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疑有急性阑尾炎的妊娠病人:MRi对阴性剖腹探查率及阑尾穿孔率的作用

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国际医学放射学杂志 2009年第3期 278-278页

作者： i.pedrosa M.Lafornara P.V.Pandharipande J.D.Goldsmith N.M.Rofsky 罗伟 Department of Radiology Beth Israel Deaconess Medical CenterHarvard Medical SchoolOne Deaconess RoadBostonMA 02215

目的探讨MRi在疑有急性阑尾炎(acuteappendicitis,AA)的妊娠病人阴性剖腹探查率(negativelaparotomy rate,NLR)与阑尾穿孔率(perforation rate,PR)中的作用,并评价CT在此方面的应用。方法本研究获机构审查委员会批准,符合HiPAA。回顾性... 详细信息

目的探讨MRi在疑有急性阑尾炎(acuteappendicitis,AA)的妊娠病人阴性剖腹探查率(negativelaparotomy rate,NLR)与阑尾穿孔率(perforation rate,PR)中的作用,并评价CT在此方面的应用。方法本研究获机构审查委员会批准,符合HiPAA。回顾性分析2002年3月—2007年8月间,临床怀疑AA并进行了MRi检查的148例连续的妊娠病人(平均年龄29岁,范围14～42岁;平均胎龄20周,范围4～37周)。

关键词： MRi 阑尾穿孔病人剖腹探查阑尾炎肠疾病

肾功能损害肾脏肿瘤病人的动脉自旋标记MRi特性:初步经验

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国际医学放射学杂志 2012年第2期 204-204页

作者： i.pedrosa K.Rafatzand P.Robson A.A.Wagner M.B.Atkins N.M.Rofsky 李华兵 Department of Radiology Beth Israel Deaconess Medical Center and Harvard Medical School330 Brookline AveBostonMA02215USA

目的回顾性评价动脉自旋标记(ASL)MRi对肾功能损害病人的肾脏肿瘤血管评估的可行性。方法 2007年5月—2008年11月,对67例中的11例因中度至重度慢性或急性肾功能衰竭的连续病人行未增强ASL-MRi检查,以评

关键词： MRi 肾肿瘤灌注肾功能不全肾源性系统性纤维化

胰腺癌的多期相CT结构报告:分期和手术计划制定的潜在影响

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国际医学放射学杂志 2015年第2期 179-179页

作者： O.R.Brook A.Brook C.M.Vollmer T.S.Kent N.Sanchez i.pedrosa 卢忠飞 Department of Radiology University of Texas Southwestern Medical Center 2201 Inwood Rd 2nd Floor Suite DallasTX 75390-9085

摘要目的比较多期相CT的结构化及非结构化报告对胰腺癌的分期及其对手术可切除性评估的影响。材料与方法该回顾性研究经机构伦理委员会同意,符合HiPAA,所有病

关键词：胰腺癌多期 CT

应用3TMR高空间分辨力动态增强检查预测前列腺癌突破包膜

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国际医学放射学杂志 2012年第6期 610-610页

作者： B.N.Bloch E,M.Genega D.N.Costa i.pedrosa M.P.Smith H.Y.Kressel 赵阳 Department of Radiology University of Texas Southwestern Medical Center5323 Harry Hines BlvdDallasTX 75390-8896USA

目的评估通过3TMR动态增强(DCE)检查联合以直肠内线圈(ERC)为接收线圈的T2W成像预测前列腺癌突破包膜的诊断价值。方法本研究已得到伦理审查委员会批准。108例行前列腺全切术病人术前均行3TMR直肠内线圈前列腺检查。分别获得全部病人的... 详细信息

