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INTERNET OF CONNECTED SERVGOODS:CONSIDERATIONS,CONSEQUENCES AND CONCERNS

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Journal of Syst.ms Science and Syst.ms Engineering 2015年第2期24卷 130-167页

作者： james M.Tien College of Engineering University of Miami

In an earlier paper （Tien 2012）, the author augurs that, in contrast.to the first.and second indust.ial revolutions which respectively focused on the development and the mass production of goods, the next - or third - indust.ial revolution is focused on the integration of services and/or goods; it began in this second decade of the 21st.Century. The Third Indust.ial Revolution （TIR） is underpinned by the integration or mass cust.mization of services and/or goods. The benefits of real-time mass cust.mization cannot be over-st.ted as goods and services become indist.nguishable and are co-produced as ＂ServGoods＂, resulting in an overwhelming economic advantage to the indust.ialized countries where the consuming cust.mers are at the same time the co-producing producers. Adding sensors to these ServGoods and letting them connect or communicate among themselves or with other ServGoods can result in an Intemet of Things （i.e., connected ServGoods）. A number of considerations, consequences and concerns relating to such an Intemet of Connected ServGoods are discussed herein.

关键词： Goods services ServGoods sensors Big Data decision analytics adaptive services digital manufacturing value chain supply chain demand chain mass production mass cust.mization indust.ial revolution Intemet of Things

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低剂量电离辐射引起T细胞免疫反应增强及可能的机制

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国外医学（放射医学核医学分册） 1991年第6期15卷 257-259页

作者： Makinodan T james st.邓文张鸿来

本文描述了低剂量电离辐射引起T细胞免疫反应增强现象,分析了其可能的机制,包括在使信号转换、转录和翻译机构稳定化方面应激蛋白和前列腺素的参与,以及DNA修复效率提高、细胞死亡假说等.

关键词： T细胞剂量免疫反应电离辐射

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What is Faculty of 1000 Medicine？

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Clinical oncology and cancer researeh 2011年第3期8卷 185-189页

作者： Boyle Helen Droz Jean Pierre Saramaki Outi Visakorpi Tapio Linton Kate Catto james Georg st.ssi LeBeau Michelle Claude Bernard Lyon 1 University France France University of Tampere Finland Finland University of Sheffield UK UK University Hospital Zürich Switzerland Switzerland University of Chicago USA USA

Faculty of 1000 Medicine is a unique online service that helps you st.y informed of high impact articles and access the opinions of global leaders in medicine.

关键词：学院医药在线服务

Evaluating the biosignature potential of ammonium in Proterozoic red beds and implications for the search for life on Mars

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Earth and Planetary Physics 2024年第6期8卷 836-853页

作者： Eva E.st.eken Philip Fralick st.phen Hillier Anthony R.Prave School of Earth and Environmental Sciences University of St AndrewsSt AndrewsKY169TSUK Department of Geology Lakehead UniversityThunder BayON P7B 5E1Canada The james Hutton Inst.tute CraigiebucklerAberdeenAB158QHUK Department of Soil and Environment Swedish University of Agricultural Sciences(SLU)SE-75007 UppsalaSweden

Over the past.two decades,it has become increasingly apparent that early Mars may once have been warmer,wetter and more habitable for microbial life than it is today,which has spurred discussions about potential biosignatures that may be preserved in Martian *** impediment to this line of research is the pervasive oxidation of Mars’surface due to photochemical oxidants that have likely dest.oyed remnants of organic ***,we invest.gate whether nitrogen(N)transferred from biomass to phyllosilicate minerals during diagenesis can be preserved in oxidized *** invest.gate two sequences of terrest.ial Proterozoic red beds,namely the Sibley Group(1.4 Ga)in Canada and the st.er Group(1.2 Ga)in Scotland,and we find enrichments in authigenic N in the range of several tens of ppm in both *** highest.concentrations(ca.100 ppm on average)are found in the most.desiccated red beds of the st.er Group,concurrent with enrichments in potassium(K).We discuss similarities and differences between the two sets of rocks with regards to salinity,pH,biological productivity and K-metasomatism,and we conclude that the ideal mechanism for the preservation of biogenic N in red beds may be in-situ release of ammonium from microbial mats into the clay subst.ate,possibly facilitated by early diagenetic,biologically induced *** and smectite have been observed on Mars,and experiments suggest.that Martian waters contained moderate amounts of dissolved ***,it is conceivable that a similar K and N enrichment process could have occurred as to what we document for the Proterozoic,preserving evidence of life that may have survived to the modern day.

