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Outcomes after arthroscopic repair of rotator cuff tears in the setting of mild to moderate glenohumeral osteoarthritis

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World Journal of Orthopedics 2022年第7期13卷 631-643页

作者： ian s hong Allison J Rao Tyler L CarlLee Joshua D Meade Daniel J Hurwit Gregory scarola David P Trofa shadley C schiffern Nady Hamid Patrick M Connor James E Fleischli Bryan Michael saltzman Department of Orthopedic surgery Atrium Health Musculoskeletal InstituteCharlotteNC 28207United States Department of sports Medicine Orthocarolina Research InstituteCharlotteNC 28207United States Department of Orthopedic surgery Columbia University Irving Medical CenterNew York CityNY 10032United States Department of Orthopaedic surgery Carolinas Medical CenterCharlotteNC 28207United States Department of Orthopedic surgery OrthoCarolina Sports Medicine CenterCharlotteNC 28207United States

BACKGROUND Rotator cuff pathology is a very common source of shoulder ***,osteoarthritis of the glenohumeral joint can cause shoulder pain and produce similar *** management can be indicated for both pathologies,however,outcomes data is limited when examining rotator cuff repair(RCR) in the setting of glenohumeral arthritis(GHOA).Thus,this study sought to determine outcomes for patients who undergo RCR in the setting of *** To evaluate if a relationship exists between outcomes of RCR in the setting of *** This was a retrospective analysis of patients who underwent arthroscopic rotator cuff repair with concurrent glenohumeral osteoarthritis between *** were stratified based on rotator cuff tear size and glenohumeral osteoarthritis *** were paired 1:1 with patients without glenohumeral *** included had a minimum two year *** of conversion to total shoulder arthroplasty,complication rates following initial surgery,and patient-reported outcome measures were *** A total of 142 patients were *** number of patients that required total shoulder arthroplasty within two years after index surgery was low.2/71(2.8%) patients with GHOA,and 1/71(1.4%) without *** rotator cuff repair,both groups showed favorable patientreported *** Patients with glenohumeral osteoarthritis who underwent arthroscopic rotator cuff repair showed comparable outcomes to patients without glenohumeral osteoarthritis.

关键词： Rotator cuff repair Rotator cuff tear Glenohumeral osteoarthritis shoulder Arthroscopic Outcomes

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structural basis for polyuridine tract recognition by sARs-CoV-2 Nsp15

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Protein & Cell 2024年第7期15卷 547-552页

作者： Fumiaki Ito Hanjing Yang Z.hong Zhou Xiaojiang s.Chen Molecular and Computational Biology Department of Biological SciencesUniversity of Southern CaliforniaLos AngelesCA 90089United States Department of Microbiology Immunology and Molecular GeneticsUniversity of CaliforniaLos AngelesCA 90095United States California Nanosystems Institute University of CaliforniaLos AngelesCA90095United States Genetic Molecular and Cellular Biology ProgramKeck School of MedicineUniversity of Southern CaliforniaLos AngelesCA 90089United States Norris Comprehensive Cancer Center University of Southern CaliforniaLos AngelesCA 90089United States Center of Excellence in NanoBiophysics University of Southern CaliforniaLos AngelesCA 90089United States

Dear Editor,Coronaviruses have evolved a wide array of tactics to evade host antiviral *** host cells detect invading foreign nucleic acids including viral genome and viral replication intermediates,they activate interferon(IFN)signaling via cytoplasmic pattern recognition receptors(Kang et al.,2002;Kato et al.,2006).Remarkable stealth activities exhibited by coronaviruses are facilitated by a series of non-structural proteins(Nsps),such as Nsp15(Deng and Baker,2018;Deng et al.,2019;Hackbart et al.,2020),which is a uridine-specific endoribonuclease that mediates evasion of host detection of viral double-stranded RNA(dsRNA)(Bhardwaj et al.,2004;Deng et al.,2017;Frazier et al.,2021;Ivanov et al.,2004).Nsp15 targets a polyuridine[poly(U)]tract on the coronavirus negative strand RNA(Hackbart et al.,2020).Nsp15 limits the abundance and length of poly(U)within the negative strand RNA 5ʹ-extension by trimming down the initially synthesized poly(U)lead sequence to the optimal length that can suppress dsRNA formation but still serves as a template for poly(A)tail of the positive strand genome of the coronaviruses(Hofmann and Brian,1991).

