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Drought-responsive genes expressed predominantly in root tissues are enriched with homotypic cis-regulatory clusters in promoters of major cereal crops

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The Crop Journal 2017年第3期5卷 195-206页

作者： Muhammad Ramzan khan imran khan Zahra Ibrar Jens Léon Ali Ahmed Naz Institute of Crop Science and Resource Conservation(INRES) Department of Crop Genetics and BiotechnologyRheinische Friedrich-Wilhelms University of BonnGermany National Centre for Bioinformatics(NCB) Quaid-i-Azam UniversityIslamabadPakistan National Institute for Genomics and Advanced Biotechnology(NIGAB) National Agricultural Research CentrePark RoadIslamabadPakistan

The root appears to be the most relevant organ for breeding drought stress ***, our knowledge about temporal and spatial regulation of drought-associated genes in the root remains fragmented, especially in crop plants. We performed a meta-analysis of expression divergence of essential drought-inducible genes and analyzed their association with cis-elements in model crops and major cereal crops. Our analysis of42 selected drought-inducible genes revealed that these are expressed primarily in roots,followed by shoot, leaf, and inflorescence tissues, especially in wheat. Quantitative real-time RT-PCR analysis confirmed higher expression of TaDREB2 and TaAQP7 in roots,correlated with extensive rooting and drought-stress tolerance in wheat. A promoter scan up to 2 kb upstream of the translation start site using phylogenetic footprinting revealed708 transcription factor binding sites, including drought response elements(DREs), auxin response elements(Aux REs), MYCREs/MYBREs, ABAREs, and ERD1 in 19 selected ***, these elements were organized into clusters of overlapping transcription factor binding sites known as homotypic clusters(HCTs), which modulate drought physiology in plants. Taken together, these results revealed the expression preeminence of major drought-inducible genes in the root, suggesting its crucial role in drought adaptation. The occurrence of HCTs in drought-inducible genes highlights the putative evolutionary modifications of crop plants in developing drought adaptation. We propose that these DNA motifs can be used as molecular markers for breeding drought-resilient cultivars, particularly in the cereal crops.

关键词： Gene expression Promoter DREB cis-regulatory elements Phylogeny Drought adaptation

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Synergistic antibacterial effect of honey and Herba Ocimi Basilici against some bacterial pathogens

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Journal of Traditional Chinese Medicine 2013年第6期33卷 810-814页

作者： Ali Talha Khalil imran khan Kafeel Ahmad Yusra Ali khan Momin khan Muhammad Jaseem khan Department of Biotechnology Quaid-i-Azam University Centre of Biotechnology and Microbiology University of Peshawar Institute of Paramedical Sciences Khyber Medical University

OBJECTIVE： To evaluate the antibacterial activity of the combination of different honey brands and methanolic fraction of Herba Ocimi Basilici using agar well diffusion assay. METHODS： The antibacterial activity was deter- mined against thirteen pathogenic bacterial clini- cal isolates including six gram negative （Klebsiella pneumonia, Pseudomonas aeroginosa, Escherichia coli, Salmonella typhi, Salmonella typhimirium, Xanthomonas campestris） and six gram positive strains （Enterococcus faecalis faecalis, Bacillus subti- lis, Staphylococcus aureus, Clostridium perfringens type C, Clostridium perfringens type D, CIostridium chauvoei）. Agar well diffusion method was used while zones of inhibition were measured with verni- er scale. RESULTS： At higher concentration, all the honey brands showed good to significant activity. Thehighest activity was observed for Hamdard brand honey （27.60±0.40） against Enterococcus faecalis. CONCLUSION： These results revealed that combi- nations of plant extracts of Herba Ocimi Basilici with honey can be used for the development of potent and novel antibacterial agents.

