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The Impact of Sleep-Wake Behaviour on Tennis Match Performance in Junior State Grade Tennis Players

Journal of Science in Sport and Exercise 2023年第2期5卷 156-166页

作者： Mitchell Turner Philipp Beranek ian c.dunican Travis cruickshank School of Medical and Health Sciences Edith Cowan University270 Joondalup DrivePerthWA 6027Australia centre for Sleep Science School of Human SciencesThe University of Western AustraliaPerthWA 6009Australia centre for Precision Health School of Medical and Health SciencesEdith Cowan UniversityPerthAustralia Perron Institute for Neurological and Translational Sciences PerthAustralia

Purpose To date,no study has investigated the extent to which sleep-wake behaviour(SWB)influences match performance in junior tennis *** study aimed to assess the influence of SWB for the week and night before on match performance,particularly match analytics and *** This study recruited 10 junior state grade tennis players who wore an actigraphy device and completed a sleep diary for the week before their match on two separate occasions throughout their competition *** wore a global positioning system device to track their movement during matches,and an experienced tennis coach recorded players'match *** This study showed that the sleep fragmentation index was significantly lower the week before matches in females who had won than those who had ***,the sleep fragmentation index was significantly lower the night before a given match than the week *** sleep fragmentation index and sleep latency significantly influenced match performance in junior tennis *** percentage of second serves points won differed between match wins and losses for male players,while winners and forced errors differed for female *** These findings provide a detailed profile of tennis match play in junior state grade *** individual differences,reduced restlessness the night before a match coincides with increased match performance.

关键词： Sleep fragmentation Tennis analytics Global positioning system Sleep quality Sleep duration

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Status and prospects for symmetric organic redox flow batteries

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Journal of Energy chemistry 2025年第1期100卷 125-143页

作者： Md Al Raihan c.Adam Dyker Department of chemistry University of New Brunswick

As environmental concerns from fossil fuel consumption intensify, large-scale energy storage becomes imperative for the integration of renewable sources like wind, hydro, and solar with the electrical *** flow batteries, particularly those employing organic molecules, are positioned as a key technology for this purpose. This review explores the growing field of symmetric organic redox flow batteries(ORFBs) within this context. Unlike traditional asymmetric designs based on unique active materials for each electrode, symmetric ORFBs involve a single bipolar species for both electrodes. This review highlights the benefits of a symmetric design, and categorizes five distinct classes of organic bipolar molecules used in both aqueous and non-aqueous solvents. By providing a comprehensive overview of their cell cycling and performance characteristics, the strengths and weaknesses of the diverse categories of bipolar molecules are highlighted for both solvent systems, as are opportunities for future development. This should guide new research directions and advance the development of practical symmetric ORFBs.

关键词： Redox flow battery Symmetric battery Organic battery Aqueous electrolyte Non-aqueous electrolyte

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Acquired sensorineural hearing loss,oxidative stress,and microRNAs

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Neural Regeneration Research 2025年第9期20卷 2513-2519页

作者： Desmond A.Nunez Ru c.Guo Division of Otolaryngology–Head&Neck Surgery Department of SurgeryFaculty of MedicineThe University of British ColumbiaVancouverBCCanada Division of Otolaryngology–Head&Neck Surgery Gordon&Leslie Diamond Health Care CentreVancouver General HospitalVancouverBCCanada Faculty of Medicine–The University of British columbia VancouverBCCanada

Hearing loss is the third leading cause of human ***-related hearing loss,one type of acquired sensorineural hearing loss,is largely responsible for this escalating global health ***-induced,ototoxic,and idiopathic sudden sensorineural are other less common types of acquired hearing *** etiology of these conditions is complex and multi-fa ctorial involving an interplay of genetic and environmental *** stress has recently been proposed as a likely linking cause in most types of acquired sensorineural hearing *** non-coding RNA sequences known as microRNAs(miRNAs)have increasingly been shown to play a role in cellular hypoxia and oxidative stress responses including promoting an apoptotic *** hair cell death is a central histopathological finding in sensorineural hearing *** these cells do not regenerate in humans,it underlies the irreversibility of human age-related hearing *** EMBASE,Ovid MEDLINE,Web of Science core collection,and *** databases over the period August 1,2018 to July 31,2023 were searched with"hearing loss,""hypoxamiRs,""hypoxia,""microRNAs,""ischemia,"and"oxidative stress"text words for English language primary study publications or registered clinical *** red clinical trials known to the senior author we re also assessed.A total of 222studies were thus *** excluding duplicates,editorials,retra ctions,secondary research studies,and non-English language articles,39 primary studies and clinical trials underwent full-text *** resulted in 11 animal,in vitro,and/or human subject journal articles and 8 registered clinical trial database entries which form the basis of this narrative *** miR-34a and miR-29b levels increase with age in *** miRNAs were demonstrated in human neuroblastoma and murine cochlear cell lines to target Sirtuin 1/peroxisome proliferato r-activated receptor gamma coactivator-1-alpha(SIRT1/P Gc-1α),SIRT