关键词： p15 interferon template

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Motor cortical circuit adaptations in parkinsonism

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Neural Regeneration Research 2024年第10期19卷 2107-2108页

作者： hong-Yuan Chu Department of Neurodegenerative science Van Andel Research InstituteGrand RapidsMIUSA Aligning science Across Parkinson’s(AsAP)Collaborative Research Network

Parkinson's disease is a chronic and progressive neurodegenerative disorder characterized by the loss of dopaminergic neurons in the substantia nigra pars compacta,which leads to the featured motor impairment of parki... 详细信息

关键词： parkin impairment rigidity

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Nutrient transport following water transfer through the world's largest water diversion channel

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Journal of Environmental sciences 2024年第1期135卷 703-714页

作者： Yuanhui Cheng hong Zhang Wei Yin state Key Laboratory of Environmental Aquatic Chemistry Research Center for Eco-Environmental SciencesChinese Academy of SciencesBeijing 100085 China Changjiang Water Resources Protection Institute Wuhan 430051China University of Chinese Academy of sciences Beijing 100049China

Nutrient levels in the artificial channel constructed for the Middle Route Project are significant indicators of water quality safety and aquatic ecological integrity for this large,interbasin ***,the distribution and transport of nutrients along the channel were poorly *** on a time-series dataset as well as mass balance and material flow analysis methods,the water and nutrient transport fluxes in the Middle Route of the south-to-North Water Diversion Project were identified in this *** results indicate that the nutrient concentrations varied considerably with time,but there was no significant difference among the 30 stations of the main *** temperature difference was the major factor in the large fluctuations of water quality indicators over *** nutrient loadings varied with the water volume outputs from the main channel to the waterreceiving *** deposition was an important source of nutrients in the main channel,accounting for 9.13%,20.6%,and 0.635%of the nitrogen,phosphorus,and sulfur input from the Danjiangkou Reservoir,*** 2021,a net accumulation of 988 tons of N,29 tons of P,and 2,540 tons of s,respectively,were present in the main *** increase of these external and internal nutrient loadings would cause water quality fluctuation and deterioration in some local sections of the main *** study quantified the spatial and temporal patterns of nutrient transport in the Middle Route and revealed the ecological effects on the aquatic environment,assisting authorities on the project to develop effective water conservation strategies.

关键词： Nutrient transport spatiotemporal patterns The Middle Route The south-to-North Diversion Project Hydro-ecological effects Water-receiving cities

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Equalizer Zero-Determinant strategy in Discounted Repeated stackelberg Asymmetric Game

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Journal of systems science & Complexity 2024年第1期37卷 184-203页

作者： CHENG Zhaoyang CHEN Guanpu hong Yiguang Key Laboratory of systems and Control Academy of Mathematics and Systems ScienceChinese Academy of SciencesBeijing 100190China school of Mathematical sciences University of Chinese Academy of SciencesBeijing 100049China school of Electrical Engineering and Computer science KTH Royal Institute of Technology10044 StockholmSweden. Department of Control science and Engineering Tongji UniversityShanghai 201804China shanghai Research Institute for Intelligent Autonomous systems Tongji UniversityShanghai 210201China

