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Biotoxicity evaluation of zinc oxide nanoparticles on bacterial performance of activated sludge at COD,nitrogen,and phosphorus reduction

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Frontiers of Environmental Science & Engineering 2022年第2期16卷 51-62页

作者： Hasti Daraei Kimia Toolabian ian thompson Guanglei Qiu Environmental Health Engineering Research Center Kerman University of Medical SciencesKermanIran Department of Environmental Health Engineering Faculty of Public HealthKerman University of Medical SciencesKermanIran Faculty of Agriculture and natural resources Lorestan UniversityKhorramabadIran Department of Engineering Science University of OxfordParks RoadOxford OX13PJUK School of Environment and Energy South China University of TechnologyGuangzhou 510006China

The unique properties and growing usage of zinc oxide nanoparticles increase their release in municipal wastewater treatment ***,these nanoparticles,by interacting with microorganisms,can fail the suitable functioning of biological systems in treatment *** this reason,research into the toxicity of ZnO is *** the present study,the toxicity mechanism of ZnO-NPs towards microbial communities central to granular activated sludge(GAS)performance was assessed over 120-day *** results demonstrate that the biotoxicity of ZnO-NPs is dependent upon its dosage,exposure time,and the extent of reactive oxygen species(ROS)***,GAS performance and the extracellular polymeric substances(EPS)content were significantly reduced at 50 mg/L *** exposure led to decreases in the activity of ammonia monooxygenase(25.2%)and nitrate reductase(11.9%)*** Field emission scanning electron microscopy images confirmed that ZnO-NPs were able to disrupt the cell membrane integrity and lead to cell/bacterial death via intracellular ROS generation which was confirmed by the Confocal Laser Scanning Microscopy *** exposure to the NPs,the bacterial community composition shifted to one dominated by Gram-positive *** results of this study could help to develop environmental standards and regulations for NPs applications and emissions.

关键词： Granular sludge Biotoxicity Reactive oxygen species Extracellular polymeric substances

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英国文化遗产活动干预与城市儿童健康关联性循证研究

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城市发展研究 2020年第10期27卷 87-95页

作者：汤辉朱凯 ian thompson 华南农业大学林学与风景园林学院广东工业大学艺术与设计学院英国纽卡斯尔大学建筑规划与景观学院

随着医护模式的转变,"社会处方"这一投入小、收益大的服务模式在提升公共健康方面的重要性日益凸显。英国作为21世纪改善儿童健康状况的世界领导者之一,开拓性地探索了遗产、儿童健康与福祉之间的关系。以国民信托及英国遗产在英格兰泰... 详细信息

随着医护模式的转变,"社会处方"这一投入小、收益大的服务模式在提升公共健康方面的重要性日益凸显。英国作为21世纪改善儿童健康状况的世界领导者之一,开拓性地探索了遗产、儿童健康与福祉之间的关系。以国民信托及英国遗产在英格兰泰恩—威尔郡所管辖的14处遗产地作为基本空间单元,选择公立小学学生群体为研究对象,归纳影响儿童健康的潜在活动内容指标及量化方式,对14组变量构建多元线性回归模型,进行相关性分析与评价,循证文化遗产活动干预的各项指标对儿童健康提升的显著性和影响程度的强弱。旨在为我国文化遗产与健康的关联性提供依据。

关键词：公共健康英国遗产地活动儿童健康循证

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Prevalence of Isolated “Pre-Malignant” Lesions on Prostate Biopsy in a Racially Diverse Community Screened Cohort

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Open Journal of Urology 2015年第12期5卷 213-219页

作者： Michael A. Liss Donna Ankerst David Zapata Javier Hernandez Robin J. Leach ian M. thompson Department of Urology University of Texas Health Science Center San Antonio San Antonio USA Department of Epidemiology and Biostatistics University of Texas Health Science Center San Antonio San Antonio USA Department of Cellular and Structural Biology University of Texas Health Science Center San Antonio San Antonio USA Cancer Therapy and Research Center University of Texas Health Science Center San Antonio San Antonio USA

