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Six-Minute Walk Test in Patients with Rheumatoid Arthritis

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Open Journal of Rheumatology and Autoimmune Diseases 2019年第1期9卷 14-24页

作者： sandor Balsamo Ana Paula Monteiro Gomides Licia Maria Henrique da Mota Frederico Santos de Santana Raphaela Franco Miranda Talita Yokoy Luciana Muniz Leopoldo Luiz Santos-Neto Universidade de Brasília (UnB) Brasília Brazil Laboratório de Aptidã o Física e Reumatologia do Hospital Universitário de Brasília (LAR/HUB) Brasília Brazil Grupo de Estudo e Pesquisa em Exercício de Forç a e Saúde (GEPEEFS) Brasília Brazil Curso Superior de Educaç o Física Centro Universitário UNIEURO Brasília Brazil Ambulatório de Reumatologia Hospital Universitário de Brasília (HUB) Brasília Brazil

Background: The 6-minute walk test (6TC) was initially used as an instrument for assessing physical and cardiorespiratory capacity, but is currently being used to monitor treatments, and compare physical interventions and prognostic evaluation. Although already recognized as a research method in several specialties, 6TC has not been used in rheumatology. Patients with rheumatoid arthritis (RA) may have impaired functional capacity as well as increased cardiovascular mortality. An adequate functional evaluation of these patients is necessary and the 6TC may be useful in this sense. Objective: The aim of this study was to perform the 6-minute walk test in RA patients and to compare the performance with a control group. Method: A cross-sectional study was carried out in which the sample consisted of 85 women, 46 patients with rheumatoid arthritis and 39 healthy controls. A descriptive analysis of the data was performed. One-Way ANOVA methodology was used to compare the patient and control groups followed by the graphic analysis. Results: The distance walked on the 6TC by RA patients was on average 522.2 meters. in the distance control group found in the 6TC was on average 628.8 meters, the difference being statistically significant. Conclusion: in this study the distance covered in 6TC by women with RA was lower than that of healthy women of the same age.

关键词： 6-Minute Walk Test Rheumatoid Arthritis Functional Capacity Physical Capacity Cardiorespiratory Capacity Person Performed

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多拉报告第1版

The Effect of Childhood Obesity on Social Welfare

1980年

作者：（匈）拉多·山多尔（Rado sandor）柴鹏飞译

书名原文:Dora Jelenti... 详细信息

ISBN: (纸本)3067·109

书名原文:Dora Jelenti...

关键词：第二次世界大战学科:史料

来源：汇雅图书（南通市图书馆... 评论

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Journal of Modern Accounting and Auditing 2011年第7期7卷 758-766页

作者： Robert sandor Szucs Zsolt Csapo Szolnok University College Hungary University of Debrecen Hungary

The young generation is the most influenced and vulnerable segment of the market. Food with high level of fat, sugar and/or salt are popularised for this segment. At the same time nearly seven people die of obesity or from complications of obesity in Hungary each hour—-one every nine minutes. Approximately 119 million Americans, or 64.5%, of adult Americans are either overweight or obese. 17.5 million obese young person live in the European Union. The result is the drastic elevation of the hygienic expenses. The average health care cost of overweight persons is higher by 42% than normal bodyweight ones. Per capita spending on fast foods is unbelievable and rising. The value of average spending was 2.5 € in 2002. Fast food sales continue to boom despite warnings about obesity. The consumption of these products can contribute to the increased level of childhood obesity. 12% of young person"s visited a fast food restaurant at least with a weekly regularity. The value is 16.9% in case of young men higher than in case of young ladies (8.1%) to our research. We can state the respondents underestimate the costs of fast foods.