This paper focuses on the performance of equalizer zero-determinant(ZD)strategies in discounted repeated stackelberg asymmetric *** the leader-follower adversarial scenario,the strong stackelberg equilibrium(ssE)deriving from the opponents’best response(BR),is technically the optimal strategy for the ***,computing an ssE strategy may be difficult since it needs to solve a mixed-integer program and has exponential complexity in the number of *** this end,the authors propose an equalizer ZD strategy,which can unilaterally restrict the opponent’s expected *** authors first study the existence of an equalizer ZD strategy with one-to-one situations,and analyze an upper bound of its performance with the baseline ssE *** the authors turn to multi-player models,where there exists one player adopting an equalizer ZD *** authors give bounds of the weighted sum of opponents’s utilities,and compare it with the ssE ***,the authors give simulations on unmanned aerial vehicles(UAVs)and the moving target defense(MTD)to verify the effectiveness of the proposed approach.

关键词： Discounted repeated stackelberg asymmetric game equalizer zero-determinant strategy strong stackelberg equilibrium strategy

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Recent advances and future therapy development for Alzheimer’s disease and related disorders

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Neural Regeneration Research 2024年第9期19卷 1877-1878页

作者： Megan hong Gal Bitan Department of Neurology David Geffen School of MedicineUniversity of California Los AngelesLos AngelesCAUSA Department of Chemistry and Biochemistry University of California Los AngelesLos AngelesCAUSA Molecular Biology Institute University of California Los AngelesLos AngelesCAUSA Brain Research Institute University of CaliforniaLos AngelesCAUSA

Over 55 million people globally live with Alzheimer’s disease(AD)or related dementias(ADRD)and the number is expected to double every twenty *** i l recent l y,onl y symptomatic treatments were available to patients with AD,including acetylcholine esterase inhibitors,of which the last one,galantamine,was approved by the Us Food and Drug Administration(FDA)in 2001.

关键词： Alzheimer globally patients

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Carbon allocation in Picea jezoensis:Adaptation strategies of a non-treeline species at its upper elevation limit

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Forest Ecosystems 2024年第3期11卷 347-357页

作者： Renkai Dong Na Li Mai-He Li Yu Cong Haibo Du Decai Gao hong s.He Key Laboratory of Geographical Processes and Ecological security in Changbai Mountains Ministry of EducationSchool of Geographical SciencesNortheast Normal UniversityChangchun130024China school of Natural Resources University of MissouriColumbiaMO65211USA swiss Federal Institute for Forest Snow and Landscape Research WSL8903BirmensdorfSwitzerland Northeast Institute of Geography and Agricultural Ecology Chinese Academy of SciencesChangchun130102China school of Life science Hebei UniversityBaoding071002China

Understanding the physiological adaptations of non-treeline trees to environmental stress is important to understand future shifts in species composition and distribution of current treeline *** aim of the present study was to elucidate the mechanisms of the formation of the upper elevation limit of non-treeline tree species,Picea jezoensis,and the carbon allocation strategies of the species on Changbai *** employed the^(13)C in situ pulse labeling technique to trace the distribution of photosynthetically assimilated carbon in Picea jezoensis at different elevational positions(tree species at its upper elevation limit(TsAUE,1,700 m a.s.l.)under treeline ecotone;tree species at a lower elevation position(TsALE,1,400 m a.s.l.).We analyzed^(13)C and the non-structural carbohydrate(NsC)concentrations in various tissues following *** findings revealed a significant shift in carbon allocation in TsAUE compared to *** was a pronounced increase inδ^(13)C allocation to belowground components(roots,soil,soil respiration)in TsAUE compared to ***,the C flow rate within the plant-soil-atmosphere system was faster,and the C residence time in the plant was shorter in *** trends indicate enhanced C sink activity in belowground tissues in TsAUE,with newly assimilated C being preferentially directed there,suggesting a more conservative C allocation strategy by *** at higher elevations under harsher *** a strategy,prioritizing C storage in roots,likely aids in withstanding winter cold stress at the expense of aboveground growth during the growing season,leading to reduced growth of TsAUE compared to *** results of the present study shed light on the adaptive mechanisms governing the upper elevation limits of non-treeline trees,and enhances our understanding of how non-treeline species might respond to ongoing climate change.