关键词： hearing loss hypoxia microRNAs oxidative stress sensorineural

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Multiple sclerosis is at a checkpoint: advancing the program

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Neural Regeneration Research 2025年第3期20卷 811-812页

作者： Brandon c.Smith Jessica L.Williams Department of Neurosciences Lerner Research InstituteCleveland ClinicClevelandOHUSA Department of Biological Geologicaland Environmental SciencesCleveland State UniversityClevelandOHUSA

Multiple sclerosis(MS) is a chronic inflammatory and demyelinating disease of the central nervous system(cNS). Patients with MS experience sensory and motor function loss due to myelin and/or axon damage perpetuated b... 详细信息

关键词： Hauser sclerosis damage

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What is left when anti-tumour necrosis factor therapy in inflammatory bowel diseases fails?

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World Journal of Gastroenterology 2014年第5期20卷 1248-1258页

作者： ian c Lawrance centre for Inflammatory Bowel Diseases Fremantle Hospital FremantleWA6059Australia Department of Medicine and Pharmacology University of Western Australia Fremantle Hospital FremantleWA6059Australia

The inflammatory bowel diseases (IBDs) are chronic incurable conditions that primarily present in young patients. Being incurable, the IBDs may be part of the patient’s life for many years and these conditions require therapies that will be effective over the long-term. Surgery in crohn’s disease does not cure the disease with endoscopic recurrent in up to 70% of patients 1 year post resection. This means that, the patient will require many years of medications and the goal of the treating physician is to induce and maintain long-term remission without side effects. The development of the anti-tumour necrosis factor alpha (TNFα) agents has been a magnificent clinical advance in IBD, but they are not always effective, with loss of response overtime and, at times, discontinuation is required secondary to side effects. So what options are available if of the anti-TNFα agents can no longer be used? This review aims to provide other options for the physician, to remind them of the older established medications like azathioprine/6-mercaptopurine and methotrexate, the less established medications like mycophenolate mofetil and tacrolimus as well as newer therapeutic options like the anti-integins, which block the trafficking of leukocytes into the intestinal mucosa. The location of the intestinal inflammation must also be considered, as topical therapeutic agents may also be worthwhile to consider in the long-term management of the more challenging IBD patient. The more options that are available the more likely the patient will be able to have tailored therapy to treat their disease and a better long-term outcome.

关键词： Inflammatory bowel disease Immunosuppression Anti-tumour necrosis factor agents Anti-integrin Long-term outcomes

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Application of the three-dimensional telegraph equation to cosmic-ray transport

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Research in Astronomy and Astrophysics 2016年第10期16卷 107-115页

作者： Robert c. Tautz ian Lerche Zentrum fur Astronomie und Astrophysik Technische Universitat Berlin HardenbergstraBe 36 D-10623 Berlin Germany Institut fur Geowissenschaften Naturwissenschaftliche Fakultat Ⅲ Martin-Luther-Universitat Halle D-06099 HalleGermany

An analytical solution to the three-dimensional telegraph equation is presented. This equation has recently received some attention but so far the treatment has been one-dimensional. By using the structural similarity to the Klein-Gordon equation, the telegraph equation can be solved in closed form. Illustrative examples are used to discuss the qualitative differences from the diffusion solution. A comparison with a numerical test-particle simulation reveals that some features of an intensity profile can be better explained using the telegraph approach.

关键词： plasmas -- turbulence -- magnetic field -- diffusion -- solar wind

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Preventing infective complications in inflammatory bowel disease

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World Journal of Gastroenterology 2014年第29期20卷 9691-9698页

作者： Justine Mill ian c Lawrance centre for inflammatory Bowel Diseases Fremantle Hospital Department of Medicine and Pharmacology University of Western AustraliaFremantle Hospital

Over the past decade there has been a dramatic change in the treatment of patients with crohn’s disease and ulcerative colitis, which comprise the inflammatory bowel diseases (IBD). This is due to the increasing use of immunosuppressives and in particular the biological agents, which are being used earlier in the course of disease, and for longer durations, as these therapies result in better clinical outcomes for patients. This, however, has the potential to increase the risk of opportunistic and serious infections in these patients, most of which are preventable. Much like the risk for potential malignancy resulting from the use of these therapies long-term, a balance needs to be struck between medication use to control the disease with minimization of the risk of an opportunistic infection. This outcome is achieved by the physician’s tailored use of justified therapies, and the patients’ education and actions to minimize infection risk. The purpose of this review is to explore the evidence and guidelines available to all physicians managing patients with IBD using immunomodulating agents and to aid in the prevention of opportunistic infections.