关键词： Anti-infective agents Honey Gram-negative bacteria Gram-positive bacteria Well dif-fusion assay

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Antibacterial activity of honey in north-west Pakistan against select human pathogens

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Journal of Traditional Chinese Medicine 2014年第1期34卷 86-89页

作者： Ali Talha Khalil imran khan Yusra Ali khan Zabta khan Shinwari Kafeel Ahmad Jangrez khan Department of Biotechnology Quaid-i-Azam University Centre of Biotechnology and Microbiology University of Peshawar Department of Biochemistry Quaid-i-Azam University

OBJECTIVE:To investigate the antimicrobial activity of commercially available honey and raw honey samples in Khyber Pakhtunkhwa,Pakistan,against pathogenic bacterial ***:Well diffusion assays were performed to screen pure and diluted honey samples for antibacterial activity against six Gram-negative and six Gram-positive bacterial *** of inhibition were measured and compared with 10 mg ***:When honey samples were diluted to20%-70%,the honey samples showed no activity to mild antibacterial *** highest antibacterial activity was recorded when 90%and pure undiluted honey samples were tested and compared with a control Gentamycin disc(10 mg).CONCLUSION:Commercially processed honey and raw honey samples from north-west of Pakistan possess good antimicrobial potential.

关键词： Anti-bacterial agents Disk diffusion an-timicrobial tests Honey

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Perceptual quality assessment of panoramic stitched contents for immersive applications:a prospective survey

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Virtual Reality & Intelligent Hardware 2022年第3期4卷 223-246页

作者： Hayat ULLAH Sitara AFZAL imran Ullah khan Department of Computer Science Kansas State UniversityManhattanKS 66506USA Department of Software Sejong UniversitySeoul 143-747Republic of Korea

The recent advancements in the field of Virtual Reality(VR)and Augmented Reality(AR)have a substantial impact on modern day technology by digitizing each and everything related to human life and open the doors to the next generation Software Technology(Soft Tech).VR and AR technology provide astonishing immersive contents with the help of high quality stitched panoramic contents and 360°imagery that widely used in the education,gaming,entertainment,and production *** immersive quality of VR and AR contents are greatly dependent on the perceptual quality of panoramic or 360°images,in fact a minor visual distortion can significantly degrade the overall ***,to ensure the quality of constructed panoramic contents for VR and AR applications,numerous Stitched Image Quality Assessment(SIQA)methods have been proposed to assess the quality of panoramic contents before using in VR and *** this survey,we provide a detailed overview of the SIQA literature and exclusively focus on objective SIQA methods presented till *** better understanding,the objective SIQA methods are classified into two classes namely Full-Reference SIQA and No-Reference SIQA *** class is further categorized into traditional and deep learning-based methods and examined their performance for SIQA ***,we shortlist the publicly available benchmark SIQA datasets and evaluation metrices used for quality assessment of panoramic *** last,we highlight the current challenges in this area based on the existing SIQA methods and suggest future research directions that need to be target for further improvement in SIQA domain.

关键词： Virtual reality Augmented reality Panoramic image Immersive contents Stitched image quality assessment Deep learning Convolutional neural networks

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A simple and facile iodination method of didechlorotiacumicin B and aromatic compounds

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Science China Chemistry 2021年第10期64卷 1736-1742页

作者： Haibo Zhang Liping Zhang imran khan Guangtao Zhang Yiguang Zhu Changsheng Zhang Key Laboratory of Tropical Marine Bio-resources and Ecology Guangdong Key Laboratory of Marine Materia MedicaRNAM Center for Marine MicrobiologySouth China Sea Institute of OceanologyChinese Academy of SciencesGuangzhou 510301China Sanya Institute of Oceanology SCSIOYazhou Scientific BaySanya 572000China Southern Marine Science and Engineering Guangdong Laboratory(Guangzhou) Guangzhou 511458China University of Chinese Academy of Sciences Beijing 100049China

Tiacumicin B(also known as fidaxomicin or difimicin)is a marketed 18-membered macrolide antibiotic for the treatment of Clostridium difficile *** B is structurally characterized with two chlorine atoms substituted on the aromatic ring,which is installed by the halogenase Tia *** the study on halide compatibility of Tia M,a facile and nonenzymatic iodination method of didechlorotiacumicin B was discovered,requiring Na I,acid and air for iodination at room *** method was also amenable to other 9 aromatic substrates with electron-rich sites for iodination.

