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叉车用安全装置的开发

中国安全生产科学技术 2015年第3期11卷 53-58页

作者：吕健池田博康冈部康平劳动安全卫生综合研究所

以机械设备为起因的工伤事故中,叉车事故比较常见。首先介绍了日本国内叉车事故的分类统计数据,从硬件设备方面,概述了叉车减灾的主要措施,针对驾驶员在行驶中将肢体伸出驾驶仓外时易发生冲撞或挤压事故的情况,提出了基于光幕及激光扫... 详细信息

以机械设备为起因的工伤事故中,叉车事故比较常见。首先介绍了日本国内叉车事故的分类统计数据,从硬件设备方面,概述了叉车减灾的主要措施,针对驾驶员在行驶中将肢体伸出驾驶仓外时易发生冲撞或挤压事故的情况,提出了基于光幕及激光扫描器的驾驶员肢体伸出仓外的监控方法。然后根据叉车的不同刹车性能指标,探讨了如何设定检测领域大小的问题。对蓄电池式1.5t叉车进行的实验表明,在检测系统能直接控制刹车的情况下,我们提出的方法是行之有效的。

关键词：叉车减灾安全装置激光扫描器光幕着座传感器肢体伸出监测

Effects of Cr and Cr/Mn Combined Additions on Semi-Solid Microstructures of Al-Mg-Si Alloys Produced by D-SSF Process

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Journal of Materials Science & Technology 2008年第1期24卷 21-24页

作者： Witthaya Eidhed hiroyasu Tezuka Tatsuo Sato Faculty of Engineering King Mongkut's Institute of Technology North Bangkok Thailand Department of Metallurgy and Ceramic Sciences Tokyo Institute of Technology Japan

The effects of Cr and Cr/Mn combined additions on the semi-solid microstructure of wrought Al-Mg-Si alloys are *** the Cr-added alloy,the Al-7Cr compound is formed with homogeneously distributed in theα-Al matrix after *** of the Al-7Cr andα-Al-（12）Mn3-Si-2 dispersiod particles are found in the homogenized microstructure of the Cr/Mn-added *** the semi-solid microstructures,the smallestα-Al grains are obtained in the 60% cold-rolled *** prolonged holding time,theα-Al grain size of the Cr/Mn-added alloy is smaller than that of the Cr-added *** deformation by cold-rolling accelerates spheroidization of theα-Al *** D-SSF process is found to be useful to modify the microstructures of both the Cr-added and Cr/Mn-added Al-Mg-Si alloys.

关键词： D-SSF process Semi-solid processing Thixoforming AI-Mg-Si alloy

Synthesis of Mesoporous, Nanocrystalline Lanthanum Phosphate in the Presence of Citric Acid and Stearic Acid

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Journal of Rare Earths 2007年第6期25卷 684-691页

作者： Li-Ngee Ho hiroyasu Nishiguchi Katsutoshi Nagaoka Yusaku Takita Department of Applied Chemistry Oita University Dannoharu 700 Oita 870-1192 Japan

Lanthanum phosphate was prepared in the presence of citric acid and stearic acid under methanolic conditions at pH 4.5 and pH 7, respectively. The samples obtained were intensively characterized using X-ray diffraction, nitrogen adsorption-desorption isotherm study, transmission electron microscopy （TEM）, thermal gravimetric and differential thermal analysis, and Fourier transform infrared （FTIR） analysis . The as-synthesized samples prepared at pH 4.5 showed lamellar mesostruroned form with high crystallinity. Results showed that the pore size and pore volume changed when the materials were prepared under different pH conditions. Morphology of the samples was observed by using TEM, which showed that the samples possessed relatively small particles closely packed together. The as-synthesized samples were investigated using FTIR, and the mesopore formation mechanism was discussed.