关键词： red beds biosignature Mars nitrogen ammonium clay minerals

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Compressing local atomic neighbourhood descriptors

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npj Computational Materials 2022年第1期8卷 1593-1605页

作者： james P.Darby james R.Kermode Gábor Csányi Engineering Dept University of CambridgeTrumpington StCambridgeCB21PZUK Warwick Centre for Predictive Modelling School of EngineeringUniversity of WarwickCoventryCV47ALUK

Many atomic descriptors are currently limited by their unfavourable scaling with the number of chemical elements S *** length of body-ordered descriptors,such as the SOAP power spectrum(3-body)and the(ACE)(multiple body-orders),scales as(NS)^(ν)whereν+1 is the body-order and N is the number of radial basis functions used in the density *** introduce two dist.nct approaches which can be used to overcome this scaling for the SOAP power ***,we show that the power spectrum is amenable to lossless compression with respect to both S and N,so that the descriptor length can be reduced from O(N^(2)S^(2))to O(NS).Secondly,we introduce a generalised SOAP kernel,where compression is achieved through the use of the total,element agnost.c density,in combination with radial *** ideas used in the generalised kernel are equally applicably to any other body-ordered descriptors and we demonst.ate this for the(ACSF).

关键词： SOAP scaling kernel

Social Computing Unhinged

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Journal of Social Computing 2020年第1期1卷 1-13页

作者： james Evans University of Chicago ChicagoIL 60637and Santa Fe InstituteSanta FeNM 87501USA.

Social computing is ubiquitous and intensifying in the 21st.*** used to reference computational augmentation of social interaction through collaborative filtering,social media,wikis,and crowdsourcing,here I propose to expand the concept to cover the complete dynamic interface between social interaction and computation,including computationally enhanced sociality and social science,socially enhanced computing and computer science,and their increasingly complex combination for mutual *** recommends that we reimagine Computational Social Science as Social Computing,not merely using computational tools to make sense of the contemporary explosion of social data,but also recognizing societies as emergent computers of more or less collective intelligence,innovation and *** further proposes we imagine a socially inspired computer science that takes these insights into account as we build machines not merely to subst.tute for human cognition,but radically complement *** leads to a vision of social computing as an extreme form of human computer interaction,whereby machines and persons recursively combine to augment one another in generating collective intelligence,enhanced knowledge,and other social goods unattainable without each *** the example of science and technology,I illust.ate how progress in each of these areas unleash advances in the others and the beneficial relationship between the technology and science of social computing,which reveals limits of sociality and computation,and st.mulates our imagination about how they can reach past.those limits together.

关键词： social computing complex syst.ms computer supported cooperative work computational social science artificial intelligence human computer interaction human-centered computing

st.m cell therapy for heart failure:Medical breakthrough,or dead end?

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World Journal of st.m Cells 2021年第4期13卷 236-259页

作者： Mathieu Rheault-Henry ian White Diya Grover Rony Atoui Northern Ontario School of Medicine Sudbury P3E 2C6OntarioCanada Ross University School of Medicine St.Michael BB11093Barbados Division of Cardiac Surgery Health Sciences NorthNorthern Ontario School of MedicineSudbury P3E 3Y9OntarioCanada