关键词： iodination tiacumicin metal-free facile chemistry

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Chemical composition, mechanism of antibacterial action and antioxidant activity of leaf essential oil of Forsythia koreana deciduous shrub

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Asian Pacific Journal of Tropical Medicine 2015年第9期8卷 682-688页

作者： Xiao-Nan Yang imran khan Sun Chul Kang Department of Biotechnology College of Engineering Daegu University Kyungsan

Objective: To identify the chemical constituents of leaf essential oil of Forsythia koreana(F. koreana) and evaluate its ef ects on bacterial strains. Methods: The essential oil of leaf of F. koreana was extracted by using hydrodistillation process and the volatile components investigated with the help of gas chromatography coupled with mass spectrometry. The antibacterial study was carried out with the help of agar disc dif usion method, MIC, MBC and viable count. The mode of action was determined with help of potassium ion l ux, cellular material release and scanning electron microscopy. The antioxidant activity was determined with the help of 2, 3-diphenyl-2-picrylhydrazyl method, nitric oxide scavenging activity and superoxide anion radical scavenging assay. Results: Total ten compounds were identii ed as trans-phytol(42.73%), cis-3-hexenol(12.95%), 毬-linalool(10.68%), trans-2-hexenal(8.86%), trans-2-hexenol(8.86%), myrcenol(3.86%), 4-vinylphenyl acetate(3.86%),(4Z)-4,6-heptadien-1-ol(3.18%), lemonol(2.73%) and benzeneacetaldehyde(2.27%) by gas chromatography coupled with mass spectrometry. The antibacterial study was demonstrated that leaf essential oil of F. koreana act against foodborne and other pathogenic bacteria. The mode of action revealed that this essential oil acted on the cytoplasmic membrane, resulting in loss of integrity and increased permeability. In addition, leaf essential oil of F. koreana was shown to be rich in linalool, which contributes to improved antioxidant activity. Conclusions: These results show that leaf essential oil of F. koreana has great potential as a natural food preservative, antibacterial and antioxidant agent.

关键词： Antibacterial activity Antioxidant activity Cell material released Essential oil GC-MS Potassium ion flux

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Proportional Fairness-Based Power Allocation Algorithm for Downlink NOMA 5G Wireless Networks

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Computers, Materials & Continua 2020年第11期65卷 1571-1590页

作者： Jianzhong Li Dexiang Mei Dong Deng imran khan Peerapong Uthansakul School of Finance Chongqing Technology and Business UniversityChongqingChina Department of Electrical Engineering University of Engineering and TechnologyPeshawarPakistan School of Telecommunication Engineering Suranaree University of TechnologyNakhon RatchasimaThailand

Non-orthogonal multiple access(NOMA)is one of the key 5G technology which can improve spectrum efficiency and increase the number of user connections by utilizing the resources in a non-orthogonal *** allows multiple terminals to share the same resource unit at the same *** receiver usually needs to configure successive interference cancellation(SIC).The receiver eliminates co-channel interference(CCI)between users and it can significantly improve the system *** order to meet the demands of users and improve fairness among them,this paper proposes a new power allocation *** objective is to maximize user fairness by deploying the least fairness in multiplexed ***,the objective function obtained is non-convex which is converted into convex form by utilizing the optimal Karush-Kuhn-Tucker(KKT)*** results show that the proposed power allocation scheme gives better performance than the existing schemes which indicates the effectiveness of the proposed scheme.