关键词： mesoporous lanthanum phosphate citric acid stearic acid nanocrystalline rare earths

Abemaciclib-induced lung damage leading to discontinuation in brain metastases from breast cancer: A case report

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World Journal of Clinical Cases 2023年第35期11卷 8425-8430页

作者： hiroyasu Yamashiro Nao Morii Department of Breast Surgery Tenri HospitalNaraTenri 632-8552Japan

BACKGROUND This case report addresses the dearth of effective therapeutic interventions for central nervous system metastases in patients with HER2-negative breast *** presents a unique case of a woman with estrogen receptor-positive,HER2-negative breast cancer who developed brain *** report highlights her initial favorable response to abemaciclib and letrozole therapy prior to the discon-tinuation due to drug-induced lung damage(DILD).CASE SUMMARY In this comprehensive case summary,we present the clinical course of a woman in her 60s,who 11 years following primary breast cancer surgery,was diagnosed with multiple brain *** a third-line systemic therapy,she underwent treatment with abemaciclib and *** treatment approach yielded a near-partial response in her metastatic brain ***,abemaciclib adminis-tration ceased due to the emergence of DILD,as confirmed by a computed tomography *** DILD improved after 1 mo of *** ongoing therapeutic efforts,the patient’s condition progressively deteriorated,ultimately resulting in death due to progression of the brain *** This case underscores the challenge of managing adverse events in responsive brain metastasis patients,given the scarcity of therapeutic options.

关键词： Breast cancer HER2 negative Brain metastasis Abemaciclib Drug-induced interstitial lung damage Case report

Chemoprevention of obesity-related liver carcinogenesis by using pharmaceutical and nutraceutical agents

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World Journal of Gastroenterology 2016年第1期22卷 394-406页

作者： hiroyasu Sakai Yohei Shirakami Masahito Shimizu Department of Gastroenterology/Internal Medicine Gifu University Graduate School of Medicine

Obesity and its related metabolic disorders are serious health problems worldwide,and lead to various healthrelated complications,including *** human cancers,hepatocellular carcinoma(HCC)is one of the most common malignancies affected by ***,obesity and its related disorders might be a key target for the prevention of ***,new research indicates that the molecular abnormalities associated with obesity,including insulin resistance/hyperinsulinemia,chronic inflammation,adipokine imbalance,and oxidative stress,are possible molecular mechanisms underlying the pathogenesis of obesityrelated *** tea catechins and branched-chain amino acids,both of which are classified as nutraceutical agents,have been reported to prevent obesity-related HCC development by improving metabolic *** administration of acyclic retinoid,a pharmaceutical agent,reduced the incidence of HCC in obese and diabetic mice,and was also associated with improvements in insulin resistance and chronic *** this article,we review the detailed molecular mechanisms that link obesity to the development of HCC in obese *** also summarize recent evidence from experimental and clinical studies using either nutraceutical or pharmaceutical agents,and suggest that nutraceutical and pharmaceutical approaches targeting metabolic abnormalities might be a promising strategy to prevent the development of obesity-related HCC.

关键词： Hepatocellular carcinoma Obesity Greentea catechins Branched-chain amino acids Acyclicretinoid

Dispersoid Formation and Recrystallization Behavior in an Al-Mg-Si-Mn Alloy

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Journal of Materials Science & Technology 2010年第3期26卷 237-243页

作者： Rong Hu Tomo Ogura hiroyasu Tezuka Tatsuo Sato Qing Liu Department of Materials-Science and Engineering Tsinghua University Beijing 100084 China Department of Metallurgy and Ceramics Science Tokyo Institute of Technology Tokyo Japan

The nucleation and precipitation of Mn-containing dispersoids in an Al-Mg-Si-Mn alloy （6082） have been studied by optical microscopy,EPMA （electron probe microanalysis） and TEM （transmission electron microscopy）.The influence of Mn-containing dispersoids on the recrystallization behavior was also *** size and distribution of dispersoids were strongly affected by both the homogenization process and the alloying element distribution formed in the direct chill cast *** Mn-containing dispersoids were observed to nucleate preferentially on the β-Mg 2 Si phase and to be aligned along the 〈100〉 direction of the *** cold deformation,the morphology of dispersoids greatly influences the recrystallization and grain growth behavior in the annealing process.