Objective: We investigated rates of prostate cancer (PCa), high-grade prostatic intraepithelial neoplaisa (HGPIN) and atypical small acinar proliferation (ASAP) in a multiethnic cohort. Methods: We evaluated prostate biopsy outcomes in men enrolled in the San Antonio Center of Biomarkers of Risk for prostate cancer (SABOR) prospective, observational study. PCa-free men underwent annual PSA testing over nearly 14 years with biopsies based on community standards. We investigated biopsy outcomes with a special interest in rates of cancer, HGPIN, and ASAP. Results: We identified 975 prostate biopsies in 801 subjects from 3/1/2001 to 1/9/2014. PCa, HGPIN, or ASAP was encountered in 28.8% (281/975), 10.1% (98/975), and 5.2% (51/975) of prostate biopsy specimens, respectively. The most significant risk factor for a PCa diagnosis was African American race (OR 5.0, 95% CI: 2.2 - 11.4, p < 0.001). HGPIN and ASAP occurred more commonly in association with PCa (both p < 0.001). We identified 57% (24/42) of men diagnosed with a “pre-malignant” lesion on prostate biopsy and had a subsequent biopsy. Of those only 8% (2/24) were diagnosed with prostate cancer (both Gleason 3 + 3) within 1 year of the initial biopsy. Conclusion: We note a 5-fold increased risk of PCa for African American men. The incidence of HGPIN and ASAP are consistent with previously reported incidence. If diagnosed in isolation, repeat biopsy within one year could be delayed or eliminated as it may not change prostate cancer outcomes.

关键词： Active Surveillance Ethnicity Prostate Biopsy Prostate Cancer Race

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临床限局性前列腺癌

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英国医学杂志中文版 2007年第2期10卷 94-99页

作者： Timothy J Wilt ian M thompson 郝秀原（译） Minneapolis VA Center for Chronic Disease Outcomes Research 1 Veterans Drive （111- 0） Minneapolis MN 55417 USA University of Texas Health Science Center San Antonio USA 不详

前列腺癌是英国男性最常见的癌症。2002年有32000例男性诊断为前列腺癌，超过10000例死于该病。随着血前列腺特异性抗原（PSA）检测的开展，前列腺癌的发病率也在升高，但疾病相关的死亡率在下降。本综述提供了该病的危险因素、预防、... 详细信息

前列腺癌是英国男性最常见的癌症。2002年有32000例男性诊断为前列腺癌，超过10000例死于该病。随着血前列腺特异性抗原（PSA）检测的开展，前列腺癌的发病率也在升高，但疾病相关的死亡率在下降。本综述提供了该病的危险因素、预防、检测、自然病程和治疗上的证据，重点探讨临床限局性前列腺癌，以指导全科医生的临床工作。

关键词：前列腺癌临床工作限局性前列腺特异性抗原疾病相关危险因素自然病程全科医生

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Correlation of PSA Density to Prostate Cancer Based on Prostate Volume by 3.0 T MRI

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Open Journal of Urology 2011年第3期1卷 28-36页

作者： Rulon L. Hardman Yuanyuan Liang Steve Ware Adam J. Jung Qi Peng Fadi El-Merhi Yumin Chen ian M. thompson Department of Radiology University of Texas Health Science

Purpose: Prostate specific antigen levels can be normalized by the prostate volume to give a prostate specific antigen density (PSAd). Magnetic resonance imaging (MRI) can more accurately determine prostate zonal anatomy and prostate volumes compared to transrectal ultrasound, and hence may lead to more accurate PSAd measurements. Methods: Imaging and pathology of men undergoing prostate MRI from April 2007 to May 2009 were reviewed in this retrospective study. 73 patients were included for analysis, of which 45 had prostate cancer and 28 did not have cancer. Total, transitional zone, and peripheral zone values were determined by ultrasound prolate ellipse, MRI prolate ellipse, and MRI segmentation methods. Results: The study population showed an average PSA of 6.3 ng/mL, with the control mean PSA (8.8 ng/mL) being greater than the cancer group (5.3 ng/mL). Transrectal ultrasound underestimated the prostate volume (mean 27.7 mL versus MRI volume of 38.3 mL, p ≤ 0.001). No difference was seen between cancer and control populations using PSAd. PSAd correctly categorized low (Gleason < 7) and high-grade cancers (Gleason ≥ 7) in patients with malignancy. Conclusion: Transrectal ultrasound underestimates prostate volumes and hence is inaccurate in calculating PSAd. MRI more accurately depicts PSAd, however PSAd is unable to differentiate between patients with cancer and benign disease such as BPH or prostatitis.

