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国际医学放射学杂志 2015年第4期 403-403页

作者： T.Breidthardt E.F.Cox i.squire A.Odudu N.F.Omar M.T.Eldehni 麻智慧 Department of Renal Medicine Royal Derby Hospita

摘要目的研究慢性心力衰竭(HF)病人的肾功能与肾灌注及肾实质结构(T1弛豫)间的关系。方法经过伦理委员会(iRB)批准,根据HF和肾功能的状态入组40名参与者

关键词：心肾综合征磁共振成像病理生理学慢性心力衰竭伦理委员会肾功能弛豫肾实质肾皮质负相关

Molecular characterization of an outbreak-involved Bacillus anthracis strain confirms the spillover of anthrax from West Africa

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infectious Diseases of Poverty 2024年第1期13卷 93-94页

作者： Shuchao Wang Roland Suluku Mohamed B.Jalloh Ahmed F.Samba Baogui Jiang Yubiao Xie Doris Harding Mengyao Zhang Foday Sahr Mahmud E.Sesay James S.squire Mohamed A.Vandi Moinina N.Kallon Shoufeng Zhang Rongliang Hu Yuee Zhao Zhiqiang Mi Changchun Veterinary Research institute Chinese Academy of Agricultural Sciences Changchun China Department of Animal Sciences School of Agriculture and Food Sciences Njala University Njala Sierra Leone Department of Microbiology College of Medicine and Allied Health Sciences University of Sierra Leone Freetown Sierra Leone Ministry of Agriculture and Food Sciences Freetown Sierra Leone Beijing institute of Microbiology and Epidemiology Beijing China Ministry of Health and Sanitation Freetown Sierra Leone Beijing institute of Biotechnology Beijing China

Background Anthrax,a zoonotic disease caused by the spore-forming bacterium Bacillus anthracis,remains a major global public health concern,especially in countries with limited *** Leone,a West African country historically plagued by anthrax,has almost been out of report on this disease in recent *** this study,we described a large-scale anthrax outbreak affecting both animals and humans and attempted to characterize the *** The causative agent of the animal outbreak in Port Loko District,Sierra Leone,between March and May 2022 was identified using the nanopore sequencing technique.A nationwide active surveillance was implemented from May 2022 to June 2023 to monitor the occurrence of anthrax-specific symptoms in *** cases were subsequently verified using quantitative polymerase chain ***-genome sequencing was accomplished by combining long-read and short-read sequencing *** phylogenetic analysis was performed based on the full-chromosome single nucleotide *** The outbreak in Port Loko District,Sierra Leone,led to the death of 233 animals between March 26th and May 16th,*** ruled out the initial suspicion of Anaplasma species and successfully identified *** as the causative agent of the *** a result of the government's prompt response,out of the 49 suspected human cases identifed during the one-year active surveillance,only 6 human cases tested positive,all within the frst month after the official declaration of the *** phylogenetic analysis indicated that the BaSL2022 isolate responsible for the outbreak was positioned in the ***.153 clade within the TransEuroAsian group of *** We successfully identifed a large-scale anthrax outbreak in Sierra *** causative isolate of ***,BaSL2022,phylogenetically bridged other lineages in ***.153 clade and neighboring genetic groups,***.144 and ***.148,

关键词： Molecular identification Anthrax Bacillus anthracis Sierra Leone Phylogeny Single nucleotide polymorphism

Defining sustainable limits during and after intensification in a maritime agricultural ecosystem

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Ecosystem Health and Sustainability 2017年第8期3卷 15-31页

作者： Geoffrey R.squire Ecological Sciences James Hutton InstituteDundeeUK

introduction:intensification of agricultural ecosystems in the 20th century proceeded by a series of innovations that initially ensured food security,but had negative consequences for the in-field and wider environments.A case study in the north Atlantic zone maritime cropland of the UK identified three phases:(1)reorganization between 1940 and 1960,(2)intensification leading to tripling of grain output(1960-1990),and(3)a leveling of output(1990-2015).Outcomes:innovations that caused the changes together with their effect on life forms,ecological processes and the evolving social,economic and biophysical conditions are *** to design future sustainable systems are hampered by the absence of a baseline before intensification,by inadequate knowledge of in-field processes,and by uncertainty over"safe ranges"in which processes can operate without causing long-term system *** ranges are examined for three attributes recorded over all three phases,namely grain output,fertilizer input and the wild seedbank *** lower limits for grain and nitrogen were quantified as those that ensure grain *** upper limits were identified as those that were economically acceptable to farming in the face of major external perturbations related to food policy and environmental *** these upper limits,fields can maintain a generalist wild species seedbank that supports a farmland food ***:Some properties of the ecosystem therefore attained stability in phase ***,evidence of degrading soil,increasing pesticide use to maintain yield and collapse of specialist plant functions such as nitrogen fixation and pollination,suggest the system is moving toward a phase of decline.

关键词： Ecosystem services intensification resilience safe limits biodiversity

Behavioral and cognitive neuroscience = 行为和认知神经科学 edited by Larry squire ... [et al.].