关键词： Mn-containing dispersoids Homogenization Recrystallization Grain refinement

Noninvasive assessment of liver fibrosis in patients with chronic hepatitis B

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World Journal of Gastroenterology 2014年第34期20卷 12031-12038页

作者： Masaru Enomoto hiroyasu Morikawa Akihiro Tamori Norifumi Kawada Department of Hepatology Osaka City University Graduate School of MedicineOsaka 5458585Japan

Infection with hepatitis B virus is an important healthproblem worldwide:it affects more than 350 millionpeople and is a leading cause of liver-related morbidity,accounting for 1 million deaths *** fibrosis is a consequence of the accumulation of extracellular matrix components in the *** accurate diagnosis of liver fibrosis is essential for the management of chronic liver *** biopsy has been considered the gold standard for diagnosing disease,grading necroinflammatory activity,and staging ***,liver biopsy is unsuitable for repeated evaluations because it is invasive and can cause major complications,including *** noninvasive evaluations have been introduced for the assessment of liver fibrosis:serum biomarkers,combined indices or scores,and imaging techniques including transient elastography,acoustic radiation force impulse,real-time tissue elastography,and magnetic resonance ***,we review the recent progress of noninvasive assessment of liver fibrosis in patients with chronic hepatitis *** noninvasive evaluations for liver fibrosis have been validated first in patients with chronic hepatitis C,and later in those with chronic hepatitis *** establishment of a noninvasive assessment of liver fibrosis is urgently needed to aid in the management of this leading cause of chronic liver disease.

关键词： Acoustic radiation force impulse Biomarkers Biopsy Elastography Fibrosis Hepatitis B Noninvasive evaluations

Water Resource Development in the Quaternary Ryukyu Limestone Regions of Japan:Application of the GIS to the Site Selection of Underground Dams

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Acta Geologica Sinica(English Edition) 2001年第3期75卷 254-259页

作者： Kaijun JIANG hiroyasu FURUKAWA Yuji ONOYAMA Testuro ESAKI Underground Dam Research Group Showa-chika Kogyo Inc. Fukuoka Japan 815-0082Underground Dam Research Group Showa-chika Kogyo Inc. Fukuoka Japan 815-0082Underground Dam Research Group Showa-chika Kogyo Inc. Fukuoka Japan 815-0082Institute of Environmental Systems Kyushu University Fukuoka Japan 812-8581

Based on the natural and social conditions as well as hydrogeological characteristics of the Ryukyu limestone, a major aquifer in the Ryukyu Islands, a conception of underground dam, was proposed in the early 1970s in order to develop ground water resources in the Quaternary Ryukyu limestone regions of Japan. The practice of nearly thirty years has shown that the underground dam is an environment-friendly and effective way for developing ground water in these regions.

关键词： underground dam limestone Quaternary GIS ground water

A new numerical simulation model for high pressure squeezing moulding

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China Foundry 2011年第1期8卷 25-29页

作者： Li Hua Wu Junjiao Huang Tianyou Makino hiroyasu Department of Mechanical Engineering Tsinghua University Beijing 100084 China SINTOKOGIO Ltd. Toyokawa Aichi Pref 4430021 Japan

High pressure squeeze is the most popular moulding process applied in modern moulding *** of the unique characters of moulding sand and nonlinearity of squeezing process,the mechanical model is of key importance for computer ***-Prager/Cap is a typical soil mechanical theory model and it was used to simulate the squeezing process in this study,while ABAQUS software is used to simulate dynamic stress/strain evolution during the *** simulation agrees well with the experimental *** conclude that Drucker-Prager/Cap is an appropriate model for the squeezing compaction of moulding sand,and that the associated nonlinearity can be solved well with ABAQUS software.

关键词： high pressure squeeze Drucker-Prager/Cap ABAQUS numerical simulation green sand moulding