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An Exploration of Deep-Learning Based Phenotypic Analysis to Detect Spike Regions in Field Conditions for UK Bread Wheat

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Plant Phenomics 2019年第1期1卷 162-178页

作者： Tahani Alkhudaydi Daniel Reynolds Simon Griffiths Ji Zhou Beatriz de la iglesia University of East Anglia Norwich Research ParkNorwich NR47TJUK University of Tabuk Faculty of Computers&ITTabuk 71491Saudi Arabia Earlham Institute Norwich Research ParkNorwich NR47UZUK John Innes Centre Norwich Research ParkNorwich NR47UHUK Plant Phenomics Research Center China-UK Plant Phenomics Research CentreNanjing Agricultural UniversityNanjing 210095China

Wheat is one of the major crops in the world,with a global demand expected to reach 850 million tons by 2050 that is clearly outpacing current *** continual pressure to sustain wheat yield due to the world’s growing population under fluctuating climate conditions requires breeders to increase yield and yield stability across *** are working to integrate deep learning into field-based phenotypic analysis to assist breeders in this *** have utilised wheat images collected by distributed CropQuant phenotyping workstations deployed for multiyear field experiments of UK bread wheat *** on these image series,we have developed a deep-learning based analysis pipeline to segment spike regions from complicated *** a first step towards robust measurement of key yield traits in the field,we present a promising approach that employ Fully Convolutional Network(FCN)to performsemantic segmentation of images to segment wheat spike *** also demonstrate the benefits of transfer learning through the use of parameters obtained from other image *** found that the FCN architecture had achieved a Mean classification Accuracy(MA)>82%on validation data and>76%on test data and Mean Intersection over Union value(MIoU)>73%on validation data and and>64%on test *** this phenomics research,we trust our attempt is likely to form a sound foundation for extracting key yield-related traits such as spikes per unit area and spikelet number per spike,which can be used to assist yield-focused wheat breeding objectives in near future.

关键词： Wheat breeding crops

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Synthesis and Catalytic Consequences of Metal Encapsulated Zeolites in Hydrogen Management

Synthesis and Catalytic Consequences of Metal Encapsulated Z...

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第十四届全国青年催化学术会议

作者：吴志杰 Enrique iglesia 重质油国家重点实验室 CNPC催化重点实验室中国石油大学(北京) Department of Chemical and Biomolecular Engineering University of California at Berkeley

＜正＞The report involves synthesis of metal clusters or oxides encapsulated zeolites and elucidation of their catalytic consequences. The encapsulation of metal or metal oxide clusters within pores of zeolites is an ... 详细信息

关键词： Zeolite Encapsulation Hydrogen Catalyst.

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Accuracy of endoscopic ultrasound-guided tissue acquisition in the evaluation of lymph nodes enlargement in the absence of on-site pathologist

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World Journal of Gastroenterology 2017年第31期23卷 5755-5763页

作者： Yung Ka Chin Julio iglesia.-Garcia Daniel de la iglesia.Jose Larino-Noia Ihab Abdulkader-Nallib Hector Lázare Susana Rebolledo Olmedo J Enrique Dominguez-Munoz Department of Gastroenterology and Hepatology University Hospital of Santiago de Compostela Health Research Institute of Santiago de Compostela (IDIS) University Hospital of Santiago de Compostela Department of Pathology University Hospital of Santiago de Compostela

To evaluate factors that influence the diagnostic accuracy of endoscopic ultrasound (EUS)-guided tissue acquisition for lymph node enlargement in the absence of an on-site pathologist. METHODSA retrospective analysis of patients who underwent EUS-guided tissue acquisition for the pathological diagnosis of lymph node enlargement between April 2012 and June 2015 is reported. Tissue acquisition was performed with both cytology and biopsy needles of different calibers. The variables evaluated were lymph node location and size, number of passes and type of needle used. Final diagnosis was based on surgical histopathology or, in non-operated cases, on EUS-guided tissue acquisition and imaging assessment with a minimum clinical follow-up of 6 mo. RESULTSDuring the study period, 168 lymph nodes with a median size of 20.3 mm (range 12.5-27) were sampled from 152 patients. Ninety lymph nodes (53.6%) were located at mediastinum, and 105 (62.5%) were acquired with biopsy needles. The final diagnosis was benign/reactive origin in 87 cases (51.8%), malignant in 65 cases (38.7%), and lymphoma in 16 cases (9.5%). The sensitivity, specificity, positive predictive value and negative predictive value for the detection of malignancy were 74.1%, 100%, 100% and 80.6%, respectively. The overall accuracy was 87.5% (95%CI: 81.7-91.7). No variables were independently associated with a correct final diagnosis according to the multivariate analysis. CONCLUSIONEUS-guided tissue acquisition is a highly accurate technique for assessing lymph node enlargement. None of the variables evaluated were associated with diagnostic accuracy.