目的评估通过3TMR动态增强(DCE)检查联合以直肠内线圈(ERC)为接收线圈的T2W成像预测前列腺癌突破包膜的诊断价值。方法本研究已得到伦理审查委员会批准。108例行前列腺全切术病人术前均行3TMR直肠内线圈前列腺检查。分别获得全部病人的T2W快速自旋回波影像和动态增强3D梯度回波影像。由诊断经验不同的医师分别对影像进行解读,并对各组结果进行分析。将基于MR所得的分期结果与根治术后的病理结果进行对照。所得结果进行描述性统计计算,通过ROC曲线下面积确定结果预测前列腺癌突破包膜的发生和前列腺癌的分期。结果整体上利用文中方法预测前列腺癌突破包膜的敏感度、特异度、阳性预测值和阴性预测值分别为75%、92%、79%和91%。全部医师、经验丰富和缺乏经验的医师分期诊断的准确度分别为86%、80%和91%。结论在3T直肠内线圈MR检查中联合应用动态增强和T2Wi检查前列腺,是一种适用于不同层次医师在病人治疗前预测前列腺癌突破包膜的准确分期方法。

关键词：前列腺癌 MRi 肿瘤分期临床解释学习曲线

小鼠肾细胞癌模型的MR动脉自旋标记成像测量的肿瘤灌注与抗血管生成治疗反应间是否具有相关性?

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国际医学放射学杂志 2009年第4期32卷 391-391页

作者： R.S.Bardach D. C.A lsop i.pedrosa S.A .Solazzo X. Wang R. P.Marquis 曹毅（译）刘竞艳（校） Minimally invasive Tumor Therapy Lab Beth israel Deaconess Medical Center Harvard Medical School 1 Deaconess Rd W CC 308-B Boston MA 02215 USA. 不详

目的确定抗血管生成治疗前及治疗早期动脉自旋标记（ASL）MRi表现可否预测晚期发生的治疗抵抗。方法该方案经动物保护和应用委员会批准。将Caki～1、A498及786—0人类。肾细胞癌异种移植到39只裸鼠中。一旦肿瘤长到12mm,每天对裸鼠按照8... 详细信息

目的确定抗血管生成治疗前及治疗早期动脉自旋标记（ASL）MRi表现可否预测晚期发生的治疗抵抗。方法该方案经动物保护和应用委员会批准。将Caki～1、A498及786—0人类。肾细胞癌异种移植到39只裸鼠中。一旦肿瘤长到12mm,每天对裸鼠按照80mg／kg体质量注射1次索拉非尼。在治疗前及治疗后14d时采集ASL影像,并对786—0及A498的裸鼠增加成像检查（3d～12周）。分析平均m流量值及血流量在空间分布上的差异．并与组织病理学的存活性及微血管密度进行比较。对肿瘤平均血流量的差异进行t检验,

关键词：动脉自旋标记抗血管生成 MRi表现治疗反应肾细胞癌肿瘤成像平均血流量

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Detection of 4p16.3 deletion and 11p15.5p15.4 gain in a boy by comparative genomic hybridization array:A case report

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World Journal of Clinical Cases 2024年第8期12卷 1517-1522页

作者： işın Kaya Medical Genetics Bakırçay UniversityÇiğli Education ve Training Hospitalİzmir 35620Turkey

BACKGROUND Nonallelic homologous recombination(NAHR)of segmental duplications or low copy repeats(LCRs)result in DNA gain/loss and play an important role in the origin of genomic disorders.CASE SUMMARY A 3-year-old boy was referred for genetic analysis.Comparative genomic hybrid-ization array analysis revealed a loss of 3776 kb in the 4p16.3 chromosomal region and a gain of 3201 kb in the 11p15.5p15.4 chromosomal region.CONCLUSiON Genomic imbalances caused by NAHR in LCRs result in deletion and duplication syndromes.

关键词： Wolf-Hirschhorn syndrome Silver-Russell syndrome Recurrent rearrangements Case report

Taxonomy,distribution,and contemporary exposure of terrestrial mammals to floods and human pressure across different areas for biodiversity conservation in China

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integrative Zoology 2024年第3期19卷 458-467页

作者： Roman SHARNUUD Eric i.AMECA MOE Key Laboratory for Biodiversity Science&Ecological Engineering College of Life SciencesBeijing Normal UniversityBeijingChina Climate Change Specialist Group Species Survival CommissionInternational Union for Conservation of NatureGlandSwitzerland