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Hepatitis B virus is degraded by autophagosome-lysosome fusion mediated by Rab7 and related components

丛书名：科爱传播. 生命科学

2009年

作者： edited by Larry squire ... [et al.].

全书共分7个部分，覆盖神经科学领域的各个方面。

ISBN: (纸本)9787030241559

全书共分7个部分，覆盖神经科学领域的各个方面。

关键词： Neuropsychology.

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Protein & Cell 2019年第1期10卷 60-66页

作者： Yong Lin Chunchen Wu Xueyu Wang Thekla Kemper Anthony squire Matthias Gunzer Jiming Zhang Xinwen Chen Mengji Lu institute of Virology University Hospital EssenUniversity of Duisburg-Essen45117 EssenGermany State Key Laboratory of Virology Wuhan Institute of VirologyChinese Academy of ScienceWuhan 430071China institute for Experimental immunology and imaging University Hospital EssenUniversity Duisburg-Essen45117 EssenGermany Department of infectious Diseases Huashan HospitalFudan UniversityShanghai 200040China

Dear Editor,With an estimated 240 million chronically infected people worldwide,hepatitis B virus(HBV)infection is a major public health problem(Schweitzer et al.,2015).Despite more than 30 years of in tense research,... 详细信息

关键词： Editor people HBV

Nervous system development. 导读版

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Fundamental neuroscience 3rd ed

丛书名：科爱传播. 生命科学

2009年

作者： Larry squire

"导读版"--Cover.

ISBN: (纸本)9787030241580

"导读版"--Cover.

关键词： Neurosciences.

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Ecosystem health towards sustainability

2009年

作者： edited by Larry squire ...[et al.]

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Ecosystem Health and Sustainability 2015年第1期1卷 7-22页

作者： Yonglong Lu Ruoshi Wang Yueqing Zhang Hongqiao Su Pei Wang Alan Jenkins Rober C.Ferrier Mark Bailey Geoff squire State Key Laboratory of Urban and Regional Ecology Research Center for Eco-Environmental SciencesChinese Academy of SciencesBeijing 100085 China University of Chinese Academy of Sciences Beijing 100049 China Centre for Ecology and Hydrology Wallingford OX108BB United Kingdom James Hutton institute Aberdeen AB158QH ScotlandUnited Kingdom

Ecosystems are becoming damaged or degraded as a result of stresses especially associated with human activities.A healthy ecosystem is essential to provide the services that humans and the natural environment require and has tremendous social and economic *** of the definition of ecosystem health includes what constitutes health and what it means to be *** evaluate ecosystem health,it is necessary to quantify ecosystem conditions using a variety of *** this paper,the main principles and criteria for indicator selection,classification of indicators for different kinds of ecosystems,the most appropriate indicators for measuring ecosystem sustainability,and various methods and models for the assessment of ecosystem health are ***,sustainability,and resilience are considered to be critical factors for ecosystem health and its *** integration of ecological understanding with socioeconomic,biophysical,biogeochemical,and public-policy dimensions is still the primary challenge in this field,and devising workable strategies to achieve and maintain ecosystem health is a key future challenge.

关键词： assessment methodology ecological indicator ecosystem functioning ecosystem health ecosystem sustainability resilience

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设计师的窗栅演绎法

缤纷 2014年第4期 154-157页

作者： squire & Partners 张晓

受到上世纪前半叶现代主义风潮的影响，如今每当我们谈及现代建筑的时候，总是或多或少在潜意识中浮现出剥离了文化符号的抽象空间，毫无装饰的平坦立面、不加掩饰的结构、“纯净”的色块……然而，尽管汉诺威大街1O号这栋狭窄的8层建... 详细信息

受到上世纪前半叶现代主义风潮的影响，如今每当我们谈及现代建筑的时候，总是或多或少在潜意识中浮现出剥离了文化符号的抽象空间，毫无装饰的平坦立面、不加掩饰的结构、“纯净”的色块……然而，尽管汉诺威大街1O号这栋狭窄的8层建筑作为一家当代艺术画廊“理当”现代主义，但它却并没选择激进地与过去割袍断义。相反，设计者选择以当代语境下的叙事方式来演绎本国、本地的人文印记，试图以此构建起与历史、文化传承的某种联系。

关键词：演绎法设计师现代主义现代建筑文化符号当代艺术叙事方式当代语境

通过羊膜穿刺对2,036例妊妇进行产前诊断和妊娠结果的研究

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国际遗传学杂志 1983年第2期06卷 97-100页

作者： squire JA 戴德林

进行羊膜穿刺特别重要的问题是羊膜穿刺后妊娠的安全和后果,检测异常的发生率和意义,技术标准化以及提供和改进对患者的服务。本文报告1972～1980年间在Ken-nedy-Galton 中心研究2,000例以上羊膜穿刺的结果。

关键词：羊膜穿刺穿刺术产前诊断羊水培养非整倍体非整元体 NTD