as weight, ...
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A research was conducted to assess the effects of three different drying techniques, namely open sun drying (OSD), solar dryers (SD) and solar tent dryers (STD). Data on physical characteristics such as weight, total length and standard length were recorded and proximate composition of the fish sample Clarias gariepinus (Burchell, 1822) was carried out before, during and after drying to assess changes on physical characteristics and nutrient composition at different level. After drying, the samples were subjected to storage for eight weeks. The result obtained shows that there was no significant (P 〉 0.01) difference in the drying weight of the fish samples between the direct SD and the STD. However, for the total and standard length there was significant (P 〈 0.01) difference in the drying techniques, but no significant difference (P 〉 0.05) in the drying period. There was no significant (P 〉 0.05) difference on the physical parameters, storage period, proximate composition of both direct SD and STD and the drying period, respectively. Therefore, direct SD can be substituted with the STD without altering the quality of the product.
Although the distribution of cytomegalovirus (CMV) infection has a wide regional variation, it is more common in Africa and Asia with high prevalence approaching 100% in some communities. CMV is a frequent opportunist...
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Although the distribution of cytomegalovirus (CMV) infection has a wide regional variation, it is more common in Africa and Asia with high prevalence approaching 100% in some communities. CMV is a frequent opportunistic infection and major cause of morbidity and mortality among HIV patients with severe immunosuppression. It can be contracted from body fluid, including saliva, urine, blood, cervical secretions, and semen. CMV seropositivity is considered the best laboratory measure of past infection. We determined the prevalence of CMV and the risk factors associated with its acquisition in a population of HIV positive patients. Anti-CMV IgG seroprevalence was 100% among HIV infected subjects and 98.6% among controls. Having multiple sexual partners and traditional practices were identified as risk factors associated with risk of contracting CMV infection.
One hundred twenty-five endophytic microorganisms were isolated from the roots,stems,and leaves of four prominent rice cultivars growing in temperate *** potential to combat rice blast disease and promote plant growth...
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One hundred twenty-five endophytic microorganisms were isolated from the roots,stems,and leaves of four prominent rice cultivars growing in temperate *** potential to combat rice blast disease and promote plant growth was *** dual culture tests highlighted the strong antagonistic activity of five fungal(ranging from 89%–70%)and five bacterial(72%–61%)*** examination focused on volatile compounds produced by selected isolates to counter the blast *** these,the highest chitinase(13.76μg mL−1)and siderophore(56.64%),was exhibited by Aspergillus flavus,and the highest HCN production was shown by Stenotrophomonas maltophilia(36.15μM mL−1).In terms of growth promotion traits,Aspergillus flavus and Enterobacter cloacae excelled in activities viz,phosphorous solubilization,ammonia production,auxin and gibberellic acid production,and nitrogen *** Identity of these endophytes was confirmed through molecular analysis as Trichoderma afroharzianum,Trichoderma harzianum,Penicillium rubens,Aspergillus flavus,Stenotrophomonas rhizophila,Stenotrophomonas maltophilia,Bacillus cereus,Enterobacter cloacae,and Bacillus *** greenhouse conditions,the highest disease control was shown by isolate Bacillus licheniformis and *** with an inhibition of 79%,followed by ***(77%)and ***(73%).The overall results of this study showed that Bacillus licheniformis and Stenotrophomonas rhizophila have great potential to be used as bio-stimulant and biocontrol agents to manage rice blast disease.
In a retrospective study of 1224 transthoracic echocardiograms performed between January 2011 and December 2013, we evaluated the spectrum of congenital heart disease (CHD) diagnosed at a tertiary referral centre in M...
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In a retrospective study of 1224 transthoracic echocardiograms performed between January 2011 and December 2013, we evaluated the spectrum of congenital heart disease (CHD) diagnosed at a tertiary referral centre in Maiduguri, north-eastern Nigeria. Diagnosis of CHD was made in 88 (8.3%) subjects, comprising 23 (26.1%) adults and 65 (73.9%) aged less than 18 years. Forty six (52.3%) of those with CHD were females, while 42 (47.7%) were males. The frequencies of the CHD in decreasing order were: ventricular septal defect 23 (26.1%), tetralogy of Fallot (TOF) 14 (15.9%) and atrial septal defect (ASD) and atrioventricular septal defect (AVSD) were 11 (12.5%) each. One of the patients with AVSD had Ellis Van Creveldt syndrome. Six (6.8%) cases of patent ductus arteriosus (PDA) were diagnosed in those younger than 18 years, while all the 5 (5.7%) cases of Ebstein’s anomaly were diagnosed in adults. There were 6 (6.8%) cases of Eisenmenger syndrome involving three cases of AVSD, one case of ASD and two cases of Ebstein’s anomaly. Timely definitive cares for these patients are still lacking in Nigeria and many areas of sub-Saharan Africa. We recommend sensitization of all relevant clinicians to actively look for congenital heart defects. Pulse oximetry and postnatal echocardiographic new-born screening which were previously validated should be implemented at secondary and tertiary levels, and efforts should be made towards providing the needed care for patients with CHD.
Objective: To evaluate the effect of Zingiber officinale (ginger) and Hibiscus sabdariffa (roselle) as dietary supplements on serum biochemistry and some metabolites (urea and creatinine) in Clarias gariepinus (C. gar...
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Objective: To evaluate the effect of Zingiber officinale (ginger) and Hibiscus sabdariffa (roselle) as dietary supplements on serum biochemistry and some metabolites (urea and creatinine) in Clarias gariepinus (C. gariepinus). Methods: A total of 150 C. gariepinus juveniles [initial weight (35.41 ± 1.53) g] were randomly assigned to five test diets. Ginger and roselle were added to diets as additives at 2 g and 4 g respectively while control diet contained none of the substances. Blood samples were collected from treatment groups for biochemical analysis after 70 days feeding trial. Results: Significant changes (P 0.05) were seen in ginger treated fish. Conclusions: The present study revealed that ginger and roselle added to the diets as additives had no adverse effect on the examined serum biochemistry in C. gariepinus.
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