A significant research focus is placed on identifying animal species and areas at future risk to human-induced alterations of the environment and long-term changes in climatic conditions.Yet,the extent to which exposure to extreme climatic events and intense human pressure can increase the risk of harmful impacts on species remains poorly investigated.Focusing on terrestrial mammals in China,one of the world’s megadiverse countries,we investigated patterns of contemporary exposure to floods and human pressures and determined their taxonomic representation and distribution across three major area-based conservation schemes,namely,national nature reserves(NNRs),priority areas for biodiversity conservation(PABCs),and key biodiversity areas(KBAs).Among the 440 species assessed with moderate or high exposure to floods,327(∼75%)also qualified as moderate or high in exposure to intense human pressure.These species mainly belong to the orders Chiroptera,Eulipotyphla,and Rodentia.Likewise,there were 305,311,and 311 species with moderate or high exposure to flood and intense human pressure represented across NNRs,PABCs,and KBAs,respectively.Our findings support the prioritization of KBAs for expansion of site-based protection efforts such as NNRs in China,considering threats to species from exposure to adverse effects from both extreme climate and human pressure.

关键词： conservation floods human pressure mammals taxonomy

Study of the Conversion of Postconsumer Polystyrene on CeO₂/HZSM-5 Type Materials

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Journal of Materials Science and Chemical Engineering 2024年第4期12卷 29-41页

作者： Mirna Oliveira Sant’Ana Anne Michelle Garrido pedrosa Marcelo José Barros de Souza Graduate Program in Chemical Engineering at UFS Federal University of Sergipe (UFS) S&#227o Crist&#243v&#227o Brazil Department of Chemistry Federal University of Sergipe S&#227o Crist&#243v&#227o Brazil

The catalytic conversion of polystyrene (PS) was studied in the presence of the materials type HZSM-5, CeO2, 10% CeO2/HZSM-5 and 20% CeO2/HZSM-5, which were characterized by scanning electron microscopy (SEM), X-ray diffraction (XRD) and nitrogen adsorption at 77K. The catalytic tests were performed via thermogravimetric analysis (TG) at heating rates of 5, 10 and 20˚C min−1 in a temperature range from 30˚C to 900˚C. For the tests, a ratio of 30% by mass of each catalytic material mixed with PS was used and the activation energy of the degradation process was determined by the Vyazovkin method. The obtained results showed that the addition of the catalyst to the PS in general reduced its degradation temperature. The 10% CeO2/HZSM-5 catalyst showed greater efficiency, as it resulted in lower activation energy for PS degradation. Thus, the combination of CeO2 with HZSM-5 resulted in materials with potential for application in the catalytic degradation of polystyrene and the results indicate that the production of a composite material can be a good strategy to generate an increase in catalytic activity and a decrease in energy process activation.

关键词： HZSM-5 Zeolite Cerium Oxide Polystyrene Pyrolysis

Are population cycles recovering?

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integrative Zoology 2024年第3期19卷 538-547页

作者： Vasily D.YAKUSHOV Boris i.SHEFTEL A.N.Severtsov institute of Ecology and Evolution of the Russian Academy of Sciences MoscowRussia

The dynamics of populations of small mammals of Central Siberia was analyzed.The studies were carried out at the Yenisei ecological station“Mirnoye”of the A.N.Severtsov institute of Ecology and Evolution,Russian Academy of Sciences.The time series analysis was performed by the wavelet transform using the statistical data processing language R.in the 20th century,the dynamics of the population of the community and some of its constituent species(Sorex araneus;S.caecutiens;S.isodon;S.tundrensis;S.minutus;Craseomys rufocanus;Clethrionomys rutilus;Microtus oeconomus;M.agrestis)were characterized by a 4-year periodicity.The type of dynamics changed to noncyclic by the nineties,but by 2022,four species(S.araneus,S.isodon,C.rutilus,and M.oeconomus)and the community as a whole showed a tendency toward recovery of population cycles.The remaining species were characterized by consistently low numbers with irregular low amplitude fluctuations.

关键词： population cycles small mammals time-series analysis wavelet transform