关键词： Lymph node Endoscopic ultrasound Fine-needle aspiration Fine-needle biopsy Accuracy

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基于艺术治疗方法的护理干预在边缘型人格障碍患者中的应用

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International Journal of Nursing Sciences 2024年第2期11卷 205-213页

作者： Ana Morales-Alonso Angela iglesia.-de-la-iglesia.Miriam Alonso-Maza Dr.Rodríguez Lafora Hospital(Hospital Dr.Rodríguez Lafora) MadridSpain Department of Nursing and Stomatology University Rey Juan CarlosAlcorconMadridSpain

目的ZentangleR艺术治疗方法被应用于心理健康相关领域,尚未在边缘型人格障碍患者得到验证。本研究分析边缘型人格障碍患者接受ZentangleR艺术治疗方法的练习体验。方法采用现象学解释方法,对患者进行半结构化访谈。患者均已在西班牙某... 详细信息

目的ZentangleR艺术治疗方法被应用于心理健康相关领域,尚未在边缘型人格障碍患者得到验证。本研究分析边缘型人格障碍患者接受ZentangleR艺术治疗方法的练习体验。方法采用现象学解释方法,对患者进行半结构化访谈。患者均已在西班牙某医院的人格障碍治疗室接受了每个月1次,共6次ZentangleR艺术治疗。本研究中共访谈了15例患者。Smith、Flowers和Larkin方法用于资料分析中的评估。结果根据研究结果,共提炼出3个类别的主题:有耕耘即有收获(参与者报告了注意力、放松、人际关系、与环境互动方面的改善,以及接受和改变的积极体验);众擎易举(患者认可在团体中感觉更好,并建立了相互联系;他们也描述了团体环境对个人行为的影响);画出自己的轨迹(通过绘画方式提供了自我表达和自我认识的媒介,通过情感表达提升了幸福感,提高了创造力,增强了自信心)。结论通过练习ZentangleR,患者可以作出灵活性和适应性等行为反应,通过焦虑管理、冲动控制改善情绪健康,学习应对问题,提高自尊或注意力。心理健康护理在边缘型人格的综合治疗及协同多样化补充性干预措施中发挥着积极作用。

关键词：艺术治疗边缘型人格障碍心理健康护理 Zentangle®

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Effect of Oxygen Coverage on Methane Activation Pathways on Supported Platinum Clusters

Effect of Oxygen Coverage on Methane Activation Pathways on ...

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第十一届全国青年催化学术会议

作者：李明时 Ya-Huei （Cathy） Chin Enrique iglesia 江苏工业学院化工系 Department of Chemical Engineering University of California Berkeley 201 Gilman Hall Berkeley CA 94720USA Department of Chemical Engineering University of California Berkeley 201 Gilman Hall Berkeley CA 94720USA

＜正＞Conversion of natural gas with CO2, H2O, and O2 co-reactants over supported Ni, Pt, Rh, and Ru metal clusters are effective routes toward production of hydrogen and synthesis gas. Despite many research efforts, ... 详细信息

关键词： Methane activation Mechanism Oxygen coverage Platinum Catalysts

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Raman和TPR法研究丙烷氧化脱氢VOx/MoOx/Al2O3催化剂

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石油化工 2004年第Z1期33卷 540-542页

作者：戴洪兴何洪李佩珩孙继红 A T Bell E iglesia 北京工业大学环境与能源工程学院应化系北京100022 Chemical Sciences Divisions Lawrence Berkeley National Laboratory and Chem.Eng.Dept.Univ.of CaliforniaBerkeleyCalifornia 94720-1462

采用原位激光拉曼和程序升温还原法研究了VOx分散于载有单层MoOx(4.8 Mo/nm2)的Al2O3上丙烷氧化脱氢.比较了这些催化剂和VOx/Al2O3的脱氢速率和选择性.在一定VOx表面密度下,每克VOx/MoOx/Al2O3催化剂的脱氢反应速率比VOx/Al2O3催化剂的... 详细信息