关键词： Magnetic Resonance Imaging Prostatic Neoplasm Prostate-Specific Antigen

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重塑生活场域:英国乡村景观遗产地活动策略研究及启示

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中国园林 2021年第10期37卷 42-47页

作者：汤辉冯思懿朱凯 [英]伊恩·汤普森华南农业大学林学与风景园林学院广州510642 广东工业大学艺术设计学院英国纽卡斯尔大学建筑、规划与景观学院

以乡村庄园为代表的英国乡村景观遗产保护有着悠久的实践历史,其近20年来借助系统而丰富的活动设置和灵活的空间利用,从过去静态的博物馆式保护模式向融入当前各阶层、各年龄段公众生活的可持续场所转变,代表着当前世界乡村景观遗产保... 详细信息

以乡村庄园为代表的英国乡村景观遗产保护有着悠久的实践历史,其近20年来借助系统而丰富的活动设置和灵活的空间利用,从过去静态的博物馆式保护模式向融入当前各阶层、各年龄段公众生活的可持续场所转变,代表着当前世界乡村景观遗产保护与发展的理论与实践方向。通过对英国英格兰地区36处乡村庄园遗产地的实地考察,结合以文献综述、调查访问和案例分析为主的研究方法,梳理英国乡村景观遗产保护理念转向注重活动、与公众健康与福祉相联系的发展历程,从组织机构、活动类型与活动保障探讨其活动安排策略,并结合中国乡村景观遗产实际总结出以“多元价值”为本、以“儿童活动”为基、以“协同资源”为纲、以“公众参与”为领的经验启示。

关键词：风景园林英国乡村景观遗产文化景观乡村庄园活动策略

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微生物靶向降解型环保金属加工液的研制

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工业微生物 2023年第4期53卷 47-49页

作者：靳永昌 Muhammad Irfan Arif 陆世忠高雨宋海燕 ian P.thompson 赵凯利南京科润工业介质股份有限公司江苏南京211100 牛津大学苏州高等研究中心江苏苏州215123 牛津大学工程科学系英国牛津OX13PJ

文章采集了不同地区的金属加工液废液,分离筛选出了其中的微生物进行培养,以测试不同微生物及其组合对废液化学需氧量(COD)的去除能力。具体通过选出COD去除率高的微生物或组合,测试其在常规金属加工液不同原料中的适应性。然后以微生... 详细信息

文章采集了不同地区的金属加工液废液,分离筛选出了其中的微生物进行培养,以测试不同微生物及其组合对废液化学需氧量(COD)的去除能力。具体通过选出COD去除率高的微生物或组合,测试其在常规金属加工液不同原料中的适应性。然后以微生物适应强的原料为基础,开发出环保型金属加工液产品。经测试发现新开发的金属加工液的加工性能和稳定性能均可满足应用需求。最后从已使用3个月的金属加工液槽液中取样,与经过优化的微生物进行组合性COD去除率测试,试验结果表明COD去除率可从初始的54%提升至79%。

关键词：金属加工液设计废液处理易生物降解

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Deep learning based classification of sheep behaviour from accelerometer data with imbalance

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Information Processing in Agriculture 2023年第3期10卷 377-390页

作者： Kirk E.Turner Andrew thompson ian Harris Mark Ferguson Ferdous Sohel Discipline of Information Technology Murdoch UniversityMurdochWA 6150Australia Centre for Crop and Food Innovation Food Futures InstituteMurdoch UniversityMurdochWA 6150Australia College of Science HealthEngineering and EducationMurdoch UniversityMurdochWA 6150Australia neXtgen Agri Saint MartinsChristchurch 8022New Zealand