Heart failure continues to be one of the leading causes of morbidity and mortality *** infarction is the primary causative agent of chronic heart failure resulting in cardiomyocyte necrosis and the subsequent formation of fibrotic scar *** pharmacological and non-pharmacological therapies focus on managing symptoms of heart failure yet remain unable to reverse the underlying *** transplantation usually cannot be relied on,as there is a major discrepancy between the availability of donors and *** a result,heart failure carries a poor prognosis and high mortality *** the heart lacks significant endogenous regeneration potential,novel therapeutic approaches have incorporated the use of st.m cells as a vehicle to treat heart failure as they possess the ability to self-renew and differentiate into multiple cell lineages and *** review will discuss past.present,and future clinical trials,factors that influence st.m cell therapy outcomes as well as ethical and safety *** and clinical st.dies have shown a wide spectrum of outcomes when applying st.m cells to improve cardiac *** may reflect the infancy of clinical trials and the limited knowledge on the optimal cell type,dosing,route of administ.ation,patient parameters and other important variables that contribute to successful st.m cell ***,the field of st.m cell therapeutics continues to advance at an unprecedented *** remain cautiously optimist.c that st.m cells will play a role in heart failure management in years to come.

关键词： st.m cells Heart failure Myocardial infarction Regeneration Remodeling Ethical issues

Effect of Hind Leg Morphology on Performance of a Canine-inspired Quadrupedal Robot

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Journal of Bionic Engineering 2015年第3期12卷 339-351页

作者： james Andrew Smith Jamil Jivraj Ryerson University 350 Victoria St. Toronto ON Canada

Biomimetic leg designs often appear to be arbitrarily chosen. To make a more objective choice regarding biomimetic leg configuration for small canine-inspired robots, we compare one hind leg to the same leg arranged in a different orientation, and show that the less biomimetic leg provides better performance. This differently-oriented leg design, which we call ＂transverse-mirrored＂ was more efficient and fast.r, both in simulation and experiment even though both leg configurations used the same passive and active components, rest.angles, and monoartieular knee spring. In experiments the normal configuration had a maximum speed of 0.33 m·s^-1 and a specific resist.nce of 5.1. Conversely, the less biomimetic transverse-mirrored configuration had a maximum speed of 0.4 m·s^-1 and specific resist.nce of 3.9. Therefore the transverse-mirrored leg＇s best.performance yields a 21% increase in speed and 24% decrease in specific resist.nce when compared to the best.performance achieved in the normal biomimetic leg. The major underlying reason is that the knee spring engages more readily in the transverse-mirrored configuration, resulting in this fast.r and more efficient locomotion. The conclusion is that simply copying from nature does not lead to optimal performance and that insight into the role played by passive design components on natural locomotory dynamics is important.

关键词： biomimetic legged robot quadruped leg design walking legged locomotion

Population genetics and breeding syst.m of Tupist.a pingbianensis (Liliaceae),a naturally rare plant endemic to SW China

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Journal of Syst.matics and Evolution 2010年第1期48卷 47-57页

作者： Richard ian MILNE Division of Environmental and Evolutionary Biology School of BiologyUniversity of St.AndrewsSt.AndrewsFife KY16 9THUK

The levels and partitioning of genetic diversity and inbreeding depression were invest.gated in Tupist.a pingbianensis,a narrow endemic of southeast.Yunnan,China,characterized by a naturally fragmented dist.ibution due to extreme specialization on a rare habitat *** genetic diversity and patterns of genetic variation within and among 11 populations were analyzed using amplified fragment length polymorphism markers with 97 individuals across its whole geographical *** levels of genetic variation were revealed both at the species level(P 99 = 96.012%;H t = 0.302) and at the population level(P 99 = 51.41%;H s = 0.224).st.ong genetic differentiation among populations was also detected(F st.= 0.2961;θⅡ = 0.281),which corresponded to results reported for typical animal-pollinated,mixed selfing,and outcrossing plant *** result was consist.nt with mating patterns detected by our pollination *** indirect est.mate of gene flow based on θⅡ was low(N m = 0.64).Special habitat and its life hist.ry traits might play an important role in shaping the genetic diversity and the genetic st.ucture of this species.A pollination experiment also failed to detect significant inbreeding depression upon F 1 fruit set,seed weight,and germinate rate *** a naturally rare species,*** is not seriously genetically impoverished and likely to have adapted to tolerating a high level of inbreeding early in its hist.ry,we propose this species need only periodic monitoring to ensure their continued persist.nce,but not intervention to remain viable.

关键词： AFLP genetic diversity genetic st.ucture inbreeding depression naturally rare plants Tupist.a pingbianensis.