采用原位激光拉曼和程序升温还原法研究了VOx分散于载有单层MoOx(4.8 Mo/nm2)的Al2O3上丙烷氧化脱氢.比较了这些催化剂和VOx/Al2O3的脱氢速率和选择性.在一定VOx表面密度下,每克VOx/MoOx/Al2O3催化剂的脱氢反应速率比VOx/Al2O3催化剂的高1.5～2倍.中间层MoOx通过抑制丙烷和丙烯燃烧反应速率增加了丙烯选择性.偏钒酸铵作钒源,使用钒的醇盐制备催化剂可使VOx形成高分散的单钒酸根和多聚钒酸根配位结构、减少V2O5晶粒的生成及促使V-O-Mo键的形成.催化剂的C3H6形成速率与其H2消耗速率成线性关系.

关键词：丙烷氧化脱氢负载型钒钼氧化物催化剂激光拉曼程序升温还原

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GTP-bound Rab3A exhibits consecutive positive and negative roles during human sperm dense-core granule exocytosis

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Journal of Molecular Cell Biology 2014年第4期8卷 286-298页

作者： Matias A. Bustos Carlos M. Roggero Paola X. De la iglesia.Luis S. Mayorga Claudia N. Tomes Instituto de Histologia y Embriologia IHEM-CONICET Facultad de Ciencias Medicas Universidad Nacional de Cuyo Mendoza Argentina Department of Biophysics UT Southwestern Medical Center Dallas TX USA Servicio de Patologla Hospital Italiano de Buenos Aires Buenos Aires Argentina

Exocytosis of mam maUan sperm dense-core secretory granule relies on the same fusion molecules as all other secretory cells; one such molecule is the small GTPase Rab3A. Here, we report an in-depth biochemical characterization of the role of Rab3A in secretion by scrutinizingthe exocytotic response of streptolysin O-permeabiUzed human sperm to the acute application of a number of Rab3A-containing constructs and correlating the findings with those gathered with the endogenous protein. Full length, geranyigeranyiated, and active Rab3A elicited human sperm exocytosis perse. With Rab3A/Rab22A chimeric proteins, we demonstrated that the carboxy-terminal domain of the Rab3A molecule was necessary and sufficient to promote exocytosis, whereas its *** prevented calcium-triggered secretion. Interestingly, full length Rab3A halted secretion when added after the docking of the acrosome to the plasma membrane. This effect depended on the inability of Rab3A to hydrolyze GTP. We combined modified immunofluorescence and acrosomal staining protocols to detect membrane fusion and the activation status of endogenous Rab3 simultaneously in individual cells, and found that GTP hydrolysis on endogenous Rab3 was mandatory for fusion pores to open. Our findings contribute to establishing that Rab3 modulates regulated exocytosis differently depending on the nucleotide bound and the exocytosis stage under study.

关键词： Rab3 cycle GTP hydrolysis exocytosis acrosome calcium sperm

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子宫内膜异位症术后慢性尿潴留及骨盆底肌张力过高系列报道

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世界核心医学期刊文摘（妇产科学分册） 2006年第5期2卷 9-9页

作者： Gehrich A.P Aseff J.N iglesia.C.B 朱国栋 8513 Cameron Street Silver Spring MD 20910 United States

The purpose of this study was to evaluate 4 cases of chronic urinary retention and pelvic floor muscle spasms after surgery for endometriosis. Study design: These patients underwent a complete history, physical exam, and diagnostic work up. The results were analyzed with regards to type and extent of inciting surgery, diagnostic findings, postoperative recovery, and treatment success. Results: The patients’ mean age was 39.5 years and all had undergone various surgical interventions for endometriosis. In addition to urinary retention, all deve loped debilitating pelvic floor muscle spasm postoperatively. Physical exam revealed pelvic floor hypertonicity and urodynamics indicated hypoactive detrusor contractility. Neurodiagnostic testing gave evidence of neuropathy in all subjects. Conclusion: Extensive endometriosis surgery may pose a risk for postoperative bladder dysfunction and pelvic floor muscle spasm.

关键词：子宫内膜异位症盆底肌张力过高慢性尿潴留骨盆底肌无力膀胱功能诊断试验尿动力学病史询问

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