关键词： 5G NOMA user fairness resource optimization multiple access scheme

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Leveraging Augmented Reality,Semantic-Segmentation,and VANETs for Enhanced Driver’s Safety Assistance

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Computers, Materials & Continua 2024年第1期78卷 1443-1460页

作者： Sitara Afzal imran Ullah khan Irfan Mehmood Jong Weon Lee Mixed Reality and Interaction Lab Department of SoftwareSejong UniversitySeoul05006Korea Faculty of Engineering and Digital Technologies School of Computer ScienceAI and ElectronicsUniversity of BradfordBradfordUK

Overtaking is a crucial maneuver in road transportation that requires a clear view of the road ***,limited visibility of ahead vehicles can often make it challenging for drivers to assess the safety of overtaking maneuvers,leading to accidents and *** this paper,we consider atrous convolution,a powerful tool for explicitly adjusting the field-of-view of a filter as well as controlling the resolution of feature responses generated by Deep Convolutional Neural Networks in the context of semantic image *** article explores the potential of seeing-through vehicles as a solution to enhance overtaking ***-through vehicles leverage advanced technologies such as cameras,sensors,and displays to provide drivers with a real-time view of the vehicle ahead,including the areas hidden from their direct line of *** address the problems of safe passing and occlusion by huge vehicles,we designed a see-through vehicle system in this study,we employed a windshield display in the back car together with cameras in both *** server within the back car was used to segment the car,and the segmented portion of the car displayed the video from the front *** see-through system improves the driver’s field of vision and helps him change lanes,cross a large car that is blocking their view,and safely overtake other *** network was trained and tested on the Cityscape dataset using semantic *** transparent technique will instruct the driver on the concealed traffic situation that the front vehicle has *** our findings,we have achieved 97.1% *** article also discusses the challenges and opportunities of implementing see-through vehicles in real-world scenarios,including technical,regulatory,and user acceptance factors.

关键词： Overtaking safety augmented reality VANET V2V deep learning

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Acceleration of solar wind particles due to inertial Alfvén waves

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Communications in Theoretical Physics 2024年第6期76卷 137-141页

作者： Kiran Batool imran A khan M Shamir Abdul Kabir S Ayaz Theoretical Physics Department National Centre for PhysicsIslamabad 44000Pakistan Department of Space Sciences Institute of Space TechnologyIslamabad 44000Pakistan Space and Astrophysics Research Lab(SARL) National Center of GIS and Space Applications(NCGSA)Islamabad 44000Pakistan Salam Chair Department of PhysicsGC University LahoreKatchery RoadLahorePunjab 54000Pakistan Department of Space Science and CSPAR University of Alabama in HuntsvilleHuntsvilleAL 35899United States of America

Gaining an understanding of the effects and dynamics of the solar wind is crucial for the study of space weather,Earth's magnetosphere,spacecraft protection,the dynamics of the Solar System,and various other *** show that Alfvén waves effectively transfer energy to resonant *** study demonstrates how inertial Alfvén waves deliver their energy to resonant plasma particles in different solar environments under certain *** analysis shows that inertial Alfvén waves experience more rapid damping with increasing parallel wavenumber,ambient magnetic field strength,and particle number density,coupled with a decrease in *** rate of energy transfer to resonant particles intensifies with higher temperatures and reduced parallel wavenumber and particle number *** with higher initial velocities actively participate in Landau damping,especially in regions with a stronger ambient magnetic field.

关键词： solar wind inertial Alfven waves resonant particles

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The relationship between energy consumption, economic growth and carbon dioxide emissions in Pakistan

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Financial Innovation 2020年第1期6卷 56-68页

作者： Muhammad Kamran khan Muhammad imran khan Muhammad Rehan School of Economics Northeast Normal UniversityChangchunJilinChina

Developing countries are facing the problem of environmental *** degradation is caused by the use of non-renewable energy consumptions for economic growth but the consequences of environmental degradation cannot be *** primary purpose of this study is to investigate the nexus between energy consumption,economic growth and CO_(2) emission in Pakistan by using annual time series data from 1965 to *** estimated results of ARDL indicate that energy consumption and economic growth increase the CO_(2) emissions in Pakistan both in short run and long *** on the estimated results it is recommended that policy maker in Pakistan should adopt and promote such renewable energy sources that will help to meet the increased demand for energy by replacing old traditional energy sources such as coal,gas,and *** energy sources are reusable that can reduce the CO_(2) emissions and also ensure sustainable economic development of Pakistan.

关键词： Energy consumption Economic growth CO_(2)emissions ARDL

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