检索结果-南通市图书馆

Fungal dysbiosis predicts the diagnosis of pediatric Crohn's disease

World Journal of Gastroenterology 2018年第39期24卷 4510-4516页

作者： Mohammad i El Mouzan Kirill S Korolev Mohammad A Al Mofarreh Rajita Menon Harland S Winter Ahmad A Al Sarkhy Scot E Dowd Ahmad M Al Barrag Asaad A Assiri Department of Pediatrics King Saud UniversityRiyadh 11461Saudi Arabia Department of Pediatrics Supervisor of Prince Abdullah Bin Khalid Celiac Disease Research ChairKing Saud UniversityRiyadh 11461Saudi Arabia Bioinformatics Program Boston UniversityBostonMA 02215United States Al Mofarreh PolyClinic Riyadh 11423Saudi Arabia MassGeneral Hospital for Children BostonMA 02114United States MRDNA ShallowaterTX 79363United States Department of Microbiology King Saud UniversityRiyadh 11461Saudi Arabia

AiM To investigate the accuracy of fungal dysbiosis inmucosa and stool for predicting the diagnosis of Crohn's disease(CD). METHODS Children were prospectively enrolled in two medical centers: one university hospital and one private gastroenterology clinic in the city of Riyadh, Kingdom of Saudi Arabia. The children with confirmed diagnosis of CD by standard guidelines were considered cases, and the others were considered non-inflammatory bowel disease controls. Mucosal and stool samples were sequenced utilizing illumina MiSeq chemistry following the manufacturer's protocols, and abundance and diversity of fungal taxa in mucosa and stool were analyzed. Sparse logistic regression was used to predict the diagnosis of CD. The accuracy of the classifier was tested by computing the receiver operating characteristic curves with 5-fold stratified cross-validation under 100 permutations of the training data partition and the mean area under the curve(AUC) was calculated. RESULTS All the children were Saudi nationals. There were 15 children with CD and 20 controls. The mean age was 13.9(range: 6.7-17.8) years for CD children and 13.9(3.25-18.6) years for controls, and 10/15(67%) of the CD and 13/20(65%) of the control subjects were boys. CD locations at diagnosis were ileal(L1) in 4 and colonic(L3) in 11 children, while CD behavior was non-stricturing and non-penetrating(B1) in 12 and stricturing(B2) in 3 children. The mean AUC for the fungal dysbiosis classifier was significantly higher in stools(AUC = 0.85 ± 0.057) than in mucosa(AUC = 0.71 ± 0.067)(P ies were significantly more depleted in stools than mucosal samples, except for Saccharomyces cerevisiae and S. bayanus, which were significantly more abundant. Diversity was significantly more reduced in stools than in mucosa. CONCLUSiON We found high AUC of fungal dysbiosis in fecal samples of children with CD, suggesting high accuracy in predicting diagnosis of CD.

关键词： Fungiome Mycobiome Crohn’s disease inflammation Saudi children

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

牛顿革命

引用

作者： (美)i·B·科恩

来源：南通市图书馆图书评论

学校读者我要写书评

暂无评论

Friction Coefficient Displayed by the Scratch of Epoxy Composites Filled by Metallic Particles under the influence of Magnetic Field

引用

Materials Sciences and Applications 2015年第2期6卷 200-208页

作者： F. i. El-Zahraa G. T. Abdel-Jaber M. i. Khashaba W. Y. Ali Faculty of Engineering South Valley University Qena Egypt Faculty of Engineering Minia University Minya Egypt Faculty of Engineering Taif University Taif KSA

The wide use of epoxy composites as bearing materials in electronic appliances necessitates studying their frictional behaviour under the influence of magnetic field. Experiments were carried out to investigate the effect of magnetic field on the friction coefficient displayed by the scratch of epoxy composites filled by iron, copper and aluminium particles at different concentrations. it was observed that, for epoxy filled by the metallic fillers (iron, copper and aluminium), under the effect of the magnetic field, friction coefficient showed relative decrease then significantly increased with further increase of the intensity of the magnetic field. Besides, friction coefficient increased with increasing the content of the metallic fillers due to the decrease of the strength of the epoxy matrix. The values of friction coefficient displayed by epoxy filled by copper were lower than those observed for epoxy filled by iron. Filling epoxy by aluminium displayed lower friction coefficient than that observed for epoxy composites filled by iron and copper. This can be attributed to the charging of aluminium by positive charge when slid against steel. The resultant charge on the sliding surfaces was lower than that generated when epoxy was filled by iron and copper. in that condition, the adhesion of epoxy composites would be relatively weaker leading to the decrease of friction coefficient.

