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Characterization of candidate factors associated with the metastasis and progression of high-grade serous ovarian cancer

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Chinese Medical Journal 2023年第24期136卷 2974-2982页

作者： Huiping Liu Ling Zhou Hongyan Cheng shang Wang Wenqing Luan e Cai Xue Ye Honglan Zhu Heng Cui Yi Li Xiaohong Chang Department of Obstetrics and Gynecology Peking University People’s HospitalBeijing 100044China Center of Gynecologic Oncology Peking University People’s HospitalBeijing 100044China

Background:High-grade serous ovarian cancer(HGsOC)is the biggest cause of gynecological cancer-related mortality because of its extremely metastatic *** study aimed to explore and evaluate the characteristics of candidate factors associated with the metastasis and progression of ***:Transcriptomic data of HGsOC patients’samples collected from primary tumors and matched omental metastatic tumors were obtained from three independent studies in the National Center for Biotechnology Information(NCBI)Gene expression Omnibus(GeO)*** expressed genes(DeGs)were selected to evaluate the effects on the prognosis and progression of ovarian cancer using data from The Cancer Genome Atlas(TCGA)*** genes’immune landscapes were estimated by the Tumor Immune estimation Resource(TIMeR)***,using 25 HGsOC patients'cancer tissues and 10 normal fallopian tube tissues,immunohistochemistry(IHC)was performed to quantify the expression levels of hub genes associated with International Federation of Gynecology and Obstetrics(FIGO)***:Fourteen DeGs,ADIPOQ,ALPK2,BARX1,CD37,CNR2,COL5A3,FABP4,FAP,GPR68,ITGBL1,MOXD1,PODNL1,sFRP2,and TRAF3IP3,were upregulated in metastatic tumors in every database while CADPs,GATA4,sTAR,and TsPAN8 were ***2,FAP,sFRP2,GATA4,sTAR,and TsPAN8 were selected as hub genes significantly associated with survival and *** hub genes were correlated with tumor microenvironment infiltration,especially cancer-associated fibroblasts and natural killer(NK)***,the expression of FAP and sFRP2 was positively correlated with the International Federation of Gynecology and Obstetrics(FIGO)stage,and their increased protein expression levels in metastatic samples compared with primary tumor samples and normal tissues were confirmed by IHC(P=0.0002 and P=0.0001,respectively).Conclusions:This study describes screening for DeGs in HGsOC primary tumors and matched metastasis tumors usi

关键词： High-grade serous ovarian cancer Metastasis Gene expression Omnibus Prognosis Recurrence Immune infiltration

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基于FLUX 2D的大型同步发电机在额定运行下定子绕组匝间短路故障特性研究

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中国电机工程学报 2013年第3期33卷 125-132,7页

作者：叶志军游佰强 J.Rosendahl s.T.Kulig 多特蒙德工业大学电机拖动与机电一体化研究所厦门大学信息科学与技术学院福建省厦门市361005

该文采用单一绕组分析和有限元分析相结合的方法,研究大型同步发电机在额定运行方式下定子绕组匝间短路故障特性。该方法同样适用于确定故障条件下的电流和转矩。对于内部故障情况的电磁瞬态仿真必须考虑到一些特殊措施,如单一绕组和电... 详细信息

该文采用单一绕组分析和有限元分析相结合的方法,研究大型同步发电机在额定运行方式下定子绕组匝间短路故障特性。该方法同样适用于确定故障条件下的电流和转矩。对于内部故障情况的电磁瞬态仿真必须考虑到一些特殊措施,如单一绕组和电网之间正确的连接对于模拟内部故障是相当关键的。以往的结果表明,在内部磁场非对称的情况下,基于等效电路的经典算法是不适用的。该文通过对汽轮发电机匝间短路故障进行系统的研究,表明:其短路电流、相电流、转矩和径向力与短路的位置及匝数紧密相关。在一些短路情况下,发电机将产生很大的局部电流,该局部电流对同步发电机的影响甚至超过外部故障。此外,很大的径向力作用在转子上可能对整个转轴产生极大的危害。

关键词：同步发电机定子绕组有限元法匝间短路

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Dielectric,ferroelectrics properties and impedance spectroscopy analysis of the[(Na_(0.535)K_(0.480))_(0.966)Li_(0.058)](Nb_(0.90)Ta_(0.10))O_(3)-based lead-free ceramics

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Journal of Advanced Dielectrics 2015年第1期5卷 50-56页