Classification of sheep behaviour from a sequence of tri-axial accelerometer data has the potential to enhance sheep *** behaviour is inherently imbalanced(e.g.,more ruminating than walking)resulting in underperforming classification for the minority activities which hold *** works have not addressed class imbalance and use traditional machine learning techniques,e.g.,Random Forest(RF).We investigated Deep Learning(DL)models,namely,Long Short Term Memory(LSTM)and Bidirectional LSTM(BLSTM),appropriate for sequential data,from imbalanced *** data sets were collected in normal grazing conditions using jaw-mounted and earmounted *** to this study,alongside typical single classes,e.g.,walking,depending on the behaviours,data samples were labelled with compound classes,e.g.,walking_-*** number of steps a sheep performed in the observed 10 s time window was also recorded and incorporated in the *** designed several multi-class classification studies with imbalance being addressed using synthetic *** models achieved superior performance to traditional ML models,especially with augmented data(e.g.,4-Class+Steps:LSTM 88.0%,RF 82.5%).DL methods showed superior generalisability on unseen sheep(i.e.,F1-score:BLSTM 0.84,LSTM 0.83,RF 0.65).LSTM,BLSTM and RF achieved sub-millisecond average inference time,making them suitable for real-time *** results demonstrate the effectiveness of DL models for sheep behaviour classification in grazing *** results also demonstrate the DL techniques can generalise across different *** study presents a strong foundation of the development of such models for real-time animal monitoring.

关键词： Sheep behaviour classification Data synthesis Class imbalance Grazing sheep

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Comparison of inconclusive rates between suction rectal biopsy and open strip rectal biopsy in children of different age groups:a single-center retrospective study

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World Journal of Pediatric Surgery 2020年第1期3卷 6-11页

作者： Cedric ian Ng Liet Hing Roy Teng Liesel Porrett Richard thompson Paediatric Surgery Gold Coast University HospitalSouthportQueenslandAustralia

background Rectal biopsy for the diagnosis for Hirschsprung's disease(HD)can be performed in several *** rectal biopsy(SRB)is the most widely used method for neonates and younger infants while open strip biopsy(OSB)is reserved for older *** notions suggest that SRB should not be used in older infants due to perceived thicker fibrous tissue in their rectal walls leading to higher rates of inconclusive *** study aims to compare the inconclusive rates of both methods in children of different age *** A retrospective study were carried out with patients aged 13 years who underwent SRB or OSB during a 4-year period in a single *** biopsies were performed on patients with HD with previous endorectal pull-through surgeries *** outcomes were rates of inconclusive results for SRB and OSB overall and when divided into different age *** 79 biopsies(57 SRB and 22 OSB)were included in the study.12 biopsies(9 SRB and 3 OSB)were deemed *** was no significant difference in the rate of inconclusive results between patients underwent SRB and OSB overall(15.8%vs 13.6%,p=1.000).The same results were obtained when patients were divided into under one year and over one year groups or other different age groups(30.0%vs 33.3%,p=1.000).Conclusions Despite low biopsy numbers,our study suggests that SRB provides comparable rates of inconclusive results with OSB in children of all age groups.

关键词： younger walls thick

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δ^(18)O record and temperature change over the past 100 years in ice cores on the Tibetan Plateau

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Science China Earth Sciences 2006年第1期49卷 1-9页

作者： Lonnie thompson Byrd Polar Research Center the Ohio State UniviersityCohumbusOH 43210USBLaboratory of Environment and Process on Tibetan Plateau Institute of Tibetan Plateau Research Chinese Academy of Sciences Beijing 100085 China

The 213 m ice core from the Puruogangri Ice Field on the Tibetan Plateau facilitates the study of the regional temperature changes with its δ18O record of the past 100 years. Here we combine information from this core with that from the Dasuopu ice core (from the southern Tibetan Plateau), the Guliya ice core (from the northwestern Plateau) and the Dunde ice core (from the northeastern Plateau) to learn about the regional differences in temperature change across the Tibetan Plateau. Theδ18O changes vary with region on the Plateau, the variations being especially large between South and North and between East and West. Moreover, these four ice cores present increasing δ18O trends, indicating warming on the Tibetan Plateau over the past 100 years. A comparative study of Northern Hemisphere (NH) temperature changes, the δ18O-reflected temperature changes on the Plateau, and available meteorological records show consistent trends in overall warming during the past 100 years.

关键词： Tibetan Plateau, ice core, temperature.

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