关键词： Friction Coefficient Epoxy Composites iron Copper Aluminium Magnetic Field Scratch

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

作者： i·阿西莫夫(i Asimov)

学校读者我要写书评

暂无评论

金属有机配合物的热致非线性光学特性的对比研究

引用

光学技术 2014年第4期40卷 335-338页

作者：张鹏飞浙江工商职业技术学院工学院浙江宁波315012

利用连续激光z扫描技术研究了两种新型金属有机配合物非线性材料在457nm、488nm和514nm三个激发波长下的热光效应。结合实验曲线和理论公式计算了这两种配合物溶液的热光系数dn/dT和热致非线性折射率n2的值。通过对比研究发现,材料的热... 详细信息

利用连续激光z扫描技术研究了两种新型金属有机配合物非线性材料在457nm、488nm和514nm三个激发波长下的热光效应。结合实验曲线和理论公式计算了这两种配合物溶液的热光系数dn/dT和热致非线性折射率n2的值。通过对比研究发现,材料的热致三阶非线性光学性质依赖于材料的分子结构和激发波长,Cu配合物的热光系数和热致非线性折射率的数值较大,且受激发波长的变化影响很小,而Pd配合物的热致非线性随激发波长的增大而减小,这主要是由两种化合物分子结构的差异导致其吸收光谱分布不同决定的。

关键词：金属有机配合物热致非线性折射率 z扫描

来源：

维普期刊数据库

同方期刊数据库评论

在线全文

学校读者我要写书评

暂无评论

Study of moisture migration in clay soils considering rate of freezing

引用

Journal of Groundwater Science and Engineering 2014年第4期2卷 35-40页

作者： Kudryavtsev S A Kazharskii A V Goncharova E D Berestianyi i B Far Eastern State Transport University (FESTU) Research Construction and Engineering Company “DV-GEOSYNTHETiCS”

The paper presents some methods of numerical modelling and a study of moisture changing in frozen clay soils considering rates of freezing in the foundation. An impact assessment of moisture changes in clay soils affe... 详细信息

关键词： Moisture Clay soil Freezing Numerical modelling

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

作者： i·阿西莫夫(i Asimov)

学校读者我要写书评

暂无评论

Seasonal and Temporal Variations in Volatile Organic Compounds in indoor and Outdoor Air in Al-Jahra City, Kuwait

引用

Journal of Environmental Protection 2014年第4期5卷 310-326页

作者： Nabeel M. Al-Khulaifi Humood F. Al-Mudhaf Raslan Alenezi Abdel-Sattar i. Abu-Shady Mustafa i. Selim Department of Chemical Engineering Technology College of Technological Studies Public Authority for Applied Education and Training (PAAET) Adailiyah Kuwait Department of Environmental Health College of Health Sciences Public Authority for Applied Education and Training (PAAET) Adailiyah Kuwait Department of Pharmacology and Toxicology Brody School of Medicine East Carolina University Greenville USA

indoor and outdoor air samples were simultaneously collected from the largest office building in Jahra City during 57 sampling events between August 2010 and November 2011. The collected samples were analyzed for 78 volatile organic compounds (VOCs) using CO2 cryogenic preconcentration and GC/MS analysis. Of the 48 VOCs detected, the toluene concentration exceeded the recommended air quality guidelines in 2% of the outdoor samples, and the benzene concentration exceeded these guidelines in 17.5% and 19.5% of the indoor and outdoor samples, respectively. industrial and vehicle emissions were negligible. Emissions from oil fields, various crude oil production and flaring activities in the north were major sources of VOCs in the ambient air. The VOC profiles;seasonal, monthly, and weekday/weekend variations;and their effects on ozone formation potentials are discussed. The results indicate that the most abundant class of chemical compounds was oxygenated compounds, of which acetone, acetaldehyde, propanal, methanol, ethanol, and 2-propanol were the most dominant species. Propene and toluene were the most abundant species of aliphatic and aromatic hydrocarbons, respectively.

关键词： BTEX Photochemical Reactivity Weekend Effect VOC Profiles Office Buildings

来源：

维普期刊数据库评论

在线全文

维普期刊数据库

学校读者我要写书评

暂无评论

定量化学分析

定量化学分析

引用

作者： i.M.·科尔索夫(i.M. Kolthoff)

来源：南通市图书馆图书评论

学校读者我要写书评

暂无评论

赎罪

引用

作者： (英)i.·麦克尤恩

来源：南通市图书馆图书评论

学校读者我要写书评

暂无评论

欢迎您,

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案：

请选择收藏分类：

通借通还

欢迎您,

建议与咨询 留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

时间限定

文献类型

馆藏选择

核心期刊

语言

文献类型

帮助

文字说明：

检索规则说明：

检索范例：

分类表

所选分类

限定检索结果

文献类型

馆藏范围

日期分布

学科分类号

主题

机构

作者

语言

在线全文

在线全文

在线全文

在线全文

在线全文

请选择保存的检索档案： 新增检索档案 确定 取消

请选择收藏分类： 新增自定义分类 确定 取消

通借通还

建议与咨询留下您的常用邮箱和电话号码，以便我们向您反馈解决方案和替代方法

请选择保存的检索档案：

请选择收藏分类：