关键词：肥胖社会福利儿童人均消费快餐食品医疗费用弱势群体市场影响

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发酵完全指南

发酵完全指南

EFNS偏头痛药物治疗指南——EFNS特别工作组修订报告

作者： (美)桑德尔·埃利克斯·卡茨(sandor Ellix Katz)

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国际脑血管病杂志 2010年第1期18卷 4-15页

作者： S.Evers J. Afra A. Frese P.J.Goaasby M.Linde A.May P.S.sandor 吴宏赟(译) 胡志强(译) 侯书伟(译) Department of Neurology University of Miimter Mtimter Germany National institute of Neurosurgery Budapest Hmagary Academy of Manual Medicine Mtinster Germany Headache Group Department of Neurology Unixersity of California San Francisco CA USA UCL Institute of Neurology Queen Square London UK Cephalea Headache Centre Lakarhuset S6dra vagen Gothenburg Sweden Department of Neurology University of Hamburg Germany hDepartment of Neurology Unixersity of Zurich Switzerland 山东省中医院神经内科济南250011 山东省中医院针灸科济南250011

背景偏头痛是最常见的失能性神经疾病之一，会严重损害患者的生活质量。目的在文献检索和专家共识的基础上，对特殊类型偏头痛综合征的各种药物治疗方案提供循证或专家推荐。方法从现有的所有医学参考文献系统中筛选出关于有先兆型或无... 详细信息

背景偏头痛是最常见的失能性神经疾病之一，会严重损害患者的生活质量。目的在文献检索和专家共识的基础上，对特殊类型偏头痛综合征的各种药物治疗方案提供循证或专家推荐。方法从现有的所有医学参考文献系统中筛选出关于有先兆型或无先兆型偏头痛以及偏头痛样综合征的各种类型临床资料进行分析。根据欧洲神经病学学会联盟（European Federation of Neurological Societies，EFNS）制定的推荐意见分级方案对这些研究结果进行评价，从而确定A级、B级或C级推荐和良好的临床实践要点。推荐意见推荐口服非甾体消炎药（non-steroidalanti-inflammatory drug，NSAiD）和曲坦类药物用于偏头痛发作的急性期治疗。用药方案应遵循分层治疗观念。在口服NSAiD和曲坦类药物之前，推荐口服甲氧氯普胺或多潘立酮。在极重度偏头痛发作时，首选静脉注射乙酸水杨酸或皮下注射舒马曲坦。偏头痛持续状态可用类固醇治疗，虽然并非总是有效；也可用二氢麦角胺治疗。β-受体阻滞药（普萘洛尔和美托洛尔）、氟桂利嗪、丙戊酸和托吡酯可作为偏头痛预防性治疗的首选用药，其次可选用阿米替林、萘普生、蜂斗菜烯碱和比索洛尔。

关键词：循证医学偏头痛预防曲坦类药物

磷对冬小麦(兼及春小麦)不同生育阶段地上部及根系干物质生产的影响

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麦类作物学报 1984年第5期 32-34+36页

作者： P.J.Sutton G.A.Peterson D.H.sandor 马长德

人们早就知道,磷是植物必需的营养元素,它在植物细胞的能量转化,呼吸和光合作用中具有重要作用。然而,有关冬小麦一生中需磷临界期的报道却很少,也很少涉及冬小麦不同生育阶段中磷对获得高产的作用的内容。本试验的目的,一是确定在冬小... 详细信息

人们早就知道,磷是植物必需的营养元素,它在植物细胞的能量转化,呼吸和光合作用中具有重要作用。然而,有关冬小麦一生中需磷临界期的报道却很少,也很少涉及冬小麦不同生育阶段中磷对获得高产的作用的内容。本试验的目的,一是确定在冬小麦生长的过程中从营养液中除去磷之后,对干物质生产

关键词：地上部植株根系干重干物质冬小麦冬麦籽粒产量生育阶段生育时期

Evolution of disease phenotype in adult and pediatric onset Crohn's disease in a population-based cohort

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World Journal of Gastroenterology 2013年第14期19卷 2217-2226页

作者： Barbara Dorottya Lovasz Laszlo Lakatos Agnes Horvath istvan Szita Tunde Pandur Michael Mandel Zsuzsanna Vegh Petra Anna Golovics Gabor Mester Mihaly Balogh Csaba Molnar Erzsebet Komaromi Lajos sandor Kiss Peter Laszlo Lakatos First Department of Medicine Semmelweis University Department of Medicine Csolnoky F Province Hospital Department of Pediatrics Csolnoky F Province Hospital Department of Medicine Grof Eszterhazy Hospital Department of infectious Diseases Magyar Imre Hospital Department of Gastroenterology Municipal Hospital