作者： M.saidi A.Chaouchi s.D'Astorg M.Rguiti C.Courtois Laboratoire de Chimie Appliquée et Génie Chimique de l'UniversitéMouloud Mammeri de Tizi-Ouzou Algérie Laboratoire des Matériau Céramiques et Procédés Associés—Universitéde Valenciennes et du Hainaut-Cambrésis Boulevard Charles de Gaull 59600 MaubeugeFrance University of Lille Nord de France F-59000 Lille France

Polycrystalline of[(Na_(0.535)K_(0.480))_(0.966)Li_(0.058)](Nb_(0.90)Ta_(0.10))O_(3)samples were prepared using the high-temperature solid-state reaction technique.X-ray diffraction(XRD)analysis indicates the formation of a single-phase with orthorhombic *** impedance plots were used as tool to analyze the electrical behavior of the sample as a function of frequency at different *** AC impedance studies revealed the presence of grain effect,from 425℃*** impedance analysis indicated non-Debye type dielectric *** Nyquist plot showed the negative temperature coefficient of resistance(NTCR)characteristic of *** AC conductivity results were used to correlate with the barrier hopping(CBH)model to evaluate the binding energy(W_(m)),the minimum hopping distance(R_(min)),the density of states at Fermi level(N(e_(f))),and the activation energy of the compound.

关键词： Lead-free piezo-ceramics dielectric properties AC impedance spectroscopy dielectric relaxation conductivity

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利用HHT方法对非平稳风力的时频分析

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振动与冲击 2011年第2期30卷 5-9,14页

作者：赵杨武岳曹曙阳段忠东 Yukio Tamura s. Ozono 哈尔滨工业大学土木工程学院哈尔滨150090 同济大学土木工程学院上海200092 Tokyo Polytechnic University Japan Department of Applied Physics Miyazaki University Miyazaki 889 -2192 Japan

非平稳信号的分析方法是信号分析领域中的一个重要问题。以风洞试验获得的非平稳风压信号和升力系数信号为研究对象,采用HHT方法对信号进行时频分析。HHT(Hilbert-Huang transform)方法可以获得有意义的瞬时频率,从而给出频率随时间变... 详细信息

非平稳信号的分析方法是信号分析领域中的一个重要问题。以风洞试验获得的非平稳风压信号和升力系数信号为研究对象,采用HHT方法对信号进行时频分析。HHT(Hilbert-Huang transform)方法可以获得有意义的瞬时频率,从而给出频率随时间变化的精确表达;信号最终被表示为时频平面上的能量分布,成为Hilbert谱;该方法适用于分析生活中普遍存在的大量频率随时间变化的非线性、非平稳信号,可将复杂的信号直接分离成从高频到低频的若干阶固有模态函数。分析结果虽然没有表现出明显的频谱分布特性,但与以往HHT分析结果提取的固有模态函数不同,如果对该试验获得的非平稳信号提取的固有模态是低频部分的残余信号,忽略其他高频信号,则风压时程和升力系数时程的残余信号曲线就可以分别回归为一个线性函数和一个正弦函数。这也说明,该非平稳信号的主成分仍然是由平稳信号组成的,可以用分析平稳信号的方法进行时程分析。

关键词：非平稳信号希尔伯特-黄经验模态分解法固有模态函数时程分析

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synthesis & Characterization of Organic-inorganic Hybrid Nano Composites Containing Non-linear Optical Dyes

Synthesis & Characterization of Organic-inorganic Hybrid Nan...

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The 12th Asian Pacific Confederation of Chemical engineering Congress

作者： Y.Aghilil M.Mohsenil e.Mohajerani s.Moradian A.Khosravi Laser Research Institute Shahid Beheshti UniversityTehranIran Department of Polymer eng. Amirkabir University of TechnologyP.O.Box.15875-4413TehranIran

A stable host-guest system has been prepared for improving the non-linear optical(NLO) effects as well as the mechanical and morphological properties of the polymeric host ***- perse Red 1(DR1)and a hybrid organic-ino... 详细信息

关键词： nano composites sol-gel non-linear optics poling second harmonic generation(sHG) dichroism birefringence

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Computational Nuclear Physics 1: Nuclear structure 1

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1991年

作者： M. Vallières H. Wu (auth.) Prof. K. Langanke Prof. Joachim A. Maruhn Prof. s. e. Koonin (eds.)