关键词： ^(13)C pulse labeling Carbon distribution Non-structural carbohydrates(NsC) Non-treeline species sink activity stressful environments Upper elevation limit

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A special Editor’s Issue on Magnesium Matrix Composites

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Acta Metallurgica sinica(English Letters) 2024年第3期37卷 389-390页

作者： Xianhua Chen hong Yang College of Materials science and Engineering Chongqing UniversityChongqing 400045China National Engineering Research Center for Mg Alloys Chongqing UniversityChongqing 400045China

Magnesium(Mg)alloys offer distinct advantages as one of the lightest structural *** remarkable weight advantages,being 35%lighter than aluminum alloy and a striking 78%lighter than steel,make them a focal point for research in automotive and aerospace *** emphasis stems from the overarching goal of reducing energy costs and enhancing overall performance[1,2].

关键词： alloy steel alloys

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Parametric“non-nested”discriminants for multiplicities of univariate polynomials

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science China Mathematics 2024年第8期67卷 1911-1932页

作者： Hoon hong Jing Yang Department of Mathematics North Carolina State UniversityRaleighNC 27695USA sMs-HCIC-school of Mathematics and Physics Center for Applied Mathematics of GuangxiGuangxi Minzu UniversityNanning 530006China

We consider the problem of complex root classification,i.e.,finding the conditions on the coefficients of a univariate polynomial for all possible multiplicity structures on its complex *** is well known that such conditions can be written as conjunctions of several polynomial equalities and one inequality in the *** polynomials in the coefficients are called discriminants for *** is also known that discriminants can be obtained using repeated parametric greatest common *** resulting discriminants are usually nested determinants,i.e.,determinants of matrices whose entries are determinants,and so *** this paper,we give a new type of discriminant that is not based on repeated greatest common *** new discriminants are simpler in the sense that they are non-nested determinants and have smaller maximum degrees.

关键词： parametric polynomial complex roots discriminant multiplicity resultant

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Transient responses of double-curved sandwich two-layer shells resting on Kerr's foundations with laminated three-phase polymer/GNP/fiber surface and auxetic honeycomb core subjected to the blast load

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Defence Technology（防务技术） 2024年第5期35卷 222-247页

作者： Nguyen Thi Hai Van Thi hong Nguyen Researcher&Lecturer Faculty of Industrial EducationThe University of Danang-University of Technology and Education48 Cao ThangDanang550000Viet Nam Researcher&Lecturer Faculty of Mechanical EngineeringThuyloi University175 Tay SonDong DaHanoi100000Viet Nam

This work uses refined first-order shear theory to analyze the free vibration and transient responses of double-curved sandwich two-layer shells made of auxetic honeycomb core and laminated three-phase polymer/GNP/fiber surface subjected to the blast *** of the two layers that make up the double-curved shell structure is made up of an auxetic honeycomb core and two laminated sheets of three-phase polymer/GNP/*** exterior is supported by a Kerr elastic foundation with three *** key innovation of the proposed theory is that the transverse shear stresses are zero at two free surfaces of each *** contrast to previous first-order shear deformation theories,no shear correction factor is ***'s exact solution was used to treat the double-curved shell problem with a single title boundary,while the finite element technique and an eight-node quadrilateral were used to address the other boundary *** ensure the accuracy of these results,a thorough comparison technique is employed in conjunction with credible *** problem model's edge cases allow for this kind of *** study's findings may be used in the post-construction evaluation of military and civil works structures for their ability to sustain explosive *** addition,this is also an important basis for the calculation and design of shell structures made of smart materials when subjected to shock waves or explosive loads.

关键词： Blast load Two-layer shell Polymer/GNP/Fiber surface Auxetic honeycomb shear connectors

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