AiM:To investigate the evolution of disease phenotypein adult and pediatric onset Crohn's disease(CD) populations,diagnosed between 1977 and ***:Data of 506 incident CD patients were analyzed(age at diagnosis:28.5 years,interquartile range:22-38 years).Both in-and outpatient records were collected prospectively with a complete clinical follow-up and comprehensively reviewed in the population-based Veszprem province database,which included incident patients diagnosed between January 1,1977 and December 31,2008 in adult and pediatric onset CD *** phenotype according to the Montreal classification and long-term disease course was analysed according to the age at onset in time-dependent univariate and multivariate ***:Among this population-based cohort,seventy-four(12.8%) pediatric-onset CD patients were identified(diagnosed ≤ 17 years of age).There was no significant difference in the distribution of disease behavior between pediatric(B1:62%,B2:15%,B3:23%) and adult-onset CD patients(B1:56%,B2:21%,B3:23%) at diagnosis,or during ***,the probability of developing complicated disease behaviour was 49.7% and 61.3% in the pediatric and 55.1% and 62.4% in the adult onset patients after 5-and 10-years of ***,time to change in disease behaviour from non stricturing,non penetrating(B1) to complicated,stricturing or penetrating(B2/B3) disease was not significantly different between pediatric and adult onset CD in a Kaplan-Meier *** year of diagnosis(P = 0.04),ileal location(P ianal disease(P ing(P = 0.038) and need for steroids(P iated with presence of,or progression to,complicated disease behavior at diagnosis and during follow-up.A change in disease location was observed in 8.9% of patients and it was associated with smoking status(P = 0.01),but not with age at ***:Long-term evolution of disease behavior was not different in pediatric-a

关键词： Crohn’s disease Age at diagnosis Disease behavior Disease course

integrative genomics reveals paths to sex dimorphism in Salix purpurea L

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Horticulture Research 2021年第1期8卷 2305-2318页

作者： Brennan Hyden Craig H.Carlson Fred E.Gouker Jeremy Schmutz Kerrie Barry Anna Lipzen Aditi Sharma Laura sandor Gerald A.Tuskan Guanqiao Feng Matthew S.Olson Stephen P.DiFazio Lawrence B.Smart Horticulture Section School of Integrative Plant ScienceCornell UniversityCornell AgriTechGenevaNYUSA Floral and Nursery Plants Research Unit US National ArboretumUnited States Department of AgricultureAgricultural Research ServiceBeltsvilleMDUSA United States Department of Energy Joint Genome InstituteBerkeleyCAUSA HudsonAlpha institute for Biotechnology HuntsvilleALUSA The Center for Bioenergy innovation Oak Ridge National LaboratoryOak RidgeTNUSA Department of Biology Texas Tech UniversityLubbockTXUSA Department of Biology West Virginia UniversityMorgantownWVUSA

Sex dimorphism and gene expression were studied in developing catkins in 159 F 2 individuals from the bioenergy crop Salix purpurea,and potential mechanisms and pathways for regulating sex development were *** expression,eQTL,bisulfite sequencing,and network analysis were used to characterize sex dimorphism,detect candidate master regulator genes,and identify pathways through which the sex determination region(SDR)may mediate sex *** genes are presented as candidates for master regulators of sex,supported by gene expression and network *** include genes putatively involved in hormone signaling,epigenetic modification,and regulation of *** analysis revealed a suite of transcription factors and genes involved in secondary metabolism and floral development that were predicted to be under direct control of the sex determination ***,data from bisulfite sequencing and small RNA sequencing revealed strong differences in expression between males and females that would implicate both of these processes in sex dimorphism *** data indicate that the mechanism of sex determination in Salix purpurea is likely different from that observed in the related genus *** further demonstrates the dynamic nature of SDRs in plants,which involves a multitude of mechanisms of sex determination and a high rate of turnover.

关键词： purpurea metabolism likely