来源：畅想之星图书光盘版（南... 评论

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Unconditional Quantum Teleportation

Unconditional Quantum Teleportation

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CCAsT“量子纠缠态与量子信息”研讨会

作者： A. Furusawa J. L serensan s. L Braunstein C A. Fuchs H. J. Kimble e. s. Polzik

＜正＞ Quantum teleportation of optical coherent states was demonstrated experimentally using squeezed-state entanglement. The quantum nature of the achieved teieportation was verified by the experimentally determined fidelity = 0.58±0.02, which describes the match between input end output states. A fidelity greater than 0.5 is not possible for coherent states without the use of entanglement This is the first realization of unconditional quantum telePortation where every state entering the device is actually teleported.

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energy Aware Metaheuristic Optimization with Location Aided Routing Protocol for MANeT

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Computers, Materials & Continua 2022年第4期71卷 1567-1580页

作者： e.Ahila Devi K.C.Ramya K.sathesh Kumar sultan Ahmad seifedine Kadry Hyung Ju Park Byeong-Gwon Kang Department of Instrumentation and Control engineering St.Joseph’s College of EngineeringChennai600119India Department of electrical and electronics engineering Sri Krishna College of Engineering and TechnologyCoimbatore641008India school of Computing Kalasalingam Academy of Research and EducationKrishnankoil626128India Department of Computer science College of Computer Engineering and SciencesPrince Sattam Bin Abdulaziz UniversityAlkharj11942Saudi Arabia Department of Applied Data science Noroff University CollegeKristiansand4612Norway Department of ICT Convergence Soonchunhyang UniversityAsan31538Korea

A mobile ad hoc network(MANeT)involves a group of wireless mobile nodes which create an impermanent network with no central authority and *** nodes in the MANeT are highly mobile and it results in adequate network topology,link loss,and increase the re-initialization of the route discovery *** planning in MANeT is a multi-hop communication process due to the restricted transmission range of the *** aided routing(LAR)is one of the effective routing protocols in MANeT which suffers from the issue of high energy *** few research works have focused on resolving energy consumption problem in LAR,energy efficiency still remains a major design *** this aspect,this study introduces an energy aware metaheuristic optimization with LAR(eAMO-LAR)protocol for *** eAMO-LAR protocol makes use of manta ray foraging optimization algorithm(MRFO)to help the searching process for the individual solution to be passed to the LAR *** fitness value of the created solutions is determined next to pass the solutions to the objective *** MRFO algorithm is incorporated into the LAR protocol in the eAMO-LAR protocol to reduce the desired energy *** ensure the improved routing efficiency of the proposed eAMO-LAR protocol,a series of simulations take *** resultant experimental values pointed out the supreme outcome of the eAMO-LAR protocol over the recently compared *** resultant values demonstrated that the eAMO-LAR protocol has accomplished effectual results over the other existing techniques.

关键词： MANeT routing lar protocol energy efficiency mrfo algorithm metaheuristics

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Non-Traumatic Intracranial Heterotopic Ossification: A Case from Turkey

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Forensic Medicine and Anatomy Research 2016年第1期4卷 17-21页

作者： Mehmet Hanifi Kokacya Hasan Gökçe Zeynel Abidin Taş Dua sümeyra Demirkıran Muhammet Mustafa Arslan Department of Psychiatry Faculty of Medicine Mustafa Kemal University Hatay Turkey Department of Pathology Faculty of Medicine Inonü University Malatya Turkey Department of Pathology Faculty of Medicine Mustafa Kemal University Hatay Turkey Department of Forensic Medicine Faculty of Medicine Mustafa Kemal University Hatay Turkey

Heterotopic ossification (HO) is the abnormal, non-neoplastic presence of lamellar bone in soft tissue. The ectopic formation of lamellar bone in non-osseus tissues secondary to traumatic injuries of the spinal cord or the brain is defined as Neurogenic HO. The pathophysiology of HO is not clear. But several theories like overactive humoral mechanisms after fracture healing, imbalance of pro-osteoinductive and anti-osteoinductive mediators located on the soft tissues and gene mutations in such as bone morphogenetic proteins-4 (BMP-4) are proposed. Casualty factors leading to increased risk of HO include older age, blast mechanism of injury, location of injury and traumatic brain injury. The aim of this paper is to demonstrate a case of HO located in the brain without history of trauma or any other risk factors.

关键词： Heterotopic Ossification Autopsy Traumatic Brain Injury

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膀胱炎：细菌如何进入你的膀胱

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科学生活 2012年第12期 34-35页

作者： s.e.Gould 卓雅(译)

难缠的细菌总能摆脱人体的免疫系统，在你的膀胱里反复引发炎症。

关键词：膀胱炎细菌免疫系统炎症

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