关键词： Infection complications Inflammatory bowel diseases Immunosuppression Anti-tumor necrosis factor agents

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Highway bridge seismic design:summary of FHWA/McEER project on seismic vulnerability of new highway construction

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Earthquake Engineering and Engineering Vibration 2002年第1期1卷 10-19页

作者： ian M.Friedland ian G.Buckle George c.Lee Applied Technology council 1300 Pennsylvania Ave NWSuite 700Washington D.C.20004USA Associate Director for Development Department of civil Engineering University of Nevada-RenoMail Stop 258RenoNevada89557USA Professor Multidisciplinary center for Earthquake Engineering Research.University at Buffalo.Red Jacket Quadrangle.Buffalo.New York 14260.USA Samuel P.Capen Professor

The Federal Highway Administration (FHWA) sponsored a large,multi-year project conducted by the Multidisciplinary center for Earthquake Engineering Research (McEER) titled'Seismic Vulnerability of New Highway construction'(McEER Project 112),which was completed in *** coordinated the work of many researchers,who performed studies on the seismic design and vulnerability analysis of highway bridges,tunnels,and retaining structures. Extensive research was conducted to provide revisions and improvements to current design and detailing approaches and national design specifications for highway *** program included both analytical and experimental studies,and addressed seismic hazard exposure and ground motion input for the *** system;foundation design and soil behavior: structural importance,analysis,and response:structural design issues and details;and structural design criteria.

关键词： Seismic design specifications bridges seismic hazard exposure ground motion input structural response analysis foundation design soil behavior

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Aberrant cytological localization of p16 and cDK4 in colorectal epithelia in the normal adenoma carcinoma sequence

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World Journal of Gastroenterology 2006年第39期12卷 6391-6396页

作者： PO Zhao Xin Mao ian c Talbot Department of Pathology Chinese PLA General Hospital Beijing 100853 China Academic Department of Pathology St. Mark's Hospital Cancer Research UK Colorectal Cancer Unit Harrow HA1 3UJ London United Kingdom

AIM： To study the correlation between the patterns of subcellular expression of p16 and cDK4 in colorectal epithelia in the normal-adenoma-carcinoma sequence.METHODS： Paraffin sections of 43 cases of normal colorectal epithelia and corresponding adenomas as well as carcinomas were analysed immunocytochemically for subcellular expression of p16 and cDK4 proteins.RESULTS： Most carcinomas showed more cytoplasmic overexpression for p16 and cDK4 than the adenomas from which they arised or the adjacent normal mucosa. Most normal or non-neoplastic epithelia showed more p16 and cDK4 expression in the nucleus than their adjacent adenomas and carcinomas. There was a significant difference between the subcellular expression pattern of p16 and cDK4 in normal-adenoma-carcinoma sequence epithelia （P 〈 0.001）. Neither p16 nor cDK4 subcellular patterns correlated with histological grade or Dukes＇ stage.cONcLUSION： Interaction of expression of p16 and cDK4 plays an important role in the Rb/p16 *** of p16 and cDK4 in the cytoplasm, as well as loss expression of p16 in the nucleusmighlc be important in the evolution of colorectal carcinoma from adenoma and, of adenoma from normal epitheiia.

关键词： colorectal neoplasm p16 cDK4 Immunocytochemistry

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Body image in paediatric burns: a review

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Burns & Trauma 2018年第2期6卷 93-98页

作者： ian c.c.King Department of Plastic and Reconstructive Surgery St George's HospitalTootingLondon SW170QTUK

Burn injuries in children can result in life-long disfigurement. As medical and surgical techniques of burn management improve survival prospects more than ever before, body image adjustment is increasingly a central consideration in the care of burn-injured individuals. An appreciation that both physiological and psychosocial processes underpin such injuries is key to understanding wound healing. Perceptions of idealized body images in Western society challenge children and their families as they grow up with and adapt to disfigurement from burns. Whilst many studies have examined the psychosocial recovery of adults with burn injuries, few have considered the impact on burn-injured children. This paper explores the models of body image and discusses the relevance of these to research and practice in understanding how to manage burns in children.

关键词： Burns Body image children Paediatric burns Wound healing

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